Research Topics
| Gary K HulseSummaryAffiliation: University of Western Australia Country: Australia Publications
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Detail Information
Publications
Improving clinical outcomes in treating heroin dependence: randomized, controlled trial of oral or implant naltrexoneGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009
Arch Gen Psychiatry 66:1108-15. 2009..Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance. Sustained-release preparations may overcome this limitation...
Reducing hospital presentations for opioid overdose in patients treated with sustained release naltrexone implantsGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
Drug Alcohol Depend 79:351-7. 2005..However, given the high prevalence of poly-substance use among dependent heroin users, programs offering this type of treatment should also focus on preventing, detecting and managing poly-substance use...
Mental health outcomes following naltrexone implant treatment for heroin-dependenceHanh T T Ngo
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
Prog Neuropsychopharmacol Biol Psychiatry 31:605-12. 2007..Oral naltrexone is an approved treatment for opioid dependence. However, the impact of sustained release naltrexone on the mental health of treated opioid users has not been studied...- Risk factors for craving and relapse in heroin users treated with oral or implant naltrexoneGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia
Biol Psychiatry 68:296-302. 2010..Few data are available on optimal blood naltrexone levels for preventing craving and/or return to heroin use. This study assesses various risk factors, including blood naltrexone level, for heroin craving and relapse to illicit opioids... - Hospital psychiatric comorbidity and its role in heroin dependence treatment outcomes using naltrexone implant or methadone maintenanceHanh T T Ngo
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, WA, Australia
J Psychopharmacol 25:774-82. 2011..Differences in research methodology were noted; recommendation for rigorous analytical methodology in future research on assessing treatment outcomes was accordingly offered... - Hospital morbidity associated with the natural history of heroin useRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, Western Australia
J Opioid Manag 4:321-7. 2008..To assess changes in hospital morbidity associated with heroin use from pre-initiation, recreational to dependent use, and changes following treatment... - Comparing drug-related hospital morbidity following heroin dependence treatment with methadone maintenance or naltrexone implantationHanh T T Ngo
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia, Australia
Arch Gen Psychiatry 65:457-65. 2008..To our knowledge, long-term sustainability of changes in patients' drug use and associated hospital morbidity posttreatment have not been studied... - Emergency department-based intervention with adolescent substance users: 12-month outcomesRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QEII Campus, Nedlands, WA 6009, Australia
Drug Alcohol Depend 79:359-63. 2005..In conclusion, while brief intervention in ED only has limited success in facilitating adolescents to attend for subsequent AOD treatment, it can significantly reduce the number of AOD related ED presentations... - Biodegradability of naltrexone-poly(DL) lactide implants in vivo assessed under ultrasound in humansGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
Addict Biol 13:364-72. 2008..Collectively, these data provide direct evidence of the in vivo absorption of the Go Medical implant over time, and its biodegradability in humans... - Motivation to quit smoking among hospitalised individuals with and without mental health disordersRanita Siru
University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Australia
Aust N Z J Psychiatry 44:640-7. 2010..A decreased level of motivation may partially explain lower cessation rates, but there is little information on motivation among inpatients with MHD... - Naltrexone implant and blood naltrexone levels over pregnancyGary K Hulse
Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
Aust N Z J Obstet Gynaecol 43:386-8. 2003 - Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer diseaseOsvaldo P Almeida
Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia
Am J Geriatr Psychiatry 16:92-8. 2008..The authors designed this study to determine if older people who smoke have decreased gray matter density in brain regions associated with incipient AD... - Assessing motivation to quit smoking in people with mental illness: a reviewRanita Siru
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA, Australia
Addiction 104:719-33. 2009..Helping these people to quit smoking is a public health priority; however, many MH professionals assume that those with mental illness are not motivated to quit... - Effectiveness of a smoking cessation intervention in older adultsRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
Addiction 102:148-55. 2007.... - Hospital morbidity and alcohol consumption in less severe psychiatric disorder: 7-year outcomesRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, D Block, QEII Campus, Nedlands, WA 6009
Br J Psychiatry 188:554-9. 2006..Substance use by people with severe psychiatric morbidity is associated with negative outcomes... - Adolescent substance use and hospital presentations: a record linkage assessment of 12-month outcomesRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
Drug Alcohol Depend 79:365-71. 2005..CONCLUSIONS: BI can be delivered in ED and reduce hospital AOD morbidity associated with the use of drugs other than alcohol. Interventions should focus on those with prior AOD events and "other drugs" presentations... - Dementia associated with alcohol and other drug useGary K Hulse
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
Int Psychogeriatr 17:S109-27. 2005..Health promotion programs designed to decrease tobacco smoking and "harmful" alcohol use (and possibly other drug use) may decrease the burden of cognitive impairment and perhaps dementia in later life... - Blood morphine levels in naltrexone-exposed compared to non-naltrexone-exposed fatal heroin overdosesDiane E Arnold-Reed
School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, Western Australia
Addict Biol 8:343-50. 2003..Other drug use in relation to heroin-related fatalities is discussed. Findings do not support the hypothesis that prior exposure to naltrexone increases sensitivity to heroin toxicity... - A systematic review of the effectiveness of brief interventions with substance using adolescents by type of drugRobert J Tait
School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, WA 6009, Australia
Drug Alcohol Rev 22:337-46. 2003..The effect of BI with multiple substances appears substantial but the small sample cautions against expansive generalization...