M P Hitchins

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. doi request reprint The role of epigenetics in Lynch syndrome
    Megan P Hitchins
    Adult Cancer Program, Medical Epigenetics Laboratory, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Randwick, NSW, Australia
    Fam Cancer 12:189-205. 2013
  2. doi request reprint Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer
    M P Hitchins
    Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
    J Med Genet 46:793-802. 2009
  3. doi request reprint Alu in Lynch syndrome: a danger SINE?
    Megan P Hitchins
    Medical Epigenetics Laboratory, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Cancer Prev Res (Phila) 4:1527-30. 2011

Collaborators

Detail Information

Publications3

  1. doi request reprint The role of epigenetics in Lynch syndrome
    Megan P Hitchins
    Adult Cancer Program, Medical Epigenetics Laboratory, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Randwick, NSW, Australia
    Fam Cancer 12:189-205. 2013
    ..This review charts the discovery of mismatch repair epimutations, their aetiological role in Lynch syndrome and the mechanistic basis for their variable inheritance patterns. ..
  2. doi request reprint Constitutional (germline) MLH1 epimutation as an aetiological mechanism for hereditary non-polyposis colorectal cancer
    M P Hitchins
    Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
    J Med Genet 46:793-802. 2009
    ..The molecular characteristics, clinical ramifications and potential mechanism underlying this defect are discussed. Recommendations for the selection of cases warranting screening for MLH1 epimutations are proffered...
  3. doi request reprint Alu in Lynch syndrome: a danger SINE?
    Megan P Hitchins
    Medical Epigenetics Laboratory, Lowy Cancer Research Centre, Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Cancer Prev Res (Phila) 4:1527-30. 2011
    ..Whether Alu density is a danger sign for genomic regions prone to rearrangement and what additional factors may be required to actuate these events remain to be discovered...