Corinna Van Den Heuvel

Summary

Affiliation: University of Adelaide
Country: Australia

Publications

  1. ncbi request reprint Magnesium in acute and chronic brain injury: an update
    Robert Vink
    Discipline of Pathology, School of Medical Sciences, University of Adelaide, Australia
    Magnes Res 22:158S-162S. 2009
  2. doi request reprint sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide South Australia, Australia
    J Neurochem 122:208-20. 2012
  3. doi request reprint Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide, SA 5005, Australia
    Neurosci Lett 515:50-4. 2012
  4. pmc Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage
    Naomi L Cook
    Discipline of Anatomy and Pathology, School of Medical Sciences, The University of Adelaide, Adelaide, SA 5005, Australia
    BMC Mol Biol 11:7. 2010
  5. ncbi request reprint Downregulation of amyloid precursor protein (APP) expression following post-traumatic cyclosporin-A administration
    Corinna Van Den Heuvel
    Department of Pathology, University of Adelaide, Adelaide, South Australia, Australia
    J Neurotrauma 21:1562-72. 2004
  6. ncbi request reprint Traumatic brain injury and Alzheimer's disease: a review
    Corinna Van Den Heuvel
    Discipline of Pathology, University of Adelaide, Centre for Neurological Diseases, The Hanson Institute, Adelaide, Australia
    Prog Brain Res 161:303-16. 2007
  7. ncbi request reprint Magnesium gluconate offers no more protection than magnesium sulphate following diffuse traumatic brain injury in rats
    Renee J Turner
    Department of Pathology, University of Adelaide, Adelaide, SA, Australia
    J Am Coll Nutr 23:541S-544S. 2004
  8. doi request reprint Transient receptor potential melastatin 2 expression is increased following experimental traumatic brain injury in rats
    Naomi L Cook
    Discipline of Anatomy and Pathology, The University of Adelaide, Adelaide, Australia
    J Mol Neurosci 42:192-9. 2010
  9. ncbi request reprint The role of magnesium in traumatic brain injury
    Corinna Van Den Heuvel
    Department of Pathology, University of Adelaide
    Clin Calcium 14:9-14. 2004
  10. doi request reprint The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, South Australia, Australia
    Brain Res 1378:137-43. 2011

