G K Hulse

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi Impediments to screening for hazardous alcohol use and dependence in general hospital psychiatric inpatients
    G K Hulse
    Sir Charles Gairdner Hospital, Perth, Australia
    Aust N Z J Psychiatry 35:606-12. 2001
  2. ncbi Histological changes over time around the site of sustained release naltrexone-poly(DL-lactide) implants in humans
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Crawley, and Department of Pathology, Royal Perth Hospital, WA, Australia
    J Control Release 108:43-55. 2005
  3. ncbi A pilot study to assess the impact of naltrexone implant on accidental opiate overdose in 'high-risk' adolescent heroin users
    Gary K Hulse
    University School of Psychiatry and CLinical Neurosciences, QE II Medical Centre, Nedlands, Western Australia
    Addict Biol 8:337-42. 2003
  4. ncbi Naltrexone implant and blood naltrexone levels over pregnancy
    Gary K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
    Aust N Z J Obstet Gynaecol 43:386-8. 2003
  5. ncbi Methadone maintenance vs. implantable naltrexone treatment in the pregnant heroin user
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, University of Western Australia, School of Psychiatry and Clinical Neurosciences, Perth, Australia
    Int J Gynaecol Obstet 85:170-1. 2004
  6. ncbi Management of the impaired doctor
    Gary Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia
    Aust Fam Physician 33:703-7. 2004
  7. ncbi Blood naltrexone and 6-beta-naltrexol levels following naltrexone implant: comparing two naltrexone implants
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Addict Biol 9:59-65. 2004
  8. ncbi The quantification of mortality resulting from the regular use of illicit opiates
    G K Hulse
    Department of Psychiatry and Behavioural Science, Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 94:221-9. 1999
  9. ncbi Assessing the relationship between maternal opiate use and antepartum haemorrhage
    G K Hulse
    Department of Psychiatry and Behavioural Science, University of Western Australia, Australia
    Addiction 93:1553-8. 1998
  10. ncbi Assessing the relationship between maternal opiate use and neonatal mortality
    G K Hulse
    Department of Public Health, Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 93:1033-42. 1998

Collaborators

Detail Information

Publications52

  1. ncbi Impediments to screening for hazardous alcohol use and dependence in general hospital psychiatric inpatients
    G K Hulse
    Sir Charles Gairdner Hospital, Perth, Australia
    Aust N Z J Psychiatry 35:606-12. 2001
    ....
  2. ncbi Histological changes over time around the site of sustained release naltrexone-poly(DL-lactide) implants in humans
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Crawley, and Department of Pathology, Royal Perth Hospital, WA, Australia
    J Control Release 108:43-55. 2005
    ..The results of the study indicated that the Australian naltrexone-poly(DL-lactide) implant is well tolerated and may have a role for use in the management of medical conditions such as heroin dependence...
  3. ncbi A pilot study to assess the impact of naltrexone implant on accidental opiate overdose in 'high-risk' adolescent heroin users
    Gary K Hulse
    University School of Psychiatry and CLinical Neurosciences, QE II Medical Centre, Nedlands, Western Australia
    Addict Biol 8:337-42. 2003
    ..These encouraging findings now require validation using a larger cohort over an extended period..
  4. ncbi Naltrexone implant and blood naltrexone levels over pregnancy
    Gary K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
    Aust N Z J Obstet Gynaecol 43:386-8. 2003
  5. ncbi Methadone maintenance vs. implantable naltrexone treatment in the pregnant heroin user
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, University of Western Australia, School of Psychiatry and Clinical Neurosciences, Perth, Australia
    Int J Gynaecol Obstet 85:170-1. 2004
  6. ncbi Management of the impaired doctor
    Gary Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia
    Aust Fam Physician 33:703-7. 2004
    ..The lifetime prevalence of substance abuse disorders among doctors in Australia has been estimated to be approximately 8%. These disorders can interfere with a doctor's ability to function and pose a risk to patient welfare and safety.'..
