Jason Grebely

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales UNSW, Sydney, Australia
    AIDS 26:1653-61. 2012
  2. ncbi request reprint Can hepatitis C virus infection be eradicated in people who inject drugs?
    Jason Grebely
    The Kirby Institute, UNSW Australia, Sydney, Australia Electronic address
    Antiviral Res 104:62-72. 2014
  3. pmc Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Hepatology 57:2124-34. 2013
  4. pmc Breaking down the barriers to hepatitis C virus (HCV) treatment among individuals with HCV/HIV coinfection: action required at the system, provider, and patient levels
    Jason Grebely
    The Kirby Institute, University of New South Wales, Sydney, Australia
    J Infect Dis 207:S19-25. 2013
  5. pmc Hepatitis C virus clearance, reinfection, and persistence, with insights from studies of injecting drug users: towards a vaccine
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Infect Dis 12:408-14. 2012
  6. pmc Hepatitis C virus reinfection and superinfection among treated and untreated participants with recent infection
    Jason Grebely
    Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Hepatology 55:1058-69. 2012
  7. doi request reprint Management of HCV and HIV infections among people who inject drugs
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia
    Curr Opin HIV AIDS 6:501-7. 2011
  8. pmc Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research NCHECR, University of New South Wales UNSW, Sydney, Australia
    Hepatology 52:1216-24. 2010
  9. doi request reprint Reinfection with hepatitis C virus following sustained virological response in injection drug users
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, New South Wales, Australia
    J Gastroenterol Hepatol 25:1281-4. 2010
  10. pmc Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection
    Maryam Alavi
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    J Gastroenterol Hepatol 27:957-65. 2012

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Virological responses during treatment for recent hepatitis C virus: potential benefit for ribavirin use in HCV/HIV co-infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales UNSW, Sydney, Australia
    AIDS 26:1653-61. 2012
    ..This study evaluated early virological decline during recent HCV therapy in HIV-uninfected individuals receiving pegylated interferon (PEG-IFN) monotherapy and HIV-infected individuals receiving PEG-IFN/RBV...
  2. ncbi request reprint Can hepatitis C virus infection be eradicated in people who inject drugs?
    Jason Grebely
    The Kirby Institute, UNSW Australia, Sydney, Australia Electronic address
    Antiviral Res 104:62-72. 2014
    ..This article forms part of a symposium in Antiviral Research on "Hepatitis C: next steps toward global eradication." ..
  3. pmc Plasma interferon-gamma-inducible protein-10 (IP-10) levels during acute hepatitis C virus infection
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Hepatology 57:2124-34. 2013
    ..hepatology 2013;)...
  4. pmc Breaking down the barriers to hepatitis C virus (HCV) treatment among individuals with HCV/HIV coinfection: action required at the system, provider, and patient levels
    Jason Grebely
    The Kirby Institute, University of New South Wales, Sydney, Australia
    J Infect Dis 207:S19-25. 2013
    ..This review will outline barriers to HCV care in HCV/HIV coinfection, with a particular emphasis on persons who inject drugs, proposing strategies to enhance HCV treatment uptake and outcomes...
  5. pmc Hepatitis C virus clearance, reinfection, and persistence, with insights from studies of injecting drug users: towards a vaccine
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Lancet Infect Dis 12:408-14. 2012
    ....
  6. pmc Hepatitis C virus reinfection and superinfection among treated and untreated participants with recent infection
    Jason Grebely
    Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Hepatology 55:1058-69. 2012
    ..In adjusted analysis, reinfection/superinfection occurred more often in participants with poorer social functioning at enrollment and more often in those with ongoing injecting drug use (IDU)...
  7. doi request reprint Management of HCV and HIV infections among people who inject drugs
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia
    Curr Opin HIV AIDS 6:501-7. 2011
    ..The current review focuses on the management of HCV and HIV among IDUs, focusing particularly on recent strategies to enhance assessment, uptake and response to HCV and HIV treatment...
  8. pmc Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research NCHECR, University of New South Wales UNSW, Sydney, Australia
    Hepatology 52:1216-24. 2010
    ..Early therapeutic intervention could be recommended for individuals with unfavorable IL28B genotypes...
