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Species | J M HodgsonSummaryAffiliation: University of Western Australia Country: Australia Publications
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Publications
Short-term effects of polyphenol-rich black tea on blood pressure in men and womenJonathan M Hodgson
School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, GPO Box X2213, Perth, Western Australia 6847, Australia
Food Funct 4:111-5. 2013..8) bpm, and -1.9 (95% CI, -3.7, -0.2) bpm, respectively; P < 0.05 for both), but not during the day-time. These results suggest that the longer-term benefits of black tea on blood pressure are unlikely to be due to short-term changes...- Long-term effects of a protein-enriched diet on blood pressure in older womenJonathan M Hodgson
Royal Perth Hospital Unit, School of Medicine and Pharmacology, University of Western Australia, GPO Box X2213, Perth, Western Australia 6847, Australia
Br J Nutr 107:1664-72. 2012..Therefore, the present study did not provide evidence that a higher whey protein intake in older women can have prolonged effects on blood pressure... 
Effects of tea and tea flavonoids on endothelial function and blood pressure: a brief reviewJ M Hodgson
University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
Clin Exp Pharmacol Physiol 33:838-41. 2006..5. Overall, the available data suggest that the effects of tea flavonoids on endothelial function and, perhaps, blood pressure may be responsible, at least in part, for any benefits of drinking tea on the risk of cardiovascular disease...- Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjectsJonathan M Hodgson
University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, and the Western Australian Institute for Medical Research, Perth, Australia
Br J Nutr 97:842-6. 2007..Given that results of population studies have generally shown a negative association between tea intake and tHcy, the significance of these findings to CVD risk remains uncertain... - Tea flavonoids and cardiovascular healthJonathan M Hodgson
School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
Mol Aspects Med 31:495-502. 2010..Data supporting reduced oxidative damage, inflammation, platelet activation, blood pressure, and risk of type 2 diabetes with tea (flavonoids) remains inadequate to draw any conclusions... - Effects of increasing dietary protein and fibre intake with lupin on body weight and composition and blood lipids in overweight men and womenJ M Hodgson
School of Medicine and Pharmacology, University of Western Australia, and the WAIMR Centre for Food and Genomic Medicine, Perth, Western Australia, Australia
Int J Obes (Lond) 34:1086-94. 2010..In addition, several studies have suggested that lupin may reduce cholesterol concentrations and benefit glucose and insulin metabolism... - Chocolate consumption and bone density in older womenJonathan M Hodgson
Royal Perth Hospital Unit, the University of Western Australia School of Medicine and Pharmacology, Perth, Australia
Am J Clin Nutr 87:175-80. 2008..Nutrition is important for the development and maintenance of bone structure and for the prevention of osteoporosis and fracture. The relation of chocolate intake with bone has yet to be investigated... - Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humansJonathan M Hodgson
University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
J Nutr 137:363-7. 2007..4 (-3.4, 0.5) mg/L], and plasma fibrinogen concentrations [-0.08 (-0.40. 0.24) g/L]. Our results suggest that partial replacement of dietary carbohydrate with protein from lean red meat does not elevate oxidative stress or inflammation... - Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trialR Belski
School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
Int J Obes (Lond) 35:810-9. 2011..Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre... - Sesame supplementation does not improve cardiovascular disease risk markers in overweight men and womenJ H Y Wu
School of Medicine and Pharmacology, University of Western Australia, PO Box X2213 GPO, Perth WA 6847, Australia
Nutr Metab Cardiovasc Dis 19:774-80. 2009..We aimed to investigate the effects of sesame supplementation in humans on blood lipids, blood pressure, systemic oxidative stress, inflammatory biomarkers and mammalian lignan metabolism... - Recent developments concerning diet and hypertensionL J Beilin
University Department of Medicine, Royal Perth Hospital, University of Western Australia and HeartSearch WA, Perth, Western Australia, Australia
Clin Exp Pharmacol Physiol 28:1078-82. 2001..3. Regular coffee drinking raised blood pressure in older hypertensives, whereas potential antihypertensive effects of dietary anti-oxidants require further scrutiny... - Acute effects of ingestion of black and green tea on lipoprotein oxidationJ M Hodgson
University of Western Australia, Department of Medicine, and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
Am J Clin Nutr 71:1103-7. 2000..The absence of effects in previous studies may be due to the isolation of LDL particles from polyphenolic compounds that are present in the aqueous phase of serum... - Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunctionWai Mun Loke
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Arterioscler Thromb Vasc Biol 30:749-57. 2010.... - Non pharmacologic therapy and lifestyle factors in hypertensionL J Beilin
