Manohar L Garg

Summary

Affiliation: University of Newcastle
Country: Australia

Publications

  1. ncbi request reprint Airway and circulating levels of carotenoids in asthma and healthy controls
    Lisa G Wood
    Department Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    J Am Coll Nutr 24:448-55. 2005
  2. pmc Relationship between central and peripheral fatty acids in humans
    Jade Guest
    School of Medical Sciences, University of New South Wales, Wallace Wurth Building, office 203, Sydney, NSW 2052, Australia
    Lipids Health Dis 12:79. 2013
  3. pmc Relationship between body composition, inflammation and lung function in overweight and obese asthma
    Hayley A Scott
    Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW Australia
    Respir Res 13:10. 2012
  4. ncbi request reprint Macadamia nut consumption modulates favourably risk factors for coronary artery disease in hypercholesterolemic subjects
    Manohar L Garg
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, 305C Medical Science Building, Callaghan, NSW 2308, Australia
    Lipids 42:583-7. 2007
  5. ncbi request reprint Long-chain n-3 polyunsaturated fatty acid incorporation into human atrium following fish oil supplementation
    Manohar L Garg
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW 2308, Australia
    Lipids 41:1127-32. 2006
  6. ncbi request reprint Macadamia nut consumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men
    Manohar L Garg
    Nutrition and Dietetics, School of Health Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia
    J Nutr 133:1060-3. 2003
  7. ncbi request reprint Consumption of an n-3 polyunsaturated fatty acid-enriched dip modulates plasma lipid profile in subjects with diabetes type II
    M L Garg
    Nutraceuticals Research Group, Faculty of Health, School of Biomedical Sciences, University of Newcastle, Callaghan, New South Wales, Australia
    Eur J Clin Nutr 61:1312-7. 2007
  8. doi request reprint Manipulating antioxidant intake in asthma: a randomized controlled trial
    Lisa G Wood
    Centre for Asthma and Respiratory Diseases, University of Newcastle, New South Wales, Australia
    Am J Clin Nutr 96:534-43. 2012
  9. doi request reprint Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells
    Ahmad Saedisomeolia
    Nutraceuticals Research Group, School of Biomedical Sciences, University of Newcastle, Newcastle, NSW, Australia
    Br J Nutr 101:533-40. 2009
  10. doi request reprint A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
    Lisa G Wood
    Centre for Asthma and Respiratory Disease, Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia
    J Allergy Clin Immunol 127:1133-40. 2011

