Graeme Jones

Summary

Affiliation: University of Tasmania
Country: Australia

Publications

  1. ncbi request reprint The effect of treatment on radiological progression in rheumatoid arthritis: a systematic review of randomized placebo-controlled trials
    G Jones
    Menzies Centre for Population Health Research, GPO Box 252 23, Hobart, Tasmania 7000
    Rheumatology (Oxford) 42:6-13. 2003
  2. ncbi request reprint Association of prevalent and incident knee cartilage defects with loss of tibial and patellar cartilage: a longitudinal study
    Changhai Ding
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 52:3918-27. 2005
  3. ncbi request reprint Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:776-84. 2007
  4. pmc Tocilizumab: a review of its safety and efficacy in rheumatoid arthritis
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    Clin Med Insights Arthritis Musculoskelet Disord 3:81-9. 2010
  5. pmc Effect of biologic therapy on radiological progression in rheumatoid arthritis: what does it add to methotrexate?
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Tasmania, Australia
    Biologics 6:155-61. 2012
  6. doi request reprint The association between breastfeeding, maternal smoking in utero, and birth weight with bone mass and fractures in adolescents: a 16-year longitudinal study
    G Jones
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7001, Australia
    Osteoporos Int 24:1605-11. 2013
  7. pmc Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
    Yuelong Cao
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia
    Trials 13:131. 2012
  8. pmc A randomized single blind crossover trial comparing leather and commercial wrist splints for treating chronic wrist pain in adults
    Jill Thiele
    Occupational Therapy Department, Royal Hobart Hospital, Hobart, Australia
    BMC Musculoskelet Disord 10:129. 2009
  9. pmc The design of a valid and reliable questionnaire to measure osteoporosis knowledge in women: the Osteoporosis Knowledge Assessment Tool (OKAT)
    Tania M Winzenberg
    Menzies Centre for Population Health Research, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 4:17. 2003
  10. pmc Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study
    Miranda L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, 89 Commercial Road, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Arthritis Res Ther 10:R58. 2008

Collaborators

Detail Information

Publications133 found, 100 shown here

  1. ncbi request reprint The effect of treatment on radiological progression in rheumatoid arthritis: a systematic review of randomized placebo-controlled trials
    G Jones
    Menzies Centre for Population Health Research, GPO Box 252 23, Hobart, Tasmania 7000
    Rheumatology (Oxford) 42:6-13. 2003
    ..To undertake a systematic review of randomized placebo-controlled trials to assess and rank the efficacy of pharmacological interventions in preventing radiological progression of rheumatoid arthritis...
  2. ncbi request reprint Association of prevalent and incident knee cartilage defects with loss of tibial and patellar cartilage: a longitudinal study
    Changhai Ding
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 52:3918-27. 2005
    ..To describe the association between prevalent and incident knee cartilage defects and loss of knee cartilage in male and female adults...
  3. ncbi request reprint Meniscal tear as an osteoarthritis risk factor in a largely non-osteoarthritic cohort: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:776-84. 2007
    ..To examine the associations between meniscal tear, knee structure, osteoarthritis (OA) risk factors, radiographic change, and symptoms in a largely non-osteoarthritic cohort...
  4. pmc Tocilizumab: a review of its safety and efficacy in rheumatoid arthritis
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    Clin Med Insights Arthritis Musculoskelet Disord 3:81-9. 2010
    ..In summary, there is sufficient evidence to make TCZ a first line biologic therapy for rheumatoid arthritis especially for those who are unable to take methotrexate or who fail anti-TNF therapy...
  5. pmc Effect of biologic therapy on radiological progression in rheumatoid arthritis: what does it add to methotrexate?
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Tasmania, Australia
    Biologics 6:155-61. 2012
    ....
  6. doi request reprint The association between breastfeeding, maternal smoking in utero, and birth weight with bone mass and fractures in adolescents: a 16-year longitudinal study
    G Jones
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7001, Australia
    Osteoporos Int 24:1605-11. 2013
    ..The results suggest that breastfeeding is associated with higher bone mass and lower fracture risk at age 16 but not in utero smoking or birth weight...
  7. pmc Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
    Yuelong Cao
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, TAS, 7000, Australia
    Trials 13:131. 2012
    ....
