Ian B Hickie

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi Protocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder
    Helen Christensen
    Centre for Mental Health Research, The Australian National University, Canberra, Australia
    Trials 11:48. 2010
  2. ncbi Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
  3. ncbi Fatigue states after cancer treatment occur both in association with, and independent of, mood disorder: a longitudinal study
    David Goldstein
    Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
    BMC Cancer 6:240. 2006
  4. ncbi Practitioner-supported delivery of internet-based cognitive behaviour therapy: evaluation of the feasibility of conducting a cluster randomised trial
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Med J Aust 192:S31-5. 2010
  5. ncbi Commentary on 'Evaluating treatments for the mood disorders: time for the evidence to get real'
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Rozelle, New South Wales, Australia
    Aust N Z J Psychiatry 38:415-8. 2004
  6. ncbi Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, 100 Mallett Street, Camperdown, NSW 2050, Australia
    J Affect Disord 98:137-42. 2007
  7. ncbi Mental health expenditure in Australia: time for affirmative action
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, New South Wales
    Aust N Z J Public Health 30:119-22. 2006
  8. ncbi Perspectives of young people on depression: awareness, experiences, attitudes and treatment preferences
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Camperdown, Sydney, New South Wales, Australia
    Early Interv Psychiatry 1:333-9. 2007
  9. ncbi General practitioners' response to depression and anxiety in the Australian community: a preliminary analysis
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, NSW 2039, Australia
    Med J Aust 181:S15-20. 2004
  10. ncbi Is real reform of the Medicare Benefits Schedule for psychiatrists in Australia economically, socially or professionally desirable?
    Ian Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Australas Psychiatry 14:8-14. 2006

Collaborators

Detail Information

Publications128 found, 100 shown here

  1. ncbi Protocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder
    Helen Christensen
    Centre for Mental Health Research, The Australian National University, Canberra, Australia
    Trials 11:48. 2010
    ..This study aims to determine the effectiveness of a web-based program for treating GAD relative to sertraline and attention placebo...
  2. ncbi Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
    ..The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV) infection...
  3. ncbi Fatigue states after cancer treatment occur both in association with, and independent of, mood disorder: a longitudinal study
    David Goldstein
    Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
    BMC Cancer 6:240. 2006
    ..We sought to examine the longitudinal relationships between fatigue and mood disorder in women treated with adjuvant therapy for early stage breast cancer...
  4. ncbi Practitioner-supported delivery of internet-based cognitive behaviour therapy: evaluation of the feasibility of conducting a cluster randomised trial
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Med J Aust 192:S31-5. 2010
    ..To determine the feasibility of conducting a cluster randomised trial in Australia of the effectiveness of general practitioner-supported delivery of internet-based cognitive behaviour therapy (CBT) and enhanced psychological care...
  5. ncbi Commentary on 'Evaluating treatments for the mood disorders: time for the evidence to get real'
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Rozelle, New South Wales, Australia
    Aust N Z J Psychiatry 38:415-8. 2004
  6. ncbi Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, 100 Mallett Street, Camperdown, NSW 2050, Australia
    J Affect Disord 98:137-42. 2007
    ....
  7. ncbi Mental health expenditure in Australia: time for affirmative action
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, New South Wales
    Aust N Z J Public Health 30:119-22. 2006
    ..Urgent investments in cost-effective modes of care are required and these should prioritise increased access among those subpopulations disadvantaged by other social, economic or geographic factors...
  8. ncbi Perspectives of young people on depression: awareness, experiences, attitudes and treatment preferences
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Camperdown, Sydney, New South Wales, Australia
    Early Interv Psychiatry 1:333-9. 2007
    ..Ascertaining current knowledge and attitudes towards depression among young people is vital for developing campaigns promoting community awareness and early intervention...
  9. ncbi General practitioners' response to depression and anxiety in the Australian community: a preliminary analysis
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, NSW 2039, Australia
    Med J Aust 181:S15-20. 2004
    ....
  10. ncbi Is real reform of the Medicare Benefits Schedule for psychiatrists in Australia economically, socially or professionally desirable?
    Ian Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Australas Psychiatry 14:8-14. 2006
    ..To propose alternative Medicare Benefits Schedule-based funding models for outpatient psychiatric services in Australia...
  11. ncbi Reducing the burden of depression: are we making progress in Australia?
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, PO Box M160, Camperdown, NSW 1450, Australia
    Med J Aust 181:S4-5. 2004
  12. ncbi Can we track the impact of Australian mental health research?