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Airway and circulating levels of carotenoids in asthma and healthy controls
    Lisa G Wood
    Department Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    J Am Coll Nutr 24:448-55. 2005
    ..Elevated oxidative stress and impaired antioxidant defences are increasingly recognised features of asthma. Carotenoids are potent dietary antioxidants that may protect against asthma by reducing oxidative damage...
  2. pmc Relationship between central and peripheral fatty acids in humans
    Jade Guest
    School of Medical Sciences, University of New South Wales, Wallace Wurth Building, office 203, Sydney, NSW 2052, Australia
    Lipids Health Dis 12:79. 2013
    ..However surprisingly limited research has been conducted comparing the fatty acid composition of central and peripheral lipid stores...
  3. pmc Relationship between body composition, inflammation and lung function in overweight and obese asthma
    Hayley A Scott
    Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW Australia
    Respir Res 13:10. 2012
    ..The obese-asthma phenotype is not well defined. The aim of this study was to examine both mechanical and inflammatory influences, by comparing lung function with body composition and airway inflammation in overweight and obese asthma...
  4. ncbi request reprint Macadamia nut consumption modulates favourably risk factors for coronary artery disease in hypercholesterolemic subjects
    Manohar L Garg
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, 305C Medical Science Building, Callaghan, NSW 2308, Australia
    Lipids 42:583-7. 2007
    ..These data, combined with our previous results on cholesterol-lowering effects of macadamia nuts, suggest that regular consumption of macadamia nuts may play a role in the prevention of coronary artery disease...
  5. ncbi request reprint Long-chain n-3 polyunsaturated fatty acid incorporation into human atrium following fish oil supplementation
    Manohar L Garg
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW 2308, Australia
    Lipids 41:1127-32. 2006
    ....
  6. ncbi request reprint Macadamia nut consumption lowers plasma total and LDL cholesterol levels in hypercholesterolemic men
    Manohar L Garg
    Nutrition and Dietetics, School of Health Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia
    J Nutr 133:1060-3. 2003
    ..This study demonstrates that macadamia nut consumption as part of a healthy diet favorably modifies the plasma lipid profile in hypercholesterolemic men despite their diet being high in fat...
  7. ncbi request reprint Consumption of an n-3 polyunsaturated fatty acid-enriched dip modulates plasma lipid profile in subjects with diabetes type II
    M L Garg
    Nutraceuticals Research Group, Faculty of Health, School of Biomedical Sciences, University of Newcastle, Callaghan, New South Wales, Australia
    Eur J Clin Nutr 61:1312-7. 2007
    ..The effects of supplementing the diets of people with diabetes type II with a hummus-based dip enriched with long-chain n-3PUFA on plasma fatty acid composition and lipid levels were examined...
  8. doi request reprint Manipulating antioxidant intake in asthma: a randomized controlled trial
    Lisa G Wood
    Centre for Asthma and Respiratory Diseases, University of Newcastle, New South Wales, Australia
    Am J Clin Nutr 96:534-43. 2012
    ..Antioxidant-rich diets are associated with reduced asthma prevalence in epidemiologic studies. We previously showed that short-term manipulation of antioxidant defenses leads to changes in asthma outcomes...
  9. doi request reprint Anti-inflammatory effects of long-chain n-3 PUFA in rhinovirus-infected cultured airway epithelial cells
    Ahmad Saedisomeolia
    Nutraceuticals Research Group, School of Biomedical Sciences, University of Newcastle, Newcastle, NSW, Australia
    Br J Nutr 101:533-40. 2009
    ..EPA and AA did not change the release of inflammatory biomarkers significantly. It is concluded that DHA has a potential role in suppressing RV-induced airway inflammation...
  10. doi request reprint A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
    Lisa G Wood
    Centre for Asthma and Respiratory Disease, Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia
    J Allergy Clin Immunol 127:1133-40. 2011
    ..Dietary fat activates systemic innate immune responses, but the effect on airway responses is unknown...
  11. ncbi request reprint Improved antioxidant and fatty acid status of patients with cystic fibrosis after antioxidant supplementation is linked to improved lung function
    Lisa G Wood
    Discipline of Nutrition and Dietetics, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia
    Am J Clin Nutr 77:150-9. 2003
    ..The plasma fatty acid status of CF patients was linked to oxidative stress after respiratory exacerbations...
  12. ncbi request reprint Oxidative stress and antioxidants in athletes undertaking regular exercise training
    Trent A Watson
    Discipline of Nutrition and Dietetics, Faculty of Health, University of Newcastle, NSW 2308, Australia
    Int J Sport Nutr Exerc Metab 15:131-46. 2005
