Research Topics
| John HawkinsSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Detecting and sorting targeting peptides with neural networks and support vector machinesJohn Hawkins
School of Information Technology and Electrical Engineering, The University of Queensland, QLD 4072, Australia
J Bioinform Comput Biol 4:1-18. 2006..873 for non-plant and 0.849 for plant proteins. The model improves upon the accuracy of our previous subcellular localization predictor (PProwler v1.1) by 2% for plant data (which represents 7.5% improvement upon TargetP)...
The applicability of recurrent neural networks for biological sequence analysisJohn Hawkins
School of Information Technology and Electrical Engineering, University of Queensland, QLD 4072, Australia
IEEE/ACM Trans Comput Biol Bioinform 2:243-53. 2005..Furthermore, as the patterns within the sequence become more ambiguous, the choice of specific recurrent architecture becomes more critical...
Predicting nuclear localizationJohn Hawkins
ARC Centre for Complex Systems, School of Information Technology and Electrical Engineering, University of Queensland, QLD 4072, Australia
J Proteome Res 6:1402-9. 2007..The final predictor NUCLEO operates with a realistic success rate of 0.70 and a correlation coefficient of 0.38, as established on the independent test set. (NUCLEO is available at: http://pprowler.itee.uq.edu.au.)...
Identifying novel peroxisomal proteinsJohn Hawkins
ARC Centre for Complex Systems, The University of Queensland, St Lucia, Queensland 4072, Australia
Proteins 69:606-16. 2007..We use the predictor to screen several additional eukaryotic genomes to revise previously estimated numbers of peroxisomal proteins. Available at http://pprowler.itee.uq.edu.au...
Prediction of subcellular localization using sequence-biased recurrent networksMikael Boden
School of Information Technology and Electrical Engineering, The University of Queensland, QLD 4072, Australia
Bioinformatics 21:2279-86. 2005..However, due to the low similarity of such sequences and the dynamical nature of the sorting process, the computational prediction of subcellular localization of proteins is challenging...
Assessing phylogenetic motif models for predicting transcription factor binding sitesJohn Hawkins
Institute for Molecular Bioscience, University of Queensland, QLD, Australia
Bioinformatics 25:i339-47. 2009..Among the three scanning algorithms that we test, the MONKEY algorithm has the highest accuracy for predicting yeast TFBSs...
Improved access to sequential motifs: a note on the architectural bias of recurrent networksMikael Boden
IEEE Trans Neural Netw 16:491-4. 2005..and Hammer and Tino--offers superior access to motifs (sequential patterns) compared to the, in bioinformatics, standardly used feedforward neural networks...