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, New South Wales, Australia
    Aust N Z J Psychiatry 39:591-9. 2005
    ..Specifically, we describe the research output of nations, Australian states, Australian and New Zealand institutions and Australian and New Zealand researchers using citation rates...
  13. ncbi Australian mental health reform: time for real outcomes
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, PO Box M160, Camperdown, NSW 2050, Australia
    Med J Aust 182:401-6. 2005
    ..New independent and national reporting systems on the progress of mental health reform are urgently required...
  14. ncbi Surveying perceptions of the progress of national mental health reform
    Ian Hickie
    Brain and Mind Research Institute, PO Box M160, Camperdown, NSW 1450, Australia
    Australas Psychiatry 12:123-5. 2004
    ..A national, government-supported system needs to be developed in order to monitor progress of genuine mental health reform in Australia...
  15. ncbi Vascular risk and low serum B12 predict white matter lesions in patients with major depression
    Ian Hickie
    Brain and Mind Research Institute, University of Sydney, P O Box M160, Missenden Road NSW 2050, Australia Beyondblue The National Depression Initiative, VIC Australia
    J Affect Disord 85:327-32. 2005
    ..While patients with depression have been shown to have a greater incidence of vascular risk factors and structural brain changes, any association with dietary co-factors is unclear...
  16. ncbi Treatment guidelines for depression in the Asia Pacific region: a review of current developments
    Ian Hickie
    Brain and Mind Research Institute, PO Box M160, Camperdown, NSW 1450, Australia
    Australas Psychiatry 12:S33-7. 2004
    ..This paper examines the development of treatment guidelines, medication algorithms and clinical pathway guides for depression in countries participating in the SEBoD Initiative...
  17. ncbi Can we reduce the burden of depression? The Australian experience with beyondblue: the national depression initiative
    Ian Hickie
    Brain and Mind Research Institute, PO Box M160, Camperdown, NSW 1450, Australia
    Australas Psychiatry 12:S38-46. 2004
    ..This paper describes the development and early achievements of the Australian depression initiative, beyondblue...
  18. ncbi Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression
    Ian Hickie
    Brain and Mind Research Institute, PO Box M160, Missenden Road, NSW Australia
    Br J Psychiatry 186:197-202. 2005
    ..Hippocampal volume reduction has been reported inconsistently in people with major depression...
  19. ncbi Psychomotor slowing in older patients with major depression: Relationships with blood flow in the caudate nucleus and white matter lesions
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Psychiatry Res 155:211-20. 2007
    ..Reduced %rCBF is associated with demonstrable psychomotor slowing and presence of WMLs. While psychomotor slowing is determined in part by subcortical changes, other cortical and illness-dependent factors are likely to be relevant...
  20. ncbi Increased access to evidence-based primary mental health care: will the implementation match the rhetoric?
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Med J Aust 187:100-3. 2007
    ..The responsibility for achieving the best outcome does not lie only with governments. To date, the professions have not placed enough emphasis on systematically adopting evidence-based forms of collaborative care...
  21. ncbi Is depression overdiagnosed? No
    Ian Hickie
    Brain and Mind Research Institute, University of Sydney, Camperdown, NSW 2050, Sydney, Australia
    BMJ 335:329. 2007
  22. ncbi Managing depression across the life cycle: new strategies for clinicians and their patients
    I B Hickie
    Brain and Mind Research Institute, University of Sydney, Camperdown, New South Wales, Australia
    Intern Med J 39:720-7. 2009
    ....
  23. ncbi Are common childhood or adolescent infections risk factors for schizophrenia and other psychotic disorders?
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW
    Med J Aust 190:S17-21. 2009
    ..This pathophysiological path should be investigated more systematically as it may explain a novel "neuroprotective" mode of action for some existing antipsychotic compounds...
  24. ncbi The assessment of depression awareness and help-seeking behaviour: experiences with the International Depression Literacy Survey
    Ian B Hickie A M
    Brain and Mind Research Institute, The University of Sydney, Sydney, Australia
    BMC Psychiatry 7:48. 2007
    ..The International Depression Literacy Survey (IDLS) has been developed to assess understanding of depression in different cultural and health care settings...
  25. ncbi Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and health-care settings?
    Ian Hickie
    Brain and Mind Research Institute, Camperdown, NSW, Australia
    Aust N Z J Psychiatry 43:25-35. 2009
    ..The subjects had fatigue lasting 1-6 months (prolonged fatigue), or >6 months (chronic fatigue), or met diagnostic criteria for chronic fatigue syndrome...