  7. ncbi Blood naltrexone and 6-beta-naltrexol levels following naltrexone implant: comparing two naltrexone implants
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Addict Biol 9:59-65. 2004
    ..3 months compared to 3 months, respectively. The implications of this in managing the heroin-dependent patient, especially those who find it difficult to shift away from dependent use patterns, are discussed...
  8. ncbi The quantification of mortality resulting from the regular use of illicit opiates
    G K Hulse
    Department of Psychiatry and Behavioural Science, Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 94:221-9. 1999
    ..Studies were included only where AIDS-specific mortality accounted for less than 2% of total mortality...
  9. ncbi Assessing the relationship between maternal opiate use and antepartum haemorrhage
    G K Hulse
    Department of Psychiatry and Behavioural Science, University of Western Australia, Australia
    Addiction 93:1553-8. 1998
    ..As a consequence, most published studies lack statistical power due to the small number of cases. We combined all suitable published data in a meta-analysis to assess the association more accurately...
  10. ncbi Assessing the relationship between maternal opiate use and neonatal mortality
    G K Hulse
    Department of Public Health, Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 93:1033-42. 1998
    ....
  11. ncbi The relationship between maternal use of heroin and methadone and infant birth weight
    G K Hulse
    Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 92:1571-9. 1997
    ..We undertook a number of meta-analyses on reduction in mean birth weight and incidence of low birth weight to estimate more precisely the effect of illicit heroin and methadone...
  12. ncbi Dementia associated with alcohol and other drug use
    Gary K Hulse
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Int Psychogeriatr 17:S109-27. 2005
    ..Health promotion programs designed to decrease tobacco smoking and "harmful" alcohol use (and possibly other drug use) may decrease the burden of cognitive impairment and perhaps dementia in later life...
  13. ncbi A comparison of mental health hospital admissions in a cohort of heroin users prior to and after rapid opiate detoxification and oral naltrexone maintenance
    D E Arnold-Reed
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia
    Am J Drug Alcohol Abuse 33:655-64. 2007
    ..All categories subsequently declined to baseline levels by 36 months following treatment. The authors conclude that treatment for heroin dependence reduces risk of MH admissions...
  14. ncbi Achieving long-term continuous blood naltrexone and 6-beta-naltrexol coverage following sequential naltrexone implants
    G K Hulse
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia
    Addict Biol 9:67-72. 2004
    ..4 g naltrexone implants. These extended periods of coverage will offer significant benefits for managing the heroin-dependent patient...
  15. doi Minor pathological changes are induced by naltrexone-poly(DL-lactide) implants in pregnant rats
    W O Farid
    Experimental and Regenerative Neurosciences, School of Animal Biology M317, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    J Biomed Mater Res A 91:964-74. 2009
    ..We conclude that the Australian naltrexone-poly(DL-lactide) implant is tolerated in pregnant rats, reinforcing its potential role for managing alcohol and heroin dependence in pregnant humans...
  16. ncbi Blood naltrexone levels over time following naltrexone implant
    H T T Ngo
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, D Block, Nedlands, Western Australia 6009, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 32:23-8. 2008
    ..The study's objective was to determine the period of therapeutic coverage (>or=2 ng/ml) provided by a 3.3 g naltrexone subcutaneous implant compared with existing data on 1.1 g and 2.2 g implants...
  17. ncbi Use of oral and implantable naltrexone in the management of the opioid impaired physician
    G K Hulse
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre
    Anaesth Intensive Care 31:196-201. 2003
    ....
  18. ncbi Obstetric and neonatal outcomes associated with maternal naltrexone exposure
    G K Hulse
    Department of Psychiatry and Behavioural Science, Faculty of Medicine, University of Western Australia, Nedlands, Australia
    Aust N Z J Obstet Gynaecol 41:424-8. 2001
    ..These case data indicate that naltrexone maintenance may have a role in the management of the pregnant heroin user...
