Robert A Gibson

Summary

Affiliation: University of Adelaide
Country: Australia

Publications

  1. doi request reprint Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids
    R A Gibson
    Foodplus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, South Australia, Australia
    Prostaglandins Leukot Essent Fatty Acids 88:139-46. 2013
  2. doi request reprint Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life
    Robert A Gibson
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, South Australia, Australia
    Matern Child Nutr 7:17-26. 2011
  3. doi request reprint The effect of dairy foods on CHD: a systematic review of prospective cohort studies
    Robert A Gibson
    Child Youth and Women s Health Service, Women s and Children s Health Research Institute, Level 7, Clarence Reiger Building, North Adelaide, SA, Australia
    Br J Nutr 102:1267-75. 2009
  4. doi request reprint Fish-oil supplementation in pregnancy does not reduce the risk of gestational diabetes or preeclampsia
    Shao J Zhou
    Women s and Children s Health Research Centre, North Adelaide, Australia
    Am J Clin Nutr 95:1378-84. 2012
  5. doi request reprint Pre- and post-term growth in pre-term infants supplemented with higher-dose DHA: a randomised controlled trial
    Carmel T Collins
    Women s and Children s Health Research Institute, Child Nutrition Research Centre, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia
    Br J Nutr 105:1635-43. 2011
  6. doi request reprint Effect of increasing protein content of human milk fortifier on growth in preterm infants born at <31 wk gestation: a randomized controlled trial
    Jacqueline Miller
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, Bedford Park, Australia
    Am J Clin Nutr 95:648-55. 2012
  7. ncbi request reprint Higher dose of docosahexaenoic acid in the neonatal period improves visual acuity of preterm infants: results of a randomized controlled trial
    Lisa G Smithers
    Women s and Children s Health Research Institute and the School of Agriculture, Food and Wine, University of Adelaide, Adelaide, SA, Australia
    Am J Clin Nutr 88:1049-56. 2008
  8. doi request reprint Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 304:1675-83. 2010
  9. ncbi request reprint Nutritional adequacy of goat milk infant formulas for term infants: a double-blind randomised controlled trial
    Shao J Zhou
    Women s and Children s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia
    Br J Nutr 111:1641-51. 2014
  10. doi request reprint Dietary alpha-linolenic acid does not enhance accumulation of omega-3 long-chain polyunsaturated fatty acids in barramundi (Lates calcarifer)
    Wei Chun Tu
    Foodplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, South Australia, Australia
    Comp Biochem Physiol B Biochem Mol Biol 164:29-37. 2013

Collaborators

Detail Information

Publications45

  1. doi request reprint Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids
    R A Gibson
    Foodplus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, South Australia, Australia
    Prostaglandins Leukot Essent Fatty Acids 88:139-46. 2013
    ..We conclude it is possible to enhance the DHA status of rats fed diets containing ALA as the only source of n-3 fatty acids but only when the level of dietary PUFA is low (<3 en%)...
  2. doi request reprint Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life
    Robert A Gibson
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, South Australia, Australia
    Matern Child Nutr 7:17-26. 2011
    ....
  3. doi request reprint The effect of dairy foods on CHD: a systematic review of prospective cohort studies
    Robert A Gibson
    Child Youth and Women s Health Service, Women s and Children s Health Research Institute, Level 7, Clarence Reiger Building, North Adelaide, SA, Australia
    Br J Nutr 102:1267-75. 2009
    ..This could be due to the limited sensitivity of the dietary assessment methods to detect an effect of a single food in a mixed diet on complex clinical outcomes...
  4. doi request reprint Fish-oil supplementation in pregnancy does not reduce the risk of gestational diabetes or preeclampsia
    Shao J Zhou
    Women s and Children s Health Research Centre, North Adelaide, Australia
    Am J Clin Nutr 95:1378-84. 2012
    ..There is uncertainty regarding the efficacy of increasing n-3 long-chain PUFA (LCPUFA) intake during pregnancy in reducing the risk of gestational diabetes mellitus (GDM) and preeclampsia...
