J Hung

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial infarction
    J Hung
    Department of Medicine, University of Western Australia, Perth, Australia
    Heart 78:346-52. 1997
  2. ncbi Aspirin for cardiovascular disease prevention
    Joseph Hung
    School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, WA
    Med J Aust 179:147-52. 2003
  3. ncbi Folate and vitamin B-12 and risk of fatal cardiovascular disease: cohort study from Busselton, Western Australia
    Joseph Hung
    Department of Cardiology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands WA 6009, Australia
    BMJ 326:131. 2003
  4. ncbi C-reactive protein and interleukin-18 levels in relation to coronary heart disease: prospective cohort study from Busselton Western Australia
    Joseph Hung
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Nedlands, Western Australia, Australia
    Heart Lung Circ 17:90-5. 2008
  5. ncbi Prevalence and risk factor correlates of elevated C-reactive protein in an adult Australian population
    Joseph Hung
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Perth, Western Australia
    Am J Cardiol 101:193-8. 2008
  6. ncbi Circulating adiponectin levels associate with inflammatory markers, insulin resistance and metabolic syndrome independent of obesity
    J Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, Perth, Western Australia, Australia
    Int J Obes (Lond) 32:772-9. 2008
  7. ncbi Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population
    J Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, Australia 6009
    Arterioscler Thromb Vasc Biol 19:1969-74. 1999
  8. ncbi Treatment disparities and effect on late mortality in patients with diabetes presenting with acute myocardial infarction: observations from the ACACIA registry
    Joseph Hung
    University of Western Australia School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, Perth, WA, Australia
    Med J Aust 191:539-43. 2009
  9. ncbi Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance
    Joseph Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, and School of Medicine and Pharmacology, University of Western Australia, Nedlands, Perth
    Arterioscler Thromb Vasc Biol 25:1268-73. 2005
  10. ncbi Polymorphisms in the angiotensinogen gene are associated with carotid intimal-medial thickening in females from a community-based population
    C M Chapman
    Clinical Biochemistry, PathCentre, Locked Bag 2009, 6909, Nedlands, Australia
    Atherosclerosis 159:209-17. 2001

Collaborators

Detail Information

Publications52

  1. ncbi Dipyridamole thallium-201 scintigraphy for early risk stratification of patients after uncomplicated myocardial infarction
    J Hung
    Department of Medicine, University of Western Australia, Perth, Australia
    Heart 78:346-52. 1997
    ..To determine the safety and prognostic value of dipyridamole thallium-201 scintigraphy performed in patients within three to five days of acute myocardial infarction, including those receiving thrombolytic treatment...
  2. ncbi Aspirin for cardiovascular disease prevention
    Joseph Hung
    School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, WA
    Med J Aust 179:147-52. 2003
    ..In general, the risk of bleeding increases with increasing dose of aspirin and when it is used in combination with non-steroidal anti-inflammatory drugs or oral anticoagulants...
  3. ncbi Folate and vitamin B-12 and risk of fatal cardiovascular disease: cohort study from Busselton, Western Australia
    Joseph Hung
    Department of Cardiology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands WA 6009, Australia
    BMJ 326:131. 2003
    ..To test the hypothesis that the incidence of fatal coronary heart disease and cardiovascular disease in a general population is related to serum and red cell folate and vitamin B-12 concentrations...
  4. ncbi C-reactive protein and interleukin-18 levels in relation to coronary heart disease: prospective cohort study from Busselton Western Australia
    Joseph Hung
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Nedlands, Western Australia, Australia
    Heart Lung Circ 17:90-5. 2008
    ..We investigated the relationship between C-reactive protein (CRP) and interleukin-18 (IL-18) levels and risk of CHD in men and women without initial cardiovascular disease...
  5. ncbi Prevalence and risk factor correlates of elevated C-reactive protein in an adult Australian population
    Joseph Hung
    School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Perth, Western Australia
    Am J Cardiol 101:193-8. 2008
    ..Because increased CRP was largely attributable to conventional coronary heart disease risk factors, measurement of CRP may have limited utility for risk screening and primary prevention...
  6. ncbi Circulating adiponectin levels associate with inflammatory markers, insulin resistance and metabolic syndrome independent of obesity
    J Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, Perth, Western Australia, Australia
    Int J Obes (Lond) 32:772-9. 2008
    ..We examined whether the relationship between adiponectin and inflammatory markers, insulin resistance and MetS was independent of obesity...