  8. pmc A randomized single blind crossover trial comparing leather and commercial wrist splints for treating chronic wrist pain in adults
    Jill Thiele
    Occupational Therapy Department, Royal Hobart Hospital, Hobart, Australia
    BMC Musculoskelet Disord 10:129. 2009
    ..To compare the effectiveness of a custom-made leather wrist splint (LS) with a commercially available fabric splint (FS) in adults with chronic wrist pain...
  9. pmc The design of a valid and reliable questionnaire to measure osteoporosis knowledge in women: the Osteoporosis Knowledge Assessment Tool (OKAT)
    Tania M Winzenberg
    Menzies Centre for Population Health Research, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 4:17. 2003
    ..However, there are few validated instruments for measuring osteoporosis knowledge levels. The aim of this study was to design a valid and reliable instrument to measure osteoporosis knowledge in Australian women...
  10. pmc Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study
    Miranda L Davies-Tuck
    Department of Epidemiology and Preventive Medicine, Monash University, Central and Eastern Clinical School, 89 Commercial Road, Alfred Hospital, Melbourne, Victoria 3004, Australia
    Arthritis Res Ther 10:R58. 2008
    ..Joint loading mediated via gait parameters may be associated with meniscal tears, and determining whether such an association exists was the aim of this study...
  11. pmc Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume
    Changhai Ding
    Menzies Research Institute, University of Tasmania, 199 Macquarie Street, Hobart 7000, Australia
    Arthritis Res Ther 9:R21. 2007
    ....
  12. pmc Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years
    Anita E Wluka
    Department of Epidemiology and Preventive Medicine, Monash University Central and Eastern Clinical School, Alfred Hospital, Commercial Road, Melbourne, VIC 3004, Australia
    Arthritis Res Ther 8:R90. 2006
    ..This may enable the prediction of cartilage change in an individual. The only significant factor affecting the loss of medial tibial cartilage was baseline knee pain, possibly through altered joint loading...
  13. ncbi request reprint Maternal diet during pregnancy is associated with bone mineral density in children: a longitudinal study
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    Eur J Clin Nutr 54:749-56. 2000
    ..To describe the association between maternal diet during the third trimester of pregnancy and bone mass in 8 y-old male and female children...
  14. ncbi request reprint Skeletal age deviation assessed by the Tanner-Whitehouse 2 method is associated with bone mass and fracture risk in children
    Graeme Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Bone 36:352-7. 2005
    ..SAD is simple to measure and gives additional information regarding bone health and fracture risk in children...
  15. ncbi request reprint The AMBITION trial: tocilizumab monotherapy for rheumatoid arthritis
    Graeme Jones
    Musculoskeletal Unit, Menzies Research Institute, Private Bag 23, Hobart Tasmania 7001, Australia
    Expert Rev Clin Immunol 6:189-95. 2010
    ..Long-term efficacy and safety follow-up is ongoing. This trial supports the use of TCZ as monotherapy and suggests it should be regarded as a first-line biologic therapy...
  16. ncbi request reprint Low bone mass in premenopausal parous women: identification and the effect of an information and bone density feedback program
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    J Clin Densitom 2:109-15. 1999
    ..Identification of these subjects by clinical risk factors is good but suboptimal, suggesting that measurement of BMD may be necessary to target most accurately and effectively those at highest risk...
  17. ncbi request reprint Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females
    G Jones
    Menzies Centre for Population Health Research, GPO Box 252 23, Tasmania 7000, Hobart, Australia
    Osteoarthritis Cartilage 12:169-74. 2004
    ..To describe the association between early radiographic osteoarthritis of the knee (ROA), knee cartilage volume and tibial bone surface area...
  18. doi request reprint Physical activity and osteoarthritis of the knee: can MRI scans shed more light on this issue?
    Graeme Jones
    Menzies Research Institute Tasmania, Tasmania, Australia
    Phys Sportsmed 39:55-61. 2011
    ..In the meantime, it appears safe to prescribe exercise in later life without major concern for structural deterioration, although caution is appropriate in those with bone marrow lesions until more information becomes available...
  19. ncbi request reprint Water fluoridation, bone mass and fracture: a quantitative overview of the literature
    G Jones
    Menzies Centre for Population Health Research, Tasmania
    Aust N Z J Public Health 23:34-40. 1999
    ..to address the following research questions: Is water fluoridation associated with altered fracture risk at a population level and are the differences between studies consistent with confounding or chance variation between studies?..
  20. pmc Genetic mechanisms of knee osteoarthritis: a population based case-control study
    G Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Ann Rheum Dis 63:1255-9. 2004
    ..To compare subjects who had at least one parent with a total knee replacement for severe primary knee osteoarthritis with age and sex matched controls who had no family history of knee osteoarthritis..
