J Jane Pillow

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. doi Innovation in surfactant therapy II: surfactant administration by aerosolization
    J Jane Pillow
    Centre for Neonatal Research and Education, University of Western Australia, Perth, WA, Australia
    Neonatology 101:337-44. 2012
  2. ncbi Dependence of intrapulmonary pressure amplitudes on respiratory mechanics during high-frequency oscillatory ventilation in preterm lambs
    J Jane Pillow
    Clinical Sciences Division, Centre for Child Health Research, Subiaco, West Perth, Western Australia
    Pediatr Res 52:538-44. 2002
  3. pmc Lipopolysaccharide-induced weakness in the preterm diaphragm is associated with mitochondrial electron transport chain dysfunction and oxidative stress
    Yong Song
    School of Anatomy, Physiology and Human Biology, The University of Western Australia, Perth, Western Australia, Australia Centre for Neonatal Research and Education, School of Paediatrics and Child Health, The University of Western Australia, Perth, Western Australia, Australia
    PLoS ONE 8:e73457. 2013
  4. doi Pressure- versus volume-limited sustained inflations at resuscitation of premature newborn lambs
    Graeme R Polglase
    Centre for Neonatal Research and Education, School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
    BMC Pediatr 14:43. 2014
  5. doi Which continuous positive airway pressure system is best for the preterm infant with respiratory distress syndrome?
    J Jane Pillow
    The Centre for Neonatal Research and Education, The University of Western Australia, 35 Stirling Highway, Perth, Western Australia, Australia, 6009
    Clin Perinatol 39:483-96. 2012
  6. doi Oxygen, temperature and humidity of inspired gases and their influences on airway and lung tissue in near-term lambs
    J Jane Pillow
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Perth 6008, Australia
    Intensive Care Med 35:2157-63. 2009
  7. pmc Bubble continuous positive airway pressure enhances lung volume and gas exchange in preterm lambs
    J Jane Pillow
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Respir Crit Care Med 176:63-9. 2007
  8. doi Variable ventilation improves ventilation and lung compliance in preterm lambs
    J Jane Pillow
    School of Women s and Infants Health, M550, University of Western Australia, 374 Bagot Rd, Subiaco, Perth, WA 6008, Australia
    Intensive Care Med 37:1352-9. 2011
  9. pmc Positive end-expiratory pressure and tidal volume during initial ventilation of preterm lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia, 6009, Australia
    Pediatr Res 64:517-22. 2008
  10. doi Ventilation-mediated injury after preterm delivery of Ureaplasma parvum colonized fetal lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia 6009, Australia
    Pediatr Res 67:630-5. 2010

Detail Information

Publications37

  1. doi Innovation in surfactant therapy II: surfactant administration by aerosolization
    J Jane Pillow
    Centre for Neonatal Research and Education, University of Western Australia, Perth, WA, Australia
    Neonatology 101:337-44. 2012
    ..Further work is also required to determine the optimum delivery route (mask, intranasal prong, nasopharyngeal or laryngeal), dosing amount and redosing interval...
  2. ncbi Dependence of intrapulmonary pressure amplitudes on respiratory mechanics during high-frequency oscillatory ventilation in preterm lambs
    J Jane Pillow
    Clinical Sciences Division, Centre for Child Health Research, Subiaco, West Perth, Western Australia
    Pediatr Res 52:538-44. 2002
    ....
  3. pmc Lipopolysaccharide-induced weakness in the preterm diaphragm is associated with mitochondrial electron transport chain dysfunction and oxidative stress
    Yong Song
    School of Anatomy, Physiology and Human Biology, The University of Western Australia, Perth, Western Australia, Australia Centre for Neonatal Research and Education, School of Paediatrics and Child Health, The University of Western Australia, Perth, Western Australia, Australia
    PLoS ONE 8:e73457. 2013
    ....