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Magnesium in acute and chronic brain injury: an update
    Robert Vink
    Discipline of Pathology, School of Medical Sciences, University of Adelaide, Australia
    Magnes Res 22:158S-162S. 2009
    ..Taken together, a more complete picture is emerging of the role of magnesium in brain injury, its therapeutic potential as well the mechanisms associated with its decline...
  2. doi request reprint sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide South Australia, Australia
    J Neurochem 122:208-20. 2012
    ..Importantly, it indicates that the mechanism of action of exogenously added sAPPα is independent of the presence of endogenous APP...
  3. doi request reprint Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide, SA 5005, Australia
    Neurosci Lett 515:50-4. 2012
    ....
  4. pmc Reference genes for normalising gene expression data in collagenase-induced rat intracerebral haemorrhage
    Naomi L Cook
    Discipline of Anatomy and Pathology, School of Medical Sciences, The University of Adelaide, Adelaide, SA 5005, Australia
    BMC Mol Biol 11:7. 2010
    ..Reference gene panels have therefore been proposed to overcome this potential confounder...
  5. ncbi request reprint Downregulation of amyloid precursor protein (APP) expression following post-traumatic cyclosporin-A administration
    Corinna Van Den Heuvel
    Department of Pathology, University of Adelaide, Adelaide, South Australia, Australia
    J Neurotrauma 21:1562-72. 2004
    ..0% in CyA-treated impacted animals, 5.5% in untreated nonimpacted animals, and 6% in CyA-treated non-impacted controls. These results demonstrate that CyA has a downregulatory effect on increased APP expression caused by TBI...
  6. ncbi request reprint Traumatic brain injury and Alzheimer's disease: a review
    Corinna Van Den Heuvel
    Discipline of Pathology, University of Adelaide, Centre for Neurological Diseases, The Hanson Institute, Adelaide, Australia
    Prog Brain Res 161:303-16. 2007
    ..Furthermore, although it is known that APOE genotype plays an important role in AD, its link to a deleterious outcome following TBI remains inconclusive and ambiguous...
  7. ncbi request reprint Magnesium gluconate offers no more protection than magnesium sulphate following diffuse traumatic brain injury in rats
    Renee J Turner
    Department of Pathology, University of Adelaide, Adelaide, SA, Australia
    J Am Coll Nutr 23:541S-544S. 2004
    ..We have therefore compared the efficacy of both MgSO(4) and magnesium gluconate (MgGl(2)) on outcome following diffuse TBI in rats...
  8. doi request reprint Transient receptor potential melastatin 2 expression is increased following experimental traumatic brain injury in rats
    Naomi L Cook
    Discipline of Anatomy and Pathology, The University of Adelaide, Adelaide, Australia
    J Mol Neurosci 42:192-9. 2010
    ..Further characterisation of how TRPM2 may contribute to TBI pathophysiology is warranted...
  9. ncbi request reprint The role of magnesium in traumatic brain injury
    Corinna Van Den Heuvel
    Department of Pathology, University of Adelaide
    Clin Calcium 14:9-14. 2004
    ..This brief review will summarize the experimental evidence supporting a critical role of Mg(2+) in the pathophysiology of TBI, and will examine the use of magnesium salts as a therapeutic intervention...
  10. doi request reprint The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains
    Frances Corrigan
    Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, South Australia, Australia
    Brain Res 1378:137-43. 2011
    ..As the D1 and D6a domains contain a heparin binding region while the D2 domain does not, this suggests that sAPPα mediates its neuroprotective response through its ability to bind to heparin sulfate proteoglycans...
  11. doi request reprint Validation of reference genes for normalization of real-time quantitative RT-PCR data in traumatic brain injury
    Naomi L Cook
    Discipline of Pathology, The University of Adelaide, Adelaide, South Australia, Australia
    J Neurosci Res 87:34-41. 2009
    ..The use of the most stable reference genes presented here will allow more accurate normalization of gene expression data in TBI...
  12. doi request reprint Are the transient receptor potential melastatin (TRPM) channels important in magnesium homeostasis following traumatic brain injury?
    Naomi L Cook
    Discipline of Pathology, School of Medical Sciences, The University of Adelaide, Australia
    Magnes Res 22:225-34. 2009
    ..The purpose of this review is to explore the relationship between TRPM family members and Mg(2+) homeostasis, including their potential involvement in secondary injury processes leading to cell death following TBI...
  13. ncbi request reprint Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat
    Liqun Yang
    Department of Surgery Neurosurgery, Institute of Medical and Veterinary Science, Adelaide, SA, Australia
    J Clin Neurosci 12:276-84. 2005
    ....
  14. ncbi request reprint Amiloride increases neuronal damage after traumatic brain injury in rats
    Renee J Turner
    Department of Pathology, University of Adelaide, Adelaide, SA, Australia
    J Am Coll Nutr 23:534S-537S. 2004
    ..An alternative to administration of Mg salts may be to prevent cellular loss of Mg with use of amiloride, which inhibits the Na(+)/Mg(2+) exchange...
  15. ncbi request reprint Recent advances in the development of multifactorial therapies for the treatment of traumatic brain injury
    Robert Vink
    The University of Adelaide, Department of Pathology, Level 3, Medical School North, Adelaide, SA 5005, Australia
    Expert Opin Investig Drugs 13:1263-74. 2004
    ..This review will focus on three such novel compounds that are currently being assessed in clinical trials; progesterone, dexanabinol and dexamethasone, and provide an update on the progress of both magnesium and cyclosporin A...
  16. doi request reprint Substance P antagonists as a therapeutic approach to improving outcome following traumatic brain injury
    Robert Vink
    School of Medical Sciences, University of Adelaide, Adelaide, South Australia, Australia
    Neurotherapeutics 7:74-80. 2010
    ..This review summarizes the current evidence supporting a role for substance P in acute brain injury...
  17. doi request reprint Intracranial pressure changes following traumatic brain injury in rats: lack of significant change in the absence of mass lesions or hypoxia
    Levon Gabrielian
    School of Medical Sciences, Adelaide Centre for Neurological Diseases, University of Adelaide, Adelaide SA, Australia
    J Neurotrauma 28:2103-11. 2011
    ..Therefore, they are an inappropriate model for the investigation of ICP changes after TBI, and for the development of therapies targeting ICP...
  18. ncbi request reprint Soluble amyloid precursor protein alpha reduces neuronal injury and improves functional outcome following diffuse traumatic brain injury in rats
    Emma Thornton
    Department of Pathology Level 3, Medical School North, The University of Adelaide South Australia, Australia 5005
    Brain Res 1094:38-46. 2006
    ..Promotion of APP processing toward sAPPalpha may thus be a novel therapeutic strategy in the treatment of TBI...