Anthony J Gill

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. ncbi Synoptic reporting improves histopathological assessment of pancreatic resection specimens
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia
    Pathology 41:161-7. 2009
  2. doi Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Sydney 2065, Australia
    Hum Pathol 41:805-14. 2010
  3. doi Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours
    Ann I McCormack
    Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia
    Clin Endocrinol (Oxf) 71:226-33. 2009
  4. ncbi Renal tumors and hereditary pheochromocytoma-paraganglioma syndrome type 4
    Anthony J Gill
    University of Sydney, Sydney, NSW, Australia
    N Engl J Med 364:885-6. 2011
  5. ncbi Understanding the genetic basis of parathyroid carcinoma
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Pacific Highway, St Leonards, Sydney, NSW, 2065, Australia
    Endocr Pathol 25:30-4. 2014
  6. pmc Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis
    Jacob Lønborg
    North Shore Heart Research Group, Kolling Institute of Medical Research, University of Sydney, Sydney, Australia
    BMC Med Imaging 13:2. 2013
  7. doi Succinate dehydrogenase (SDH) and mitochondrial driven neoplasia
    Anthony J Gill
    Department of Anatomical Pathology and Northern Cancer Translational Research Unit, Royal North Shore Hospital, St Leonards, New South Wales, Australia
    Pathology 44:285-92. 2012
  8. doi Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, New South Wales 2065, Australia
    Am J Surg Pathol 34:636-44. 2010
  9. doi Renal tumors associated with germline SDHB mutation show distinctive morphology
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, 2065, Australia
    Am J Surg Pathol 35:1578-85. 2011
  10. pmc Succinate dehydrogenase deficiency is rare in pituitary adenomas
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital University of Sydney, Sydney Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medial Research Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards HistoPath Pathology, North Ryde Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst, NSW Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Melbourne, Vic, Australia
    Am J Surg Pathol 38:560-6. 2014

Detail Information

Publications53

  1. ncbi Synoptic reporting improves histopathological assessment of pancreatic resection specimens
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Pacific Highway, St Leonards, NSW, Australia
    Pathology 41:161-7. 2009
    ..We examined whether introduction of a standardised pancreatic cancer minimum data set improved the reporting of key pathological features across multiple institutions...
  2. doi Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Sydney 2065, Australia
    Hum Pathol 41:805-14. 2010
    ..Completely absent staining is more commonly found with SDHB mutation, whereas weak diffuse staining often occurs with SDHD mutation...
  3. doi Low O6-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours
    Ann I McCormack
    Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia
    Clin Endocrinol (Oxf) 71:226-33. 2009
    ..Recent case reports detail the successful use of temozolomide in the management of aggressive pituitary tumours. O(6)-methylguanine-DNA methyltransferase (MGMT) is a DNA repair protein that counteracts the effect of temozolomide...
  4. ncbi Renal tumors and hereditary pheochromocytoma-paraganglioma syndrome type 4
    Anthony J Gill
    University of Sydney, Sydney, NSW, Australia
    N Engl J Med 364:885-6. 2011
    ..This letter indicates that immunohistochemical analysis to detect succinic dehydrogenase subunit B (SDHB) protein can screen renal tumors for underlying SDHB germline mutations at a fraction of the time and cost of formal genetic testing...
  5. ncbi Understanding the genetic basis of parathyroid carcinoma
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Pacific Highway, St Leonards, Sydney, NSW, 2065, Australia
    Endocr Pathol 25:30-4. 2014
    ....
  6. pmc Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis
    Jacob Lønborg
    North Shore Heart Research Group, Kolling Institute of Medical Research, University of Sydney, Sydney, Australia
    BMC Med Imaging 13:2. 2013
    ..Cardiac involvement in sarcoidosis is associated with a poor prognosis. In patients with right sided heart failure, differentiating between cor-pulmonale, or cardiac sarcoidosis has important implications to management...