  26. ncbi Responding to experiences of young people with common mental health problems attending Australian general practice
    Ian B Hickie
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Med J Aust 187:S47-52. 2007
    ..Improved access to specific psychological treatments should remain a priority...
  27. ncbi Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis cluster
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    J Psychiatry Neurosci 37:313-21. 2012
    ..Further research is warranted to determine whether patients with bipolar-spectrum disorders show similar impairments in these biomarkers...
  28. ncbi Reduced mismatch negativity in mild cognitive impairment: associations with neuropsychological performance
    Loren Mowszowski
    Ageing Brain Centre, Brain and Mind Research Institute, The University of Sydney, 94 Mallett Street, Camperdown, NSW 2050, Australia
    J Alzheimers Dis 30:209-19. 2012
    ..These findings overall suggest that MMN may be a viable neurophysiological biomarker of underlying disease in this 'at risk' group...
  29. ncbi Neuropsychological performance in patients with depression is associated with clinical, etiological and genetic risk factors
    Sharon L Naismith
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Clin Exp Neuropsychol 25:866-77. 2003
    ..These findings underscore the need to consider subtypes when investigating neuropsychological deficits in patients with depression...
  30. ncbi Reduced temporal mismatch negativity in late-life depression: an event-related potential index of cognitive deficit and functional disability?
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Australia
    J Affect Disord 138:71-8. 2012
    ..This study examined MMN elicited by duration deviant stimuli in older people with lifetime depression, and explored its relationship with neuropsychological functioning and disability...
  31. ncbi Impaired MMN/P3a complex in first-episode psychosis: cognitive and psychosocial associations
    Daniel F Hermens
    Clinical Research Unit, Brain and Mind Research Institute, The University of Sydney, Sydney, Australia
    Prog Neuropsychopharmacol Biol Psychiatry 34:822-9. 2010
    ..Such deficits in FEP appear to have important links with higher-order cognitive and psychosocial functioning...
  32. ncbi Sleep disturbance relates to neuropsychological functioning in late-life depression
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, Australia
    J Affect Disord 132:139-45. 2011
    ..Sleep-wake disturbance in older people is a risk factor for depression onset and recurrence. The aim of this study was to determine if objective sleep-wake disturbance in late-life depression relates to neuropsychological functioning...
  33. ncbi Correlating anterior insula gray matter volume changes in young people with clinical and neurocognitive outcomes: an MRI study
    Sean N Hatton
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    BMC Psychiatry 12:45. 2012
    ..This study examined the relationship between anterior insula GMV, clinical symptom severity and neuropsychological performance in a heterogeneous cohort of young people presenting for mental health care...
  34. ncbi Targeted primary care-based mental health services for young Australians
    Elizabeth M Scott
    Clinical Research Unit, Brain and Mind Research Institute, Sydney, NSW
    Med J Aust 196:136-40. 2012
    ....
  35. ncbi Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial
    Nicole L Cockayne
    Brain and Mind Research Institute, The University of Sydney, Camperdown NSW, Australia
    BMC Psychiatry 11:10. 2011
    ....
  36. ncbi Fronto-striatal correlates of impaired implicit sequence learning in major depression: an fMRI study
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    J Affect Disord 125:256-61. 2010
    ..This study sought to probe the integrity of fronto-striatal circuits using functional magnetic resonance imaging (fMRI) in conjunction with a theoretically-driven motor sequencing implicit learning (IL) task...
  37. ncbi MMN/P3a deficits in first episode psychosis: comparing schizophrenia-spectrum and affective-spectrum subgroups
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Schizophr Res 130:203-9. 2011
    ..First-episode psychosis (FEP) patients show reduced amplitudes of the 'MMN/P3a complex', but it is unclear whether this occurs across the FEP spectrum...
  38. ncbi Recognition and treatment of depression: a comparison of Australian and Chinese medical students
    Ye Rong
    Brain and Mind Research Institute, The University of Sydney, Camperdown NSW 2050, Australia
    Soc Psychiatry Psychiatr Epidemiol 44:636-42. 2009
    ..To improve services, we need to ensure health professionals have an appropriate understanding of depression and its treatments. This study compares the level of awareness of depression between Chinese and Australian medical students...
  39. ncbi The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features
    Sharon L Naismith
    Ageing Brain Centre, Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Prog Neurobiol 98:99-143. 2012
    ..Ultimately, future research must aim to evaluate whether basic biomedical knowledge can be successfully translated into enhanced health outcomes via the implementation of early intervention paradigms...
