Christine R Jenkins

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. pmc Health status in the TORCH study of COPD: treatment efficacy and other determinants of change
    Paul W Jones
    Department of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, UK
    Respir Res 12:71. 2011
  2. pmc COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age population
    Monica J Fletcher
    Education for Health, Warwick, UK
    BMC Public Health 11:612. 2011
  3. ncbi Salmeterol/fluticasone propionate combination therapy 50/250 microg twice daily is more effective than budesonide 800 microg twice daily in treating moderate to severe asthma
    C Jenkins
    Institute of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Respir Med 94:715-23. 2000
  4. ncbi COPD management. Part I. Strategies for managing the burden of established COPD
    C Jenkins
    Airways Group, Woolcock Institute of Medical Research, Camperdown, New South Wales, Australia
    Int J Tuberc Lung Dis 12:586-94. 2008
  5. pmc Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study
    Christine R Jenkins
    Woolcock Institute of Medical Research, Sydney, Australia
    Respir Res 10:59. 2009
  6. ncbi Efficacy and safety of high-dose budesonide/formoterol (Symbicort) compared with budesonide administered either concomitantly with formoterol or alone in patients with persistent symptomatic asthma
    Christine Jenkins
    Woolcock Institute of Medical Research, Camperdown, New South Wales, Australia
    Respirology 11:276-86. 2006
  7. doi Seasonality and determinants of moderate and severe COPD exacerbations in the TORCH study
    C R Jenkins
    Woolcock Institute of Medical Research, PO Box M77, Missenden Road, Camperdown, Sydney NSW 2050, Australia
    Eur Respir J 39:38-45. 2012
  8. ncbi Distinguishing asthma and chronic obstructive pulmonary disease: why, why not and how?
    Christine R Jenkins
    Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, PO Box M77, Missenden Road, Camperdown, NSW 2050, Australia
    Med J Aust 183:S35-7. 2005
  9. pmc Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice
    Christine Jenkins
    Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    BMJ 328:434. 2004
  10. ncbi An update on asthma management
    C Jenkins
    Department of Thoracic Medicine, Concord Hospital, Sydney, New South Wales, Australia
    Intern Med J 33:365-71. 2003

Detail Information

Publications41

  1. pmc Health status in the TORCH study of COPD: treatment efficacy and other determinants of change
    Paul W Jones
    Department of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, UK
    Respir Res 12:71. 2011
    ..Little is known about factors that determine health status decline in clinical trials of COPD...
  2. pmc COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age population
    Monica J Fletcher
    Education for Health, Warwick, UK
    BMC Public Health 11:612. 2011
    ..The burden of disease is known to be high, though less is known about those of a younger age. The aim of this study was to investigate the wider personal, economic and societal burden of COPD on a cross country working-age cohort...
  3. ncbi Salmeterol/fluticasone propionate combination therapy 50/250 microg twice daily is more effective than budesonide 800 microg twice daily in treating moderate to severe asthma
    C Jenkins
    Institute of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Respir Med 94:715-23. 2000
    ..These results demonstrate that SFC 50/250 microg twice daily is superior to budesonide 800 microg twice daily in the management of patients with moderate to severe asthma who are symptomatic on their existing dose of corticosteroid...
  4. ncbi COPD management. Part I. Strategies for managing the burden of established COPD
    C Jenkins
    Airways Group, Woolcock Institute of Medical Research, Camperdown, New South Wales, Australia
    Int J Tuberc Lung Dis 12:586-94. 2008
    ..Pulmonary rehabilitation plays an important role in improving exercise capacity at all severities of COPD, and should be widely available...
  5. pmc Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study
    Christine R Jenkins
    Woolcock Institute of Medical Research, Sydney, Australia
    Respir Res 10:59. 2009
    ..However, there are only limited data about the influence of GOLD severity staging on the effectiveness of SFC, particularly in patients with milder disease...
  6. ncbi Efficacy and safety of high-dose budesonide/formoterol (Symbicort) compared with budesonide administered either concomitantly with formoterol or alone in patients with persistent symptomatic asthma
    Christine Jenkins
    Woolcock Institute of Medical Research, Camperdown, New South Wales, Australia
    Respirology 11:276-86. 2006
    ..The authors assessed the efficacy and safety of a higher dose of budesonide/formoterol in patients with persistent symptomatic asthma...