  7. doi Succinate dehydrogenase (SDH) and mitochondrial driven neoplasia
    Anthony J Gill
    Department of Anatomical Pathology and Northern Cancer Translational Research Unit, Royal North Shore Hospital, St Leonards, New South Wales, Australia
    Pathology 44:285-92. 2012
    ..Immunohistochemistry for SDHB therefore has emerged as a useful tool to recognise these distinct neoplasias driven by mitochondrial complex 2 dysfunction and to triage formal genetic testing for the associated syndromes...
  8. doi Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, New South Wales 2065, Australia
    Am J Surg Pathol 34:636-44. 2010
    ..GISTs may therefore be divided into type 1 (SDHB positive) and type 2 (SDHB negative) subtypes...
  9. doi Renal tumors associated with germline SDHB mutation show distinctive morphology
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, 2065, Australia
    Am J Surg Pathol 35:1578-85. 2011
    ..These renal tumors appear to have a good prognosis after complete excision unless there is sarcomatoid dedifferentiation...
  10. pmc Succinate dehydrogenase deficiency is rare in pituitary adenomas
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital University of Sydney, Sydney Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medial Research Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards HistoPath Pathology, North Ryde Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst, NSW Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Melbourne, Vic, Australia
    Am J Surg Pathol 38:560-6. 2014
    ..Surveillance programs for patients with SDH mutation may be tailored to include the possibility of pituitary neoplasia; however, this is likely to be a low-yield strategy. ..
  11. doi Papillary thyroid carcinoma in pregnancy: a variant of the disease?
    James C Lee
    Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 19:4210-6. 2012
    ..We aim to examine clinically if pregnancy is an adverse factor in PTC, and if pregnancy-associated PTC are biologically different from those in nonpregnant women in terms of their miRNA profiles...
  12. doi MicroRNA profiling of sporadic and hereditary medullary thyroid cancer identifies predictors of nodal metastasis, prognosis, and potential therapeutic targets
    Deepak Abraham
    Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales, Australia
    Clin Cancer Res 17:4772-81. 2011
    ..Our aim was to study the miRNA profile of MTC to identify prognostic biomarkers and potential therapeutic targets...
  13. doi Level VII is an important component of central neck dissection for papillary thyroid cancer
    Laura Y Wang
    University of Sydney Endocrine Surgery Unit, Sydney, NSW, Australia
    Ann Surg Oncol 20:2261-5. 2013
    ..This study aimed to determine if the routine inclusion of level VII lymph node dissection as part of CND confers increased utility in the detection of macrometastatic lymph nodes compared with level VI dissection alone...
  14. doi Loss of SDHA expression identifies SDHA mutations in succinate dehydrogenase-deficient gastrointestinal stromal tumors
    Trisha Dwight
    Cancer Genetics, Hormones and Cancer Group, Kolling Institute of Medical Research, Australia
    Am J Surg Pathol 37:226-33. 2013
    ..In conclusion, 30% of SDH-deficient GISTs in this study were associated with germline SDHA mutation. Negative staining for SDHA can be used to triage formal genetic testing for SDHA when an SDH-deficient GIST is encountered...
  15. ncbi Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression
    Angela Chou
    Department of Anatomical Pathology, SydPath, St Vincent s Hospital, Sydney, NSW, Australia
    Mod Pathol 25:1307-13. 2012
    ..Therefore, IGF1R inhibition represents a potential rational therapeutic approach in this recently recognized subgroup of GIST...
  16. doi MicroRNA profiling of benign and malignant pheochromocytomas identifies novel diagnostic and therapeutic targets
    Goswin Y Meyer-Rochow
    Cancer Genetics, Hormones and Cancer Group, Kolling Institute of Medical Research, Department of Endocrine and Oncology Surgery, Royal North Shore Hospital, St Leonards, Sydney, NSW 2065, Australia
    Endocr Relat Cancer 17:835-46. 2010
    ..These data indicate that miRNAs play a pivotal role in the biology of malignant pheochromocytoma, and represent an important class of diagnostic and prognostic biomarkers and therapeutic targets warranting further investigation...
