Research Topics
| Keith GrimwoodSummaryAffiliation: University of Queensland Country: Australia Publications
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Detail Information
Publications
Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocolAnne B Chang
Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
Trials 12:94. 2011..Our study tests the hypothesis that the anti-microbial and anti-inflammatory properties of azithromycin, improve the clinical outcomes of Indigenous Australian infants hospitalised with bronchiolitis...
Airway microbiology and host defences in paediatric non-CF bronchiectasisKeith Grimwood
Queensland Paediatric Infectious Diseases Laboratory, Queensland Children s Medical Research Institute, The University of Queensland, Royal Children s Hospital, Brisbane, Queensland, Australia
Paediatr Respir Rev 12:111-8. 2011..Airway inflammatory responses are excessive and persist, even once infection is cleared. Improved specimen collection, molecular techniques and biomarkers are needed to enhance management...- Rotavirus infections and vaccines: burden of illness and potential impact of vaccinationKeith Grimwood
Queensland Paediatric Infectious Diseases Laboratory, Queensland Children s Medical Research Institute, The University of Queensland, Royal Children s Hospital, Herston Road, Herston, QLD 4029, Australia
Paediatr Drugs 12:235-56. 2010..Nonetheless, cost effectiveness in each country still depends largely on the local rotavirus mortality rate and the price of the vaccine in relation to the per capita gross domestic product... - Effect of bronchoalveolar lavage-directed therapy on Pseudomonas aeruginosa infection and structural lung injury in children with cystic fibrosis: a randomized trialClaire E Wainwright
Queensland Children s Medical Research Institute, and Queensland Children s Respiratory Centre, Royal Children s Hospital, University of Queensland, Brisbane, Australia
JAMA 306:163-71. 2011..While bronchoalveolar lavage (BAL) is an alternative diagnostic tool, evidence for its clinical benefit is lacking... - Clonal complex Pseudomonas aeruginosa in horsesTimothy J Kidd
Department of Infectious Diseases, Royal Children s Hospital, Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, Australia
Vet Microbiol 149:508-12. 2011..Instead, other potential acquisition pathways, as well as strain specific adaptation to the equine genital tract, should be investigated... - Comparison of three molecular techniques for typing Pseudomonas aeruginosa isolates in sputum samples from patients with cystic fibrosisTimothy J Kidd
Queensland Paediatric Infectious Diseases Laboratory, Department of Infectious Diseases, Royal Children s Hospital, Queensland Children s Medical Research Institute, The University of Queensland, Brisbane, QLD, Australia
J Clin Microbiol 49:263-8. 2011..aeruginosa. Its focus on highly conserved housekeeping genes is particularly suited for long-term clinical monitoring and detecting novel strains... - Acute and persistent diarrheaKeith Grimwood
Queensland Paediatric Infectious Diseases Laboratory, Queensland Children s Medical Research Institute, Royal Children s Hospital, Herston Road, Herston, Brisbane, Queensland 4029, Australia
Pediatr Clin North Am 56:1343-61. 2009.... 