  7. doi Seasonality and determinants of moderate and severe COPD exacerbations in the TORCH study
    C R Jenkins
    Woolcock Institute of Medical Research, PO Box M77, Missenden Road, Camperdown, Sydney NSW 2050, Australia
    Eur Respir J 39:38-45. 2012
    ..7-0.8 (p<0.001); RR for MRC dyspnoea score 3 versus 1 and 2 combined 1.1, 95% CI 1.1-1.2 (p<0.001)). The effect of season was independent of these risk factors. COPD exacerbations and hospitalisations were more frequent in winter...
  8. ncbi Distinguishing asthma and chronic obstructive pulmonary disease: why, why not and how?
    Christine R Jenkins
    Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, PO Box M77, Missenden Road, Camperdown, NSW 2050, Australia
    Med J Aust 183:S35-7. 2005
    ..Maintain research into new drugs and targets for preventing progressive loss of lung function in asthma and COPD...
  9. pmc Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice
    Christine Jenkins
    Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    BMJ 328:434. 2004
    ..To reassess the prevalence of aspirin induced asthma and other issues related to the syndrome...
  10. ncbi An update on asthma management
    C Jenkins
    Department of Thoracic Medicine, Concord Hospital, Sydney, New South Wales, Australia
    Intern Med J 33:365-71. 2003
    ..Patient self-management education and optimal therapy are the keys to achieving better outcomes, although uncertainty remains about recommendations for mild asthma, despite new data...
  11. doi Development and validation of the Patient Asthma Concerns Tool (PACT) to identify the needs of older people with asthma
    Melanie A Crane
    CRC for Asthma and Airways, Sydney, NSW, Australia
    Respir Med 106:1501-8. 2012
    ..The aim of this study was to test the validity and reliability of a 14-item tool, to identify the unmet needs and concerns of older people with asthma...
  12. doi Down-titration from high-dose combination therapy in asthma: Removal of long-acting beta(2)-agonist
    Helen K Reddel
    Woolcock Institute of Medical Research, PO Box M77, Missenden Rd PO, Camperdown NSW 2050, Australia
    Respir Med 104:1110-20. 2010
    ..This 13-month double-blind study of patients taking high-dose combination therapy investigated the effect of discontinuation of LABA before ICS down-titration...
  13. ncbi A single high dose of inhaled corticosteroids: a possible treatment of asthma exacerbations
    Jorg D Leuppi
    Institute of Respiratory Medicine, University of Sydney, Australia
    Swiss Med Wkly 132:7-11. 2002
    ..However airway responsiveness and sputum eosinophils can be reduced within 6 hours by a single dose of inhaled corticosteroids...
  14. pmc Analysis of adherence to peak flow monitoring when recording of data is electronic
    Helen K Reddel
    Institute of Respiratory Medicine, Royal Prince Alfred Hospital and University of Sydney, PO Box M77, Missenden Road, Camperdown, NSW 2050, Australia
    BMJ 324:146-7. 2002
  15. doi Recruiting and retaining general practitioners to a primary care asthma-intervention study in Australia
    Smita Shah
    Primary Health Care Education and Research Unit, Sydney West Local Health District, Sydney, NSW 2145, Australia
    Aust J Prim Health 20:98-102. 2014
    ..Finally over the next 7 months, RM3 recruited 84 (12%) GPs and retained 75 (89%) GPs. In conclusion, use of a medical peer as the first contact was associated with the highest recruitment and retention rate...
  16. doi A snapshot of general practitioner attitudes, levels of confidence and self-reported paediatric asthma management practice
    Jessica K Roydhouse
    Woolcock Institute of Medical Research, Glebe, NSW 2037, Australia
    Aust J Prim Health 17:288-93. 2011
    ..These findings indicate gaps between GP attitudes and behaviours and highlights opportunities for interventions to improve paediatric asthma management...
  17. doi The association of comorbid anxiety and depression with asthma-related quality of life and symptom perception in adults
    Vandana M Deshmukh
    Woolcock Institute of Medical Research, Camperdown, NSW, Australia
    Respirology 13:695-702. 2008
    ..This study evaluated these associations in patients subsequent to an emergency department (ED) visit for asthma...
  18. ncbi Using discrete choice experiments to investigate subject preferences for preventive asthma medication
    Emily J Lancsar
    Cooperative Research Centre for Asthma, University of Sydney, Sydney, Australia
    Respirology 12:127-36. 2007
    ..This study was undertaken to explore patient preferences in relation to their current inhaled corticosteroid medication, a hypothetical preventer or no medication...