  7. ncbi Angiotensin-converting enzyme gene polymorphism and carotid wall thickening in a community population
    J Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, Australia 6009
    Arterioscler Thromb Vasc Biol 19:1969-74. 1999
    ..We conclude that, although the ACE I/D polymorphism is strongly related to ACE activity, it is not a risk predictor of carotid wall thickening or focal plaque formation when examined in a large randomly selected community population...
  8. ncbi Treatment disparities and effect on late mortality in patients with diabetes presenting with acute myocardial infarction: observations from the ACACIA registry
    Joseph Hung
    University of Western Australia School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, Perth, WA, Australia
    Med J Aust 191:539-43. 2009
    ....
  9. ncbi Elevated interleukin-18 levels are associated with the metabolic syndrome independent of obesity and insulin resistance
    Joseph Hung
    Sir Charles Gairdner Hospital Campus of the Heart Research Institute of Western Australia, and School of Medicine and Pharmacology, University of Western Australia, Nedlands, Perth
    Arterioscler Thromb Vasc Biol 25:1268-73. 2005
    ..We sought to determine whether an elevated IL-18 concentration was a risk predictor for metabolic syndrome in a community population independent of obesity and hyperinsulinemia...
  10. ncbi Polymorphisms in the angiotensinogen gene are associated with carotid intimal-medial thickening in females from a community-based population
    C M Chapman
    Clinical Biochemistry, PathCentre, Locked Bag 2009, 6909, Nedlands, Australia
    Atherosclerosis 159:209-17. 2001
    ..We investigated the association of polymorphisms in the angiotensinogen (AGT) and angiotensin II receptor type 1 (AGTR1) genes with increased intima-media thickness (IMT) and the presence of plaques in carotid arteries...
  11. ncbi Interleukin-18 levels are not associated with subclinical carotid atherosclerosis in a community population. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
    Caroline M L Chapman
    Clinical Biochemistry, PathWest, QEII Medical Centre, Perth, WA, Australia
    Atherosclerosis 189:414-9. 2006
    ..05). In a cross-sectional community population, IL-18 levels were related to traditional risk factors and inflammatory markers but were not independently associated with subclinical carotid atherosclerosis...
  12. ncbi Association of an allelic variant of interleukin-6 with subclinical carotid atherosclerosis in an Australian community population
    Caroline M L Chapman
    Clinical Biochemistry, Western Australian Centre for Pathology and Medical Research, Western Australia, Perth, Australia
    Eur Heart J 24:1494-9. 2003
    ..We examined the association of a common functional variant in the IL-6 gene with carotid intimal-medial wall thickness (IMT) and the presence of plaques in a randomly selected, cross-sectional Australian population...
  13. ncbi A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity
    M M Swarbrick
    Department of Clinical Biochemistry, PathCentre, Nedlands, Western Australia 6009, Australia
    Eur J Endocrinol 144:277-82. 2001
    ..The aim of this investigation was to determine whether a PPAR gamma 2 Pro12Ala polymorphism was associated with cardiovascular risk factors (obesity, blood pressure, diabetes and blood lipids) in Western Australian Caucasians (n=663)...
  14. ncbi The C-480T hepatic lipase polymorphism is associated with HDL-C but not with risk of coronary heart disease
    P A McCaskie
    Laboratory for Genetic Epidemiology, Western Australian Institute for Medical Research, Centre for Medical Research, University of Western Australia, Nedlands, Perth, Western Australia
    Clin Genet 70:114-21. 2006
    ..19-0.78, p = 0.008). These findings replicate those of previous studies in three independent populations and suggest that the genetic determinants of CHD are complex and cannot be entirely explained through intermediate phenotypes...
  15. ncbi Antioxidant vitamins and the risk of carotid atherosclerosis. The Perth Carotid Ultrasound Disease Assessment study (CUDAS)
    B M McQuillan
    Gairdner Campus of the Heart Research Institute of Western Australia, Western, Nedlands, Perth, Australia
    J Am Coll Cardiol 38:1788-94. 2001
    ..No benefit was demonstrated for supplemental antioxidant vitamin use...
  16. ncbi The apolipoprotein AII rs5082 variant is associated with reduced risk of coronary artery disease in an Australian male population
    Jing Xiao
    Western Australian Institute for Medical Research, Centre for Medical Research, University of Western Australia, Australia
    Atherosclerosis 199:333-9. 2008
    ..We conclude that the APOAII rs5082 polymorphism appears to be cardioprotective in this representative Caucasian Australian population...
  17. ncbi Prior calcium channel blockade and short-term survival following acute myocardial infarction
    R W Parsons
    Department of Public Health, University of Western Australia, Perth, Australia
    Cardiovasc Drugs Ther 15:487-92. 2001
    ....