  9. doi request reprint Reinfection with hepatitis C virus following sustained virological response in injection drug users
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, New South Wales, Australia
    J Gastroenterol Hepatol 25:1281-4. 2010
    ..However, there are little data in this regard. We evaluated HCV re-infection following sustained virologic response (SVR) among HCV-infected IDUs having received HCV treatment in a multidisciplinary program...
  10. pmc Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection
    Maryam Alavi
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    J Gastroenterol Hepatol 27:957-65. 2012
    ..Data on the effect of HCV treatment on mental health among injecting drug users (IDUs) are limited. We assessed mental health during treatment of recently acquired HCV, within a predominantly IDU population...
  11. pmc Adherence to treatment for recently acquired hepatitis C virus (HCV) infection among injecting drug users
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    J Hepatol 55:76-85. 2011
    ..We assessed 80/80 adherence (≥80% of PEG-IFN doses, ≥80% treatment), on-treatment adherence, and treatment completion in a study of treatment of recent HCV infection (ATAHC)...
  12. pmc Effective treatment of injecting drug users with recently acquired hepatitis C virus infection
    Gregory J Dore
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Gastroenterology 138:123-35.e1-2. 2010
    ..We evaluated the efficacy of treatment of recent HCV infection in IDUs with acute and early chronic HCV...
  13. pmc Factors associated with uptake of treatment for recent hepatitis C virus infection in a predominantly injecting drug user cohort: The ATAHC Study
    J Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, 376 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Drug Alcohol Depend 107:244-9. 2010
    ..Decisions about whether to initiate treatment for recently acquired HCV were mainly driven by clinical factors, rather than factors related to sociodemographics or injecting behaviors...
  14. pmc IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study
    Vijayaprakash Suppiah
    Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Sydney, Australia
    PLoS Med 8:e1001092. 2011
    ....
  15. ncbi request reprint Dynamics of HCV RNA levels during acute hepatitis C virus infection
    Behzad Hajarizadeh
    The Kirby Institute, UNSW Australia The University of New South Wales, Sydney, Australia
    J Med Virol 86:1722-9. 2014
    ..J. Med. Virol. 86: 1722-1729, 2014. © 2014 Wiley Periodicals, Inc. ..
  16. pmc The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection
    Jason Grebely
    The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
    Hepatology 59:109-20. 2014
    ..26; 95% CI: 1.52, 3.34), and HCV genotype 1 (versus non-genotype 1; AHR: 1.56; 95% CI: 1.06, 2.30). The effect of IL28B genotype and HCV genotype on spontaneous clearance was greater among females, compared to males...
  17. doi request reprint CCR5-Δ32 genotype does not improve predictive value of IL28B polymorphisms for treatment response in chronic HCV infection
    V Suppiah
    Storr Liver Unit, Westmead Millennium Institute, University of Sydney, Sydney, NSW, Australia
    Genes Immun 14:286-90. 2013
    ..Although CCR5-Δ32 may affect viral clearance within closely controlled geographical and genetic environments, we found no effect in larger cohorts treated with dual therapy. ..
  18. doi request reprint Assessment and treatment of hepatitis C virus infection among people who inject drugs in the opioid substitution setting: ETHOS study
    Maryam Alavi
    The Kirby Institute, University of New South Wales, Sydney, Australia
    Clin Infect Dis 57:S62-9. 2013
    ..HCV assessment and treatment was evaluated through an innovative model for the provision of HCV care among PWID with chronic HCV infection...
  19. doi request reprint Knowledge and barriers associated with assessment and treatment for hepatitis C virus infection among people who inject drugs
    Carla Treloar
    National Centre in HIV Social Research, The University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:918-24. 2012
    ..Further understanding is required of the relationship between HCV knowledge and treatment willingness, assessment and treatment in this population...
  20. pmc Patterns and characteristics of hepatitis C transmission clusters among HIV-positive and HIV-negative individuals in the Australian trial in acute hepatitis C
    G V Matthews
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Australia
    Clin Infect Dis 52:803-11. 2011
    ..The extent to which these separate epidemics overlap is unknown...