  4. doi Pressure- versus volume-limited sustained inflations at resuscitation of premature newborn lambs
    Graeme R Polglase
    Centre for Neonatal Research and Education, School of Paediatrics and Child Health, University of Western Australia, Perth, Australia
    BMC Pediatr 14:43. 2014
    ..We investigated whether a volume-limited SI improved the establishment of FRC and ventilation homogeneity and reduced lung inflammation/injury compared to a pressure-limited SI...
  5. doi Which continuous positive airway pressure system is best for the preterm infant with respiratory distress syndrome?
    J Jane Pillow
    The Centre for Neonatal Research and Education, The University of Western Australia, 35 Stirling Highway, Perth, Western Australia, Australia, 6009
    Clin Perinatol 39:483-96. 2012
    ....
  6. doi Oxygen, temperature and humidity of inspired gases and their influences on airway and lung tissue in near-term lambs
    J Jane Pillow
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Perth 6008, Australia
    Intensive Care Med 35:2157-63. 2009
    ..We hypothesized that oxygen content and humidity of inspired air would influence markers of pulmonary inflammation in ventilated lambs...
  7. pmc Bubble continuous positive airway pressure enhances lung volume and gas exchange in preterm lambs
    J Jane Pillow
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Am J Respir Crit Care Med 176:63-9. 2007
    ..The technique used to provide continuous positive airway pressure (CPAP) to the newborn may influence lung function and breathing efficiency...
  8. doi Variable ventilation improves ventilation and lung compliance in preterm lambs
    J Jane Pillow
    School of Women s and Infants Health, M550, University of Western Australia, 374 Bagot Rd, Subiaco, Perth, WA 6008, Australia
    Intensive Care Med 37:1352-9. 2011
    ..We assessed the physiological consequences of variable ventilation in the immature lung...
  9. pmc Positive end-expiratory pressure and tidal volume during initial ventilation of preterm lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia, 6009, Australia
    Pediatr Res 64:517-22. 2008
    ..Ventilation resulted in localization of IL-6 to the small airways. Initial ventilation of preterm lambs with PEEP and/or VT of 8 mL/kg did not prevent an inflammatory injury to the lung...
  10. doi Ventilation-mediated injury after preterm delivery of Ureaplasma parvum colonized fetal lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Subiaco, Western Australia 6009, Australia
    Pediatr Res 67:630-5. 2010
    ..Antenatal colonization with UP did not change lung function or modulate the lung injury and inflammation caused by high VT ventilation...
  11. doi Cardiopulmonary haemodynamics in lambs during induced capillary leakage immediately after preterm birth
    Graeme R Polglase
    Women s and Infants Health, University of Western Australia, Crawley, WA, Australia
    Clin Exp Pharmacol Physiol 38:222-8. 2011
    ..Capillary leakage might contribute to postnatal cardiopulmonary failure in preterm infants...
  12. pmc Pulmonary vascular and alveolar development in preterm lambs chronically colonized with Ureaplasma parvum
    Graeme R Polglase
    The University of Western Australia, Perth, Australia
    Am J Physiol Lung Cell Mol Physiol 299:L232-41. 2010
    ..We conclude that chronic exposure to U. parvum does not cause sustained effects on air space or vascular development in premature lambs...
  13. doi Cardiovascular and pulmonary consequences of airway recruitment in preterm lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, M094, 35 Stirling Highway, Crawley, 6009, Western Australia, Australia
    J Appl Physiol (1985) 106:1347-55. 2009
    ..These changes are likely due to the concomitant increase in downstream pulmonary vascular resistance and increased cardiovascular constraint induced by PEEP...
  14. doi Lung and systemic inflammation in preterm lambs on continuous positive airway pressure or conventional ventilation
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia 6009, Australia
    Pediatr Res 65:67-71. 2009
    ..Blood neutrophils decreased similarly after LPS in CPAP and CMV groups. Cytokine markers of lung injury or the systemic response to intratracheal LPS were not decreased by CPAP relative to CMV, in preterm lambs..