  40. ncbi Does sleep disturbance mediate neuropsychological functioning in older people with depression?
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 94 Mallet Street, Camperdown NSW 2050, Australia
    J Affect Disord 116:139-43. 2009
    ..However, the association between sleep disturbance and neuropsychological functioning in depression has not been well evaluated. The current study therefore aimed to investigate these relationships...
  41. ncbi Cognitive training in affective disorders improves memory: a preliminary study using the NEAR approach
    Sharon L Naismith
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    J Affect Disord 121:258-62. 2010
    ..Some of these changes persist despite antidepressant treatment. While research in other areas of psychiatry has shown cognitive training techniques to be effective, only one study has evaluated this approach in depression...
  42. ncbi Neuropsychological clustering highlights cognitive differences in young people presenting with depressive symptoms
    Daniel F Hermens
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    J Int Neuropsychol Soc 17:267-76. 2011
    ..Distinct neuropsychological profiling may help to predict later psychiatric outcomes and enhance individually-tailored early intervention strategies...
  43. ncbi Can older "at risk" adults benefit from psychoeducation targeting healthy brain aging?
    Louisa M Norrie
    Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    Int Psychogeriatr 23:413-24. 2011
    ..The current study sought to investigate whether older adults "at risk" of cognitive decline benefit from psychoeducation targeting healthy brain aging...
  44. ncbi Impaired verbal memory in young adults with unipolar and bipolar depression
    Daniel F Hermens
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, New South Wales, Australia
    Early Interv Psychiatry 4:227-33. 2010
    ..Specifically, deficits in verbal memory have been linked to depression in young people. This study examined whether young adults with unipolar compared with bipolar depression showed similar neurocognitive deficits...
  45. ncbi Frontal lobe changes occur early in the course of affective disorders in young people
    Jim Lagopoulos
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    BMC Psychiatry 12:4. 2012
    ..Contrasts were carried out between controls subjects and patients cohorts with attenuated syndromes and discrete disorders, separately...
  46. ncbi Sleep well, think well: sleep-wake disturbance in mild cognitive impairment
    Sharon L Naismith
    Ageing Brain Centre, Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    J Geriatr Psychiatry Neurol 23:123-30. 2010
    ..This preliminary data suggests that sleep-wake disturbance in nonamnestic forms of MCI is related to cognitive functioning and may be indicative of shared neurobiological underpinnings...
  47. ncbi Early intervention for cognitive decline: is there a role for multiple medical or behavioural interventions?
    Sharon L Naismith
    Brain and Mind Research Institute, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Early Interv Psychiatry 3:19-27. 2009
    ..Evidence for the beneficial effects of providing relevant interventions is assessed...
  48. ncbi Impaired implicit sequence learning in depression: a probe for frontostriatal dysfunction?
    Sharon L Naismith
    Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Psychol Med 36:313-23. 2006
    ..Consequently, it is ideally suited for testing elements of the frontostriatal model of major depression and performance can be related to key clinical, neuropsychological, vascular and biochemical data...
  49. ncbi Microstructural white matter changes in the corpus callosum of young people with Bipolar Disorder: a diffusion tensor imaging study
    Jim Lagopoulos
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
    PLoS ONE 8:e59108. 2013
    ..Our findings provide evidence of microstructural white matter changes early in the course of illness within the corpus callosum and the nature of these changes suggest they are associated with abnormalities in the myelination of axons...
  50. ncbi Applying clinical staging to young people who present for mental health care
    Ian B Hickie
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health Centre for Youth Mental Health, University of Melbourne Orygen Youth Health Research Centre, Melbourne, Victoria, Australia School of Psychology, University of Birmingham, Edgbaston, UK
    Early Interv Psychiatry 7:31-43. 2013
    ..Conclusion: Among young people presenting for mental health care, most are clinically staged as having 'attenuated syndromes'. Despite access to specialized treatment, a significant number progress to more severe or persistent disorders...
  51. ncbi Thoughts of death or suicidal ideation are common in young people aged 12 to 30 years presenting for mental health care
    Elizabeth M Scott
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
    BMC Psychiatry 12:234. 2012
    ..This study determines the socio-demographic, psychopathological and illness-stage correlates of suicidal ideation in young persons attending headspace services...
  52. ncbi Alcohol use and mismatch negativity in young patients with psychotic disorder
    Kate M Chitty
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Neuroreport 22:918-22. 2011
    ..This may reflect an additive effect of N-methyl-D-aspartate receptor hypofunction and high-alcohol consumption...