  21. ncbi request reprint Vitamin D insufficiency in adolescent males in Southern Tasmania: prevalence, determinants, and relationship to bone turnover markers
    Graeme Jones
    Menzies Research Institute, Private Bag 23, 7000, Hobart, Tasmania, Australia
    Osteoporos Int 16:636-41. 2005
    ..These data suggest that a 25(OH)D3 level of at least 43-55 nmol/l is required for optimal bone health in children...
  22. ncbi request reprint Vitamin D levels in prepubertal children in Southern Tasmania: prevalence and determinants
    G Jones
    Menzies Centre for Population Health Research, Hobart
    Eur J Clin Nutr 53:824-9. 1999
    ..To describe the prevalence and determinants of 25-hydroxy D3(25(OH)D) in children...
  23. ncbi request reprint Which bone mass measures discriminate adolescents who have fractured from those who have not?
    G Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania, Australia, 7000
    Osteoporos Int 19:251-5. 2008
    ..DXA measures and calcaneal ultrasound (but not radial ultrasound or metacarpal index) were associated with upper limb fracture, suggesting heel ultrasound is also a discriminator of fractures in children...
  24. ncbi request reprint Knee articular cartilage development in children: a longitudinal study of the effect of sex, growth, body composition, and physical activity
    Graeme Jones
    Menzies Centre for Population Health Research, GPO Box 252 23, Hobart, Tasmania, Australia 7000
    Pediatr Res 54:230-6. 2003
    ..These results provide novel data on articular cartilage development in humans. The long-term significance of these results with regard to osteoarthritis of the knee in later life remains hypothetical...
  25. ncbi request reprint Association between urinary potassium, urinary sodium, current diet, and bone density in prepubertal children
    G Jones
    Menzies Centre for Population Health Research, Hobart, Australia, and the College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada
    Am J Clin Nutr 73:839-44. 2001
    ..Our understanding of the role of nutrients in bone development in children is limited...
  26. ncbi request reprint A cross-sectional study of the association between Heberden's nodes, radiographic osteoarthritis of the hands, grip strength, disability and pain
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania 7000, Australia
    Osteoarthritis Cartilage 9:606-11. 2001
    ..To describe the associations between hand osteoarthritis (OA), pain and disability in males and females and to further validate the Australian/Canadian OA hand index (AUSCAN LK3.0)...
  27. ncbi request reprint Bone mass in prepubertal children: gender differences and the role of physical activity and sunlight exposure
    G Jones
    Menzies Center for Population Health Research, Hobart, Tasmania, Australia
    J Clin Endocrinol Metab 83:4274-9. 1998
    ..The magnitude of both gender and environmental differences in bone mass in this age group is substantial, suggesting that modification at this stage of life may influence peak bone mass and possibly fracture risk in later life...
  28. ncbi request reprint Symptomatic fracture incidence in those under 50 years of age in southern Tasmania
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    J Paediatr Child Health 38:278-83. 2002
    ..To document symptomatic fracture incidence in those aged under 50 years of age...
  29. ncbi request reprint A cross sectional study of the association between sex, smoking, and other lifestyle factors and osteoarthritis of the hand
    Graeme Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    J Rheumatol 29:1719-24. 2002
    ..To describe the association between sex, smoking, physical activity, occupation, and previous digit fracture and hand osteoarthritis (OA)...
  30. pmc Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
    G Jones
    Menzies Research Institute, University of Tasmania, Hobart, TAS 7001, Australia
    Ann Rheum Dis 69:88-96. 2010
    ..The anti-interleukin (IL) 6 receptor antibody tocilizumab inhibits signalling of IL6, a key cytokine in rheumatoid arthritis (RA) pathogenesis...
  31. ncbi request reprint The effect of a fracture protocol on hospital prescriptions after minimal trauma fractured neck of the femur: a retrospective audit
    Graeme Jones
    Menzies Research Institute, Private Bag 23, 7000 Hobart, Tasmania
    Osteoporos Int 16:1277-80. 2005
    ..79, 95%CI 0.96-3.36), but not age. In conclusion, a structural approach to changing hospital policy from the top down is effective at substantially increasing the usage of effective therapy after fractured neck of the femur...
