Research Topics
| Jereny R JassSummaryAffiliation: University of Queensland Country: Australia Publications
Research Grants
| Collaborators
|
Detail Information
Publications
DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patientsCoral V A Wynter
Conjoint Gastroenterology Laboratory, Clinical Research Centre, Queensland Institute of Medical Research, Brisbane, Queensland Australia
Int J Cancer 118:907-15. 2006..Genetic profiling of adenomas supports the concept that adenomas belonging to familial syndromes pursue a different pathway to tumorigenesis than their sporadic counterpar/ts from their earliest formation...
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathwaysJ R Jass
Department of Pathology, University of Queensland Medical School, Herston, Australia
J Clin Pathol 52:455-60. 1999....- Altered mucin expression in the gastrointestinal tract: a reviewJ R Jass
Department of Pathology, University of Queensland School of Medicine, Herston Road, Queensland 4006, Australia
J Cell Mol Med 5:327-51. 2001..As such they may serve as markers to explain pathogenesis and provide novel diagnostic and prognostic information... - Evolution of colorectal cancer: change of pace and change of directionJereny R Jass
Department of Pathology, School of Medicine, University of Queensland, Herston, Australia
J Gastroenterol Hepatol 17:17-26. 2002..Cancers in hereditary non-polyposis colorectal cancer show features of both classical (adenoma and APC mutation) and alternative pathways (rapid evolution, MSI-H and lack of chromosomal instability)... - Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instabilityJ R Jass
Department of Pathology, University of Queensland, Herston, Queensland 4006, Australia
Eur J Cancer 38:858-66. 2002.... - Familial colorectal cancer: pathology and molecular characteristicsJ R Jass
Department of Pathology, University of Queensland, Mayne Medical School, Herston, Australia
Lancet Oncol 1:220-6. 2000..Some of these, notably hyperplastic polyposis and mixed polyposis, may closely mimic FAP or HNPCC... - Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectumJ R Jass
Department of Pathology, The University of Queensland, and Conjoint Gastroenterology Laboratory, Royal Brisbane Hospital, Queensland, Australia
Histopathology 37:295-301. 2000..These mechanisms fit with clinical observations relating to sporadic MSI-H colorectal cancer, specifically proximal location, multiplicity, higher frequency among females and rapid evolution of early cancer... - Pathology of hereditary nonpolyposis colorectal cancerJ R Jass
Department of Pathology, University of Queensland Mayne Medical School, Australia
Ann N Y Acad Sci 910:62-73; discussion 73-4. 2000..Immunohistochemical staining for hMLH1 and hMSH2 identifies the underlying mutation in a proportion of cases. The colorectal adenoma is the usual precursor lesion in HNPCC, though serrated polyps are implicated in a small subset... - Broadsheet number 52: Molecular genetics of colorectal cancerJ R Jass
Department of Pathology, University of Queensland Medical School, Brisbane, Australia
Pathology 31:354-64. 1999..It is shown how the fundamental principle of genetic instability cuts across applied research, tissue diagnosis and clinical management with respect to both sporadic and inherited forms of colorectal cancer... - Towards a molecular classification of colorectal cancerJ R Jass
Department of Pathology, University of Queensland, Australia
Int J Colorectal Dis 14:194-200. 1999..It is likely that testing for DNA mismatch repair will be adopted as a routine for colorectal cancer as more is learned of the distinctive pathobiology and behaviour of MSS, MSI-L and MSI-H cancers... - Adenocarcinoma of colon differentiating as dome epithelium of gut-associated lymphoid tissueJ R Jass
Departments of Pathology, University of Queensland, Royal Brisbane Hospital, Queensland, Australia
Histopathology 36:116-20. 2000..An early adenocarcinoma of the ascending colon was confined to a mass of gut-associated lymphoid tissue (GALT). The first description of an adenocarcinoma of colon differentiating as dome epithelium is presented... - Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectumJ R Jass
Department of Pathology, University of Queensland, Mayne Medical School, Herston, Australia
Gut 47:43-9. 2000.... - Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylationTakeshi Nagasaka
Department of Gastroenterological Surgery and Surgical Oncology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
J Clin Oncol 22:4584-94. 2004..These changes may be important events in colorectal tumorigenesis... - Role of the pathologist in the diagnosis of hereditary non-polyposis colorectal cancerJeremy R Jass
McGill University, Montreal, Quebec, Canada
Dis Markers 20:215-24. 2004..Immunohistochemistry to demonstrate loss of expression of DNA mismatch repair genes serves as a highly reliable test of mismatch repair deficiency if antibodies to hMLH1, hMSH2, hMSH6 and hPMS2 are employed... - Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancerGraham Casey