  53. ncbi The impact of gender on early ill-health retirement in people with heart disease and depression
    Matt B Paradise
    Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
    Aust N Z J Psychiatry 46:249-56. 2012
    ..Given the deleterious effects of ill-health retirement, identifying at-risk groups is important for guiding targeted interventions...
  54. ncbi Improving knowledge and attitudes towards depression: a controlled trial among Chinese medical students
    Ye Rong
    Brain and Mind Research Institute, The University of Sydney, Sydney, Australia
    BMC Psychiatry 11:36. 2011
    ..The purpose of this study was to determine whether a self-directed learning strategy as a part of student-centred education improved knowledge of and attitudes towards depression among Chinese medical students...
  55. ncbi The role of mild depression in sleep disturbance and quality of life in Parkinson's disease
    Sharon L Naismith
    Brain and Mind Research Institute, University of Sydney, Camperdown, New South Wales, Australia
    J Neuropsychiatry Clin Neurosci 22:384-9. 2010
    ..Overall, these data highlight the need to screen patients for even mild levels of depression because its relationship with sleep and quality of life are evident early in the disease course...
  56. ncbi Enhancing memory in late-life depression: the effects of a combined psychoeducation and cognitive training program
    Sharon L Naismith
    Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, NSW, Australia
    Am J Geriatr Psychiatry 19:240-8. 2011
    ..To evaluate the efficacy of a multifactorial cognitive training (CT) program for older people with a lifetime history of depressive disorder...
  57. ncbi Disability is already pronounced in young people with early stages of affective disorders: data from an early intervention service
    Blake A Hamilton
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, 2050 Australia
    J Affect Disord 131:84-91. 2011
    ..This study examined patient self-reported disability in young people attending a designated early intervention service...
  58. ncbi Neuropsychological and socio-occupational functioning in young psychiatric outpatients: a longitudinal investigation
    Rico S C Lee
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    PLoS ONE 8:e58176. 2013
    ..The current study extended these findings to young and early-course psychiatric outpatients, with the aim of identifying cognitive markers that predict later socio-occupational functioning...
  59. ncbi Delayed preattentional functioning in early psychosis patients with cannabis use
    Nicole Pesa
    School of Psychology, University of Wollongong, Wollongong, NSW, 2522, Australia
    Psychopharmacology (Berl) 222:507-18. 2012
    ..The event-related potentials, mismatch negativity (MMN) and P3a are reduced in EP. Cannabinoids have been shown to modulate N-methyl-D-aspartate receptors which are involved in MMN generation...
  60. ncbi Arginine Vasopressin selectively enhances recognition of sexual cues in male humans
    Adam J Guastella
    Brain and Mind Research Institute, University of Sydney, Camperdown, Sydney, NSW, Australia
    Psychoneuroendocrinology 36:294-7. 2011
    ..They further extend animal and human genetic studies linking Arginine Vasopressin to sexual behavior in males. Findings suggest an important cognitive mechanism that could enhance sexual behaviors in humans...
  61. ncbi A systematic review of the impact of adherence on the effectiveness of e-therapies
    Liesje Donkin
    Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
    J Med Internet Res 13:e52. 2011
    ..Understanding the role of adherence may be crucial to understanding how program usage influences the effectiveness of e-therapy interventions...
  62. ncbi How does social functioning in the early stages of psychosis relate to depression and social anxiety?
    Catherine Chudleigh
    Clinical Research Unit, Brain and Mind Research Institute, New South Wales, Australia
    Early Interv Psychiatry 5:224-32. 2011
    ....
  63. ncbi Making new choices about antidepressants in Australia: the long view 1975-2002
    Andrea Mant
    Quality Use of Medicines, South East Health, Sydney Hospital, PO Box 1614, Sydney, NSW 2001, Australia
    Med J Aust 181:S21-4. 2004
    ..To examine trends in types of antidepressant medications prescribed in Australia between 1975 and 2002...
  64. ncbi Clinical staging model applied to young people presenting with social anxiety
    Patrick J F Clarke
    Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales, Australia
    Early Interv Psychiatry 6:256-64. 2012
    ..The goal was to provide a detailed description of common clinical stage of those presenting for treatment of social anxiety, and to delineate the associations between symptom type, severity and clinical stage...
  65. ncbi Mismatch negativity/P3a complex in young people with psychiatric disorders: a cluster analysis
    Manreena Kaur
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    PLoS ONE 7:e51871. 2012
    ..A data driven approach may help to further elucidate novel patterns of MMN/P3a amplitudes that characterise distinct subgroups in patients with emerging psychiatric disorders...