  17. doi Nuclear accumulation of e-cadherin correlates with loss of cytoplasmic membrane staining and invasion in pituitary adenomas
    Marianne S Elston
    Cancer Genetics Unit, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW, Australia
    J Clin Endocrinol Metab 94:1436-42. 2009
    ..Pituitary tumors, although typically benign, may be locally invasive, and loss of membranous E-cadherin has been reported as a marker of invasion in prolactinomas...
  18. doi BRAF(V600E) mutation is associated with an increased risk of nodal recurrence requiring reoperative surgery in patients with papillary thyroid cancer
    Christine J O'Neill
    Endocrine Surgical Unit, University of Sydney, St Leonards, New South Wales, Australia
    Surgery 148:1139-45; discussion 1145-6. 2010
    ..Some studies suggest that tumors containing BRAF(V600E) have decreased radioiodine avidity and present a greater risk of nodal recurrence and distant metastases...
  19. doi CDC73/HRPT2 CpG island hypermethylation and mutation of 5'-untranslated sequence are uncommon mechanisms of silencing parafibromin in parathyroid tumors
    Michael A Hahn
    Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, E25, St Leonards, New South Wales 2065, Australia
    Endocr Relat Cancer 17:273-82. 2010
    ....
  20. doi Familial SDHA mutation associated with pituitary adenoma and pheochromocytoma/paraganglioma
    Trisha Dwight
    Cancer Genetics, Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales 2065, Australia
    J Clin Endocrinol Metab 98:E1103-8. 2013
    ..Reports of the coexistence of pituitary adenomas and pheochromocytoma/paraganglioma are uncommon. Recently germline mutations in 2 of the genes encoding succinate dehydrogenase, SDHC and SDHD, were associated with pituitary tumors...
  21. ncbi Reflex ALK immunohistochemistry is feasible and highly specific for ALK gene rearrangements in lung cancer
    Michelle Houang
    1Cancer Diagnosis and Pathology Group, Northern Translational Cancer Research Unit, Kolling Institute of Medical Research, St Leonards 2Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards 3Sydney Medical School, University of Sydney, Sydney 4HistoPath Pathology, North Ryde 5Department of Tissue Oncology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown 6Department of Anatomical Pathology, SydPath, St Vincent s Hospital, Darlinghurst 7School of Medicine, University of Western Sydney 8Kinghorn Cancer Centre and Cancer Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Pathology 46:383-8. 2014
    ....
  22. pmc BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer
    Christopher W Toon
    1 Department of Cancer Diagnosis and Pathology, Kolling Institute of Medical Research, St Leonards, NSW, Australia 2 Histopath Pathology, North Ryde, NSW, Australia 3 Sydney Medical School, University of Sydney NSW, Australia
    Mod Pathol 27:644-50. 2014
    ..We conclude that in addition to its utility in screening for Lynch syndrome, reflex BRAFV600E and mismatch repair assessment by immunohistochemistry can be used as a powerful predictor of all-cause survival. ..
  23. ncbi Nodal metastasis microRNA expression correlates with the primary tumour in MTC
    Justin S Gundara
    Cancer Genetics Laboratory, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia Endocrine Surgical Unit, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia University of Sydney, Sydney, New South Wales, Australia Northern Translational Cancer Research Unit, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, Sydney, New South Wales, Australia
    ANZ J Surg 84:235-9. 2014
    ..Our understanding of microRNA (miRNA) profiles of metastatic disease also remains limited and may unveil novel therapeutic strategies for these patients...
  24. doi von Hippel-Lindau syndrome
    Angela Chou
    Department of Anatomical Pathology, St Vincents Hospital, Darlinghurst, NSW, Australia
    Front Horm Res 41:30-49. 2013
    ..Surveillance of carriers can reduce the burden of disease and is best performed in specialist referral centers with due consideration given to both the complex molecular pathogenesis and psychosocial aspects of the disease...
  25. pmc RON is not a prognostic marker for resectable pancreatic cancer
    Carole M Tactacan
    Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia
    BMC Cancer 12:395. 2012
    ..However, the prognostic significance of RON expression in pancreatic cancer is unknown...