  18. ncbi Serum ferritin and C282Y mutation of the hemochromatosis gene as predictors of asymptomatic carotid atherosclerosis in a community population
    E Rossi
    Department of Clinical Biochemistry, PathCentre, Queen Elizabeth II Medical Centre, Nedlands, Western Australia
    Stroke 31:3015-20. 2000
    ..The purpose of the study was to test whether either is a risk predictor for asymptomatic carotid atherosclerosis...
  19. ncbi Stromelysin-1 (MMP-3) gene 5A/6A promoter polymorphism is associated with blood pressure in a community population
    John P Beilby
    Clinical Biochemistry, Western Australian Centre for Pathology and Medical Research PathCentre and School of Surgery and Pathology, University of Western Australia, Perth, Western Australia
    J Hypertens 23:537-42. 2005
    ..Stromelysin-1 gene expression is partly regulated by a common polymorphism in the promoter region of either five or six consecutive adenosine bases (5A/6A)...
  20. ncbi Investigating the association between K198N coding polymorphism in EDN1 and hypertension, lipoprotein levels, the metabolic syndrome and cardiovascular disease
    Steven Wiltshire
    Western Australian Institute for Medical Research and UWA Centre for Medical Research, University of Western Australia, Perth, Australia
    Hum Genet 123:307-13. 2008
    ..In conclusion, we found no robust evidence for the associations between K198N and hypertension, systolic blood pressure or HDL levels seen in previous studies...
  21. ncbi Biological variability and reference intervals for total plasma homocysteine
    E Rossi
    Biochemistry Section, PathCentre, QE II Medical Centre, Nedlands, Australia
    Ann Clin Biochem 36:56-61. 1999
    ..An 'ideal' homocysteine reference range, based on targeting those subjects who are likely to be folate replete, is preferable to the population-based range using the central 0.95 interval...
  22. ncbi Impact of new biomarkers of myocardial damage on trends in myocardial infarction hospital admission rates from population-based administrative data
    F M Sanfilippo
    School of Population Health, University of Western Australia, Crawley, Western Australia, Australia
    Am J Epidemiol 168:225-33. 2008
    ..Similarly constructed logistic regression trend models found no significant effect of troponin testing on trends in 28-day case-fatality...
  23. ncbi Long term survival after evidence based treatment of acute myocardial infarction and revascularisation: follow-up of population based Perth MONICA cohort, 1984-2005
    Tom Briffa
    School of Population Health M431, University of Western Australia, Crawley, Western Australia 6009
    BMJ 338:b36. 2009
    ..To examine trends in long term survival in patients alive 28 days after myocardial infarction and the impact of evidence based medical treatments and coronary revascularisation during or near the event...
  24. ncbi Serum alanine aminotransferase, metabolic syndrome, and cardiovascular disease in an Australian population
    John K Olynyk
    School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia
    Am J Gastroenterol 104:1715-22. 2009
    ..The aim of this study was to determine whether elevated ALT concentrations are predictive of Met S or cardiovascular events...
  25. ncbi Folic acid does not improve endothelial function in healthy hyperhomocysteinaemic subjects
    Richard J Woodman
    School of Medicine and Pharmacology, University of Western Australia, West Australian Institute of Medical Research, GPO Box X2213, Perth, WA 6847, Australia
    Clin Sci (Lond) 106:353-8. 2004
    ..7 +/- 0.5%; P = 0.17 compared with placebo). In healthy subjects with hyperhomocysteinaemia, but without additional cardiovascular risk, endothelial function is unimpaired and folic acid supplementation has no additional effect...
  26. ncbi Are the associations between diet and C-reactive protein independent of obesity?
    Siobhan Hickling
    School of Population Health, The University of Western Australia, Crawley 6009, Australia
    Prev Med 47:71-6. 2008
    ..To determine the relative magnitude of the effect of dietary factors on circulating C-reactive protein (CRP) levels, controlling for BMI...
  27. ncbi The effect of evidence-based medication use on long-term survival in patients hospitalised for heart failure in Western Australia
    Tiew Hwa Katherine Teng
    School of Population Health, University of Western Australia, Perth, WA
    Med J Aust 192:306-10. 2010
    ..To examine trends and predictors of prescription medications on discharge after first (index) hospitalisation for heart failure (HF), and the effect on all-cause mortality of evidence-based therapy...
  28. ncbi 15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intima-media thickness
    Pamela A McCaskie
    Laboratory for Genetic Epidemiology, Western Australian Institute for Medical Research, UWA Centre for Medical Research, University of Western Australia, Perth, WA, Australia
    Hum Genet 123:445-53. 2008
    ..This study is novel as it is the first to examine the association between 15-lipoxygenase polymorphisms and atherosclerotic indicators. These findings suggest a possible role of ALOX15 polymorphisms in focal plaque formation...