  19. ncbi Adolescent emergency department presentations with alcohol- or other drug-related problems in Perth, Western Australia
    G K Hulse
    University Department of Psychiatry and Behavioural Science, QE II Medical Centre, Nedlands
    Addiction 96:1059-67. 2001
    ..In addition, Indigenous youth are over-represented in hospital presentations, but there is currently a lack of evaluated interventions designed for them...
  20. ncbi A possible role for implantable naltrexone in the management of the high-risk pregnant heroin user
    G K Hulse
    King Edward Memorial Hospital, and the Australian Medical Procedures Research Foundation, University Department of Psychiatry and Behavioural Science, University of Western Australia, Nedlands, Australia
    Aust N Z J Obstet Gynaecol 42:93-4. 2002
  21. ncbi Methadone and the pregnant user: a matter for careful clinical consideration
    G K Hulse
    Department of Psychiatry and Behavioural Science, University of Western Australia, Australia
    Aust N Z J Obstet Gynaecol 41:329-32. 2001
    ..The need to develop innovative services appropriate for pregnant women who continue regular heroin use, and for well-designed studies that define best practice for the management of these women is evident...
  22. ncbi Assessing the relationship between maternal cocaine use and abruptio placentae
    G K Hulse
    Faculty of Medicine and Dentistry, University of Western Australia, Australia
    Addiction 92:1547-51. 1997
    ..77-5.46). The strength and consistency of the association, its biological plausibility and the results of experimental studies in animals all suggest that cocaine use during pregnancy causes abruptio placentae...
  23. ncbi Acculturation and eating disorders in Asian and Caucasian Australian adolescent girls
    Piangchai S Jennings
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, Western Australia, Australia
    Psychiatry Clin Neurosci 59:56-61. 2005
    ..Within the Asian group, the less acculturated girls had higher scores on the EAT-26 and the EDI-2 than the more acculturated. Less acculturated Asian girls appeared to have unhealthier attitudes and psychopathology toward eating...
  24. ncbi Hepatitis C virus eradication in intravenous drug users maintained with subcutaneous naltrexone implants
    Gary P Jeffrey
    School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia
    Hepatology 45:111-7. 2007
    ..This result is comparable to that reported in hospital-based clinics in non-IDU patients. The side effect profile and compliance was also similar. HCV antiviral therapy should be offered to this large and currently under treated group...
  25. ncbi Acculturation and eating disorders in Asian and Caucasian Australian university students
    Piangchai S Jennings
    School of Psychiatry and Clinical Neurosciences at UDP Level 4, Princess Margaret Hospital for Children, The University of Western Australia, GPO Box D184, Perth, Western Australia 6840, Australia
    Eat Behav 7:214-9. 2006
    ....
  26. ncbi Eating disorder attitudes and psychopathology in Caucasian Australian, Asian Australian and Thai university students
    Piangchai S Jennings
    School of Psychiatry and Clinical Neurosciences, Princess Margaret Hospital for Children, The University of Western Australia, Perth, Australia
    Aust N Z J Psychiatry 40:143-9. 2006
    ..To examine eating disorder attitudes and psychopathology among female university students in Australia and Thailand...
  27. ncbi The identification and management of the drug impaired doctor
    Eric Khong
    School of Psychiatry and Neurosciences, Faculty of Medicine and Dentistry, University of Western Australia
    Aust Fam Physician 31:1097-100. 2002
    ..However, doctors have traditionally been discouraged from admitting vulnerability and frequently fail to recognise or respond to early signs of problem alcohol and drug use...
  28. pmc The effects of maternally administered methadone, buprenorphine and naltrexone on offspring: review of human and animal data
    W O Farid
    School of Animal Biology, The University of Western Australia, Nedlands, WA 6009, Australia
    Curr Neuropharmacol 6:125-50. 2008
    ..While each treatment is likely to have maternal advantages and disadvantages, studies are urgently required to determine which is optimal for offspring in the short and long term...
