Stephan Karl

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. pmc A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
    Malar J 8:294. 2009
  2. pmc Mathematical modeling of malaria infection with innate and adaptive immunity in individuals and agent-based communities
    David Gurarie
    Department of Mathematics, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS ONE 7:e34040. 2012
  3. pmc Nuclear magnetic resonance: a tool for malaria diagnosis?
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Australia
    Am J Trop Med Hyg 85:815-7. 2011
  4. pmc Short report: Quantification of Plasmodium falciparum gametocytes by magnetic fractionation
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    Am J Trop Med Hyg 84:158-60. 2011
  5. pmc A sub-microscopic gametocyte reservoir can sustain malaria transmission
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    PLoS ONE 6:e20805. 2011
  6. pmc Parameterization of high magnetic field gradient fractionation columns for applications with Plasmodium falciparum infected human erythrocytes
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Malar J 9:116. 2010
  7. pmc A comparison of the sensitivities of detection of Plasmodium falciparum gametocytes by magnetic fractionation, thick blood film microscopy, and RT-PCR
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
    Malar J 8:98. 2009
  8. pmc The iron distribution and magnetic properties of schistosome eggshells: implications for improved diagnostics
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    PLoS Negl Trop Dis 7:e2219. 2013

Detail Information

Publications8

  1. pmc A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
    Malar J 8:294. 2009
    ..falciparum lactate dehydrogenase assay, the tritiated hypoxanthine incorporation assay, a previously described Sybr Green based plate reader assay and light microscopy...
  2. pmc Mathematical modeling of malaria infection with innate and adaptive immunity in individuals and agent-based communities
    David Gurarie
    Department of Mathematics, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS ONE 7:e34040. 2012
    ....
  3. pmc Nuclear magnetic resonance: a tool for malaria diagnosis?
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Australia
    Am J Trop Med Hyg 85:815-7. 2011
    ..2% parasitemia). Thus, our preliminary NMR approach, although providing very rapid measurements, is unlikely to achieve the required sensitivity and specificity for malaria diagnosis, unless a preliminary concentration step is performed...
  4. pmc Short report: Quantification of Plasmodium falciparum gametocytes by magnetic fractionation
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    Am J Trop Med Hyg 84:158-60. 2011
    ..Quantitative analysis above this threshold is difficult because of an over-abundance of gametocytes. The lower limit was 0.1 gametocytes/μL, and there is a significant probability of a false-negative result below this level...
  5. pmc A sub-microscopic gametocyte reservoir can sustain malaria transmission
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    PLoS ONE 6:e20805. 2011
    ..These techniques indicate a significant number of people carry gametocyte densities that fall below the conventional threshold of detection achieved by standard light microscopy (LM)...
  6. pmc Parameterization of high magnetic field gradient fractionation columns for applications with Plasmodium falciparum infected human erythrocytes
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Malar J 9:116. 2010
    ..falciparum gametocytes. The aim of the present study was to quantitatively characterize the magnetic fractionation process and thus enable optimization of protocols developed for specific uses...
  7. pmc A comparison of the sensitivities of detection of Plasmodium falciparum gametocytes by magnetic fractionation, thick blood film microscopy, and RT-PCR
    Stephan Karl
    School of Physics, M013, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
    Malar J 8:98. 2009
    ....
  8. pmc The iron distribution and magnetic properties of schistosome eggshells: implications for improved diagnostics
    Stephan Karl
    School of Physics, The University of Western Australia, Crawley, Western Australia, Australia
    PLoS Negl Trop Dis 7:e2219. 2013
    ..The mechanism of formation of the conjugates remains unexplained and may either be related to specific surface characteristics of eggs and microspheres or to their magnetic properties...