Department of Cancer Biology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio 44195, USA
JAMA 293:799-809. 2005..Current data suggest that mismatch repair mutations are highly heterogeneous and that many mutations are not detected when conventional DNA sequencing alone is used... - Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancerJoanne Young
Conjoint Gastroenterology Laboratory, Queensland Institute of Medical Research, Herston, Australia
Clin Gastroenterol Hepatol 3:254-63. 2005..Here, we discuss their role in the development of other familial colorectal cancers (CRC). We studied non-FAP, non-HNPCC CRC families characterized by tumors that varied in their level of MSI between individual members... - Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancerMelissa C Southey
Genetic Epidemiology Laboratory, Department of Pathology, Australia
J Clin Oncol 23:6524-32. 2005..The relationships between mismatch repair (MMR) protein expression, microsatellite instability (MSI), family history, and germline MMR gene mutation status have not been studied on a population basis... - Serrated adenoma of the colorectum and the DNA-methylator phenotypeJeremy R Jass
Department of Pathology, McGill University, Duff Medical Building, 3775 University Street, Montreal, Quebec H3A 2B4, Canada
Nat Clin Pract Oncol 2:398-405. 2005..The current lack of guidelines for managing serrated polyps may explain the static incidence of proximal CRC, despite the falling incidence rates for left-sided CRC during the same time period... - Re: Ward et al. Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified. J Pathol 2005;207:377-384Jeremy R Jass
J Pathol 208:590-1. 2006 - Cancer risks for mismatch repair gene mutation carriers: a population-based early onset case-family studyMark A Jenkins
Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Victoria, Australia
Clin Gastroenterol Hepatol 4:489-98. 2006..These may be overestimates, due to analytic problems, and not generalizable. We estimated average cancer risks for mutations identified in population-based early onset colorectal cancer cases (probands) unselected for family history... - Tumor buds show reduced expression of laminin-5 gamma 2 chain in DNA mismatch repair deficient colorectal cancerEiji Shinto
Department of Pathology, McGill University, Montreal, Canada
Dis Colon Rectum 49:1193-202. 2006..It is hypothesized that tumor budding in this subset may lack biologic aggressiveness because it is not associated with aberrant expression of the independent prognostic factor, laminin-5 gamma 2... - Hereditary Non-Polyposis Colorectal Cancer: the rise and fall of a confusing termJeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec H3A 2B4, Canada
World J Gastroenterol 12:4943-50. 2006..The first step in characterizing these cancer families is to distinguish them from Lynch syndrome. The term HNPCC no longer serves any useful purpose and should be phased out... - The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literatureJoanne Young
Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Herston, Queensland 4006, Australia
Cancer Epidemiol Biomarkers Prev 15:1778-84. 2006..The tendency for these lesions to be multiple, associated with smoking, and to show frequent BRAF mutation and CIMP points to a defect that may result from interactions between the environment and a weakly penetrant genetic alteration... - Stability of BAT26 in Lynch syndrome colorectal tumoursLesley Jaskowski
Eur J Hum Genet 15:139-41; author reply 141-2. 2007 
Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer developmentKim Loh
Conjoint Gastroenterology Laboratory, Royal Brisbane and Women s Hospital Research Foundation Clinical Research Centre and Queensland Institute of Medical Research, Brisbane 4029, Australia
Genes Chromosomes Cancer 47:449-60. 2008..This study provides molecular and functional data supporting the importance of BMP3 silencing as an early and frequent event in colorectal tumors progressing via the serrated and traditional pathways...- Loss of APAF-1 expression is associated with tumour progression and adverse prognosis in colorectal cancerInti Zlobec
Department of Pathology, McGill University, Duff Medical Building, 3775 University Street, Montreal, Canada H3A 2B4
Eur J Cancer 43:1101-7. 2007..001). No methylation was found in the selected region of APAF-1. APAF-1 is a marker of tumour progression in MMR-proficient CRC and an independent adverse prognostic factor in MLH1-negative CRC... - Colorectal cancer: a multipathway diseaseJeremy R Jass
Department of Pathology, McGill University, Duff Medical Building, 3775 University Street, Montreal, Quebec H3A 2B4, Canada
Crit Rev Oncog 12:273-87. 2006..CRC comprises subgroups with particular clinical, pathological, and molecular features... - Loss of raf-1 kinase inhibitor protein expression is associated with tumor progression and metastasis in colorectal cancerParham Minoo