Department of Medicine, University of Western Australia, Royal Perth Hospital, Australia
Blood Press 10:352-65. 2001.... - Dietary protein and soluble fiber reduce ambulatory blood pressure in treated hypertensivesV Burke
Department of Medicine, University of Western Australia, Royal Perth Hospital and West Australian Heart Research Institute, Perth, Australia
Hypertension 38:821-6. 2001..These findings have important implications for the prevention and management of hypertension, particularly in populations in which high blood pressure is prevalent in association with diets low in protein, fiber, or both... - Effects of regular ingestion of black tea on haemostasis and cell adhesion molecules in humansJ M Hodgson
University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia
Eur J Clin Nutr 55:881-6. 2001..To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules... - Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetesMichael W Clarke
Department of Core Clinical Pathology and Biochemistry, Royal Perth Hospital, University of Western Australia, Perth, Australia
Am J Clin Nutr 83:95-102. 2006..Changes in serum tocopherol closely reflect changes in cellular concentrations of tocopherols after supplementation... - Effects of alpha-tocopherol and mixed tocopherol supplementation on markers of oxidative stress and inflammation in type 2 diabetesJason H Y Wu
School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
Clin Chem 53:511-9. 2007.... - Gallic acid metabolites are markers of black tea intake in humansJ M Hodgson
Department of Medicine, University of Western Australia, Royal Perth Hospital, Perth, Western Australia, Australia
J Agric Food Chem 48:2276-80. 2000..It is suggested that these compounds have the potential to be used as markers of black tea intake... - Tea intake is inversely related to blood pressure in older womenJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, Western Australia, Australia
J Nutr 133:2883-6. 2003..The observed associations for both tea intake and 4-O-methylgallic acid are consistent with the hypothesis that long-term regular ingestion of tea may have a favorable effect on blood pressure in older women... - Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy menWai Mun Loke
School of Medicine and Pharmacology and the School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Perth, Western Australia
Am J Clin Nutr 88:1018-25. 2008..Dietary flavonoids may improve endothelial function and ultimately lead to beneficial cardiovascular effects... - Vitamin E supplementation and hepatic drug metabolism in humansMichael W Clarke
Department of Core Clinical Pathology and Biochemistry, PathWest Laboratory Medicine, Royal Perth Hospital, University of Western Australia, Perth, Western Australia, Australia
J Cardiovasc Pharmacol 54:491-6. 2009..These findings do not support the hypothesis that alpha-TOH supplementation interferes with hepatic CYP3A4-mediated drug metabolism... - Isoflavonoids do not inhibit in vivo lipid peroxidation in subjects with high-normal blood pressureJ M Hodgson
University of Western Australia Department of Medicine and the Western Australian Heart Research Institute, Royal Perth Hospital, Australia
Atherosclerosis 145:167-72. 1999..These results are not consistent with the suggestion that the two soy derived isoflavonoids have in vivo antioxidant activity at a level of intake achievable by dietary means and in subjects with high-normal BP... - Effects of isoflavonoids on blood pressure in subjects with high-normal ambulatory blood pressure levels: a randomized controlled trialJ M Hodgson
University of Western Australia Department of Medicine, Royal Perth Hospital, Australia
Am J Hypertens 12:47-53. 1999..Therefore, these results do not support the hypothesis that isoflavonoids, and genistein in particular, are major contributors to the BP lowering effect of vegetarian diets... - Effects on blood pressure of drinking green and black teaJ M Hodgson
University of Western Australia Department of Medicine and the Western Australian Heart Research Institute, Royal Perth Hospital, Australia
J Hypertens 17:457-63. 1999.... - Lupin-enriched bread increases satiety and reduces energy intake acutelyYa P Lee
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Am J Clin Nutr 84:975-80. 2006..04) and resulted in significantly lower mean 3-h plasma ghrelin concentrations (P = 0.009). CONCLUSION: A novel food enriched in protein and fiber derived from lupin kernel flour significantly influences energy intake acutely... - The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trialNatalie C Ward
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
J Hypertens 25:227-34. 2007..Our aim was to investigate the effect of alpha-tocopherol and gamma-tocopherol supplementation on 24-h ambulatory blood pressure (BP) and heart rate, vascular function and oxidative stress in individuals with type 2 diabetes... - The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trialNatalie C Ward
School of Medicine and Pharmacology, University of Western Australia and West Australian Institute for Medical Research WAIMR, Perth, Australia
J Hypertens 23:427-34. 2005..Thus, dietary antioxidants may beneficially influence blood pressure (BP) and endothelial function by reducing oxidative stress... - Skim milk compared with a fruit drink acutely reduces appetite and energy intake in overweight men and womenEmma R Dove
School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia
Am J Clin Nutr 90:70-5. 2009..Several studies show that proteins, including whey and casein, are more satiating than carbohydrates. It follows that skim milk would be more satiating than sugar-rich beverages. However, this has yet to be shown... - A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressureNatalie C Ward
Schools of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Hypertension 51:1393-8. 2008..The positive association between the CYP4F2 GA/AA genotype and both systolic blood pressure and 20-hydroxyeicosatetraenoic acid excretion strengthens a role for 20-hydroxyeicosatetraenoic acid in the modulation of blood pressure... - Tea flavonoids and cardiovascular diseaseJonathan M Hodgson
School of Medicine and Pharmacology, GPO Box X2213, Perth, WA, 6847, Australia
Asia Pac J Clin Nutr 17:288-90. 2008..Additional studies are needed to investigate whether regular consumption of tea can reduce blood pressure, inflammation and the risk of thrombosis. The evidence for benefit on oxidative damage and cholesterol reduction remains weak... - Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studiesJason H Y Wu
School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia, Perth, Western Australia, Australia
Hypertension 54:1151-8. 2009..These results suggest that sesame lignans could be used for the investigation of potential roles of 20-HETE in humans... - A metabolite profiling approach to identify biomarkers of flavonoid intake in humansWai Mun Loke
School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, Perth, WA 6000, Australia
J Nutr 139:2309-14. 2009..Potential biomarkers of (-)-epicatechin were not identified. These urinary biomarkers may provide an accurate indication of flavonoid exposure... - 20-Hydroxyeicosatetraenoic acid is not associated with circulating insulin in lean to overweight humansNatalie C Ward
School of Medicine and Pharmacology RPH, University of Western Australia, Level 4, Rear 50 Murray Street, Perth, WA 6000, Australia
Diabetes Res Clin Pract 74:197-200. 2006..The results of the present study suggest that the observed positive association between urinary 20-HETE excretion and BMI may not be related to circulating insulin levels or insulin resistance... - Acute effects of tea on fasting and postprandial vascular function and blood pressure in humansJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, Western Australian Institute for Medical Research WAIMR, Royal Perth Hospital Unit, Perth, Western Australia
J Hypertens 23:47-54. 2005..Controlled trials in humans have found that ingestion of tea can improve endothelial function, but also cause a rapid onset acute increase in blood pressure... - Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humansNatalie C Ward
School of Medicine and Pharmacology, University of Western Australia, and Western Australian Institute for Medical Research, Perth, Australia
J Agric Food Chem 52:5545-9. 2004..002). The observed increase in 3-HPP is in line with the suggestion that this compound is a major phenolic acid breakdown product of proanthocyanidin metabolism in vivo... - Phenolic acid metabolites as biomarkers for tea- and coffee-derived polyphenol exposure in human subjectsJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia
Br J Nutr 91:301-6. 2004.... - Oxidative stress in human hypertension: association with antihypertensive treatment, gender, nutrition, and lifestyleNatalie C Ward
School of Medicine and Pharmacology, University of Western Australia, Western Australian Institute for Medical Research WAIMR, Perth, Australia
Free Radic Biol Med 36:226-32. 2004..The results do not support the hypothesis that treated or untreated hypertensive subjects are under increased oxidative stress compared with normotensive controls... - Can black tea influence plasma total homocysteine concentrations?Jonathan M Hodgson
School of Medicine and Pharmacology, University of Western Australia, and the Western Australian Institute for Medical Research, Royal Perth Hospital, Perth, Australia
Am J Clin Nutr 77:907-11. 2003..This may result in elevations in plasma total homocysteine (tHcy) concentrations after ingestion of polyphenol-rich beverages such as tea... - Leukocyte count and vascular function in Type 2 diabetic subjects with treated hypertensionRichard J Woodman
Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
Atherosclerosis 163:175-81. 2002..This study examined the associations between vascular function and markers of inflammation in Type 2 diabetic subjects with treated hypertension... - Acute effects of ingestion of black tea on postprandial platelet aggregation in human subjectsJonathan M Hodgson
University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Australia
Br J Nutr 87:141-5. 2002..The results of this study do not support the suggestion that reduced postprandial platelet aggregability contributes to any benefits of black tea on cardiovascular risk... - Regular ingestion of black tea improves brachial artery vasodilator functionJonathan M Hodgson
Department of Medicine, University of Western Australia and HeartSearch, Royal Perth Hospital, G P O Box X2213, Perth, Western Australia 6847, Australia
Clin Sci (Lond) 102:195-201. 2002..These differences remained after adjustment for age, sex and body mass index. These results suggest that one mechanism by which black tea may reduce cardiovascular risk is via improved vasodilator function of conduit arteries... - Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjectsNatalie C Ward