  29. ncbi Injecting drug use and skin lesions
    Moira G Sim
    School of Psychiatry and Clinical Neurosciences, The University of Western Australia
    Aust Fam Physician 33:519-22. 2004
    ..Many illicit drugs can be injected, with this mode of administration associated with a range of skin morbidities...
  30. ncbi Cannabis and psychosis
    Moira G Sim
    School of Psychiatry and Clinical Neurosciences, University of Western Australia
    Aust Fam Physician 33:229-32. 2004
    ..Cannabis use is commonly identified in people who present with psychosis...
  31. ncbi Mental health outcomes following naltrexone implant treatment for heroin-dependence
    Hanh T T Ngo
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 31:605-12. 2007
    ..Oral naltrexone is an approved treatment for opioid dependence. However, the impact of sustained release naltrexone on the mental health of treated opioid users has not been studied...
  32. ncbi A comparison of rapid (opioid) detoxification with clonidine-assisted detoxification for heroin-dependent persons
    Diane E Arnold-Reed
    Unit for Research and Education in Drugs and Alcohol, School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Crawley
    J Opioid Manag 1:17-23. 2005
    ..The level of patient satisfaction between the two treatments was also similar. The authors discuss why ROD is considered more effective than CD...
  33. ncbi Opioid overdose deaths can occur in patients with naltrexone implants
    Gary K Hulse
    Med J Aust 187:54; author reply 56-7. 2007
  34. ncbi Cough mixtures: not always for cough
    Moira G Sim
    Edith Cowan University, School of Psychiatry and Clinical Neurosciences, The University of Western Australia
    Aust Fam Physician 33:327-31. 2004
    ..Opioid based cough mixtures are readily available to the public and are generally used safely. However, like alcohol, their use can sometimes be a significant part of a dependence problem...
  35. ncbi Sustained-release naltrexone: novel treatment for opioid dependence
    Sandra D Comer
    College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, Department of Psychiatry, Unit 120, New York, NY 10032, USA
    Expert Opin Investig Drugs 16:1285-94. 2007
    ..The present paper describes the development of sustained-release naltrexone formulations and discusses the clinical issues associated with their use in treating opioid dependence...
  36. ncbi A review of the validity of the General Health Questionnaire in adolescent populations
    Robert J Tait
    Department of Psychiatry and Behavioural Science, University of Western Australia, QE11 Campus, Nedlands 6009, Western Australia, Australia
    Aust N Z J Psychiatry 36:550-7. 2002
    ..Although the GHQ has been extensively used and validated with adults and has been frequently used with adolescents, the validity data for this group are sporadic...
  37. doi Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer disease
    Osvaldo P Almeida
    Western Australia Centre for Health and Ageing, School of Psychiatry and Clinical Neurosciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia 6009, Australia
    Am J Geriatr Psychiatry 16:92-8. 2008
    ..The authors designed this study to determine if older people who smoke have decreased gray matter density in brain regions associated with incipient AD...
  38. doi Comparing drug-related hospital morbidity following heroin dependence treatment with methadone maintenance or naltrexone implantation
    Hanh T T Ngo
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Western Australia, Australia
    Arch Gen Psychiatry 65:457-65. 2008
    ..To our knowledge, long-term sustainability of changes in patients' drug use and associated hospital morbidity posttreatment have not been studied...
  39. ncbi Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies
    Osvaldo P Almeida
    Department of Psychiatry and Behavioural Science, University of Western Australia, Perth, Australia
    Addiction 97:15-28. 2002
    ..To investigate the risk of Alzheimer's disease (AD) associated with smoking...
  40. ncbi Effectiveness of a smoking cessation intervention in older adults
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Australia
    Addiction 102:148-55. 2007
    ....
  41. ncbi Six-month outcomes associated with a brief alcohol intervention for adult in-patients with psychiatric disorders
    Gary K Hulse
    Sir Charles Gairdner, Bentley and Royal Perth Hospitals, Perth, Western Australia
    Drug Alcohol Rev 21:105-12. 2002
    ..They are effective across the mid-range of GSI severity scores for in-patients. Screening and brief interventions can and should be incorporated into the routine assessment and management in psychiatric units...