Department of Pathology, McGill University, Montreal, Canada
Am J Clin Pathol 127:820-7. 2007..Methylation analysis of 28 cases showed that loss of RKIP expression is unlikely to be due to promoter methylation.Loss of RKIP expression is a marker of tumor progression and distant metastasis in MMR-proficient and MMR-deficient CRCs... - Limitations of the adenoma-carcinoma sequence in colorectumJeremy R Jass
Clin Cancer Res 10:5969-70; author reply 5970. 2004 - HNPCC and sporadic MSI-H colorectal cancer: a review of the morphological similarities and differencesJeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada
Fam Cancer 3:93-100. 2004..Morphological features can assist is distinguishing such families from bona fide HNPCC families which they closely mimic... - Clinical significance of early-onset "sporadic" colorectal cancer with microsatellite instabilityJeremy R Jass
Dis Colon Rectum 46:1305-9. 2003 - Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancerVicki L J Whitehall
Conjoint Gastroenterology Laboratory, Clinical Research Centre, Royal Brisbane Hospital Research Foundation, Queensland 4029, Australia
Cancer Res 62:6011-4. 2002..004) and lower frequency of hMLH1 methylation (P < 0.001) in the latter. These data demonstrate that the separation of CRC into two nonoverlapping groups (MSI-H versus MSS/MSI-L) is a misleading oversimplification... - Emerging concepts in colorectal neoplasiaJeremy R Jass
Department of Molecular and Cellular Pathology, University of Queensland Medical School, Australia
Gastroenterology 123:862-76. 2002..If colorectal cancer is a heterogeneous disease comprising discrete subsets that evolve through different pathways, it is evident that these subsets will need to be studied individually in the future... - Pathogenesis of colorectal cancerJeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada, H3A2B4
Surg Clin North Am 82:891-904. 2002..Specifically, modern genomics will allow polyps and cancers to be grouped within pathogenic pathways on the basis of shared gene expression profiles. The era of molecular medicine has dawned for colorectal cancer... - Re: Tomlinson et al. Does MSI-low exist. J Pathol 2002; 197: 6-13Jeremy R Jass
J Pathol 199:267-9; author reply 269-70. 2003 - Emerging pathways in colorectal-cancer developmentAndrew M M Haydon
Department of Epidemiology and Preventive Medicine, Monash Medical School, Alfred Hospital, Prahran, Victoria, Australia
Lancet Oncol 3:83-8. 2002..Tumours may have high or low type C (cancer-related) CpG-island methylation. When methylation affects hMLH1 (mismatch repair gene), the resultant cancer has high MSI... - Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumorsNoralane M Lindor
Department of Medical Genetics, Mayo Foundation, Rochester, MN 55905, USA
J Clin Oncol 20:1043-8. 2002..To compare microsatellite instability (MSI) testing with immunohistochemical (IHC) detection of hMLH1 and hMSH2 in colorectal cancer... - Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genesJoanne Young
Conjoint Gastroenterology Laboratory, Royal Brisbane Hospital Foundation Clinical Research Centre, Bancroft Centre, Herston, Queensland, Australia
Pathology 34:529-33. 2002..Here we report our progress using denaturing gradient high-pressure liquid chromatography (DHPLC) in the screening of the mismatch repair genes MLH1 and MSH2 and in screening the APC and HPP1 tumour suppressor genes for mutations... - Serrated adenoma of the colorectum: a lesion with teethJeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada
Am J Pathol 162:705-8. 2003 - Role of inherited defects of MYH in the development of sporadic colorectal cancerTakeshi Kambara
Conjoint Gastroenterology Laboratory, Royal Brisbane and Women s Hospital Research Foundation and Queensland Institute of Medical Research, Brisbane, Australia
Genes Chromosomes Cancer 40:1-9. 2004..02). These results suggest that single germ-line variants of MYH may influence genetic pathways in CRC... - Allelic loss of a common microsatellite marker MYCL1: a useful prognostic factor of poor outcomes in colorectal cancerTakeshi Kambara
Department of Gastroenterological Surgery and Surgical Oncology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Clin Cancer Res 10:1758-63. 2004..Our aim in the present study was to determine whether allelic losses on 1p were likely to be of much value in predicting the prognosis of CRC cases... - Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer casesTakeshi Nagasaka
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Clin Cancer Res 9:5306-12. 2003.... - Molecular heterogeneity of colorectal cancer: Implications for cancer controlJeremy R Jass
Department of Cellular Pathology, St Mark s Hospital, Watford Road, Harrow, Middx HA1 3UJ, UK
Surg Oncol 16:S7-9. 2007..In particular, new strategies for detecting and managing sessile serrated polyps will need to be developed and evaluated... - Silencing of O6-methylguanine DNA methyltransferase in the absence of promoter hypermethylation in hepatocellular carcinomas from Australia and South AfricaNirmitha I Herath
