Judith M Greer

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. doi request reprint Myelin proteolipid protein: an effective autoantigen and target of autoimmunity in multiple sclerosis
    Judith M Greer
    School of Medicine, The University of Queensland, Brisbane, QLD 4072, Australia
    J Autoimmun 31:281-7. 2008
  2. ncbi request reprint Correlation of blood T cell and antibody reactivity to myelin proteins with HLA type and lesion localization in multiple sclerosis
    Judith M Greer
    Neuroimmunology Research Unit, School of Medicine, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Queensland, Australia
    J Immunol 180:6402-10. 2008
  3. doi request reprint Role of gender in multiple sclerosis: clinical effects and potential molecular mechanisms
    Judith M Greer
    The University of Queensland, UQ Centre for Clinical Research, Royal Brisbane and Women s Hospital, Brisbane, 4029, Australia
    J Neuroimmunol 234:7-18. 2011
  4. doi request reprint An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population
    Attila L Szvetko
    Genomics Research Centre, Griffith Institute for Health and Medical Research, School of Medical Science, Griffith University, Gold Coast Campus, PMB50 GCMC Qld 9726, Queensland, Australia
    Brain Res 1255:148-52. 2009
  5. doi request reprint Frequency and function of regulatory T cells after ischaemic stroke in humans
    Jun Yan
    The University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia
    J Neuroimmunol 243:89-94. 2012
  6. ncbi request reprint Effect of gender on T-cell proliferative responses to myelin proteolipid protein antigens in patients with multiple sclerosis and controls
    Judith M Greer
    Neuroimmunology Research Centre, School of Medicine, The University of Queensland, Australia
    J Autoimmun 22:345-52. 2004
  7. doi request reprint CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia
    Amanda L Jones
    The University of Queensland, UQ Centre for Clinical Research, Brisbane, QLD 4029, Australia
    Brain Behav Immun 23:347-50. 2009
  8. ncbi request reprint Immunology of multiple sclerosis
    Michael P Pender
    Neuroimmunology Research Centre, Clinical Sciences Building, Royal Brisbane and Womens Hospital, Herston, Queensland 4029, Australia
    Curr Allergy Asthma Rep 7:285-92. 2007
  9. ncbi request reprint Studies of HLA associations in male and female patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
    Pamela A McCombe
    Neuroimmunology Research Centre, School of Medicine, The University of Queensland, Brisbane, Australia
    J Neuroimmunol 180:172-7. 2006
  10. ncbi request reprint Increased circulating T cell reactivity to GM1 ganglioside in patients with Guillain-Barré syndrome
    Peter A Csurhes
    Department of Medicine, The University of Queensland, Brisbane, Australia
    J Clin Neurosci 12:409-15. 2005

