J M Hodgson

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. doi request reprint Relationships of vascular function with measures of ambulatory blood pressure variation
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, GPO Box X2213 Perth, Western Australia 6847, Australia Electronic address
    Atherosclerosis 233:48-54. 2014
  2. doi request reprint Black tea lowers the rate of blood pressure variation: a randomized controlled trial
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 97:943-50. 2013
  3. doi request reprint Short-term effects of polyphenol-rich black tea on blood pressure in men and women
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, GPO Box X2213, Perth, Western Australia 6847, Australia
    Food Funct 4:111-5. 2013
  4. doi request reprint Long-term effects of a protein-enriched diet on blood pressure in older women
    Jonathan M Hodgson
    Royal Perth Hospital Unit, School of Medicine and Pharmacology, University of Western Australia, GPO Box X2213, Perth, Western Australia 6847, Australia
    Br J Nutr 107:1664-72. 2012
  5. doi request reprint Tea flavonoids and cardiovascular health
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Mol Aspects Med 31:495-502. 2010
  6. doi request reprint Effects of increasing dietary protein and fibre intake with lupin on body weight and composition and blood lipids in overweight men and women
    J M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, and the WAIMR Centre for Food and Genomic Medicine, Perth, Western Australia, Australia
    Int J Obes (Lond) 34:1086-94. 2010
  7. ncbi request reprint Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects
    Jonathan M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, and the Western Australian Institute for Medical Research, Perth, Australia
    Br J Nutr 97:842-6. 2007
  8. ncbi request reprint Chocolate consumption and bone density in older women
    Jonathan M Hodgson
    Royal Perth Hospital Unit, the University of Western Australia School of Medicine and Pharmacology, Perth, Australia
    Am J Clin Nutr 87:175-80. 2008
  9. ncbi request reprint Effects of tea and tea flavonoids on endothelial function and blood pressure: a brief review
    J M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 33:838-41. 2006
  10. ncbi request reprint Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans
    Jonathan M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
    J Nutr 137:363-7. 2007

Detail Information

Publications60

  1. doi request reprint Relationships of vascular function with measures of ambulatory blood pressure variation
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, GPO Box X2213 Perth, Western Australia 6847, Australia Electronic address
    Atherosclerosis 233:48-54. 2014
    ..Characteristics of short-term blood pressure (BP) variation may influence cardiovascular disease risk via effects on vascular function...
  2. doi request reprint Black tea lowers the rate of blood pressure variation: a randomized controlled trial
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 97:943-50. 2013
    ..The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated...
  3. doi request reprint Short-term effects of polyphenol-rich black tea on blood pressure in men and women
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, GPO Box X2213, Perth, Western Australia 6847, Australia
    Food Funct 4:111-5. 2013
    ..8) bpm, and -1.9 (95% CI, -3.7, -0.2) bpm, respectively; P < 0.05 for both), but not during the day-time. These results suggest that the longer-term benefits of black tea on blood pressure are unlikely to be due to short-term changes...
  4. doi request reprint Long-term effects of a protein-enriched diet on blood pressure in older women
    Jonathan M Hodgson
    Royal Perth Hospital Unit, School of Medicine and Pharmacology, University of Western Australia, GPO Box X2213, Perth, Western Australia 6847, Australia
    Br J Nutr 107:1664-72. 2012
    ..Therefore, the present study did not provide evidence that a higher whey protein intake in older women can have prolonged effects on blood pressure...
  5. doi request reprint Tea flavonoids and cardiovascular health
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Mol Aspects Med 31:495-502. 2010
    ..Data supporting reduced oxidative damage, inflammation, platelet activation, blood pressure, and risk of type 2 diabetes with tea (flavonoids) remains inadequate to draw any conclusions...
  6. doi request reprint Effects of increasing dietary protein and fibre intake with lupin on body weight and composition and blood lipids in overweight men and women
    J M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, and the WAIMR Centre for Food and Genomic Medicine, Perth, Western Australia, Australia
    Int J Obes (Lond) 34:1086-94. 2010
    ..In addition, several studies have suggested that lupin may reduce cholesterol concentrations and benefit glucose and insulin metabolism...