School of Medicine and Pharmachology, University of Western Ausralia, Perth, Australia
Free Radic Biol Med 38:1032-6. 2005..In conclusion, the study highlights the positive association observed between 20-HETE excretion and markers of oxidative damage. The study also provides evidence that gamma-GT may be a useful marker of oxidative stress... - Regular ingestion of tea does not inhibit in vivo lipid peroxidation in humansJonathan M Hodgson
University of Western Australia, Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, WA 6001, Australia
J Nutr 132:55-8. 2002..These results do not support the suggestion that polyphenolic antioxidants derived from tea inhibit in vivo lipid peroxidation... - Drinking tea is associated with lower plasma total homocysteine in older womenJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, PO Box X2213, Perth, WA 6001, Australia
Asia Pac J Clin Nutr 15:253-8. 2006..The observed lower tHcy in women with higher tea intake is consistent in direction and magnitude with previous epidemiological studies, but any mechanisms remain unclear... - Red wine and beer elevate blood pressure in normotensive menRenate R Zilkens
School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Western Australian Institute for Medical Research, Perth, Western Australia
Hypertension 45:874-9. 2005.... - Partial substitution of carbohydrate intake with protein intake from lean red meat lowers blood pressure in hypertensive personsJonathan M Hodgson
University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, GPO Box X2213, Perth, WA 6001, Australia
Am J Clin Nutr 83:780-7. 2006..Compared with carbohydrate intake, dietary intake of plant protein can lower blood pressure in humans, but the effects of animal protein intake on blood pressure have yet to be investigated... - Is reversal of endothelial dysfunction by tea related to flavonoid metabolism?Jonathan M Hodgson
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Br J Nutr 95:14-7. 2006..Thus, differences in flavonoid metabolism could be related to the level of benefit of dietary flavonoids on the risk of CVD... - Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetesJ M Hodgson
University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia
Eur J Clin Nutr 56:1137-42. 2002..SPONSORSHIP: This study was supported by a grant from the NH&MRC, Australia... - Effects of lupin kernel flour-enriched bread on blood pressure: a controlled intervention studyYa P Lee
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Am J Clin Nutr 89:766-72. 2009..Available data suggest that substitution of refined carbohydrate in the diet with protein and fiber may benefit blood pressure. Lupin kernel flour is high in protein and fiber and low in carbohydrate... - Nitration of gamma-tocopherol prevents its oxidative metabolism by HepG2 cellsJason H Y Wu
School of Medicine and Pharmacology, University of Western Australia, PO Box X2213, GPO Perth 6847, West Australia
Free Radic Biol Med 39:483-94. 2005..Whether 5-NO2-gammaT could be metabolised via other pathways in vivo requires further investigation... - Can coenzyme Q10 improve vascular function and blood pressure? Potential for effective therapeutic reduction in vascular oxidative stressJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology and the Western Australian Institute for Medical Research, Royal Perth Hospital, Western Australia, Australia
Biofactors 18:129-36. 2003..The particularly relevant groups of patients for these studies are those with insulin resistance, type 2 diabetes, hypertension and the metabolic syndrome... - Protein, fibre and blood pressure: potential benefit of legumesYa Ping Lee
University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, University of Western Australia, Perth, Western Australia, Australia
Clin Exp Pharmacol Physiol 35:473-6. 2008..5. This review assesses the evidence for effects of protein and fibre to reduce blood pressure and the potential of incorporation of legumes into the daily diet as a feasible approach to achieving such benefits for blood pressure... - Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activityWai Mun Loke
School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
Biochem Pharmacol 75:1045-53. 2008.... - Quercetin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidationWai Mun Loke
School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, Medical Research Foundation Building, Level 4, 50 Murray Street, Perth, WA 6000, Australia
J Agric Food Chem 56:3609-15. 2008..Dietary flavonoids that could modify MPO activity could protect lipoproteins from damage in chronic inflammatory states such as cardiovascular disease... - Dietary fibre and blood pressureJonathan M Hodgson
J Hypertens 22:25-6. 2004 - Dietary flavonoids and cardiovascular disease: does the emperor have any clothes?Jonathan M Hodgson
J Hypertens 23:1461-3. 2005 - Tea drinking is associated with benefits on bone density in older womenAmanda Devine
Nutrition Program, School of Exercise, Biomedical and Health Science, Edith Cowan University, 100 Joondalup Drive, Joondalup WA 6027 Australia
Am J Clin Nutr 86:1243-7. 2007..Impaired hip structure assessed by dual-energy X-ray absorptiometry (DXA) areal bone mineral density (aBMD) is an independent predictor for osteoporotic hip fracture. Some studies suggest that tea intake may protect against bone loss...