  66. ncbi Distinguishing young people with emerging bipolar disorders from those with unipolar depression
    Elizabeth M Scott
    Clinical Research Unit, Brain and Mind Research Institute, University of Sydney, 100 Mallet Street, Camperdown, NSW 2050, Australia
    J Affect Disord 144:208-15. 2013
    ..To facilitate early intervention, there is a need to distinguish unipolar versus bipolar illness trajectories in adolescents and young adults with adult-type mood disorders...
  67. ncbi Disability in major depression related to self-rated and objectively-measured cognitive deficits: a preliminary study
    Sharon L Naismith
    Brain and Mind Research Institute, University of Sydney, Camperdown, Australia
    BMC Psychiatry 7:32. 2007
    ..This study examined the relationships between self-rated disability in persons with MD and both self-rated and objectively-measured cognitive functioning...
  68. ncbi The relationship between actigraphically defined sleep disturbance and REM sleep behaviour disorder in Parkinson's Disease
    Sharon L Naismith
    Parkinson s Disease Research Clinic, Ageing Brain Centre, Brain and Mind Research Institute, University of Sydney, 94 Mallett St, Camperdown, NSW 2050, Australia
    Clin Neurol Neurosurg 112:420-3. 2010
    ..In this study, we sought to evaluate the utility of actigraphy for examining symptoms of rapid eye movement sleep behaviour disorder (RSBD)...
  69. ncbi What can alert the general practitioner to people whose common mental health problems are unrecognised?
    Kay A Wilhelm
    Consultation Liaison Psychiatry, St Vincent s Hospital, Sydney, NSW, Australia
    Med J Aust 188:S114-8. 2008
    ..To assess the characteristics of people with common mental health problems who are recognised by their general practitioner, and those who are not...
  70. ncbi Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders
    Adam J Guastella
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW 2050, Australia
    Biol Psychiatry 67:692-4. 2010
    ..Deficits in the ability to recognize the emotions of others are believed to contribute to this. There is currently no effective treatment for these problems...
  71. ncbi Effect of oral appliance therapy on neurobehavioral functioning in obstructive sleep apnea: a randomized controlled trial
    Sharon L Naismith
    Department of Respiratory and Sleep Medicine, St George Hospital, The University of New South Wales, Sydney, Australia
    J Clin Sleep Med 1:374-80. 2005
    ..This study aimed to assess the efficacy of a custom-made mandibular advancement splint for the treatment of obstructive sleep apnea with respect to neuropsychological functioning and mood state...
  72. ncbi Novel melatonin-based therapies: potential advances in the treatment of major depression
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Camperdown, NSW, Australia
    Lancet 378:621-31. 2011
    ..As agomelatine does not raise serotonin levels, it has less potential for the common gastrointestinal, sexual, or metabolic side-effects that characterise many other antidepressant compounds...
  73. ncbi Psychological morbidity in women at increased risk of developing breast cancer: a controlled study
    Phyllis Butow
    Medical Psychology Research Unit, University of Sydney, Australia
    Psychooncology 14:196-203. 2005
    ..These results refute the hypothesis that women with a family history of breast cancer are at greater psychological risk...
  74. ncbi Facilitating early intervention: experiences of young people and implications for the shaping of headspace services
    Sharon Medlow
    Brain and Mind Research Institute, University of Sydney, Camperdown, NSW, Australia
    Australas Psychiatry 18:335-9. 2010
    ..The aim of this study was to gain an understanding of the factors that facilitate entry of young people into the Australian mental health care system with a view to developing headspace service delivery in youth-friendly directions...
  75. ncbi Youth mental health: we know where we are and we can now say where we need to go next
    Ian B Hickie
    Brain and Mind Research Institute, The University of Sydney, Camperdown, Australia
    Early Interv Psychiatry 5:63-9. 2011
    ..To provide an overview of the state of knowledge relevant to the development of youth-specific mental health initiatives...
  76. ncbi Were the budgetary reforms to the Better Access to Mental Health Care initiative appropriate?--no
    Sebastian Rosenberg
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW sebastian rosenbergATsydney edu au
    Med J Aust 194:595. 2011
    ..Mental health policy expert Sebastian Rosenberg and psychiatrist Ian Hickie want more change...