  7. ncbi request reprint Acute effects of tea on fasting and non-fasting plasma total homocysteine concentrations in human subjects
    Jonathan M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, and the Western Australian Institute for Medical Research, Perth, Australia
    Br J Nutr 97:842-6. 2007
    ..Given that results of population studies have generally shown a negative association between tea intake and tHcy, the significance of these findings to CVD risk remains uncertain...
  8. ncbi request reprint Chocolate consumption and bone density in older women
    Jonathan M Hodgson
    Royal Perth Hospital Unit, the University of Western Australia School of Medicine and Pharmacology, Perth, Australia
    Am J Clin Nutr 87:175-80. 2008
    ..Nutrition is important for the development and maintenance of bone structure and for the prevention of osteoporosis and fracture. The relation of chocolate intake with bone has yet to be investigated...
  9. ncbi request reprint Effects of tea and tea flavonoids on endothelial function and blood pressure: a brief review
    J M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 33:838-41. 2006
    ..5. Overall, the available data suggest that the effects of tea flavonoids on endothelial function and, perhaps, blood pressure may be responsible, at least in part, for any benefits of drinking tea on the risk of cardiovascular disease...
  10. ncbi request reprint Increased lean red meat intake does not elevate markers of oxidative stress and inflammation in humans
    Jonathan M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, Perth, Western Australia, Australia
    J Nutr 137:363-7. 2007
    ..4 (-3.4, 0.5) mg/L], and plasma fibrinogen concentrations [-0.08 (-0.40. 0.24) g/L]. Our results suggest that partial replacement of dietary carbohydrate with protein from lean red meat does not elevate oxidative stress or inflammation...
  11. doi request reprint Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
    R Belski
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Int J Obes (Lond) 35:810-9. 2011
    ..Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre...
  12. ncbi request reprint Acute effects of ingestion of black and green tea on lipoprotein oxidation
    J M Hodgson
    University of Western Australia, Department of Medicine, and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
    Am J Clin Nutr 71:1103-7. 2000
    ..The absence of effects in previous studies may be due to the isolation of LDL particles from polyphenolic compounds that are present in the aqueous phase of serum...
  13. doi request reprint Sesame supplementation does not improve cardiovascular disease risk markers in overweight men and women
    J H Y Wu
    School of Medicine and Pharmacology, University of Western Australia, PO Box X2213 GPO, Perth WA 6847, Australia
    Nutr Metab Cardiovasc Dis 19:774-80. 2009
    ..We aimed to investigate the effects of sesame supplementation in humans on blood lipids, blood pressure, systemic oxidative stress, inflammatory biomarkers and mammalian lignan metabolism...
  14. ncbi request reprint Recent developments concerning diet and hypertension
    L J Beilin
    University Department of Medicine, Royal Perth Hospital, University of Western Australia and HeartSearch WA, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 28:1078-82. 2001
    ..3. Regular coffee drinking raised blood pressure in older hypertensives, whereas potential antihypertensive effects of dietary anti-oxidants require further scrutiny...
  15. doi request reprint Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction
    Wai Mun Loke
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Arterioscler Thromb Vasc Biol 30:749-57. 2010
    ....
  16. ncbi request reprint Non pharmacologic therapy and lifestyle factors in hypertension
    L J Beilin
    Department of Medicine, University of Western Australia, Royal Perth Hospital, Australia
    Blood Press 10:352-65. 2001
    ....
  17. ncbi request reprint Dietary protein and soluble fiber reduce ambulatory blood pressure in treated hypertensives
    V Burke
    Department of Medicine, University of Western Australia, Royal Perth Hospital and West Australian Heart Research Institute, Perth, Australia
    Hypertension 38:821-6. 2001
    ..These findings have important implications for the prevention and management of hypertension, particularly in populations in which high blood pressure is prevalent in association with diets low in protein, fiber, or both...