  15. ncbi Variability in preterm lamb lung mechanics after intra-amniotic endotoxin is associated with changes in surfactant pool size and morphometry
    J Jane Pillow
    Centre for Child Health Research, The University of Western Australia, Perth, Australia
    Am J Physiol Lung Cell Mol Physiol 287:L992-8. 2004
    ..Despite the complex cascade of events initiated by antenatal endotoxin exposure, variability in lung tissue mechanics is associated primarily with changes in alveolar Sat PC pool and lung morphology...
  16. doi Fetal responses to lipopolysaccharide-induced chorioamnionitis alter immune and airway responses in 7-week-old sheep
    Andrea J X Lee
    School of Women s and Infant s Health, The University of Western Australia, Perth, Australia
    Am J Obstet Gynecol 204:364.e17-24. 2011
    ..We hypothesized that fetal innate immune responses to lipopolysaccharide-induced chorioamnionitis would alter postnatal systemic immune and airway responsiveness...
  17. doi Intrauterine inflammation causes pulmonary hypertension and cardiovascular sequelae in preterm lambs
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Crawley, Western Australia, Australia
    J Appl Physiol (1985) 108:1757-65. 2010
    ....
  18. doi Lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age
    Sven M Schulzke
    School of Women s and Infant s Health, University of Western Australia, Perth, Australia
    J Pediatr 156:542-9.e2. 2010
    ....
  19. doi High positive end-expiratory pressure during high-frequency jet ventilation improves oxygenation and ventilation in preterm lambs
    Gabrielle C Musk
    School of Women s and Infants Health, University of Western Australia, Perth, Western Australia 6009, Australia
    Pediatr Res 69:319-24. 2011
    ..Inflammatory markers were lower in the PEEPadj group. Adjusted PEEP during HFJV improves oxygenation and lung compliance and reduces ventilator requirements despite reducing pulmonary perfusion...
  20. doi Differential effect of recruitment maneuvres on pulmonary blood flow and oxygenation during HFOV in preterm lambs
    Graeme R Polglase
    School of Women s and Infants Health, M094 The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, 6009, Australia
    J Appl Physiol (1985) 105:603-10. 2008
    ..Thus the choice of volume recruitment maneuvre influences the magnitude of change in OI and PBF that occurs during HFOV. Despite significantly improving OI, the ramp recruitment approach causes sustained changes in PBF...
  21. doi Feasibility and short-term effects of biphasic positive airway pressure versus assist-control ventilation in preterm lambs
    Sven M Schulzke
    School of Women s and Infant s Health, University of Western Australia, Crawley, Western Australia 6009, Australia
    Pediatr Res 66:665-70. 2009
    ..In unsedated preterm lambs, BiLevel ventilation provides gas exchange equivalent to A-C ventilation and potentially results in reduced lung injury...
  22. ncbi Monitoring of lung volume recruitment and derecruitment using oscillatory mechanics during high-frequency oscillatory ventilation in the preterm lamb
    J Jane Pillow
    Clinical Sciences Division, Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Australia
    Pediatr Crit Care Med 5:172-80. 2004
    ....
  23. ncbi High-frequency oscillatory ventilation: mechanisms of gas exchange and lung mechanics
    J Jane Pillow
    Institute for Child Health Research, and the School of Women s and Infants Health, University of Western Australia, Subiaco, Perth, Australia
    Crit Care Med 33:S135-41. 2005
    ....
  24. ncbi Bubble CPAP: is the noise important? An in vitro study
    J Jane Pillow
    Centre for Child Health Research, The University of Western Australia, Perth, 6008 Western Australia, Australia
    Pediatr Res 57:826-30. 2005
    ..Lung mechanics and applied flow influence the magnitude of the noise superimposed on the transmitted pressure waveform and may influence lung volume recruitment in bubble CPAP...
  25. ncbi Lung function tests in neonates and infants with chronic lung disease: global and regional ventilation inhomogeneity
    J Jane Pillow
    Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia, Australia
    Pediatr Pulmonol 41:105-21. 2006
    ..For both techniques, there is an urgent need to establish guidelines regarding data collection, analysis, and interpretation in infants both with and without CLDI...