  29. ncbi Discordant age and sex-specific trends in the incidence of a first coronary heart disease event in Western Australia from 1996 to 2007
    Tom Briffa
    School of Population Health, University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia
    Heart 97:400-4. 2011
    ..To determine age- and sex-specific population trends in fatal and non-fatal first coronary heart disease (CHD) events in Western Australia from 1996 to 2007...
  30. ncbi Heart failure: incidence, case fatality, and hospitalization rates in Western Australia between 1990 and 2005
    Tiew Hwa Katherine Teng
    School of Population Health, University of Western Australia, Perth, Western Australia
    Circ Heart Fail 3:236-43. 2010
    ..We examined trends in incidence of first-ever (index) hospitalization for heart failure (HF), hospitalization rates, and 30-day and 1-year all-cause mortality subsequent to index hospitalization for HF...
  31. ncbi A validation study: how effective is the Hospital Morbidity Data as a surveillance tool for heart failure in Western Australia?
    Tiew Hwa Katherine Teng
    School of Population Heath, University of Western Australia, Crawley, Western Australia, Australia
    Aust N Z J Public Health 32:405-7. 2008
    ..To determine the accuracy of the hospital discharge coding of heart failure (HF) in the Western Australian (WA) Hospital Morbidity Data (HMD)...
  32. ncbi Utility of the metabolic syndrome and its components in the prediction of incident cardiovascular disease: a prospective cohort study
    Matthew W Knuiman
    School of Population Health, University of Western Australia, Nedlands, Western Australia, Australia
    Eur J Cardiovasc Prev Rehabil 16:235-41. 2009
    ..To investigate the prognostic importance of the metabolic syndrome (MetS) on incident cardiovascular disease (CVD)...
  33. ncbi Association of Interleukin-1 gene polymorphisms with central obesity and metabolic syndrome in a coronary heart disease population
    Kim W Carter
    Western Australian Institute for Medical Research and UWA Centre for Medical Research, University of Western Australia, Perth, WA, Australia
    Hum Genet 124:199-206. 2008
    ....
  34. ncbi Thermoregulatory responses in post-coronary artery bypass surgery and healthy males during moderate exercise in warm and cool environments
    Jennifer Walsh
    Department of Human Movement and Exercise Science, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009
    J Cardiopulm Rehabil 22:31-7. 2002
    ....
  35. ncbi Monocyte count, but not C-reactive protein or interleukin-6, is an independent risk marker for subclinical carotid atherosclerosis
    Caroline M L Chapman
    Clinical Biochemistry, Western Australian Centre for Pathology and Medical Research, Perth, Western Australia
    Stroke 35:1619-24. 2004
    ..Monocyte count may represent an inexpensive, easy-to-measure risk marker for subclinical carotid atherosclerosis...
  36. ncbi Promoter polymorphism of the gene for CD14 receptor is not associated with sub-clinical carotid atherosclerosis in a community population
    Joseph Hung
    Sir Charles Gairdner Hospital Unit of the School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia
    Eur J Cardiovasc Prev Rehabil 11:344-9. 2004
    ..We examined if this polymorphism was associated with sub-clinical carotid atherosclerosis in a community population...
  37. ncbi Effects of a multidisciplinary, post-discharge continuance of care intervention on quality of life, discharge satisfaction, and hospital length of stay: a randomized controlled trial
    David B Preen
    The University of Western Australia, School of Population Health, Perth, Western Australia, Australia
    Int J Qual Health Care 17:43-51. 2005
    ....
  38. ncbi Impact of voluntary folate fortification on plasma homocysteine and serum folate in Australia from 1995 to 2001: a population based cohort study
    Siobhan Hickling
    School of Population Health, University of Western Australia, Australia
    J Epidemiol Community Health 59:371-6. 2005
    ..To investigate the effect of the voluntary folate fortification policy in Australia on serum folate and total plasma homocysteine (tHcy) concentrations...
  39. ncbi A rapid dietary assessment tool to determine intake of folate was developed and validated
    Siobhan Hickling
    School of Population Health, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    J Clin Epidemiol 58:802-8. 2005
    ..We developed and tested the reliability and validity of two prototypes of a rapid dietary assessment tool (a folate intake tool, FIT) to determine dietary intake of folate...