  18. ncbi request reprint Effects of regular ingestion of black tea on haemostasis and cell adhesion molecules in humans
    J M Hodgson
    University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia
    Eur J Clin Nutr 55:881-6. 2001
    ..To assess the effects in humans of regular ingestion of black tea on haemostasis-related variables and cell adhesion molecules...
  19. ncbi request reprint Effects of alpha-tocopherol and mixed tocopherol supplementation on markers of oxidative stress and inflammation in type 2 diabetes
    Jason H Y Wu
    School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
    Clin Chem 53:511-9. 2007
    ....
  20. ncbi request reprint Supplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetes
    Michael W Clarke
    Department of Core Clinical Pathology and Biochemistry, Royal Perth Hospital, University of Western Australia, Perth, Australia
    Am J Clin Nutr 83:95-102. 2006
    ..Gamma-tocopherol, a major dietary form of vitamin E, may have protective properties different from those of alpha-tocopherol...
  21. ncbi request reprint Gallic acid metabolites are markers of black tea intake in humans
    J M Hodgson
    Department of Medicine, University of Western Australia, Royal Perth Hospital, Perth, Western Australia, Australia
    J Agric Food Chem 48:2276-80. 2000
    ..It is suggested that these compounds have the potential to be used as markers of black tea intake...
  22. ncbi request reprint Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
    Wai Mun Loke
    School of Medicine and Pharmacology and the School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Perth, Western Australia
    Am J Clin Nutr 88:1018-25. 2008
    ..Dietary flavonoids may improve endothelial function and ultimately lead to beneficial cardiovascular effects...
  23. ncbi request reprint Tea intake is inversely related to blood pressure in older women
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, Western Australia, Australia
    J Nutr 133:2883-6. 2003
    ..The observed associations for both tea intake and 4-O-methylgallic acid are consistent with the hypothesis that long-term regular ingestion of tea may have a favorable effect on blood pressure in older women...
  24. doi request reprint Vitamin E supplementation and hepatic drug metabolism in humans
    Michael W Clarke
    Department of Core Clinical Pathology and Biochemistry, PathWest Laboratory Medicine, Royal Perth Hospital, University of Western Australia, Perth, Western Australia, Australia
    J Cardiovasc Pharmacol 54:491-6. 2009
    ..These findings do not support the hypothesis that alpha-TOH supplementation interferes with hepatic CYP3A4-mediated drug metabolism...
  25. ncbi request reprint Isoflavonoids do not inhibit in vivo lipid peroxidation in subjects with high-normal blood pressure
    J M Hodgson
    University of Western Australia Department of Medicine and the Western Australian Heart Research Institute, Royal Perth Hospital, Australia
    Atherosclerosis 145:167-72. 1999
    ..These results are not consistent with the suggestion that the two soy derived isoflavonoids have in vivo antioxidant activity at a level of intake achievable by dietary means and in subjects with high-normal BP...
  26. ncbi request reprint Effects on blood pressure of drinking green and black tea
    J M Hodgson
    University of Western Australia Department of Medicine and the Western Australian Heart Research Institute, Royal Perth Hospital, Australia
    J Hypertens 17:457-63. 1999
    ....
  27. ncbi request reprint Effects of isoflavonoids on blood pressure in subjects with high-normal ambulatory blood pressure levels: a randomized controlled trial
    J M Hodgson
    University of Western Australia Department of Medicine, Royal Perth Hospital, Australia
    Am J Hypertens 12:47-53. 1999
    ..Therefore, these results do not support the hypothesis that isoflavonoids, and genistein in particular, are major contributors to the BP lowering effect of vegetarian diets...
  28. doi request reprint A single nucleotide polymorphism in the CYP4F2 but not CYP4A11 gene is associated with increased 20-HETE excretion and blood pressure
    Natalie C Ward
    Schools of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Hypertension 51:1393-8. 2008
    ..The positive association between the CYP4F2 GA/AA genotype and both systolic blood pressure and 20-hydroxyeicosatetraenoic acid excretion strengthens a role for 20-hydroxyeicosatetraenoic acid in the modulation of blood pressure...
