G R Kaufmann

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, Level 2, 376 Victoria Street, NSW 2010, Sydney, Australia
    Curr Opin Microbiol 3:508-14. 2000
  2. ncbi request reprint Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    AIDS 14:959-69. 2000
  3. ncbi request reprint Impact of early HIV-1 RNA and T-lymphocyte dynamics during primary HIV-1 infection on the subsequent course of HIV-1 RNA levels and CD4+ T-lymphocyte counts in the first year of HIV-1 infection. Sydney Primary HIV Infection Study Group
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Sydney, New South Wales, Australia
    J Acquir Immune Defic Syndr 22:437-44. 1999
  4. ncbi request reprint Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia
    J J Zaunders
    Centre for Immunology, St Vincent s Hospital, UNSW, Darlinghurst, Australia 2010 Australia
    J Infect Dis 180:320-9. 1999
  5. ncbi request reprint Phenotypic analysis of CD8+ T lymphocytes in a cohort of HIV type 1-infected patients treated with saquinavir, ritonavir, and two nucleoside analogs for 1 year, and association with plasma HIV type 1 RNA
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW, Australia
    AIDS Res Hum Retroviruses 15:963-72. 1999
  6. ncbi request reprint Increased turnover of CCR5+ and redistribution of CCR5- CD4 T lymphocytes during primary human immunodeficiency virus type 1 infection
    J J Zaunders
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    J Infect Dis 183:736-43. 2001
  7. ncbi request reprint Novel deletion of HIV type 1 reverse transcriptase residue 69 conferring selective high-level resistance to nevirapine
    K Suzuki
    Centre for Immunology, St Vincent s Hospital, Sydney, NSW 2010, Australia
    AIDS Res Hum Retroviruses 17:1293-6. 2001
  8. ncbi request reprint Impact of HIV type 1 protease, reverse transcriptase, cleavage site, and p6 mutations on the virological response to quadruple therapy with saquinavir, ritonavir, and two nucleoside analogs
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, Sydney NSW 2010, Australia
    AIDS Res Hum Retroviruses 17:487-97. 2001
  9. ncbi request reprint Primary HIV-1 infection: a review of clinical manifestations, immunologic and virologic changes
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Sydney, Australia
    AIDS Patient Care STDS 12:759-67. 1998
  10. ncbi request reprint Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study
    A Carr
    HIV Medicine Unit and Centre for Immunology, St Vincent s Hospital, Sydney, NSW, Australia
    Lancet 353:2093-9. 1999

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, Level 2, 376 Victoria Street, NSW 2010, Sydney, Australia
    Curr Opin Microbiol 3:508-14. 2000
    ..Triple combination therapy that includes a non-nucleoside reverse transcriptase inhibitor can therefore be regarded as an effective alternative first-line treatment of HIV-1 infection...
  2. ncbi request reprint Long-term immunological response in HIV-1-infected subjects receiving potent antiretroviral therapy
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, St Vincent s Hospital, Sydney, New South Wales, Australia
    AIDS 14:959-69. 2000
    ..To determine the long-term T-lymphocyte response to highly active antiretroviral therapy (HAART) and to define predictors of the immunological response...
  3. ncbi request reprint Impact of early HIV-1 RNA and T-lymphocyte dynamics during primary HIV-1 infection on the subsequent course of HIV-1 RNA levels and CD4+ T-lymphocyte counts in the first year of HIV-1 infection. Sydney Primary HIV Infection Study Group
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Sydney, New South Wales, Australia
    J Acquir Immune Defic Syndr 22:437-44. 1999
    ..Nadir viral load was the strongest predictor of HIV-1 RNA levels as well as of CD4+ counts at 6 to 12 months. An early decline of CD4+ T lymphocytes may be a useful clinical prognostic marker for rapid disease progression...
  4. ncbi request reprint Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia
    J J Zaunders
    Centre for Immunology, St Vincent s Hospital, UNSW, Darlinghurst, Australia 2010 Australia
    J Infect Dis 180:320-9. 1999
    ..The persistence of HIV-1 DNA together with increased CD8 T lymphocyte turnover and activation indicate continued expression of viral antigens...
  5. ncbi request reprint Phenotypic analysis of CD8+ T lymphocytes in a cohort of HIV type 1-infected patients treated with saquinavir, ritonavir, and two nucleoside analogs for 1 year, and association with plasma HIV type 1 RNA
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW, Australia
    AIDS Res Hum Retroviruses 15:963-72. 1999
    ..A complete normalization of immunologic changes of CD8+ T lymphocytes would therefore require a more potent drug regimen or a longer duration of therapy...
  6. ncbi request reprint Increased turnover of CCR5+ and redistribution of CCR5- CD4 T lymphocytes during primary human immunodeficiency virus type 1 infection
    J J Zaunders
    Centre for Immunology, St Vincent s Hospital, Darlinghurst, NSW 2010, Australia
    J Infect Dis 183:736-43. 2001
    ..In contrast, in acute EBV infection, proliferating CCR5+ CD4 T cells accumulated to very high levels, suggesting they have an important role in the early antiviral response, which may be impaired in HIV-1 infection...
  7. ncbi request reprint Novel deletion of HIV type 1 reverse transcriptase residue 69 conferring selective high-level resistance to nevirapine
    K Suzuki
    Centre for Immunology, St Vincent s Hospital, Sydney, NSW 2010, Australia
    AIDS Res Hum Retroviruses 17:1293-6. 2001
    ..Our findings provide evidence that the deletion of RT residue 69 selectively confers high-level NVP resistance...
  8. ncbi request reprint Impact of HIV type 1 protease, reverse transcriptase, cleavage site, and p6 mutations on the virological response to quadruple therapy with saquinavir, ritonavir, and two nucleoside analogs
    G R Kaufmann
    National Centre in HIV Epidemiology and Clinical Research, Sydney NSW 2010, Australia
    AIDS Res Hum Retroviruses 17:487-97. 2001
    ..The relationship between mutations of cleavage sites or C-terminal p6* residues and protease mutations suggests that these alterations may serve a compensatory role, increasing viral fitness...
  9. ncbi request reprint Primary HIV-1 infection: a review of clinical manifestations, immunologic and virologic changes
    G R Kaufmann
    Centre for Immunology, St Vincent s Hospital, Sydney, Australia
    AIDS Patient Care STDS 12:759-67. 1998
    ..Cytokines have been shown to play a role in primary HIV-1 infection, and the therapy of primary infection has gained more interest due to the introduction of potent triple combinations, including protease inhibitors...
  10. ncbi request reprint Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study
    A Carr
    HIV Medicine Unit and Centre for Immunology, St Vincent s Hospital, Sydney, NSW, Australia
    Lancet 353:2093-9. 1999
    ..We studied the natural course of the syndrome to develop diagnostic criteria and identifying markers that predict its severity...