  77. ncbi Effect of sertraline on symptoms and survival in patients with advanced cancer, but without major depression: a placebo-controlled double-blind randomised trial
    Martin R Stockler
    NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia
    Lancet Oncol 8:603-12. 2007
    ..We aimed to identify the effects of an established antidepressant on these symptoms and survival in patients with advanced cancer who did not have major depression as assessed by clinicians...
  78. ncbi Subjective memory complaints, vascular risk factors and psychological distress in the middle-aged: a cross-sectional study
    Matt B Paradise
    Brain and Mind Research Institute, The University of Sydney, Camperdown, NSW 2050, Australia
    BMC Psychiatry 11:108. 2011
    ..We therefore aimed to test the hypothesis that vascular risk factors were associated with SMC, independent of psychological distress, in a middle-aged community-dwelling population...
  79. ncbi Intranasal arginine vasopressin enhances the encoding of happy and angry faces in humans
    Adam J Guastella
    Brain and Mind Research Institute, University of Sydney, Sydney, Australia
    Biol Psychiatry 67:1220-2. 2010
    ..There has been little research in humans exploring its effect on social cognition, including the encoding of social memories...
  80. ncbi Providing psychological treatments in general practice: how will it work?
    Grant Blashki
    c Psychiatry Research Unit, PO Box 1, Rozelle, NSW 2039, Australia
    Med J Aust 179:23-5. 2003
    ..Research focusing on GP training and how GPs interact with specialist services in the provision of psychological treatments is urgently required...
  81. ncbi Measuring outcomes in patients with depression or anxiety: an essential part of clinical practice
    Ian B Hickie
    School of Psychiatry, University of New South Wales at St George Hospital, Sydney, NSW
    Med J Aust 177:205-7. 2002
    ..As depression and anxiety are relapsing or chronic conditions and are often comorbid with other medical conditions, standard outcome measures should be incorporated into the management plans for all such patients...
  82. ncbi Therapeutic signposts: using biomarkers to guide better treatment of schizophrenia and other psychotic disorders
    Richard Banati
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW
    Med J Aust 190:S26-32. 2009
    ..A specific example of the use of a novel positron emission tomography marker of progressive brain disease in patients with schizophrenia is described...
  83. ncbi Amphetamine psychosis: a model for studying the onset and course of psychosis
    Daniel F Hermens
    Brain and Mind Research Institute, University of Sydney, Sydney, NSW
    Med J Aust 190:S22-5. 2009
    ..It is possible that the same approach may be used in young people known to be at risk of schizophrenia and related disorders, by informing models that involve other environmental or genetic risks...
  84. ncbi Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression
    Sharon Naismith
    School of Psychiatry, University of New South Wales, PO Box 1, Rozelle NSW 2039, Sydney, Australia
    Am J Psychiatry 159:2096-8. 2002
    ..The authors sought to determine whether caudate nucleus volumes or specific genotypes predict psychomotor slowing in older persons with depression...
  85. ncbi More us than them: positive depictions of mental illness on Australian television news
    Connie Henson
    School of Public Health, University of Sydney, Sydney, NSW, Australia
    Aust N Z J Psychiatry 43:554-60. 2009
    ....
  86. ncbi Vascular risk to late-life depression: evidence from a longitudinal community study
    Ian Hickie
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Aust N Z J Psychiatry 37:62-5. 2003
    ..To determine prospectively relationships between minor cerebrovascular episodes and depressive symptoms in a community cohort of older persons...
  87. ncbi Neurasthenia: prevalence, disability and health care characteristics in the Australian community
    Ian Hickie
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Br J Psychiatry 181:56-61. 2002
    ..Neurasthenia imposes a high burden on primary medical health care systems in all societies...
  88. ncbi Electroconvulsive therapy-induced persistent retrograde amnesia: could it be minimised by ketamine or other pharmacological approaches?
    Emily M Gregory-Roberts
    Brain and Mind Research Institute, University of Sydney, Australia
    J Affect Disord 126:39-45. 2010
    ..This review examines mechanisms for electroconvulsive therapy-induced retrograde amnesia, and evaluates the suitability of the anaesthetic ketamine for preventing this amnestic outcome...
  89. ncbi Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study
    Ian Hickie
    Brain and Mind Research Institute, Sydney University, Sydney, NSW 2050, Australia
    BMJ 333:575. 2006
    ..Post-infective fatigue syndrome is a valid illness model for investigating one pathophysiological pathway to chronic fatigue syndrome...