  32. ncbi request reprint Asthma, inhaled corticosteroid use, and bone mass in prepubertal children
    G Jones
    Menzies Centre for Population Health Research, University of Tasmania, Hobart, Australia
    J Asthma 37:603-11. 2000
    ..These observations support current recommendations with regard to ICS usage in children, but require confirmation in longitudinal studies...
  33. ncbi request reprint Breastfeeding in early life and bone mass in prepubertal children: a longitudinal study
    G Jones
    Menzies Centre for Population Health Research, Hobart, Tasmania, Australia
    Osteoporos Int 11:146-52. 2000
    ..If this association is confirmed in other populations and persists until the attainment of peak bone mass then the implication would be that osteoporosis prevention programs need to start very early in the life cycle...
  34. ncbi request reprint Growth, children, and fractures
    Graeme Jones
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Curr Osteoporos Rep 2:75-8. 2004
    ..While prospective studies are required to confirm these risk factors, accumulating evidence now suggests that a substantial proportion of fractures in children are preventable...
  35. pmc Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Level 2, Surrey House, 199 Macquarie Street, Hobart, TAS 7000, Australia
    Arthritis Res Ther 8:R137. 2006
    ..They commonly coexist with chondral defects and ROA but only share common genetic mechanisms to a limited degree. They are also more common with increasing age, male sex, and increasing BMI...
  36. doi request reprint The association between objectively measured physical activity and knee structural change using MRI
    Dawn A Doré
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 72:1170-5. 2013
    ..This study describes the longitudinal association between objectively assessed physical activity (PA) and knee structural change measured using MRI...
  37. ncbi request reprint Correlates of knee pain in younger subjects
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, 7001, Australia
    Clin Rheumatol 26:75-80. 2007
    ..MRI and biochemical measures can add to radiographs in defining unexplained knee pain in younger subjects...
  38. ncbi request reprint The genetic contribution and relevance of knee cartilage defects: case-control and sib-pair studies
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    J Rheumatol 32:1937-42. 2005
    ....
  39. doi request reprint Subchondral bone and cartilage damage: a prospective study in older adults
    Dawn Dore
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 62:1967-73. 2010
    ..The aim of this study was to describe the association between baseline tibial bone area and tibial subchondral bone mineral density (BMD) with tibial cartilage defect development and cartilage volume loss...
  40. ncbi request reprint Knee structural alteration and BMI: a cross-sectional study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Obes Res 13:350-61. 2005
    ..To describe the associations among BMI, knee cartilage morphology, and bone size in adults...
  41. ncbi request reprint The genetic contribution to longitudinal changes in knee structure and muscle strength: a sibpair study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Tasmania, Australia
    Arthritis Rheum 52:2830-4. 2005
    ..To estimate the heritability of longitudinal changes in knee cartilage volume, chondral defects, subchondral bone size, and lower limb muscle strength...
  42. ncbi request reprint Determinants of skeletal age deviation in a cross-sectional study
    Sandi Powell
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    J Clin Endocrinol Metab 93:521-6. 2008
    ..Skeletal age deviation (SAD) is associated with bone mass and fracture risk in children, but factors determining this are unknown. The aim of this population-based cross-sectional study was to describe the factors associated with SAD...
  43. ncbi request reprint Natural history of knee cartilage defects and factors affecting change
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart
    Arch Intern Med 166:651-8. 2006
    ..Knee cartilage defects may play an important role in early osteoarthritis, but little is known about their natural history...
  44. ncbi request reprint Associations between serum levels of inflammatory markers and change in knee pain over 5 years in older adults: a prospective cohort study
    Oliver P Stannus
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Ann Rheum Dis 72:535-40. 2013
    ..To determine the association between inflammatory markers and change in knee pain over 5 years...
  45. pmc The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study
    Oliver P Stannus
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Arthritis Res Ther 12:R95. 2010
    ..The aim of this study was to describe the associations between leptin, IL-6, and hip radiographic osteoarthritis (ROA) in older adults...
  46. ncbi request reprint A prospective study of urinary electrolytes and bone turnover in adolescent males
    Graeme Jones
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Clin Nutr 26:619-23. 2007
    ..The aim of this 6-week prospective study was to describe the association between urinary electrolytes and bone turnover markers in a convenience sample of adolescent boys (N = 136, mean age 16 yr)...
  47. doi request reprint Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania
    Arthritis Rheum 60:1381-9. 2009
    ..To determine the associations between serum levels of vitamin D, sunlight exposure, and knee cartilage loss cross-sectionally and longitudinally in older adults...