  5. doi request reprint Pre- and post-term growth in pre-term infants supplemented with higher-dose DHA: a randomised controlled trial
    Carmel T Collins
    Women s and Children s Health Research Institute, Child Nutrition Research Centre, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia
    Br J Nutr 105:1635-43. 2011
    ..Our data show that DHA up to 1 % total dietary fatty acids does not adversely affect growth...
  6. doi request reprint Effect of increasing protein content of human milk fortifier on growth in preterm infants born at <31 wk gestation: a randomized controlled trial
    Jacqueline Miller
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, Bedford Park, Australia
    Am J Clin Nutr 95:648-55. 2012
    ..Preterm human milk-fed infants often experience suboptimal growth despite the use of human milk fortifier (HMF). The extra protein supplied in fortifiers may be inadequate to meet dietary protein requirements for preterm infants...
  7. ncbi request reprint Higher dose of docosahexaenoic acid in the neonatal period improves visual acuity of preterm infants: results of a randomized controlled trial
    Lisa G Smithers
    Women s and Children s Health Research Institute and the School of Agriculture, Food and Wine, University of Adelaide, Adelaide, SA, Australia
    Am J Clin Nutr 88:1049-56. 2008
    ..Preterm infants have improved visual outcomes when fed a formula containing 0.2-0.4% docosahexaenoic acid (DHA) compared with infants fed no DHA, but the optimal DHA dose is unknown...
  8. doi request reprint Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 304:1675-83. 2010
    ..Uncertainty about the benefits of dietary docosahexaenoic acid (DHA) for pregnant women and their children exists, despite international recommendations that pregnant women increase their DHA intakes...
  9. ncbi request reprint Nutritional adequacy of goat milk infant formulas for term infants: a double-blind randomised controlled trial
    Shao J Zhou
    Women s and Children s Health Research Institute, 72 King William Road, North Adelaide, SA 5006, Australia
    Br J Nutr 111:1641-51. 2014
    ..Goat milk formula provided growth and nutritional outcomes in infants that did not differ from those provided by a standard whey-based cow milk formula. ..
  10. doi request reprint Dietary alpha-linolenic acid does not enhance accumulation of omega-3 long-chain polyunsaturated fatty acids in barramundi (Lates calcarifer)
    Wei Chun Tu
    Foodplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, South Australia, Australia
    Comp Biochem Physiol B Biochem Mol Biol 164:29-37. 2013
    ..When dietary ALA intakes were greater than 0.8% en, tissue DHA levels were inversely related to ALA intake, suggesting that high intake of dietary ALA may inhibit DHA synthesis...
  11. doi request reprint Respiratory hospitalisation of infants supplemented with docosahexaenoic acid as preterm neonates
    Kerryn Atwell
    Neonatal Medicine, Women s and Children s Hospital, North Adelaide, South Australia, Australia
    J Paediatr Child Health 49:E17-22. 2013
    ..To determine the effect of neonatal docosahexaenoic acid (DHA) supplementation in preterm infants on later respiratory-related hospitalisations...
  12. doi request reprint Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Women s and Children s Hospital, 72 King William Rd, North Adelaide SA 5006, Australia
    JAMA 301:175-82. 2009
    ..Uncertainty exists about the benefit of dietary docosahexaenoic acid (DHA) on the neurodevelopment of preterm infants...
  13. ncbi request reprint Paradoxical effect of n-3-containing vegetable oils on long-chain n-3 fatty acids in rat heart
    Leslie G Cleland
    Hanson Institute and Rheumatology Unit, Royal Adelaide Hospital, SA, Australia
    Lipids 40:995-8. 2005
    ..e., flaxseed > echium > canola > sunflower oil. This paradox may be explained by lower ALA intake leading to decreased competition for Delta6 desaturase activity between ALA and the 24:5n-3 FA precursor to DHA formation...
  14. ncbi request reprint Effect of long-chain polyunsaturated fatty acid supplementation of preterm infants on disease risk and neurodevelopment: a systematic review of randomized controlled trials
    Lisa G Smithers
    Child Health Research Institute, Child, Youth and Women s Health Service, North Adelaide, Australia
    Am J Clin Nutr 87:912-20. 2008
    ..Supplementation of preterm formulas with long-chain polyunsaturated fatty acids (LCPUFAs) is based on their effectiveness to increase blood status and improve visual outcomes. Dispute remains over their efficacy on global development...
