Chris Jackson

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi request reprint Selective matrix metalloproteinase (MMP) inhibition in rheumatoid arthritis--targetting gelatinase A activation
    C Jackson
    Sutton Arthritis Research Laboratory, Royal North Shore Hospital, St Leonards, NSW, Australia
    Inflamm Res 50:183-6. 2001
  2. ncbi request reprint Matrix metalloproteinases and angiogenesis
    Chris Jackson
    Sutton Arthritis Research Laboratory, Royal North Shore Hospital, St Leonards, New South Wales, Australia
    Curr Opin Nephrol Hypertens 11:295-9. 2002
  3. ncbi request reprint Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing
    Christopher J Jackson
    The Sutton Arthritis Research Laboratories, Institute of Bone and Joint Research, University of Sydney, Sydney, New South Wales, Australia
    Wound Repair Regen 13:284-94. 2005
  4. ncbi request reprint New therapeutic applications for the anticoagulant, activated protein C
    Chris Jackson
    Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, University of Sydney at Royal North Shore Hospital, 2065 Australia
    Expert Opin Biol Ther 8:1109-22. 2008
  5. doi request reprint Activated protein C--an anticoagulant that does more than stop clots
    Christopher J Jackson
    Sutton Arthritis Research Laboratories, Department of Rheumatology, Institute of Bone and Joint Research, Level 1, Block 4, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065 Australia
    Int J Biochem Cell Biol 40:2692-7. 2008
  6. doi request reprint Treatment of chronic leg ulcers with topical activated protein C
    Kaley Whitmont
    Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia
    Arch Dermatol 144:1479-83. 2008
  7. ncbi request reprint Activated protein C stimulates proliferation, migration and wound closure, inhibits apoptosis and upregulates MMP-2 activity in cultured human keratinocytes
    Meilang Xue
    Sutton Arthritis Research Laboratory, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Exp Cell Res 299:119-27. 2004
  8. ncbi request reprint Regional cardiac dysfunction is associated with specific alterations in inflammatory cytokines and matrix metalloproteinases after acute myocardial infarction in sheep
    Gabrielle Gallagher
    Cardiac Technology Centre, Dept of Cardiology and Kolling Institute of Medical Research, Block 4, Level 3, University of Sydney at Royal North Shore Hospital St Leonards, NSW, Australia
    Basic Res Cardiol 102:63-72. 2007
  9. ncbi request reprint Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes
    Meilang Xue
    Sutton Research Laboratories, Level 1, Block 4, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Int J Biochem Cell Biol 37:2406-16. 2005
  10. doi request reprint Toxic epidermal necrolysis: review of pathogenesis and management
    Andrew Downey
    The University of Sydney, Sydney, New South Wales, Australia
    J Am Acad Dermatol 66:995-1003. 2012

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Selective matrix metalloproteinase (MMP) inhibition in rheumatoid arthritis--targetting gelatinase A activation
    C Jackson
    Sutton Arthritis Research Laboratory, Royal North Shore Hospital, St Leonards, NSW, Australia
    Inflamm Res 50:183-6. 2001
    ....
  2. ncbi request reprint Matrix metalloproteinases and angiogenesis
    Chris Jackson
    Sutton Arthritis Research Laboratory, Royal North Shore Hospital, St Leonards, New South Wales, Australia
    Curr Opin Nephrol Hypertens 11:295-9. 2002
    ..These multiple regulatory pathways permit fine control over cell invasion during angiogenesis and provide new, precise strategies for targeting abnormal angiogenesis, through control of matrix metalloproteinase activity...
  3. ncbi request reprint Activated protein C prevents inflammation yet stimulates angiogenesis to promote cutaneous wound healing
    Christopher J Jackson
    The Sutton Arthritis Research Laboratories, Institute of Bone and Joint Research, University of Sydney, Sydney, New South Wales, Australia
    Wound Repair Regen 13:284-94. 2005
    ..These unique properties of APC make it an attractive therapeutic agent to promote the healing of chronic wounds...
  4. ncbi request reprint New therapeutic applications for the anticoagulant, activated protein C
    Chris Jackson
    Institute of Bone and Joint Research, Kolling Institute, Sutton Arthritis Research Laboratories, Department of Rheumatology, University of Sydney at Royal North Shore Hospital, 2065 Australia
    Expert Opin Biol Ther 8:1109-22. 2008
    ..Originally thought to be synthesised exclusively by the liver, recent reports have shown that PC is also produced by endothelial cells, smooth muscle cells, keratinocytes and some leukocytes...
  5. doi request reprint Activated protein C--an anticoagulant that does more than stop clots
    Christopher J Jackson
    Sutton Arthritis Research Laboratories, Department of Rheumatology, Institute of Bone and Joint Research, Level 1, Block 4, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065 Australia
    Int J Biochem Cell Biol 40:2692-7. 2008
    ..The future pharmacologic use of APC holds remarkable promise...
  6. doi request reprint Treatment of chronic leg ulcers with topical activated protein C
    Kaley Whitmont
    Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia
    Arch Dermatol 144:1479-83. 2008
    ..We report 4 cases of nonhealing lower limb skin ulcers that were treated with activated protein C...
  7. ncbi request reprint Activated protein C stimulates proliferation, migration and wound closure, inhibits apoptosis and upregulates MMP-2 activity in cultured human keratinocytes
    Meilang Xue
    Sutton Arthritis Research Laboratory, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Exp Cell Res 299:119-27. 2004
    ..This regulatory activity implicates APC as having potential to promote re-epithelialisation during wound healing...
  8. ncbi request reprint Regional cardiac dysfunction is associated with specific alterations in inflammatory cytokines and matrix metalloproteinases after acute myocardial infarction in sheep
    Gabrielle Gallagher
    Cardiac Technology Centre, Dept of Cardiology and Kolling Institute of Medical Research, Block 4, Level 3, University of Sydney at Royal North Shore Hospital St Leonards, NSW, Australia
    Basic Res Cardiol 102:63-72. 2007
    ..Therapies for LV remodeling from the time of reperfusion may benefit from further understanding this portfolio of acute alterations...
  9. ncbi request reprint Leukocyte matrix metalloproteinase-9 is elevated and contributes to lymphocyte activation in type I diabetes
    Meilang Xue
    Sutton Research Laboratories, Level 1, Block 4, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Int J Biochem Cell Biol 37:2406-16. 2005
    ..These data suggest that elevated leukocyte MMP-9 may contribute to the pathogenesis of type I diabetes and its associated complications...
  10. doi request reprint Toxic epidermal necrolysis: review of pathogenesis and management
    Andrew Downey
    The University of Sydney, Sydney, New South Wales, Australia
    J Am Acad Dermatol 66:995-1003. 2012
    ..The value of current therapies, such as intravenous immunoglobulin and corticosteroids, remains under evaluation...