  48. doi request reprint Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study
    Laura L Laslett
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Ann Rheum Dis 73:697-703. 2014
    ..Vitamin D is important for bone, cartilage and muscle function but there are few studies on its association with joint pain...
  49. pmc A prospective study of the impact of musculoskeletal pain and radiographic osteoarthritis on health related quality of life in community dwelling older people
    Laura L Laslett
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, TAS, Australia
    BMC Musculoskelet Disord 13:168. 2012
    ..Pain and radiographic changes are common in persons with osteoarthritis, but their relative contributions to quality of life are unknown...
  50. pmc A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, Tasmania, 7000, Australia
    Arthritis Res Ther 14:R13. 2012
    ..Bone marrow lesions (BMLs) play an important role in knee osteoarthritis, but their etiology is not well understood. The aim of this longitudinal study was to describe the association between dietary factors, serum lipids, and BMLs...
  51. doi request reprint Prospective study of self-reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community-dwelling older adults
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Arthritis Care Res (Hoboken) 64:30-7. 2012
    ..To examine the potential role of self-reported joint pain, stiffness, and dysfunction, and radiographic osteoarthritis (ROA), in sarcopenia progression and falls risk in older adults...
  52. pmc Bone marrow lesions predict site-specific cartilage defect development and volume loss: a prospective study in older adults
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, 7000, Australia
    Arthritis Res Ther 12:R222. 2010
    ....
  53. ncbi request reprint Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Osteoarthritis Cartilage 13:198-205. 2005
    ..To generate hypotheses regarding the associations between knee cartilage defects and knee radiographic osteoarthritis (ROA), cartilage volume, bone size and type II collagen breakdown in adults...
  54. ncbi request reprint A longitudinal study of the association between knee alignment and change in cartilage volume and chondral defects in a largely non-osteoarthritic population
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Rheumatol 34:181-6. 2007
    ..We investigated whether baseline malalignment of the knee predicts subsequent change in knee cartilage volume and chondral defects in subjects with and without radiographic knee osteoarthritis (OA)...
  55. ncbi request reprint Bone density interpretation and relevance in Caucasian children aged 9-17 years of age: insights from a population-based fracture study
    Graeme Jones
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Clin Densitom 9:202-9. 2006
    ..Five-yr wrist and forearm fracture risk has potential as a clinical endpoint of immediate relevance...
  56. ncbi request reprint Smoking interacts with family history with regard to change in knee cartilage volume and cartilage defect development
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 56:1521-8. 2007
    ..To describe the effects of smoking on change in knee cartilage volume and increases in knee cartilage defects, and to test for interaction between smoking and family history of osteoarthritis (OA)...
  57. ncbi request reprint Knee and hip radiographic osteoarthritis predict total hip bone loss in older adults: a prospective study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Bone Miner Res 25:858-65. 2010
    ..In conclusion, older subjects with radiographic hip and knee OA have higher total hip bone loss over 2.6 years regardless of symptoms, suggesting that consideration should be given to the monitoring of bone mass in these subjects...
  58. doi request reprint The association between jockey experience and race-day falls in flat racing in Australia
    Peta L Hitchens
    Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia
    Inj Prev 18:385-91. 2012
    ..The authors describe rates of occurrence and investigate risk factors for falls among less-experienced thoroughbred flat racing jockeys in Australia who commenced their race riding career between August 2002 and July 2009...
  59. pmc Bone density testing: an under-utilised and under-researched health education tool for osteoporosis prevention?
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart TAS 7001, Australia
    Nutrients 2:985-96. 2010
    ..2, 3.3). Fracture risk feedback based on BMD could potentially make an important contribution to osteoporosis prevention but confirmation of long-term benefits and cost effectiveness is needed before implementation can be recommended...
  60. pmc Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults
    Dawn Dore
    Menzies Research Institute Tasmania, University of Tasmania, Private Bag 23, Hobart, 7000, Australia
    Arthritis Res Ther 12:R223. 2010
    ....
  61. doi request reprint Correlates of subchondral BMD: a cross-sectional study
    Dawn Dore
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    J Bone Miner Res 24:2007-15. 2009
    ..10, p < 0.01). In conclusion, this study identified a large number of factors associated with sBMD, of which the most novel is cartilage defects. Longitudinal studies are required to address causality...