Chronic suppurative lung disease and bronchiectasis in children and adults in Australia and New ZealandAnne B Chang
Royal Children s Hospital and Queensland Children s Medical Research Institute, Brisbane, QLD, Australia
Med J Aust 193:356-65. 2010..Individualised long-term use of oral or nebulised antibiotics, corticosteroids, bronchodilators and mucoactive agents may provide a benefit, but are not recommended routinely...- Lower airway microbiology and cellularity in children with newly diagnosed non-CF bronchiectasisNitin Kapur
Department of Respiratory Medicine, Royal Children s Hospital, Brisbane, Queensland, Australia
Pediatr Pulmonol 47:300-7. 2012..Infection and inflammation are important in the pathogenesis of bronchiectasis. However, there are few published data describing the lower airway microbiology and cellularity in children... - Rotavirus vaccines: opportunities and challengesKeith Grimwood
Queensland Paediatric Infectious Diseases Laboratory, Sir Albert Sakzewski Virus Research Centre, Royal Children s Hospital, University of Queensland, Brisbane, Australia
Hum Vaccin 5:57-69. 2009..Nevertheless, if these challenges are met, rotavirus vaccines should help reduce the 5% of all childhood deaths attributable to rotavirus gastroenteritis... - Pentavalent rotavirus vaccine and prevention of gastroenteritis hospitalizations in AustraliaEmma J Field
Communicable Diseases Branch, Queensland Health, Brisbane, Queensland, Australia
Pediatrics 126:e506-12. 2010..We sought to assess vaccine effectiveness (VE) of 3 doses of RV5 at preventing rotavirus and nonrotavirus acute gastroenteritis (AGE) hospitalizations in the first birth cohort and impact on hospitalizations in all age groups... - Pseudomonas aeruginosa exhibits frequent recombination, but only a limited association between genotype and ecological settingTimothy J Kidd
Queensland Paediatric Infectious Diseases Laboratory, Queensland Children s Medical Research Institute, Royal Children s Hospital, The University of Queensland, Brisbane, Queensland, Australia
PLoS ONE 7:e44199. 2012..aeruginosa population. The increased abundance of some CF strains in different geographical regions is a likely product of chance colonisation events followed by adaptation to the CF lung and horizontal transmission among patients... - Flexible bronchoscopy in managing a child with pulmonary hydatid diseaseChristopher Burgess
Department of Respiratory Medicine, Royal Children s Hospital, Brisbane, Queensland, Australia
Pediatr Pulmonol 47:1140-2. 2012..This child did not require thoracic surgery and made a full clinical recovery, demonstrating that in selected cases FB may offer curative treatment... - Early evidence for direct and indirect effects of the infant rotavirus vaccine program in QueenslandStephen B Lambert
Queensland Paediatric Infectious Diseases Laboratory, Royal Children s Hospital, and Discipline of Paediatrics and Child Health, University of Queensland, Brisbane, QLD, Australia
Med J Aust 191:157-60. 2009..To assess the impact of introducing a publicly funded infant rotavirus vaccination program on disease notifications and on laboratory testing and results... - Human rotavirus vaccines: too early for the strain to tellKeith Grimwood
Queensland Paediatric Infectious Disease Laboratory, Discipline of Paediatrics and Child Health, Royal Children's Hospital and University of Queensland, Brisbane, QLD 4029, Australia
Lancet 371:1144-5. 2008 - Comparison of DNA extraction methods for microbial community profiling with an application to pediatric bronchoalveolar lavage samplesDana Willner
Australian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences and Institute of Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia
PLoS ONE 7:e34605. 2012..This study should help guide researchers to formulate sampling, extraction and analysis strategies for respiratory and other human microbiome samples... - Management of bronchiectasis and chronic suppurative lung disease in indigenous children and adults from rural and remote Australian communitiesAnne B Chang
Department of Respiratory Medicine, Royal Children s Hospital, Brisbane, QLD
Med J Aust 189:386-93. 2008..Physiotherapy and exercise should be encouraged, nutrition optimised, environmental pollutants (including tobacco smoke) avoided, and immunisations maintained... - Safety of bronchoalveolar lavage in young children with cystic fibrosisClaire E Wainwright
Department of Respiratory Medicine, Royal Children s Hospital, Brisbane, Australia
Pediatr Pulmonol 43:965-72. 2008..Our aim was to determine the safety of BAL in young children <6 years with CF... - Community-associated methicillin-resistant Staphylococcus aureus causing orbital cellulitis in Australian childrenVikram L Vaska
The University of Queensland, UQ Centre for Clinical Research, Herston, QLD, Australia
Pediatr Infect Dis J 30:1003-6. 2011..At a tertiary pediatric hospital in Brisbane, Australia, community-associated methicillin-resistant S. aureus orbital cellulitis was first noted in 2009. Since then, it has caused 4 of 9 such infections... - Low rates of Pseudomonas aeruginosa misidentification in isolates from cystic fibrosis patientsTimothy J Kidd
School of Medicine, University of Queensland, Brisbane, Queensland, Australia
J Clin Microbiol 47:1503-9. 2009..aeruginosa isolates. Isolates exhibiting atypical phenotypic features should be evaluated further by additional phenotypic or genotypic identification techniques... - Rotavirus vaccines must perform in low-income countries tooKeith Grimwood
Queensland Paediatric Infectious Disease Laboratory, Royal Children's Hospital, Department of Paediatrics and Child Health, University of Queensland, Brisbane, QLD 4029, Australia
Lancet 370:1739-40. 2007