  26. doi The glucocorticoid receptor is overexpressed in malignant adrenocortical tumors
    Lyndal J Tacon
    Cancer Genetics Unit, Hormones and Cancer Group, Kolling Institute of Medical Research, University of Sydney, Sydney, NSW 2006, Australia
    J Clin Endocrinol Metab 94:4591-9. 2009
    ..We recently discovered that the glucocorticoid receptor (GR) gene NR3C1 is significantly up-regulated in ACCs compared with ACAs in global gene expression studies...
  27. doi Frozen section of the pancreatic neck margin in pancreatoduodenectomy for pancreatic adenocarcinoma is of limited utility
    Tony C Y Pang
    1Sydney Medical School, University of Sydney 2Department of Upper GIT Surgery, Royal North Shore Hospital, St Leonards 3Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, St Leonards 4Anatomical Pathology, SydPath, St Vincent s Hospital, Darlinghurst 5Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, NSW, Australia
    Pathology 46:188-92. 2014
    ..Our findings question the clinical benefit of intraoperative margin assessment, particularly if re-excision cannot be performed easily and safely...
  28. doi Phosphaturic mesenchymal tumors show positive staining for somatostatin receptor 2A (SSTR2A)
    Michelle Houang
    Sydney Medical School, University of Sydney, Sydney, 2006 Australia Cancer Diagnosis and Pathology Group, Northern Translational Cancer Research Unit, Kolling Institute of Medical Research, St Leonards, 2065 Australia Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, 2065 Australia Departement de Biopathologie, Centre Leon Berard, 69373 Lyon France Electronic address
    Hum Pathol 44:2711-8. 2013
    ..Negative staining can serve as an excellent rule out test for this diagnosis. ..
  29. doi MGMT expression and pituitary tumours: relationship to tumour biology
    Ann McCormack
    Cancer Genetics Unit, Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia
    Pituitary 16:208-19. 2013
    ..These results form the basis of our proposed model to describe the role of MGMT in pituitary tumorigenesis...
  30. doi The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination
    Michael A Hahn
    Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, NSW 2065, Australia
    Hum Mol Genet 21:559-68. 2012
    ..We conclude that CDC73 is required for the maintenance of H2B-K120 monoubiquitination and propose that reduction in levels of monoubiquitinated H2B-K120 is a major mechanism whereby mutations in CDC73 exert their tumorigenic effect...
  31. doi Hypercalcaemia due to parathyroid carcinoma presenting in the third trimester of pregnancy
    Ryan G Paul
    Department of Endocrinology, Waikato Hospital, Hamilton, New Zealand
    Aust N Z J Obstet Gynaecol 52:204-7. 2012
    ..We present a case of parathyroid carcinoma in pregnancy presenting with pre-eclampsia at 32 weeks' gestation...
  32. doi Clinical and immunohistochemical features of 34 solid pseudopapillary tumors of the pancreas
    Nam Q Nguyen
    Department of Gastroenterology, Bankstown Hospital, New South Wales, Australia
    J Gastroenterol Hepatol 26:267-74. 2011
    ..Clinicopathological data regarding pancreatic solid pseudopapillary tumors (SPT) in a multiethnic country are limited. The aim of the present study was to characterize pancreatic SPT in Australia...
  33. doi Mucoepidermoid carcinoma of the thyroid: a report of three cases and postulated histogenesis
    Ruth S Prichard
    Department of Endocrine and Oncology Surgery, Royal North Shore Hospital, Sydney, Australia
    Thyroid 22:205-9. 2012
    ..We report three cases of thyroid MEC found in continuity with, and clearly arising from de-differentiation of, well-differentiated thyroid carcinomas (WDTCs)...