  21. ncbi request reprint Continued low uptake of treatment for hepatitis C virus infection in a large community-based cohort of inner city residents
    Maryam Alavi
    The Kirby Institute for Infection and Immunity in Society, The University of New South Wales, Sydney, Australia
    Liver Int 34:1198-206. 2014
    ..Despite advances in HCV treatment, recent data on treatment uptake is sparse. HCV treatment uptake and associated factors were evaluated in a community-based cohort in Vancouver, Canada...
  22. pmc Cohort Profile: The International Collaboration of Incident HIV and Hepatitis C in Injecting Cohorts (InC3) Study
    Jason Grebely
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia, Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA, CRCHUM, Universite de Montreal, Montreal, Quebec, Canada, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD, USA, Harvard Medical School, Boston, MA, USA, Tufts Medical School, Boston, MA, USA, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia, Burnet Institute, Melbourne, Victoria, Australia, Cluster Infectious Diseases, Public Health Service, Amsterdam, Netherlands and Department of Internal Medicine, Academic Medical Center, Center for Infection and Immunity, Amsterdam, Netherlands
    Int J Epidemiol 42:1649-59. 2013
    ..Potential collaborators should contact the InC(3) PI Dr Kimberley Page (kPage@psg.ucsf.edu) for further information. ..
  23. doi request reprint Case definitions for acute hepatitis C virus infection: a systematic review
    Behzad Hajarizadeh
    Viral Hepatitis Clinical Research Program, The Kirby Institute, The University of New South Wales UNSW, Sydney, NSW, Australia
    J Hepatol 57:1349-60. 2012
    ..The aim of this systematic review was to characterize case definitions for recent HCV and explore the heterogeneity in studies performed to date...
  24. doi request reprint What is killing people with hepatitis C virus infection?
    Jason Grebely
    Viral Hepatitis Clinical Research Program, The Kirby Institute for Infection and Immunity in Society, The University of New South Wales, Sydney, NSW 2010, Australia
    Semin Liver Dis 31:331-9. 2011
    ..The considerable variability in mortality rates within subpopulations of people with HCV will be outlined, such as in people who inject drugs and those with HIV co-infection...
  25. ncbi request reprint Optimizing assessment and treatment for hepatitis C virus infection in illicit drug users: a novel model incorporating multidisciplinary care and peer support
    Jason Grebely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, New South Wales, Australia
    Eur J Gastroenterol Hepatol 22:270-7. 2010
    ..We evaluated assessment and treatment for hepatitis C virus (HCV) among illicit drug users accepting referral to a weekly HCV peer-support group at a multidisciplinary community health centre...
  26. doi request reprint Epidemiology and natural history of HCV infection
    Behzad Hajarizadeh
    Viral Hepatitis Clinical Research Program, The Kirby Institute, The University of New South Wales, Sydney, NSW 2052, Australia
    Nat Rev Gastroenterol Hepatol 10:553-62. 2013
    ..Chronic hepatitis C generally progresses slowly in the initial two decades, but can be accelerated during this time as a result of advancing age and co-factors such as heavy alcohol intake and HIV co-infection. ..
  27. doi request reprint Treatment of acute HCV infection
    Jason Grebely
    Viral Hepatitis Clinical Research Program, National Center in HIV Epidemiology and Clinical Research, University of New South Wales, Corner Boundary and West Streets, Darlinghurst, Sydney, NSW 2010, Australia
    Nat Rev Gastroenterol Hepatol 8:265-74. 2011
    ..This Review highlights current knowledge of the epidemiology, diagnosis, natural history and treatment of acute HCV infection, including proposed recommendations for the assessment and treatment of this infection...
  28. pmc Declining incidence of hepatitis C virus infection among people who inject drugs in a Canadian setting, 1996-2012
    Jason Grebely
    The Kirby Institute, UNSW Australia, Sydney, New South Wales, Australia
    PLoS ONE 9:e97726. 2014
    ..People who inject drugs (PWID) are at high risk of hepatitis C virus (HCV) infection. Trends in HCV incidence and associated risk factors among PWID recruited between 1996 and 2012 in Vancouver, Canada were evaluated...
  29. doi request reprint Factors associated with hepatitis C knowledge among a sample of treatment naive people who inject drugs
    Carla Treloar
    National Centre in HIV Social Research, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 116:52-6. 2011
    ..Knowledge of hepatitis C and its treatment is one precursor to decisions about treatment...