  90. ncbi Australia needs a mental health commission
    Alan Rosen
    Comprehensive Area Service Psychiatrists Group, Sydney, NSW, Australia
    Australas Psychiatry 12:213-9. 2004
    ..It could also promote and advise formally on enhancing community awareness, decreasing stigma and discrimination and improving workforce recruitment and retention...
  91. ncbi The brain and mind research institute: a unique campus for the integration of clinical and basic neurosciences in Australia
    Ian Hickie
    Brain and Mind Research Institute, NSW, Camperdown, Australia
    Australas Psychiatry 16:169-72. 2008
    ..The aim of this paper is to describe the conceptual and practical development of the Brain and Mind Research Institute (BMRI) at the University of Sydney...
  92. ncbi Concurrent validity of the PSYCH-6, a very short scale for detecting anxiety and depression, among oncology outpatients
    Kerrie Clover
    Faculty of Health, Psycho Oncology Service, Calvary Mater, School of Medical Practice and Population Health, University of Newcastle, NSW, Australia
    Aust N Z J Psychiatry 43:682-8. 2009
    ..This study examined the concurrent validity of a relatively new, very short scale, the six item PSYCH-6 subscale of the Somatic and Psychological Health Report (SPHERE-12), in an oncology outpatient population...
  93. ncbi Delivering youth-specific mental health services: the advantages of a collaborative, multi-disciplinary system
    Elizabeth Scott
    The Clinical Centre, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Australas Psychiatry 17:189-94. 2009
    ..The development of such services has proceeded on the basis of limited service-based data and has also been impeded by current healthcare funding structures...
  94. ncbi The experience of cancer-related fatigue and chronic fatigue syndrome: a qualitative and comparative study
    Barbara Bennett
    Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia
    J Pain Symptom Manage 34:126-35. 2007
    ..Qualitatively, CRF appears closely related to CFS. These findings raise the emergent hypothesis of a conserved neurobehavioral symptom complex, which results from diverse triggering insults...
  95. ncbi The neglect of somatoform disorders by old age psychiatry: some explanations and suggestions for future research
    Chanaka Wijeratne
    St George Hospital, NSW, Australia
    Int J Geriatr Psychiatry 18:812-9. 2003
    ..The somatoform disorders have long been ignored by old age psychiatry. The main aim of this paper is to identify and examine possible reasons for this neglect...
  96. ncbi Measurement of EBV-IgG anti-VCA avidity aids the early and reliable diagnosis of primary EBV infection
    Peter Robertson
    Serology Laboratory, SEALS, Prince of Wales Hospital, Randwick, New South Wales, Australia
    J Med Virol 70:617-23. 2003
    ..The combination of negative IgG anti-EBNA and low-avidity IgG anti-VCA had a sensitivity and specificity of 100%. The routine addition of IgG anti-VCA avidity estimation to diagnostic EBV serology is recommended...
  97. ncbi Room for improvement: mixed portrayal of young people with mental illness on Australian television news
    Connie Henson
    School of Public Health, University of Sydney, Sydney, NSW 2006, Australia
    Aust N Z J Psychiatry 44:267-72. 2010
    ..The aim of the present study was to review television news depiction of mental illness in children and adolescents to test the hypothesis that positive portrayals of adults with mental illness also apply to young people...
  98. ncbi Gene expression correlates of postinfective fatigue syndrome after infectious mononucleosis
    Barbara Cameron
    School of Medical Sciences, University of New South Wales, Sydney, Australia
    J Infect Dis 196:56-66. 2007
    ..Infectious mononucleosis (IM) commonly triggers a protracted postinfective fatigue syndrome (PIFS) of unknown pathogenesis...
  99. ncbi Postinfective fatigue syndrome is not associated with altered cytokine production
    Ute Vollmer-Conna
    School of Psychiatry, University of New South Wales, Sydney University, Sydney, Australia
    Clin Infect Dis 45:732-5. 2007
    ..No significant differences were found. Ongoing production of the cytokines examined does not play a role in postinfective fatigue syndrome...
  100. ncbi The characteristics of fatigue in an older primary care sample
    Chanaka Wijeratne
    St George Hospital, New South Wales, Australia
    J Psychosom Res 62:153-8. 2007
    ..This has led to considerable debate about whether fatigue may present independently of psychological disorder. Somatic symptoms in older people have been assumed to be almost entirely physical in origin...
  101. ncbi headspace: Australia's National Youth Mental Health Foundation--where young minds come first
    Patrick D McGorry
    University of Melbourne, Melbourne, Vic, Australia
    Med J Aust 187:S68-70. 2007
    ....