  42. ncbi Multiple hospital presentations by adolescents who use alcohol or other drugs
    Robert J Tait
    University Department of Psychiatry and Behavioural Science, QE II Medical Centre, Nedlands, Western Australia
    Addiction 97:1269-75. 2002
    ..To investigate 'all cause' and the subset of 'alcohol or other drug' (AOD) related hospital emergency department (ED) presentations over 12 months by adolescents with a previously identified AOD ED presentation...
  43. ncbi A systematic review of the effectiveness of brief interventions with substance using adolescents by type of drug
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, WA 6009, Australia
    Drug Alcohol Rev 22:337-46. 2003
    ..The effect of BI with multiple substances appears substantial but the small sample cautions against expansive generalization...
  44. ncbi Blood morphine levels in naltrexone-exposed compared to non-naltrexone-exposed fatal heroin overdoses
    Diane E Arnold-Reed
    School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Nedlands, Western Australia
    Addict Biol 8:343-50. 2003
    ..Other drug use in relation to heroin-related fatalities is discussed. Findings do not support the hypothesis that prior exposure to naltrexone increases sensitivity to heroin toxicity...
  45. ncbi Adolescent substance use and hospital presentations: a record linkage assessment of 12-month outcomes
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
    Drug Alcohol Depend 79:365-71. 2005
    ....
  46. pmc Reducing hospital presentations for opioid overdose in patients treated with sustained release naltrexone implants
    Gary K Hulse
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, WA 6009, Australia
    Drug Alcohol Depend 79:351-7. 2005
    ..A sub-group of this cohort (n=146; 83 males) had previously received treatment with oral naltrexone, which also allowed a comparison of overdoses pre- and post-oral and also post-implant treatments...
  47. ncbi Emergency department-based intervention with adolescent substance users: 12-month outcomes
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QEII Campus, Nedlands, WA 6009, Australia
    Drug Alcohol Depend 79:359-63. 2005
    ..In conclusion, while brief intervention in ED only has limited success in facilitating adolescents to attend for subsequent AOD treatment, it can significantly reduce the number of AOD related ED presentations...
  48. ncbi Five-year outcomes of a brief alcohol intervention for adult in-patients with psychiatric disorders
    Gary K Hulse
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, Nedlands, WA, Australia
    Addiction 98:1061-8. 2003
    ....
  49. ncbi Validity and psychometric properties of the General Health Questionnaire-12 in young Australian adolescents
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, QE II Medical Centre, Nedlands, Western Australia 6009, Australia
    Aust N Z J Psychiatry 37:374-81. 2003
    ..The General Health Questionnaire (GHQ) is a measure of current mental wellbeing that has been extensively validated with adults. The instrument has also been used with adolescents...
  50. ncbi Hospital morbidity and alcohol consumption in less severe psychiatric disorder: 7-year outcomes
    Robert J Tait
    School of Psychiatry and Clinical Neurosciences, University of Western Australia, D Block, QEII Campus, Nedlands, WA 6009
    Br J Psychiatry 188:554-9. 2006
    ..Substance use by people with severe psychiatric morbidity is associated with negative outcomes...
  51. ncbi Effectiveness of a brief-intervention and continuity of care in enhancing attendance for treatment by adolescent substance users
    Robert J Tait
    University School of Psychiatry and CLinical Neurosciences, Nedlands, WA 6009, Australia
    Drug Alcohol Depend 74:289-96. 2004
    ..To evaluate the effectiveness of a brief intervention enhanced by a consistent support person in facilitating attendance for substance use treatment following a hospital alcohol or other drug (AOD) presentation...
  52. ncbi Acute pain and opioid seeking behaviour
    Moira G Sim
    Edith Cowan University, Western Australia
    Aust Fam Physician 33:1009-12. 2004
    ..Acute pain is a common presentation associated with opioid seeking behaviour...