  62. ncbi request reprint Correlates of knee pain in older adults: Tasmanian Older Adult Cohort Study
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7001, Australia
    Arthritis Rheum 55:264-71. 2006
    ..To describe the association between chondral defects, bone marrow lesions, knee and hip radiographic osteoarthritis (OA), and knee pain...
  63. ncbi request reprint The genetic contribution to muscle strength, knee pain, cartilage volume, bone size, and radiographic osteoarthritis: a sibpair study
    Guangju Zhai
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 50:805-10. 2004
    ..To estimate the heritability of muscle strength, knee pain, cartilage volume, bone size, and radiographic osteoarthritis (ROA), and to assess whether heritability of the knee structural components is independent of ROA...
  64. ncbi request reprint Pharmacist-provided quantitative heel ultrasound screening for rural women at risk of osteoporosis
    Mark Naunton
    Faculty of Health Science, Tasmanian School of Pharmacy, University of Tasmania, Tasmania, Australia
    Ann Pharmacother 40:38-44. 2006
    ..Osteoporosis is underdiagnosed, and rural communities often have limited technical resources for the assessment of osteoporosis...
  65. pmc The effect on behavior and bone mineral density of individualized bone mineral density feedback and educational interventions in premenopausal women: a randomized controlled trial [NCT00273260]
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Public Health 6:12. 2006
    ....
  66. doi request reprint Circulating levels of inflammatory markers predict change in bone mineral density and resorption in older adults: a longitudinal study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania 7000, Australia
    J Clin Endocrinol Metab 93:1952-8. 2008
    ..IL-1, IL-6, and TNF-alpha play an important role in the pathogenesis of osteoporosis in animals; however, evidence that these play a similar role in bone loss in human studies is limited...
  67. ncbi request reprint A longitudinal study of the effect of sex and age on rate of change in knee cartilage volume in adults
    Changhai Ding
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    Rheumatology (Oxford) 46:273-9. 2007
    ..To describe the association between sex, age and rate of change in knee cartilage volume in adults...
  68. ncbi request reprint Factors associated with hip cartilage volume measured by magnetic resonance imaging: the Tasmanian Older Adult Cohort Study
    Guangju Zhai
    University of Tasmania, Hobart, Tasmania, Australia
    Arthritis Rheum 52:1069-76. 2005
    ....
  69. ncbi request reprint Sex differences in knee cartilage volume in adults: role of body and bone size, age and physical activity
    C Ding
    Menzies Centre for Population Health Research, University of Tasmania Hobart, Australia
    Rheumatology (Oxford) 42:1317-23. 2003
    ..To test the hypothesis that sex differences in knee cartilage volume may be mediated through body and bone size, age and/or physical activity...
  70. doi request reprint The association between parity and knee cartilage in young women
    Shuying Wei
    Menzies Research Institute Tasmania, 17 Liverpool Street, Hobart, Tasmania 7001, Australia
    Rheumatology (Oxford) 51:2039-45. 2012
    ..The aim of this study was to describe the association between parity, cartilage volume and cartilage defects in women aged 31-41 years...
  71. doi request reprint Association of baseline knee bone size, cartilage volume, and body mass index with knee cartilage loss over time: a longitudinal study in younger or middle-aged adults
    Benny Antony
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7000, Australia
    J Rheumatol 38:1973-80. 2011
    ..To determine the association of knee bone size, cartilage volume, and body mass index (BMI) at baseline with knee cartilage loss over 2 years in younger or middle-aged adults...
  72. pmc Optimal sampling of MRI slices for the assessment of knee cartilage volume for cross-sectional and longitudinal studies
    Guangju Zhai
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 6:10. 2005
    ..The aim of this study was to determine the optimal sampling of 1.5 mm thick slices of MRI scans to estimate knee cartilage volume in males and females for cross-sectional and longitudinal studies...
  73. ncbi request reprint The association between hormonal and reproductive factors and hand osteoarthritis
    Helen M Cooley
    Menzies Centre for Population Health Research, GPO Box 252 23, Hobart, Tasmania 7000, Australia
    Maturitas 45:257-65. 2003
    ..To describe the association of reproductive and hormonal factors with the presence and severity of hand osteoarthritis (OA) in Tasmanian women...
  74. pmc Genetic mechanisms of knee osteoarthritis: a population-based longitudinal study
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Arthritis Res Ther 8:R8. 2006
    ..Importantly, the cartilage changes are largely dependent on baseline differences in cartilage volume, tibial bone area, BMI and knee pain, suggesting that these factors might have a role in their initiation...