  19. ncbi Respiratory symptoms and illness in older Australians: the Burden of Obstructive Lung Disease (BOLD) study
    Brett G Toelle
    Department of Respiratory and Environmental Epidemiology, Woolcock Institute of Medical Research, Sydney, NSW, Australia
    Med J Aust 198:144-8. 2013
    ..To measure the prevalence of chronic obstructive pulmonary disease (COPD) among people aged 40 years or older in Australia...
  20. ncbi Asthma management and outcomes in Australia: a nation-wide telephone interview survey
    Guy B Marks
    Woolcock Institute of Medical Research, Sydney, New South Wales, Australia
    Respirology 12:212-9. 2007
    ..The aim of this study was to assess the burden of asthma and describe current asthma management in Australia...
  21. ncbi The needs of older people with asthma
    Nicole E Cousens
    Woolcock Institute of Medical Research, RPA Hospital, Sydney, New South Wales, Australia
    Aust Fam Physician 36:729-31. 2007
    ..Asthma is prevalent among elderly Australians but is often misdiagnosed and undertreated. Asthma presents with the same clinical features in the elderly as in the younger population...
  22. doi Does continuous use of inhaled corticosteroids improve outcomes in mild asthma? A double-blind randomised controlled trial
    Helen K Reddel
    Woolcock Institute of Medical Research and University of Sydney, Camperdown, New South Wales, Australia
    Prim Care Respir J 17:39-45. 2008
    ..To compare the effects of fluticasone and placebo on asthma control in patients with mild asthma...
  23. ncbi Effect of budesonide on the perception of induced airway narrowing in subjects with asthma
    Cheryl M Salome
    Institute of Respiratory Medicine, University of Sydney, Sydney, New South Wales, Australia
    Am J Respir Crit Care Med 165:15-21. 2002
    ..We conclude that treatment with budesonide enhances the perception of airway narrowing, but the effect is unrelated to budesonide dose, or to changes in circulating eosinophil markers...
  24. ncbi Improving paediatric asthma outcomes in primary health care: a randomised controlled trial
    Smita Shah
    Primary Health Care Education and Research Unit, Westmead Hospital, University of Sydney, Sydney, NSW
    Med J Aust 195:405-9. 2011
    ..To evaluate the effectiveness of the Practitioner Asthma Communication and Education (PACE) Australia program, an innovative communication and paediatric asthma management program for general practitioners...
  25. ncbi Feasibility study of a communication and education asthma intervention for general practitioners in Australia
    Smita Shah
    Primary Health Care Education and Research Unit, Primary and Community Health Network, Sydney West Area Health Service, Sydney, NSW 2145, Australia
    Aust J Prim Health 16:75-80. 2010
    ..The impact ofthe modified PACE Australia program on the processes and outcomes ofGP care ofchildren with asthma is now being measured in a randomised controlled trial...
  26. ncbi Anxiety, panic and adult asthma: a cognitive-behavioral perspective
    Vandana M Deshmukh
    Woolcock Institute of Medical Research, Camperdown, NSW, Australia
    Respir Med 101:194-202. 2007
    ..Trials evaluating CBT interventions in individuals with clinical anxiety manifestations and asthma may provide evidence of these interventions as an effective adjunct to improve asthma management and control...
  27. doi Unmet needs of older people with asthma: cross-sectional survey
    Dianne P Goeman
    CRC for Asthma and Airways, Sydney, NSW, Australia
    J Asthma 48:865-75. 2011
    ..Asthma in older people is a major cause of disease burden in Australia and is projected to increase over the next two decades. Current guidelines for asthma care rely predominantly on studies from younger populations...
  28. pmc Double blind randomised controlled trial of two different breathing techniques in the management of asthma
    C A Slader
    Faculty of Pharmacy, University of Sydney, New South Wales, Australia 2006
    Thorax 61:651-6. 2006
    ..This study also assessed the effect of peak flow monitoring on outcomes in patients using breathing techniques...
  29. ncbi Exasperations" of asthma: a qualitative study of patient language about worsening asthma
    Stephen D Vincent
    Woolcock Institute of Medical Research, Sydney, NSW, Australia
    Med J Aust 184:451-4. 2006
    ....