  29. ncbi request reprint Tea flavonoids and cardiovascular disease
    Jonathan M Hodgson
    School of Medicine and Pharmacology, GPO Box X2213, Perth, WA, 6847, Australia
    Asia Pac J Clin Nutr 17:288-90. 2008
    ..Additional studies are needed to investigate whether regular consumption of tea can reduce blood pressure, inflammation and the risk of thrombosis. The evidence for benefit on oxidative damage and cholesterol reduction remains weak...
  30. doi request reprint Inhibition of 20-hydroxyeicosatetraenoic acid synthesis using specific plant lignans: in vitro and human studies
    Jason H Y Wu
    School of Medicine and Pharmacology, Royal Perth Hospital, University of Western Australia, Perth, Western Australia, Australia
    Hypertension 54:1151-8. 2009
    ..These results suggest that sesame lignans could be used for the investigation of potential roles of 20-HETE in humans...
  31. ncbi request reprint Urinary 20-hydroxyeicosatetraenoic acid excretion is associated with oxidative stress in hypertensive subjects
    Natalie C Ward
    School of Medicine and Pharmachology, University of Western Ausralia, Perth, Australia
    Free Radic Biol Med 38:1032-6. 2005
    ..In conclusion, the study highlights the positive association observed between 20-HETE excretion and markers of oxidative damage. The study also provides evidence that gamma-GT may be a useful marker of oxidative stress...
  32. doi request reprint A metabolite profiling approach to identify biomarkers of flavonoid intake in humans
    Wai Mun Loke
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, Perth, WA 6000, Australia
    J Nutr 139:2309-14. 2009
    ..Potential biomarkers of (-)-epicatechin were not identified. These urinary biomarkers may provide an accurate indication of flavonoid exposure...
  33. ncbi request reprint Regular ingestion of tea does not inhibit in vivo lipid peroxidation in humans
    Jonathan M Hodgson
    University of Western Australia, Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, WA 6001, Australia
    J Nutr 132:55-8. 2002
    ..These results do not support the suggestion that polyphenolic antioxidants derived from tea inhibit in vivo lipid peroxidation...
  34. doi request reprint Skim milk compared with a fruit drink acutely reduces appetite and energy intake in overweight men and women
    Emma R Dove
    School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia
    Am J Clin Nutr 90:70-5. 2009
    ..Several studies show that proteins, including whey and casein, are more satiating than carbohydrates. It follows that skim milk would be more satiating than sugar-rich beverages. However, this has yet to be shown...
  35. ncbi request reprint The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial
    Natalie C Ward
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Hypertens 25:227-34. 2007
    ..Our aim was to investigate the effect of alpha-tocopherol and gamma-tocopherol supplementation on 24-h ambulatory blood pressure (BP) and heart rate, vascular function and oxidative stress in individuals with type 2 diabetes...
  36. ncbi request reprint Lupin-enriched bread increases satiety and reduces energy intake acutely
    Ya P Lee
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 84:975-80. 2006
    ..Protein and fiber may be important determinants of satiety. Lupin kernel flour is a novel food ingredient that is rich in protein and fiber...
  37. ncbi request reprint The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial
    Natalie C Ward
    School of Medicine and Pharmacology, University of Western Australia and West Australian Institute for Medical Research WAIMR, Perth, Australia
    J Hypertens 23:427-34. 2005
    ..Thus, dietary antioxidants may beneficially influence blood pressure (BP) and endothelial function by reducing oxidative stress...
  38. ncbi request reprint Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, Western Australian Institute for Medical Research WAIMR, Royal Perth Hospital Unit, Perth, Western Australia
    J Hypertens 23:47-54. 2005
    ..Controlled trials in humans have found that ingestion of tea can improve endothelial function, but also cause a rapid onset acute increase in blood pressure...
  39. ncbi request reprint Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic Acid, an important metabolite of proanthocyanidins in humans
    Natalie C Ward
    School of Medicine and Pharmacology, University of Western Australia, and Western Australian Institute for Medical Research, Perth, Australia
    J Agric Food Chem 52:5545-9. 2004
    ..002). The observed increase in 3-HPP is in line with the suggestion that this compound is a major phenolic acid breakdown product of proanthocyanidin metabolism in vivo...