  75. ncbi request reprint Calcium supplements in healthy children do not affect weight gain, height, or body composition
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart, TAS 7001 Australia
    Obesity (Silver Spring) 15:1789-98. 2007
    ..The aim of this study was to use data from randomized controlled trials to determine whether calcium supplementation in healthy children affects weight or body composition...
  76. ncbi request reprint Physical activity and knee structural change: a longitudinal study using MRI
    Stella Foley
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Med Sci Sports Exerc 39:426-34. 2007
    ..Exercise therapy is effective in improving symptoms of knee osteoarthritis, but its effect on structural change remains unclear...
  77. ncbi request reprint A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis
    Velandai K Srikanth
    The Menzies Research Institute, Private Bag 23, Hobart, Tasmania 7001, Australia
    Osteoarthritis Cartilage 13:769-81. 2005
    ..To resolve uncertainty regarding sex differences in osteoarthritis (OA) by performing a meta-analysis of sex differences in OA prevalence, incidence and severity...
  78. pmc Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials
    Tania Winzenberg
    Menzies Research Institute, Private Bag 23, Hobart, TAS 7001, Australia
    BMJ 333:775. 2006
    ..To assess the effectiveness of calcium supplementation for improving bone mineral density in healthy children and to determine if any effect is modified by other factors and persists after supplementation stops...
  79. doi request reprint Do NSAIDs affect longitudinal changes in knee cartilage volume and knee cartilage defects in older adults?
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Am J Med 122:836-42. 2009
    ..The aim of this longitudinal study was to determine the associations between use of NSAIDs and changes in knee cartilage volume and knee cartilage defects over 2.9 years in older adults...
  80. doi request reprint Ambulatory activity, body composition, and lower-limb muscle strength in older adults
    David Scott
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Med Sci Sports Exerc 41:383-9. 2009
    ..The aim of this study was to describe associations of pedometer-determined AA with body fat and leg muscle parameters in community-dwelling 50- to 79-yr-olds...
  81. ncbi request reprint Risk-taking, coordination and upper limb fractures in children: a population based case-control study
    Deqiong Ma
    Menzies Research Institute, Private Bag 23, Hobart, Tasmania, Australia 7000
    Osteoporos Int 15:633-8. 2004
    ..These results inform the development of fracture prevention strategies in children...
  82. pmc Menstrual irregularity and bone mass in premenopausal women: cross-sectional associations with testosterone and SHBG
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    BMC Musculoskelet Disord 11:288. 2010
    ..This study aimed to describe the associations between menstrual pattern, testosterone, sex hormone binding globulin (SHBG) and bone mass in a population-based sample of premenopausal women...
  83. pmc Association between age and knee structural change: a cross sectional MRI based study
    C Ding
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Ann Rheum Dis 64:549-55. 2005
    ..To describe the associations between age, knee cartilage morphology, and bone size in adults...
  84. doi request reprint The association between maternal diet during pregnancy and bone mass of the children at age 16
    J Yin
    University of Tasmania, Hobart, Tasmania, Australia
    Eur J Clin Nutr 64:131-7. 2010
    ..However, it is unclear on the association between maternal nutrition during pregnancy and bone mass in their offspring at adolescence...
  85. ncbi request reprint Multifaceted educational program increases prescribing of preventive medication for corticosteroid induced osteoporosis
    Mark Naunton
    Tasmanian School of Pharmacy and Menzies Research Institute, Faculty of Health Science, University of Tasmania, Tasmania, Australia
    J Rheumatol 31:550-6. 2004
    ..We performed a controlled trial of a comprehensive educational program aimed at increasing the use of osteoporosis preventive therapy in patients prescribed longterm oral corticosteroids...
  86. doi request reprint Targeting IL-6 in the treatment of inflammatory and autoimmune diseases
    Changhai Ding
    Monash University, Central and Eastern Clinical School, Department of Epidemiology and Preventive Medicine, Commercial Road, Melbourne 3004, Australia
    Expert Opin Investig Drugs 18:1457-66. 2009
    ....
  87. doi request reprint Tracking of bone mass from childhood to adolescence and factors that predict deviation from tracking
    Stella Foley
    Menzies Research Institute, University of Tasmania Private Bag 23, Hobart, Tasmania, Australia
    Bone 44:752-7. 2009
    ..Body composition was the main predictor of altered tracking but environmental factors also appear important...