  15. doi request reprint Improving the neurodevelopmental outcomes of low-birthweight infants
    Maria Makrides
    Women s and Children s Health Research Institute, North Adelaide, SA, Australia
    Nestle Nutr Inst Workshop Ser 74:211-21. 2013
    ..Further large-scale rigorously designed intervention trials, with long-term neurodevelopment follow-up, are required to determine the optimal nutritional supplements and the timing of their administration to LBW infants...
  16. ncbi request reprint Immunomodulatory constituents of human milk change in response to infant bronchiolitis
    Dani Louise Bryan
    Department of Pediatrics and Child Health, Flinders University, South Australia, Australia
    Pediatr Allergy Immunol 18:495-502. 2007
    ....
  17. doi request reprint Impact of fatty acid status on growth and neurobehavioural development in humans
    Maria Makrides
    Child Nutrition Research Centre, Women s and Children s Health Research Institute, Flinders Medical Centre, 72 King William Road, Bedford Park, SA 5006, Australia
    Matern Child Nutr 7:80-8. 2011
    ..Further work is required to determine whether dietary n-3 LCPUFA is neuroprotective for children from disadvantaged or low-income backgrounds...
  18. doi request reprint Maternal supplementation with docosahexaenoic acid during pregnancy does not affect early visual development in the infant: a randomized controlled trial
    Lisa G Smithers
    Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, Australia
    Am J Clin Nutr 93:1293-9. 2011
    ..The docosahexaenoic acid (DHA) intake of pregnant women is lower than estimates of the DHA accretion by the fetus, and recommendations were made to increase the DHA intake of pregnant women...
  19. doi request reprint Safety of supplementing infant formula with long-chain polyunsaturated fatty acids and Bifidobacterium lactis in term infants: a randomised controlled trial
    Robert A Gibson
    Women s and Children s Health Research Institute, Children, Youth and Women s Health Service, North Adelaide, Australia
    Br J Nutr 101:1706-13. 2009
    ..No influence of the supplements on the response to vaccines was observed. Growth characteristics of term infants fed the starter formula containing a probiotic and LC-PUFA were similar to standard formula-fed infants...
  20. ncbi request reprint The role of fats in the lifecycle stages: pregnancy and the first year of life
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
    Med J Aust 176:S111-2. 2002
    ..Debate continues about the importance of DHA supplementation for term infants; the current consensus is that the benefits of DHA supplementation in term infants are smaller than for preterm infants...
  21. ncbi request reprint Effect of iron supplementation during pregnancy on the intelligence quotient and behavior of children at 4 y of age: long-term follow-up of a randomized controlled trial
    Shao J Zhou
    Child Nutrition Research Centre and the Department of Pediatrics, Women s and Children s Hospital, University of Adelaide, North Adelaide, Australia
    Am J Clin Nutr 83:1112-7. 2006
    ..Iron supplements are often prescribed during pregnancy despite the lack of intervention trials that have assessed the effects of supplementation in pregnancy on childhood development...
  22. doi request reprint Higher protein and energy intake is associated with increased weight gain in pre-term infants
    Carmel T Collins
    Child Nutrition Research Centre, Women s and Children s Hospital, Flinders Medical Centre and Women s and Children s Health Research Institute, Adelaide, Australia
    J Paediatr Child Health 46:96-102. 2010
    ..To characterise and compare the nutritional management and growth in infants <33 weeks' gestation in two tertiary centres...
  23. ncbi request reprint Nutritional effect of including egg yolk in the weaning diet of breast-fed and formula-fed infants: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, North Adelaide, Australia
    Am J Clin Nutr 75:1084-92. 2002
    ..Egg yolks can be a source of docosahexaenoic acid (DHA) and iron but are often associated with adverse consequences on plasma cholesterol...
  24. doi request reprint Functional characterization of the chicken fatty acid elongases
    Melissa K Gregory
    Rheumatology Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    J Nutr 143:12-6. 2013
    ..In addition, the relative abundance of ELOVL2 and ELOVL5 in the liver suggests that chickens may be able to metabolize more DPA through to 24:5(n-3), the precursor of DHA, compared with other species such as rats...