  40. ncbi request reprint Phenolic acid metabolites as biomarkers for tea- and coffee-derived polyphenol exposure in human subjects
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia
    Br J Nutr 91:301-6. 2004
    ....
  41. ncbi request reprint Oxidative stress in human hypertension: association with antihypertensive treatment, gender, nutrition, and lifestyle
    Natalie C Ward
    School of Medicine and Pharmacology, University of Western Australia, Western Australian Institute for Medical Research WAIMR, Perth, Australia
    Free Radic Biol Med 36:226-32. 2004
    ..The results do not support the hypothesis that treated or untreated hypertensive subjects are under increased oxidative stress compared with normotensive controls...
  42. ncbi request reprint Can black tea influence plasma total homocysteine concentrations?
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, and the Western Australian Institute for Medical Research, Royal Perth Hospital, Perth, Australia
    Am J Clin Nutr 77:907-11. 2003
    ..This may result in elevations in plasma total homocysteine (tHcy) concentrations after ingestion of polyphenol-rich beverages such as tea...
  43. ncbi request reprint Leukocyte count and vascular function in Type 2 diabetic subjects with treated hypertension
    Richard J Woodman
    Department of Medicine, The University of Western Australia and The West Australian Heart Research Institute, Royal Perth Hospital, Perth, Australia
    Atherosclerosis 163:175-81. 2002
    ..This study examined the associations between vascular function and markers of inflammation in Type 2 diabetic subjects with treated hypertension...
  44. ncbi request reprint Acute effects of ingestion of black tea on postprandial platelet aggregation in human subjects
    Jonathan M Hodgson
    University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Australia
    Br J Nutr 87:141-5. 2002
    ..The results of this study do not support the suggestion that reduced postprandial platelet aggregability contributes to any benefits of black tea on cardiovascular risk...
  45. ncbi request reprint Red wine and beer elevate blood pressure in normotensive men
    Renate R Zilkens
    School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Western Australian Institute for Medical Research, Perth, Western Australia
    Hypertension 45:874-9. 2005
    ....
  46. ncbi request reprint Regular ingestion of black tea improves brachial artery vasodilator function
    Jonathan M Hodgson
    Department of Medicine, University of Western Australia and HeartSearch, Royal Perth Hospital, G P O Box X2213, Perth, Western Australia 6847, Australia
    Clin Sci (Lond) 102:195-201. 2002
    ..These differences remained after adjustment for age, sex and body mass index. These results suggest that one mechanism by which black tea may reduce cardiovascular risk is via improved vasodilator function of conduit arteries...
  47. ncbi request reprint 20-Hydroxyeicosatetraenoic acid is not associated with circulating insulin in lean to overweight humans
    Natalie C Ward
    School of Medicine and Pharmacology RPH, University of Western Australia, Level 4, Rear 50 Murray Street, Perth, WA 6000, Australia
    Diabetes Res Clin Pract 74:197-200. 2006
    ..The results of the present study suggest that the observed positive association between urinary 20-HETE excretion and BMI may not be related to circulating insulin levels or insulin resistance...
  48. ncbi request reprint Drinking tea is associated with lower plasma total homocysteine in older women
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology, PO Box X2213, Perth, WA 6001, Australia
    Asia Pac J Clin Nutr 15:253-8. 2006
    ..The observed lower tHcy in women with higher tea intake is consistent in direction and magnitude with previous epidemiological studies, but any mechanisms remain unclear...
  49. ncbi request reprint Partial substitution of carbohydrate intake with protein intake from lean red meat lowers blood pressure in hypertensive persons
    Jonathan M Hodgson
    University of Western Australia, School of Medicine and Pharmacology at Royal Perth Hospital, GPO Box X2213, Perth, WA 6001, Australia
    Am J Clin Nutr 83:780-7. 2006
    ..Compared with carbohydrate intake, dietary intake of plant protein can lower blood pressure in humans, but the effects of animal protein intake on blood pressure have yet to be investigated...