  40. ncbi Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease
    Pamela A McCaskie
    Laboratory for Genetic Epidemiology, Western Australian Institute for Medical Research, UWA Centre for Medical Research, University of Western Australia, Nedlands, WA, 6009, Australia
    Hum Genet 121:401-11. 2007
    ..These results suggest that raising HDL-C via CETP inhibition may not alter risk of CHD. Randomized control trials are needed to determine whether CETP inhibition will in reality reduce risk of CHD by raising HDL-C...
  41. ncbi A randomised trial of the short-term effect of a minimal nutrition intervention in general practice
    Siobhan Hickling
    School of Population Health, University of Western Australia, Crawley, Western Australia
    Aust N Z J Public Health 31:414-8. 2007
    ..To test the effectiveness of a minimal nutrition intervention to increase dietary intake of folate...
  42. ncbi Folate levels and cancer morbidity and mortality: prospective cohort study from Busselton, Western Australia
    Enrico Rossi
    PathCentre, QEII Medical Centre, Nedlands, WA, Australia
    Ann Epidemiol 16:206-12. 2006
    ..To test a community population for the hypothesis that carcinogenesis is related to blood folate levels...
  43. ncbi Association of PARL rs3732581 genetic variant with insulin levels, metabolic syndrome and coronary artery disease
    Brenda L Powell
    Western Australian Institute for Medical Research, UWA Centre for Medical Research, University of Western Australia, Perth, Australia
    Hum Genet 124:263-70. 2008
    ..There were significant effects of the variant on mean IMT and risk of CAD. A role for PARL in metabolic conditions cannot be excluded and more comprehensive genetic studies are warranted...
  44. ncbi Comparison of cystatin C and creatinine as predictors of cardiovascular events in a community-based elderly population
    John Beilby
    Biochemistry Section, PathWest, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia
    Clin Chem 56:799-804. 2010
    ..We compared 3 measures of renal function--serum cystatin C, serum creatinine, and calculated creatinine clearance--as predictors of subsequent cardiovascular events in a community-based population of elderly individuals...
  45. ncbi Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS)
    John P Beilby
    PathCentre, Western Australian Centre for Pathology and Medical Research, Clinical Biochemistry, Nedlands, Western Australia, Australia
    Stroke 34:869-74. 2003
    ....
  46. ncbi Abnormal glucose regulation in an Australian acute coronary syndrome population: a prospective study
    Sharon Chih
    Department of Cardiovascular Medicine, Sir Charles Gairdner Hospital, Australia
    Diabetes Res Clin Pract 81:303-9. 2008
    ..Abnormal glucose regulation (AGR) is common and an adverse risk factor in patients presenting with acute coronary syndromes (ACS)...
  47. ncbi Effect of atorvastatin on apolipoprotein B48 metabolism and low-density lipoprotein receptor activity in normolipidemic patients with coronary artery disease
    Cheryl A Dane-Stewart
    Department of Medicine, University of Western Australia, Bentley, Western Australia 6102
    Metabolism 52:1279-86. 2003
    ..This effect may, in part, explain the cardiovascular benefit of statins used in clinical trials of CAD patients with normal lipid levels...
  48. ncbi Door-to-balloon times are reduced in ST-elevation myocardial infarction by emergency physician activation of the cardiac catheterisation laboratory and immediate patient transfer
    Alexander B Willson
    Cardiovascular Medicine Department, Sir Charles Gairdner Hospital, Perth, WA, Australia
    Med J Aust 193:207-12. 2010
    ....
  49. ncbi Invasive management and late clinical outcomes in contemporary Australian management of acute coronary syndromes: observations from the ACACIA registry
    Derek P Chew
    Flinders University, Adelaide, SA
    Med J Aust 188:691-7. 2008
    ..To describe the impact of invasive management on 12-month survival among patients with suspected acute coronary syndrome (ACS) in Australia...
  50. ncbi IL18 haplotypes are associated with serum IL-18 concentrations in a population-based study and a cohort of individuals with premature coronary heart disease
    Simon R Thompson
    Department of Cardiovascular Genetics, University College London, London, United Kingdom
    Clin Chem 53:2078-85. 2007
    ..We evaluated the effect of common variation within the IL18 gene on concentrations of circulating IL-18...
  51. ncbi Aspirin for primary prevention of cardiovascular disease in women: does sex matter?
    Joseph Hung
    Med J Aust 184:260-1. 2006
    ..Recommendations for primary prevention in women need to be different...
  52. ncbi The efficacy of various alloplastic bone grafts on the healing of rat calvarial defects
    James Mah
    Division of Craniofacial Sciences and Therapeutics, University of Southern California, Los Angeles 90089-0641, USA
    Eur J Orthod 26:475-82. 2004
    ....