  34. pmc BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome
    Christopher W Toon
    Department of Anatomical Pathology Northern Cancer Translational Research Unit Familial Cancer Clinic, Royal North Shore Hospital Department of Pathology, SydPath, St Vincents Hospital, Darlinghurst Faculty of Medicine, University of NSW Sydney Medical School, University of Sydney, Sydney, NSW Department of Molecular and Cellular Pathology Department of Pathology, School of Medicine, University of Queensland Envoi Specialist Pathologists, Herston Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane, QLD Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, Vic, Australia Department of Neuropathology, Institute of Pathology, Ruprecht Karls University Clinical Cooperation Unit Neuropathology, German Cancer Research Center DKFZ, Heidelberg, Germany
    Am J Surg Pathol 37:1592-602. 2013
    ..Reflex BRAFV600E and MMR IHC are simple cheap tests that facilitate universal LS screening and identify the poor prognosis of the BRAFV600E-mutant MSS CRC phenotype. ..
  35. doi Patterns of structural recurrence in papillary thyroid cancer
    Schelto Kruijff
    University of Sydney Endocrine Surgery Unit, Royal North Shore Hospital, Suite 202, 69 Christie St, St Leonards, Sydney, NSW, 2065, Australia
    World J Surg 38:653-9. 2014
    ..This study was conducted to clarify the pattern of structural locoregional recurrence in PTC...
  36. doi Negative parafibromin staining predicts malignant behavior in atypical parathyroid adenomas
    Schelto Kruijff
    Endocrine Surgical Unit, University of Sydney, Sydney, NSW, Australia
    Ann Surg Oncol 21:426-33. 2014
    ..We investigated whether PF and PGP9.5 staining could be used to predict the behavior of atypical parathyroid adenomas--tumors with atypical features that do not fulfill WHO criteria for malignancy...
  37. pmc Immunohistochemistry for myc predicts survival in colorectal cancer
    Christopher W Toon
    Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Sydney, Australia Histopath Pathology, North Ryde, Australia
    PLoS ONE 9:e87456. 2014
    ..We conclude that myc status as determined by IHC alone can be used to predict overall survival in patients with CRC undergoing surgical resection...
  38. doi Clinicopathological and molecular aspects of foregut gastrointestinal stromal tumours
    Jason Chen
    Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia University of Sydney, Sydney, New South Wales, Australia
    ANZ J Surg 84:52-8. 2014
    ..This study describes clinicopathological and molecular characteristics in association with clinical outcome, in patients undergoing foregut GIST resection...
  39. doi Breast cancer-associated fibroblasts induce epithelial-to-mesenchymal transition in breast cancer cells
    Patsy S H Soon
    Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales, Australia
    Endocr Relat Cancer 20:1-12. 2013
    ....
  40. pmc Preoperative body composition is influenced by the stage of operable pancreatic adenocarcinoma but does not predict survival after Whipple's procedure
    Alireza Aslani
    Department of Nuclear Medicine, Northern Clinical School, University of Sydney at Royal North Shore Hospital, St Leonards, NSW, Australia
    HPB (Oxford) 12:325-33. 2010
    ..Therefore, this study was carried out to document body composition status in patients with pancreatic adenocarcinoma (PCa) presenting for a Whipple's procedure (WP) and to relate the findings to histopathology and longterm survival...
  41. ncbi Wnt pathway inhibitors are strongly down-regulated in pituitary tumors
    Marianne S Elston
    Cancer Genetics Unit, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, New South Wales 2065, Australia
    Endocrinology 149:1235-42. 2008
    ..In conclusion, our data suggest that WIF1 may be a tumor suppressor, specifically in nonfunctioning pituitary tumors, and that the Wnt pathways are important in pituitary tumorigenesis...
  42. doi Drug-induced thyroiditis and papillary carcinoma in a minocycline-pigmented black thyroid gland
    Lyndal Tacon
    Department of Endocrinology, Royal North Shore Hospital, Sydney, Australia
    Thyroid 18:795-7. 2008
    ..We postulate that in addition to causing black thyroid pigmentation, chronic minocycline use in our patient resulted in thyroiditis and subsequent hyperthyroidism. The papillary microcarcinoma was probably a coincidental finding...