  25. ncbi request reprint Nutrient intakes and status of preschool children in Adelaide, South Australia
    Shao J Zhou
    Women s and Children s Health Research Institute, Adelaide, SA
    Med J Aust 196:696-700. 2012
    ..To determine the nutrient intakes and status of preschool children from a representative population sample in Adelaide...
  26. ncbi request reprint Home environment, not duration of breast-feeding, predicts intelligence quotient of children at four years
    Shao J Zhou
    Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, South Australia, Australia
    Nutrition 23:236-41. 2007
    ..We investigated the relation between duration of breast-feeding in infancy and the intelligence quotient (IQ) of children at 4 y of age in a well-nourished population of an industrialized country...
  27. ncbi request reprint Routine iron supplementation in pregnancy has no effect on iron status of children at six months and four years of age
    Shao J Zhou
    Child Nutrition Research Centre, Flinders Medical Centre and Women s and Children s Hospital, Child Health Research Institute, North Adelaide, Australia
    J Pediatr 151:438-40. 2007
    ..The iron status at 6 months and 4 years of children born to women who were randomly allocated to receive 20 mg of iron daily in the second half of pregnancy did not differ from children of mothers in the control group...
  28. doi request reprint Early influences of nutrition on fetal growth
    Maria Makrides
    Women s and Children s Health Research Institute, Adelaide, SA, Australia
    Nestle Nutr Inst Workshop Ser 71:1-9. 2013
    ..Further nutritional intervention studies which are rigorously designed and implemented are needed particularly to delineate differential effects in developed and developing countries...
  29. doi request reprint Effect of iodine supplementation in pregnancy on child development and other clinical outcomes: a systematic review of randomized controlled trials
    Shao J Zhou
    Women s and Children s Health Research Institute, North Adelaide, Australia AJA, MM, and SJZ the School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia MM and the FOODplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, Urrbrae, Australia AJA, RAG, MM, and SJZ
    Am J Clin Nutr 98:1241-54. 2013
    ..Routine iodine supplementation during pregnancy is recommended by leading health authorities worldwide, even in countries where the iodine status of the population is sufficient...
  30. ncbi request reprint Polyunsaturated fatty acids regulate cytokine and prostaglandin E2 production by respiratory cells in response to mast cell mediators
    Dani Louise Bryan
    Department of Paediatrics and Child Health, Flinders University, Child Health Research Institute, Adelaide, South Australia, Australia
    Lipids 41:1101-7. 2006
    ....
  31. ncbi request reprint The effect of alpha-linolenic acid and linoleic acid on the growth and development of formula-fed infants: a systematic review and meta-analysis of randomized controlled trials
    Tuesday Udell
    Department of Paediatrics and Child Health, Flinders University, Bedford Park, South Australia, Australia
    Lipids 40:1-11. 2005
    ..The findings suggest that ALA-supplemented diets improve the DHA status of infants. Further studies are needed to provide convincing evidence regarding the effects of ALA supplementation of formula on infant growth and development...
  32. doi request reprint Effect of long-chain polyunsaturated fatty acid supplementation during pregnancy or lactation on infant and child body composition: a systematic review
    Beverly S Muhlhausler
    School of Agriculture, Food, and Wine, The University of Adelaide, Adelaide, Australia
    Am J Clin Nutr 92:857-63. 2010
    ....
  33. doi request reprint Barramundi (Lates calcarifer) desaturase with Δ6/Δ8 dual activities
    Wei Chun Tu
    Foodplus Research Centre, School of Agriculture, Food and Wine, Waite Campus, University of Adelaide, Adelaide, SA, Australia
    Biotechnol Lett 34:1283-96. 2012
    ....
  34. doi request reprint An alternative n-3 fatty acid elongation pathway utilising 18:3n-3 in barramundi (Lates calcarifer)
    Wei Chun Tu
    Foodplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, South Australia, Australia
    Biochem Biophys Res Commun 423:176-82. 2012
    ..The findings from this study provide molecular evidence for an alternative n-3 fatty acid elongation pathway utilising 18:3n-3 in barramundi...