  26. ncbi Partitioning of airway and parenchymal mechanics in unsedated newborn infants
    J Jane Pillow
    Portex Unit, Respiratory Physiology, Institue of Child Health, and Neonatal Unit, University College London Hospital, UK
    Pediatr Res 58:1210-5. 2005
    ..Measurements of lung function are feasible in the unsedated newborn infant using low-frequency forced oscillations and confirm the important contribution of tissue resistance to lung mechanics in the developing lung...
  27. pmc Ontogeny of proteolytic signaling and antioxidant capacity in fetal and neonatal diaphragm
    Yong Song
    Centre for Neonatal Research and Education, The University of Western Australia, Crawley 6009, Western Australia, Australia
    Anat Rec (Hoboken) 295:864-71. 2012
    ..002). The proteolytic signaling and antioxidant capacity patterns reflect the adaptive process to metabolic change and muscle maturity with development...
  28. doi Impact of conventional breath inspiratory time during high-frequency jet ventilation in preterm lambs
    Gabrielle C Musk
    School of Women s and Infants Health, The University of Western Australia, Crawley, WA, Australia
    Neonatology 101:267-73. 2012
    ..Conventional mechanical ventilator (CMV) breaths during high-frequency jet ventilation (HFJV) are advocated to recruit and stabilize alveoli...
  29. doi Variable ventilation enhances ventilation without exacerbating injury in preterm lambs with respiratory distress syndrome
    Clare A Berry
    Centre for Neonatal Research and Education, School of Women s and Infants Health, University of Western Australia, Perth, Australia
    Pediatr Res 72:384-92. 2012
    ..We hypothesized that if V(T) was adjusted to target permissive hypercarbia, VV would result in more efficient gas exchange without increasing inflammatory and injurious responses in the lung...
  30. ncbi Lung-function tests in neonates and infants with chronic lung disease: tidal breathing and respiratory control
    David N Baldwin
    Centre for Child Health Research and Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia, Australia
    Pediatr Pulmonol 41:391-419. 2006
    ..Clinical observations are supported by formal comparison of tidal breathing parameters and control of breathing indices in the research setting...
  31. doi The management of evolving bronchopulmonary dysplasia
    Sven M Schulzke
    School of Women s and Infants Health, The University of Western Australia, Perth, Australia
    Paediatr Respir Rev 11:143-8. 2010
    ..Several ongoing randomised trials are evaluating optimal oxygen saturation targets in preterm infants. The most beneficial respiratory support strategy to minimise lung injury remains unclear and requires further investigation...
  32. pmc Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep
    Noah H Hillman
    Cincinnati Children s Hospital Medical Center, Division of Pulmonary Biology, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Am J Respir Crit Care Med 176:575-81. 2007
    ..Premature infants are exposed to potentially injurious ventilation in the delivery room. Assessments of lung injury are confounded by effects of subsequent ventilatory support...
  33. ncbi Lung function tests in neonates and infants with chronic lung disease of infancy: functional residual capacity
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 41:1-22. 2006
    ..Although lung volume measurements in extremely preterm infants were described in a research environment, resolution of several issues is required before such investigations can be translated into routine clinical monitoring...
  34. ncbi Lung function tests in neonates and infants with chronic lung disease: lung and chest-wall mechanics
    Monika Gappa
    Department of Pediatric Pulmonology and Neonatology, Medizinische Hochschule Hannover, Hannover, Germany
    Pediatr Pulmonol 41:291-317. 2006
    ..New methods such as the low-frequency forced oscillation technique, which differentiate the tissue and airway components of respiratory mechanics, are likely to require further development before they can be of clinical significance...
  35. ncbi Progressive decline in plethysmographic lung volumes in infants: physiology or technology?
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Am J Respir Crit Care Med 168:1003-9. 2003
    ..These findings emphasize the need to establish reference data for lung function tests in infants that are appropriate for the equipment and protocols in current use...
  36. ncbi An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children
    Nicole Beydon
    Am J Respir Crit Care Med 175:1304-45. 2007
  37. ncbi Lung function testing in acute neonatal respiratory disorders and chronic lung disease of infancy: a review series
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 40:467-70. 2005