  43. ncbi The incidence of mismatch repair gene defects in colorectal liver metastases
    Raul Alvarado-Bachmann
    Upper Gastrointestinal Surgical Unit, University of Sydney, Royal North Shore Hospital, Sydney, New South Wales 2065, Australia
    Mol Med Rep 10:1003-6. 2014
    ..Compared with the previously reported incidence of MSI in primary CRC, the low incidence of MSI in the current cohort of CRLM precludes its use as a marker for use in making clinical decisions regarding this condition. ..
  44. doi 19. Frozen section improves the complete excision rates for whipple's resection
    Oliver Wilson
    1Sydney Medical School, University of Sydney 2Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Sydney, NSW, Australia
    Pathology 46:S112-3. 2014
    ..116 (54%) of all cases were completely resected.There were no false positives of intraoperative frozen section and no false negatives. ..
  45. doi Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes
    Deborah J Marsh
    University of Sydney, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards, NSW 2065, Australia 61 2 9926 8486 61 2 9926 8484
    Expert Opin Med Diagn 1:377-92. 2007
    ..This review focuses on familial hyperparathyroidism and its known causative genes in the setting of neoplastic syndromes, with particular discussion of recent developments in the molecular diagnosis of parathyroid carcinoma...
  46. doi Intra-abdominal insular thyroid carcinoma metastasis
    Goswin Y Meyer-Rochow
    Department of Endocrine Surgery, Royal North Shore Hospital, University of Sydney, Australia
    Thyroid 19:527-30. 2009
    ..Here we present the management and outcome of a young patient with a large radioiodine resistant intra-peritoneal metastasis of insular thyroid cancer...
  47. doi Immunohistochemistry for Merkel cell polyomavirus is highly specific but not sensitive for the diagnosis of Merkel cell carcinoma in the Australian population
    Julie Y Paik
    The Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, 2065 Australia
    Hum Pathol 42:1385-90. 2011
    ....
  48. doi Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma
    Geoffrey Hall
    Institute of Clinical Pathology and Medical Research, Department of Anatomical Pathology, Westmead Public Hospital, Westmead, Australia
    Pathology 42:409-13. 2010
    ..We propose that staining for PMS2 and MSH6 alone will be sufficient to detect all cases of mismatch repair deficiency and should replace routine screening with all four antibodies...
  49. doi The International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society grading system has limited prognostic significance in advanced resected pulmonary adenocarcinoma
    Darin D Westaway
    Sydney Medical School, Sydney Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Royal North Shore Hospital, St Leonards HistoPath Pathology, North Ryde Departments of Anatomical Pathology, and Cardiothoracic Surgery, Royal North Shore Hospital, St Leonards, New South Wales, Australia these two authors contributed equally
    Pathology 45:553-8. 2013
    ..We assessed the prognostic value of subclassifying adenocarcinoma in this way in consecutive patients undergoing surgery...
  50. doi Improving diagnosis of tumor-induced osteomalacia with Gallium-68 DOTATATE PET/CT
    Roderick J Clifton-Bligh
    Cancer Genetics Unit, Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, New South Wales 2065, Australia
    J Clin Endocrinol Metab 98:687-94. 2013
    ..Tumors secreting fibroblast growth factor 23 are often small and difficult to find with conventional imaging...
  51. pmc Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
    Andrew V Biankin
    The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia
    Nature 491:399-405. 2012
    ....
  52. ncbi Loss of nuclear expression of parafibromin distinguishes parathyroid carcinomas and hyperparathyroidism-jaw tumor (HPT-JT) syndrome-related adenomas from sporadic parathyroid adenomas and hyperplasias
    Anthony J Gill
    Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, Australia
    Am J Surg Pathol 30:1140-9. 2006
    ..We conclude that, in the correct clinical and pathologic context, complete absence of nuclear staining for parafibromin is diagnostic of parathyroid carcinoma or an HPT-JT-related tumor...
  53. doi 19. Frozen section improves the complete excision rates for whipple's resection
    Oliver Wilson
    1Sydney Medical School, University of Sydney 2Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Sydney, NSW, Australia
    Pathology 46:S112-3. 2014
    ..116 (54%) of all cases were completely resected.There were no false positives of intraoperative frozen section and no false negatives. ..