  50. ncbi request reprint Is reversal of endothelial dysfunction by tea related to flavonoid metabolism?
    Jonathan M Hodgson
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Br J Nutr 95:14-7. 2006
    ..Thus, differences in flavonoid metabolism could be related to the level of benefit of dietary flavonoids on the risk of CVD...
  51. ncbi request reprint Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes
    J M Hodgson
    University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia
    Eur J Clin Nutr 56:1137-42. 2002
    ..Our objective was to assess effects of dietary supplementation with coenzyme Q10 (CoQ) on blood pressure and glycaemic control in subjects with type 2 diabetes, and to consider oxidative stress as a potential mechanism for any effects...
  52. doi request reprint Effects of lupin kernel flour-enriched bread on blood pressure: a controlled intervention study
    Ya P Lee
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    Am J Clin Nutr 89:766-72. 2009
    ..Available data suggest that substitution of refined carbohydrate in the diet with protein and fiber may benefit blood pressure. Lupin kernel flour is high in protein and fiber and low in carbohydrate...
  53. doi request reprint Protein, fibre and blood pressure: potential benefit of legumes
    Ya Ping Lee
    University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, University of Western Australia, Perth, Western Australia, Australia
    Clin Exp Pharmacol Physiol 35:473-6. 2008
    ..5. This review assesses the evidence for effects of protein and fibre to reduce blood pressure and the potential of incorporation of legumes into the daily diet as a feasible approach to achieving such benefits for blood pressure...
  54. ncbi request reprint Nitration of gamma-tocopherol prevents its oxidative metabolism by HepG2 cells
    Jason H Y Wu
    School of Medicine and Pharmacology, University of Western Australia, PO Box X2213, GPO Perth 6847, West Australia
    Free Radic Biol Med 39:483-94. 2005
    ..Whether 5-NO2-gammaT could be metabolised via other pathways in vivo requires further investigation...
  55. ncbi request reprint Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: lack of association between antioxidant and lipoxygenase inhibitory activity
    Wai Mun Loke
    School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
    Biochem Pharmacol 75:1045-53. 2008
    ....
  56. ncbi request reprint Can coenzyme Q10 improve vascular function and blood pressure? Potential for effective therapeutic reduction in vascular oxidative stress
    Jonathan M Hodgson
    University of Western Australia School of Medicine and Pharmacology and the Western Australian Institute for Medical Research, Royal Perth Hospital, Western Australia, Australia
    Biofactors 18:129-36. 2003
    ..The particularly relevant groups of patients for these studies are those with insulin resistance, type 2 diabetes, hypertension and the metabolic syndrome...
  57. doi request reprint Quercetin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation
    Wai Mun Loke
    School of Medicine and Pharmacology, University of Western Australia, Royal Perth Hospital Unit, Medical Research Foundation Building, Level 4, 50 Murray Street, Perth, WA 6000, Australia
    J Agric Food Chem 56:3609-15. 2008
    ..Dietary flavonoids that could modify MPO activity could protect lipoproteins from damage in chronic inflammatory states such as cardiovascular disease...
  58. ncbi request reprint Tea drinking is associated with benefits on bone density in older women
    Amanda Devine
    Nutrition Program, School of Exercise, Biomedical and Health Science, Edith Cowan University, 100 Joondalup Drive, Joondalup WA 6027 Australia
    Am J Clin Nutr 86:1243-7. 2007
    ..Impaired hip structure assessed by dual-energy X-ray absorptiometry (DXA) areal bone mineral density (aBMD) is an independent predictor for osteoporotic hip fracture. Some studies suggest that tea intake may protect against bone loss...
  59. ncbi request reprint Dietary fibre and blood pressure
    Jonathan M Hodgson
    J Hypertens 22:25-6. 2004
  60. ncbi request reprint Dietary flavonoids and cardiovascular disease: does the emperor have any clothes?
    Jonathan M Hodgson
    J Hypertens 23:1461-3. 2005