Ian Grainge

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi Simple topology: FtsK-directed recombination at the dif site
    Ian Grainge
    School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia
    Biochem Soc Trans 41:595-600. 2013
  2. ncbi FtsK--a bacterial cell division checkpoint?
    Ian Grainge
    Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, Australia
    Mol Microbiol 78:1055-7. 2010
  3. ncbi Activation of XerCD-dif recombination by the FtsK DNA translocase
    Ian Grainge
    Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
    Nucleic Acids Res 39:5140-8. 2011
  4. ncbi Unlinking chromosome catenanes in vivo by site-specific recombination
    Ian Grainge
    Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 26:4228-38. 2007
  5. ncbi FtsK DNA translocase: the fast motor that knows where it's going
    Estelle Crozat
    Department of Biochemistry, University of Oxford, Oxford, UK
    Chembiochem 11:2232-43. 2010
  6. ncbi The Escherichia coli DNA translocase FtsK
    David J Sherratt
    Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK
    Biochem Soc Trans 38:395-8. 2010
  7. ncbi Separating speed and ability to displace roadblocks during DNA translocation by FtsK
    Estelle Crozat
    Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 29:1423-33. 2010
  8. ncbi Sporulation: SpoIIIE is the key to cell differentiation
    Ian Grainge
    Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK
    Curr Biol 18:R871-2. 2008
  9. ncbi Tracking of controlled Escherichia coli replication fork stalling and restart at repressor-bound DNA in vivo
    Christophe Possoz
    Division of Molecular Genetics, Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 25:2596-604. 2006

Detail Information

Publications9

  1. ncbi Simple topology: FtsK-directed recombination at the dif site
    Ian Grainge
    School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW 2308, Australia
    Biochem Soc Trans 41:595-600. 2013
    ..Despite years of research the mechanism for this novel form of topological filter remains unknown...
  2. ncbi FtsK--a bacterial cell division checkpoint?
    Ian Grainge
    Biological Sciences, School of Environmental and Life Sciences, University of Newcastle, Callaghan, NSW, Australia
    Mol Microbiol 78:1055-7. 2010
    ....
  3. ncbi Activation of XerCD-dif recombination by the FtsK DNA translocase
    Ian Grainge
    Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK
    Nucleic Acids Res 39:5140-8. 2011
    ....
  4. ncbi Unlinking chromosome catenanes in vivo by site-specific recombination
    Ian Grainge
    Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 26:4228-38. 2007
    ..We conclude that FtsK acts in vivo to simplify chromosomal topology as Xer recombination interconverts monomeric and dimeric chromosomes...
  5. ncbi FtsK DNA translocase: the fast motor that knows where it's going
    Estelle Crozat
    Department of Biochemistry, University of Oxford, Oxford, UK
    Chembiochem 11:2232-43. 2010
    ..Once the FtsK translocase has located the dif site it then interacts with the XerCD site-specific recombinases to activate recombination...
  6. ncbi The Escherichia coli DNA translocase FtsK
    David J Sherratt
    Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK
    Biochem Soc Trans 38:395-8. 2010
    ..In the present paper, the properties in vivo and in vitro of FtsK and its relatives are discussed in relation to the biological functions of these remarkable enzymes...
  7. ncbi Separating speed and ability to displace roadblocks during DNA translocation by FtsK
    Estelle Crozat
    Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 29:1423-33. 2010
    ..This separation of translocation velocity and ability to displace roadblocks is more consistent with a sequential escort mechanism than stochastic, hand-off, or concerted mechanisms...
  8. ncbi Sporulation: SpoIIIE is the key to cell differentiation
    Ian Grainge
    Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK
    Curr Biol 18:R871-2. 2008
    ..Several recent studies highlight the key roles of the SpoIIIE motor in this process...
  9. ncbi Tracking of controlled Escherichia coli replication fork stalling and restart at repressor-bound DNA in vivo
    Christophe Possoz
    Division of Molecular Genetics, Department of Biochemistry, University of Oxford, Oxford, UK
    EMBO J 25:2596-604. 2006
    ..Roadblocks positioned near oriC or the dif site did not prevent replication and segregation of the rest of the chromosome...