Leukaemia Foundation of Queensland, Queensland Institute of Medical Research, Brisbane, QLD 4029, Australia
Oncol Rep 17:817-22. 2007..This suggests that epigenetic silencing of MGMT and microsatellite instability does not play an important role in this series of HCCs derived from different populations... - Recommendations for the reporting of surgically resected specimens of colorectal carcinomaJeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada
Hum Pathol 38:537-545. 2007.... - The MUC13 cell surface mucin is highly expressed by human colorectal carcinomasMichael D Walsh
Molecular Cancer Epidemiology Laboratory, Bancroft Centre, Queensland Institute of Medical Research, Herston, QLD, Australia
Hum Pathol 38:883-92. 2007..In summary, MUC13 was expressed abundantly by all colorectal cancers, with the highest expression in more poorly differentiated tumors... - Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patientsMichael D Walsh
Familial Cancer Laboratory and Molecular Cancer Epidemiology Laboratory, Queensland Institute of Medical Research, Herston, Australia
Clin Cancer Res 14:1692-700. 2008..The aim of this study was to determine the incidence of Lynch syndrome in a series of young-onset EC, and to identify molecular, clinical, and pathologic features that may alert clinicians to the presence of this disorder... - Node-negative colorectal cancer at high risk of distant metastasis identified by combined analysis of lymph node status, vascular invasion, and Raf-1 kinase inhibitor protein expressionInti Zlobec
Institute of Pathology, University Hospital of Basel, Basel, Switzerland
Clin Cancer Res 14:143-8. 2008.... - Recommendations for the reporting of surgically resected specimens of colorectal carcinoma: Association of Directors of Anatomic and Surgical PathologyJeremy R Jass
Department of Cellular Pathology, St Mark's Hospital, Harrow, England
Am J Clin Pathol 129:13-23. 2008 - Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancerInti Zlobec
Institute of Pathology, University Hospital of Basel, Schonbeinstrasse 40, Basel 4031, Switzerland
Virchows Arch 451:763-9. 2007.... - Colorectal cancer prevention in inflammatory bowel disease and the role of 5-aminosalicylic acid: a clinical review and updateDavid T Rubin
University of Chicago Medical Center, Chicago, IL 60637, USA
Inflamm Bowel Dis 14:265-74. 2008..This article provides a comprehensive overview of the issues discussed and should act as a guide to shaping the design of future studies in this area... - Multimarker phenotype predicts adverse survival in patients with lymph node-negative colorectal cancerInti Zlobec
Institute of Pathology, University Hospital of Basel, Basel, Switzerland
Cancer 112:495-502. 2008..The objective of this study was to define a multimarker prognostic model of 5-year survival in patients with lymph node-negative, mismatch repair (MMR)-proficient colorectal cancer (CRC)... - The "Fas counterattack" is not an active mode of tumor immune evasion in colorectal cancer with high-level microsatellite instabilityAileen M Houston
Department of Medicine, National University of Ireland Cork, Clinical Science Building, Cork University Hospital, Wilton, Cork, Ireland
Hum Pathol 39:243-50. 2008..059). Together, these findings suggest that the abundance of TILs found in MSI-H tumors may be due to the failure of these tumor cells to up-regulate FasL and may explain, in part, the improved prognosis associated with these tumors... - Gastrointestinal polyposes: clinical, pathological and molecular featuresJeremy R Jass
Department of Cellular Pathology, St Mark s Hospital and Imperial College, Watford Road, Harrow, Middlesex HA1 3UJ, UK
Gastroenterol Clin North Am 36:927-46, viii. 2007..One of the most important, but often neglected, of these is hyperplastic polyposis... - Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancerParham Minoo
Department of Pathology, McGill University, Montreal, QC, Canada
Mod Pathol 20:331-8. 2007..These results are suggestive of a tumor suppressor role for Mst1 in human colorectal cancer... - Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002Jeremy R Jass
Cancer Res 62:5988-9; author reply 5989-90. 2002 - Sporadic versus hereditary forms of colorectal cancer with the DNA microsatellite instability phenotype: to 'lump' or 'split'?Jeremy R Jass
Fam Cancer 3:83. 2004 - Fas ligand and tumour counter-attack in colorectal cancer stratified according to microsatellite instability statusJulie M Michael-Robinson
Inflammatory Bowel Disease Laboratory, Royal Brisbane Hospital Foundation Clinical Research Centre, Brisbane, Australia
J Pathol 201:46-54. 2003..004; p = 0.046 respectively). This study therefore suggests that MSS colorectal cancers are killing incoming TILs in an effective tumour counter-attack, but apparently not via membrane-bound FasL... - The impact of microsatellite instability on the molecular phenotype of colorectal tumorsYuriko Mori
Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
Cancer Res 63:4577-82. 2003..Thus, both components 3 and 10 reflected different aspects of MSI and helped to establish principal components analysis as a useful tool to identify and characterize distinct biological features of human malignancy... - Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregationSharlene Gill
British Columbia Cancer Agency, Vancouver, British Columbia, Canada
Clin Cancer Res 11:6466-71. 2005..Rarely, there is selective loss of PMS2 expression. We sought to describe the frequency and clinical correlates of selective loss of expression of PMS2 with the MSI-H tumor phenotype... - Serrated polyps of the large intestine: a morphologic and molecular review of an evolving conceptDale C Snover
Department of Pathology, Fairview Southdale Hospital, Edina, MN 55435, USA, and McGill University, Montreal, Canada
Am J Clin Pathol 124:380-91. 2005.... - What's new in hereditary colorectal cancer?Jeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada
Arch Pathol Lab Med 129:1380-4. 2005..The remainder of the editorial discusses the role of the revised Bethesda guidelines in the diagnosis of hereditary nonpolyposis colorectal cancer and concludes with the recently identified serrated pathway syndrome... - Hyperplastic-like polyps as precursors of microsatellite-unstable colorectal cancerJeremy R Jass
Am J Clin Pathol 119:773-5. 2003 - Overexpression of the receptor for hyaluronic acid mediated motility is an independent adverse prognostic factor in colorectal cancerAlessandro Lugli
Department of Pathology, McGill University, Duff Medical Building, Montreal, QC, Canada
Mod Pathol 19:1302-9. 2006..012) and with complete RHAMM expression in presumed HNPCC (P=0.03). Increasing and complete RHAMM expressions are independent adverse prognostic factors in MMR-proficient CRC and presumed Lynch syndrome... - Differential prognostic significance of morphologic invasive markers in colorectal cancer: tumor budding and cytoplasmic podiaEiji Shinto
Department of Pathology II, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
Dis Colon Rectum 49:1422-30. 2006..In this study, we have investigated the prognostic significance of cytoplasmic podia... - Role of the mitogen-activated protein kinase and phosphoinositide 3-kinase/AKT pathways downstream molecules, phosphorylated extracellular signal-regulated kinase, and phosphorylated AKT in colorectal cancer-a tissue microarray-based approachAlessandro Lugli
Department of Pathology, McGill University, Montreal, Canada H3A 2B4
Hum Pathol 37:1022-31. 2006.... - Heterogeneous microsatellite instability observed within epithelium of ulcerative colitisKazuhide Ozaki
Department of Gastroenterological Surgery and Surgical Oncology, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
Int J Cancer 119:2513-9. 2006..Expression of the MMR proteins was not lost in any of the lesions examined. Microsatellite alterations rather seem to be related to the initiation than to the progression of colitic cancer... - SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancersJune A Chia
The Conjoint Gastroenterology Laboratory, Royal Brisbane and Women s Hospital Foundation Clinical Research Centre and the Queensland Institute of Medical Research, Brisbane, 4029, Australia
BMC Cancer 6:252. 2006..SnoN is an important regulator of the transforming growth factor beta (TGFbeta) signalling pathway and has been shown to exhibit both tumour promotion and suppression activity... - High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopyKevin J Spring
Conjoint Gastroenterology Laboratory, Queensland Institute of Medical Research, Herston, Brisbane, Australia
Gastroenterology 131:1400-7. 2006..They are associated with BRAF mutation, proximal location, female sex, and presence of multiple polyps. These findings emphasize the importance of identifying and removing these lesions for endoscopic prevention of colorectal cancer... - Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancerInti Zlobec
Department of Pathology, McGill University, Montreal, Quebec, Canada
J Clin Pathol 60:1112-6. 2007..Cut-off scores for determining positivity of biomarkers detected by immunohistochemistry are often set arbitrarily and vary between reports... - Hyperplastic polyps and colorectal cancer: is there a link?Jeremy R Jass
Department of Pathology, McGill University, Montreal, Quebec, Canada
Clin Gastroenterol Hepatol 2:1-8. 2004..Screening can then be targeted more selectively toward patients who are at significantly increased risk of malignant transformation of hyperplastic polyps...
Research Grants
- AUSTRALASIAN C0L0RECTAL CANCER FAMILY STUDYJeremy Jass; Fiscal Year: 2002..These characteristics include manageable yet sufficient size, ethnically diverse, highly localised, stable, and with families that are intact and large. ..