Collaborators

Detail Information

Publications23

  1. doi request reprint Myelin proteolipid protein: an effective autoantigen and target of autoimmunity in multiple sclerosis
    Judith M Greer
    School of Medicine, The University of Queensland, Brisbane, QLD 4072, Australia
    J Autoimmun 31:281-7. 2008
    ....
  2. ncbi request reprint Correlation of blood T cell and antibody reactivity to myelin proteins with HLA type and lesion localization in multiple sclerosis
    Judith M Greer
    Neuroimmunology Research Unit, School of Medicine, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Queensland, Australia
    J Immunol 180:6402-10. 2008
    ..These findings show that circulating T cells and Abs reactive against specific myelin Ags can correlate with lesion distribution in MS and suggest that they are of pathogenic relevance...
  3. doi request reprint Role of gender in multiple sclerosis: clinical effects and potential molecular mechanisms
    Judith M Greer
    The University of Queensland, UQ Centre for Clinical Research, Royal Brisbane and Women s Hospital, Brisbane, 4029, Australia
    J Neuroimmunol 234:7-18. 2011
    ..These include sex-specific differences between the male and female immune systems and nervous systems, genetic and epigenetic or environmental-related effects, the effects of gonadal hormones, and materno-fetal interactions...
  4. doi request reprint An investigation of the C77G and C772T variations within the human protein tyrosine phosphatase receptor type C gene for association with multiple sclerosis in an Australian population
    Attila L Szvetko
    Genomics Research Centre, Griffith Institute for Health and Medical Research, School of Medical Science, Griffith University, Gold Coast Campus, PMB50 GCMC Qld 9726, Queensland, Australia
    Brain Res 1255:148-52. 2009
    ....
  5. doi request reprint Frequency and function of regulatory T cells after ischaemic stroke in humans
    Jun Yan
    The University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia
    J Neuroimmunol 243:89-94. 2012
    ..This study is the first to report gender-specific changes in the numbers and function of Tregs after ischaemic stroke. These changes may affect stroke outcome...
  6. ncbi request reprint Effect of gender on T-cell proliferative responses to myelin proteolipid protein antigens in patients with multiple sclerosis and controls
    Judith M Greer
    Neuroimmunology Research Centre, School of Medicine, The University of Queensland, Australia
    J Autoimmun 22:345-52. 2004
    ..We suggest that this may be relevant to the higher prevalence of MS in women...
  7. doi request reprint CTLA-4 single-nucleotide polymorphisms in a Caucasian population with schizophrenia
    Amanda L Jones
    The University of Queensland, UQ Centre for Clinical Research, Brisbane, QLD 4029, Australia
    Brain Behav Immun 23:347-50. 2009
    ..These results suggest a role for the 3' UTR SNP and/or variants in high linkage disequilibrium with this SNP in the pathogenesis of schizophrenia...
  8. ncbi request reprint Immunology of multiple sclerosis
    Michael P Pender
    Neuroimmunology Research Centre, Clinical Sciences Building, Royal Brisbane and Womens Hospital, Herston, Queensland 4029, Australia
    Curr Allergy Asthma Rep 7:285-92. 2007
    ....
  9. ncbi request reprint Studies of HLA associations in male and female patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)
    Pamela A McCombe
    Neuroimmunology Research Centre, School of Medicine, The University of Queensland, Brisbane, Australia
    J Neuroimmunol 180:172-7. 2006
    ..This suggests that sex-related factors may interact with the risk associated with carriage of HLA-DR2 for development of CIDP...
  10. ncbi request reprint Increased circulating T cell reactivity to GM1 ganglioside in patients with Guillain-Barré syndrome
    Peter A Csurhes
    Department of Medicine, The University of Queensland, Brisbane, Australia
    J Clin Neurosci 12:409-15. 2005
    ..We suggest that T cell reactivity to gangliosides might play a contributory role in the pathogenesis of GBS and perhaps CIDP...
  11. doi request reprint Immune activation in the peripheral blood of patients with acute ischemic stroke
    Jun Yan
    The University of Queensland, Centre for Clinical Research, Brisbane, Australia
    J Neuroimmunol 206:112-7. 2009
    ..There was also an increase in the percentage of CCR7+ T cells. There were no significant differences in the activation of other cell types. In conclusion, there is evidence of immune activation and Treg cells in acute ischaemic stroke...
  12. pmc Interleukin-6 gene promoter-572 C allele may play a role in rate of disease progression in multiple sclerosis
    Jun Yan
    The University of Queensland, Centre for Clinical Research, Royal Brisbane and Women s Hospital, 4029 Brisbane, Australia
    Int J Mol Sci 13:13667-79. 2012
    ..Interestingly, however, the -572 C allele showed a significant correlation with the MS severity score, suggesting a possible role in disease progression...