  35. ncbi request reprint Cytokine production by human milk cells and peripheral blood mononuclear cells from the same mothers
    Joanna S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, South Australia, Australia
    J Clin Immunol 22:338-44. 2002
    ....
  36. ncbi request reprint Responses to immunisation with Hib conjugate vaccine in Australian breastfed and formula-fed infants
    Joanna S Hawkes
    Child Health Research Institute, Flinders Medical Centre and Flinders University, Bedford Park, South Australia, Australia
    J Paediatr Child Health 43:597-600. 2007
    ..These observations prompted us to investigate the effect of feeding method on the antibody concentration to Hib polyribosylribitol (PRP) both prior to and 3 months after the primary course of immunisation with Hib (PRP-OMP)...
  37. ncbi request reprint Essential role of fats throughout the lifecycle: summary and recommendations
    Robert A Gibson
    Child Nutrition Research Centre, Child Health Research Institute, Women s and Children s Hospital, Flinders Medical Centre, Adelaide, SA 5042, Australia
    Med J Aust 176:S107-9. 2002
  38. ncbi request reprint Efficacy and tolerability of low-dose iron supplements during pregnancy: a randomized controlled trial
    Maria Makrides
    Child Nutrition Research Centre, Child Health Research Institute, and Department of Paediatrics, University of Adelaide, Women s and Children s Hospital, North Adelaide, SA, Australia
    Am J Clin Nutr 78:145-53. 2003
    ..Iron deficiency anemia (IDA) is common in pregnant women, but previous trials aimed at preventing IDA used high-dose iron supplements that are known to cause gastrointestinal side effects...
  39. ncbi request reprint Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infants
    Maria Makrides
    Applied Nutrition Group, Child Health Research Institute, Women s and Children s Hospital, North Adelaide, SA, Australia
    Am J Clin Nutr 81:1094-101. 2005
    ..Adequate growth is an important indicator of health and well-being in infants...
  40. doi request reprint Milk fat and health consequences
    Robert A Gibson
    FOODplus Australia, University of Adelaide, Glen Osmond, SA, Australia
    Nestle Nutr Workshop Ser Pediatr Program 67:197-207. 2011
    ..g. omega-3 fatty acids, gangliosides, conjugated linoleic acid) that may counteract the effect of saturates in a well balanced diet. Surprisingly, there have been few studies that have addressed this issue...
  41. ncbi request reprint Variations in transforming growth factor beta in human milk are not related to levels in plasma
    Joanna S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, SA, 5042, Australia
    Cytokine 17:182-6. 2002
    ..6 whereas the corresponding median ratio in plasma was 7:1. There was no correlation between the concentration of either isoform of TGFbeta in milk and the corresponding TGFbeta in plasma...
  42. pmc Fatty acid desaturase 2 promoter mutation is not responsible for Δ6-desaturase deficiency
    Melissa K Gregory
    Rheumatology Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Eur J Hum Genet 19:1202-4. 2011
    ..Our results indicate that the polymorphism rs3834458 does not appear to directly affect FADS2 promoter activity and is not responsible for a previously reported Δ6-desaturase deficiency...
  43. ncbi request reprint A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha
    Joanna S Hawkes
    Child Nutrition Research Centre, Flinders Medical Centre, Bedford Park, SA, Australia
    Am J Clin Nutr 75:754-60. 2002
    ..The production of proinflammatory cytokines by human peripheral blood mononuclear cells (PBMCs) can be modified by dietary n-3 PUFAs...
  44. doi request reprint Carbohydrate intake is the main determinant of growth in infants born <33 weeks' gestation when protein intake is adequate
    Carmel T Collins
    Child Health Research Institute, Women s and Children s Hospital, North Adelaide and Flinders Medical Centre, Bedford Park, South Australia, Australia
    Nutrition 24:451-7. 2008
    ..We investigated the relative contribution of macronutrients to postnatal growth in preterm infants born <33 wk of gestation...
  45. doi request reprint Development of a fish cell culture model to investigate the impact of fish oil replacement on lipid peroxidation
    Melissa K Gregory
    School of Biological Sciences, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia
    Lipids 46:753-64. 2011
    ..The results are discussed in relation to the effects of fatty acid unsaturation on the oxidative stability of cellular lipids and the implications for sustainable aquaculture...