  88. doi request reprint The association between oral contraceptive use, bone mineral density and fractures in women aged 50-80 years
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Hobart, TAS 7001, Australia
    Contraception 84:357-62. 2011
    ..The associations between oral contraceptive (OC) use, bone mineral density (BMD) and the risk of fractures remain controversial...
  89. ncbi request reprint Dual energy X-ray absorptiometry
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Australia
    Aust Fam Physician 40:43-4. 2011
    ..The result - the bone mineral density (BMD) - can be reported at a number of sites. The most clinically useful are the lumbar spine, femoral neck and total hip (also termed the 'proximal femur')...
  90. ncbi request reprint When do bisphosphonates make the most sense?
    Tania Winzenberg
    Menzies Research Institute, Hobart, Tasmania, Australia
    J Fam Pract 60:18-28. 2011
  91. doi request reprint Oral contraceptive use and bone
    Shuying Wei
    Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7000, Australia
    Curr Osteoporos Rep 9:6-11. 2011
    ....
  92. ncbi request reprint B-cell-targeted therapy for systemic lupus erythematosus: an update
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    BioDrugs 22:239-49. 2008
    ..g. ocrelizumab) and agents that interrupt B-cell/T-cell interactions also have potential, and the efficacy of these, along with rituximab, belimumab and epratuzumab, needs to be determined by randomized controlled trials...
  93. ncbi request reprint Osteoarthritis management of the knee--treatment options post the NSAID cardiotoxicity controversy
    Jan Gartlan
    Menzies Research Institute, University of Tasmania, Australia
    Aust Fam Physician 36:717-8. 2007
    ..This article considers treatment options for osteoarthritis management of the knee post the 'NSAID cardiotoxicity controversy'...
  94. ncbi request reprint Ibandronate in benign bone disease
    Tania Winzenberg
    Menzies Research Institute, Level 2 199 Macquarie St, Hobart TAS Australia 7000, Australia
    Rev Recent Clin Trials 3:139-49. 2008
    ..Adverse effects and long-term safety data will also be reviewed...
  95. ncbi request reprint Anti-interleukin-6 receptor antibody treatment in inflammatory autoimmune diseases
    Changhai Ding
    Menzies Research Institute, Hobart, Tasmania, Australia
    Rev Recent Clin Trials 1:193-200. 2006
    ..Like other anti-cytokine immunotherapies, caution and close monitoring for the adverse events, especially infection, are necessary in subsequent clinical trials...
  96. ncbi request reprint Technology evaluation: MRA, Chugai
    Changhai Ding
    Menzies Centre for Population Health Research, University of Tasmania, 17 Liverpool Street, Hobart, 7000 TAS, Australia
    Curr Opin Mol Ther 5:64-9. 2003
    ..MRA is currently undergoing phase II clinical trials for these indications...
  97. pmc Effects of vitamin D supplementation on bone density in healthy children: systematic review and meta-analysis
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania, Hobart, TAS, Australia
    BMJ 342:c7254. 2011
    ..To determine the effectiveness of vitamin D supplementation for improving bone mineral density in children and adolescents and if effects vary with factors such as vitamin D dose and vitamin D status...
  98. ncbi request reprint Strontium ranelate--does it affect the management of postmenopausal osteoporosis?
    Tania Winzenberg
    Menzies Research Institute, University of Tasmania
    Aust Fam Physician 36:631-2. 2007
    ..This article considers whether the availability of strontium ranelate affects the management of postmenopausal osteoporosis...
  99. ncbi request reprint How important is MRI for detecting early osteoarthritis?
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Nat Clin Pract Rheumatol 4:4-5. 2008
  100. ncbi request reprint Belimumab Human Genome Sciences/Cambridge Antibody Technology/GlaxoSmithKline
    Changhai Ding
    Menzies Research Institute, University of Tasmania, Hobart 7000, Tasmania, Australia
    Curr Opin Investig Drugs 7:464-72. 2006
    ..By January 2006, belimumab had completed phase II clinical trials in SLE and RA; a phase III clinical SLE trial is scheduled to begin later this year...
  101. pmc The high prevalence of vitamin D insufficiency across Australian populations is only partly explained by season and latitude
    Ingrid A F van der Mei
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Environ Health Perspect 115:1132-9. 2007
    ..Inadequate sun exposure and dietary vitamin D intake can result in vitamin D insufficiency. However, limited data are available on actual vitamin D status and predictors in healthy individuals in different regions and by season...