  30. doi Maintenance of vital capacity during repetitive breath-hold in a spearfishing competition
    Leigh M Seccombe
    Australian School of Advanced Medicine, Macquarie University, Australia
    Respirology 17:350-3. 2012
    ..Cough and a reduction in vital capacity have recently been reported following breath-hold dives to depths of 25-75 m. We sought to investigate whether repetitive dives to depths of less than 30 m would elicit similar effects...
  31. doi Glossopharyngeal insufflation causes lung injury in trained breath-hold divers
    Steven C S Chung
    Department of Thoracic Medicine, Concord Repatriation General Hospital, Concord, Sydney, New South Wales, Australia
    Respirology 15:813-7. 2010
    ..Although the potential for lung injury is evident, there is limited information available. The aim of this study was to examine whether there is any evidence of lung injury following GI, independent of diving...
  32. ncbi Asthma in older adults: a holistic, person-centred and problem-oriented approach
    Guy B Marks
    Woolcock Institute of Medical Research, Sydney, NSW, Australia
    Med J Aust 191:197-9. 2009
    ..Regardless of how obstructive lung disease is labelled, targeting treatment to components of the problem is the best solution...
  33. ncbi Complementary and alternative medicine use in asthma: who is using what?
    Cassandra A Slader
    Faculty of Pharmacy, University of Sydney, New South Wales, Australia
    Respirology 11:373-87. 2006
    ..Nevertheless, the high rates of CAM use reported in some studies indicate that CAM use should be taken into account when managing patients with asthma...
  34. ncbi Asthma in Indigenous Australians: so much yet to do for Indigenous lung health
    Christine R Jenkins
    Woolcock Institute of Medical Research, Sydney, NSW, Australia
    Med J Aust 190:530-1. 2009
    ..Indigenous Australians die of asthma at more than three times the rate of the rest of the nation...
  35. doi The use of non-invasive ventilation for the relief of dyspnoea in exacerbations of chronic obstructive pulmonary disease; a systematic review
    Tracy A Smith
    Cunningham Centre for Palliative Care, Sacred Heart Hospice, Sydney, Australia
    Respirology 17:300-7. 2012
    ..The objective of this systematic review was to identify, synthesize and interpret the data regarding the relief of dyspnoea afforded by NIV in patients admitted with acute respiratory failure occurring during AECOPD...
  36. ncbi Markers of airway inflammation and airway hyperresponsiveness in patients with well-controlled asthma
    J D Leuppi
    Institute of Respiratory Medicine, University of Sydney, New South Wales, Australia
    Eur Respir J 18:444-50. 2001
    ..Airway hyperresponsiveness in clinically well-controlled asthmatics appears to be independent of eosinophilic airway inflammation...
  37. ncbi Predictive markers of asthma exacerbation during stepwise dose reduction of inhaled corticosteroids
    J D Leuppi
    Institute of Respiratory Medicine, University of Sydney, New South Wales, Australia
    Am J Respir Crit Care Med 163:406-12. 2001
    ..These findings suggest that documentation of patient's AHR or sputum eosinophils may be useful in guiding the reduction of ICS doses...
  38. pmc When can personal best peak flow be determined for asthma action plans?
    H K Reddel
    Woolcock Institute of Medical Research, Camperdown, NSW, Australia
    Thorax 59:922-4. 2004
    ..Guidelines state that personal best PEF should be assessed over 2-3 weeks during good asthma control, but it is unclear how long to wait after commencing or changing treatment...
  39. ncbi Treatment of mild asthma
    Christine R Jenkins
    N Engl J Med 353:424-7; author reply 424-7. 2005
  40. ncbi Patient preferences for managing asthma: results from a discrete choice experiment
    Madeleine T King
    Centre for Health Economics Research and Evaluation, University of Technology Sydney, Australia
    Health Econ 16:703-17. 2007
    ..Demographic characteristics did not improve the model fit. This study illustrates how discrete choice experiments may be embedded in a clinical trial to provide insights into patient preferences...
  41. doi Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study
    Bartolome R Celli
    Tufts University School of Medicine, Pulmonary and Critical Care Division, Caritas St Elizabeth s Medical Center, Boston, MA 02135 2997, USA
    Am J Respir Crit Care Med 178:332-8. 2008
    ..Chronic obstructive pulmonary disease (COPD) is characterized by an accelerated decline in lung function. No drug has been shown conclusively to reduce this decline...