  13. pmc The effect of ageing on human lymphocyte subsets: comparison of males and females
    Jun Yan
    The University of Queensland, UQ Centre for Clinical Research, Royal Brisbane and Women s Hospital, Brisbane, Australia
    Immun Ageing 7:4. 2010
    ..CONCLUSION: The cause of the change in percentage of lymphocyte subsets with age, and the different effects on males and females is not fully understood but warrants further study...
  14. ncbi request reprint Blood-brain barrier disruption and lesion localisation in experimental autoimmune encephalomyelitis with predominant cerebellar and brainstem involvement
    Diane M Muller
    Neuroimmunology Research Centre, The University of Queensland, Clinical Sciences Building, Royal Brisbane and Women s Hospital, Herston, Brisbane Q4029, Australia
    J Neuroimmunol 160:162-9. 2005
    ..Irrespective of the clinical type, the BBB was disrupted in the cerebellum and brainstem. Pertussis toxin had no effect on lesion distribution. Thus, lesion distribution is not influenced solely by BBB permeability...
  15. ncbi request reprint Myelin proteolipid protein--the first 50 years
    Judith M Greer
    Department of Medicine, The University of Queensland, Brisbane, Clinical Sciences Building, Royal Brisbane Hospital, 4029, QLD, Herston, Australia
    Int J Biochem Cell Biol 34:211-5. 2002
    ..However, recent molecular biology advances have given new life to investigations of PLP, and suggest that it has multiple functions within myelin and is of importance in several neurological disorders...
  16. ncbi request reprint Immune dysregulation and self-reactivity in schizophrenia: do some cases of schizophrenia have an autoimmune basis?
    Amanda L Jones
    Neuroimmunology Research Centre, School of Medicine, The University of Queensland, Brisbane, Australia
    Immunol Cell Biol 83:9-17. 2005
    ..Recent findings regarding specific autoimmune responses directed against neurotransmitter receptors in the brain in patients with schizophrenia will also be reviewed...
  17. ncbi request reprint Chemokines and chemokine receptors: potential therapeutic targets in multiple sclerosis
    Diane M Muller
    Neuroimmunology Research Centre, The University of Queensland, C Floor, Clinical Sciences Building, Royal Brisbane Hospital, Herston, Australia 4029
    Curr Drug Targets Inflamm Allergy 3:279-90. 2004
    ....
  18. pmc Gene expression in the spinal cord in female lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic protein
    Hayley R Inglis
    University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia
    PLoS ONE 7:e48555. 2012
    ..EAE induced in the Lewis with myelin basic protein (MBP-EAE) is well characterised, making it an ideal candidate for the analysis of gene expression in this disease model...
  19. doi request reprint Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability
    Jun Yan
    UQ Centre for Clinical Research, The University of Queensland, Australia
    J Neuroimmunol 246:78-84. 2012
    ..There was only a modest effect of stroke severity on levels of IL-6. There was also variability among individuals...
  20. ncbi request reprint Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis
    Michael P Pender
    Department of Medicine, The University of Queensland, Queensland, Australia
    J Clin Neurosci 10:63-6. 2003
    ..These findings suggest that ganglioside-specific T cells may contribute to the axonal damage in primary progressive MS...
  21. doi request reprint Female reproductive issues in multiple sclerosis
    Pamela A McCombe
    The University of Queensland Centre for Clinical Research, Royal Brisbane and Women s Hospital, Herston, QLD 4029, Australia
    Mult Scler 19:392-402. 2013
    ..The strong biological effect of pregnancy on MS deserves further study, so that these mechanisms can possibly be replicated as therapies for MS...
  22. pmc The role of epigenetic mechanisms and processes in autoimmune disorders
    Judith M Greer
    The University of Queensland, UQ Centre for Clinical Research, Brisbane, Queensland, Australia
    Biologics 6:307-27. 2012
    ..Increasing our knowledge of these epigenetic mechanisms and processes will increase the prospects for controlling or preventing autoimmune diseases in the future through the use of drugs that target the epigenetic pathways...
  23. ncbi request reprint Route of uptake of palmitoylated encephalitogenic peptides of myelin proteolipid protein by antigen-presenting cells: importance of the type of bond between lipid chain and peptide and relevance to autoimmunity
    Nadège A Pfender
    Chimie Organique des Substances Naturelles, Unite Mixte de Recherche 7177, Centre National de la Recherche Scientifique Université Louis Pasteur, Strasbourg, France
    J Immunol 180:1398-404. 2008
    ..These findings have implications for vaccine development and for the development of MHC class II-restricted autoimmune diseases, as many human autoantigens thus far identified are thioacylated...