    ..These findings suggest that athletes who consume a diet rich in antioxidants have elevated plasma alpha-tocopherol and beta-carotene that were likely to be brought about by adaptive processes resulting from regular exercise...
  13. doi request reprint Dietary supplementation with n-3 PUFA does not promote weight loss when combined with a very-low-energy diet
    Irene A Munro
    Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, 305C Medical Sciences Building, The University of Newcastle, Callaghan, NSW 2308, Australia
    Br J Nutr 108:1466-74. 2012
    ..However, it would appear that supplementation with LCn-3PUFA had no significant effect on weight loss or weight maintenance over the 14 weeks...
  14. doi request reprint Lycopene-rich treatments modify noneosinophilic airway inflammation in asthma: proof of concept
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia
    Free Radic Res 42:94-102. 2008
    ..Changing dietary antioxidant intake may be contributing to rising asthma prevalence. Lycopene-rich supplements should be further investigated as a therapeutic intervention...
  15. doi request reprint Beyond blood lipids: phytosterols, statins and omega-3 polyunsaturated fatty acid therapy for hyperlipidemia
    Michelle A Micallef
    Nutraceuticals Research Group, School of Biomedical Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia
    J Nutr Biochem 20:927-39. 2009
    ..This article reviews the health benefits of phytosterols and omega-3 fatty acids, alone or in combination with statins, for the treatment/management of hyperlipidemia, with particular emphasis on the mechanisms involved...
  16. doi request reprint Dietary supplementation with long chain omega-3 polyunsaturated fatty acids and weight loss in obese adults
    Irene A Munro
    Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW 2308, Australia
    Obes Res Clin Pract 7:e173-81. 2013
    ..Nutrients that can assist in weight loss may also reduce the risk of obesity related co-morbidities...
  17. ncbi request reprint Antioxidant restriction and oxidative stress in short-duration exhaustive exercise
    Trent A Watson
    Nutrition and Dietetics, School of Health Sciences, School of Medical Practice and Population Health, University of Newcastle, NSW, 2308, Australia
    Med Sci Sports Exerc 37:63-71. 2005
    ..Oxidative stress has been shown to increase during exercise. To alleviate oxidative stress, a high intake of antioxidant rich foods or supplements may be required in trained athletes...
  18. doi request reprint Eicosapentaenoic and docosahexaenoic acid supplementations reduce platelet aggregation and hemostatic markers differentially in men and women
    Melinda Phang
    Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, NSW, Australia
    J Nutr 143:457-63. 2013
    ..With respect to thrombotic disease risk, men are more likely to benefit from supplementation with EPA, whereas women are more responsive to DHA...
  19. ncbi request reprint Induced sputum 8-isoprostane concentrations in inflammatory airway diseases
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, NSW, 2310, Australia
    Am J Respir Crit Care Med 171:426-30. 2005
    ..Analysis of 8-iso-PGF(2alpha) concentrations in induced sputum provides a useful tool for monitoring oxidative stress and investigating strategies aimed at reducing oxidative stress in airways disease...
  20. doi request reprint Dietary antioxidant restriction affects the inflammatory response in athletes
    Brendan A Plunkett
    Nutraceuticals Research Group, School of Biomedical Sciences, University of Newcastle, Callaghan, 2308 NSW, Australia
    Br J Nutr 103:1179-84. 2010
    ..In conclusion, lower dietary intakes of carotenoids alter the plasma concentrations of antioxidants and markers of inflammation at rest and in response to exercise...
  21. doi request reprint Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals
    Michelle A Micallef
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW, Australia
    Atherosclerosis 204:476-82. 2009
    ....
  22. ncbi request reprint Hypothesis: vitamin E complements polyunsaturated fatty acids in essential fatty acid deficiency in cystic fibrosis
    Lisa G Wood
    Discipline of Nutrition and Dietetics, University of Newcastle, Callaghan, New South Wales 2308, Australia
    J Am Coll Nutr 22:253-7. 2003
    ..Furthermore, antioxidant supplementation in CF may improve EFA status...
  23. ncbi request reprint Antioxidant-restricted diet reduces plasma nonesterified fatty acids in trained athletes
    Trent A Watson
    Nutrition and Dietetics, School of Health Sciences, and bHuman Physiology, School of Biomedical Science, University of Newcastle, New South Wales, 2308, Australia
    Lipids 40:433-5. 2005
    ..03) elevated. The increase in RPE may have occurred as a result of the R-AO diet and subsequent reduction in plasma NEFA; however, further research is required to confirm this conclusion...
  24. pmc Using personality as a predictor of diet induced weight loss and weight management
    Irene A Munro
    School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan NSW 2308, Australia
    Int J Behav Nutr Phys Act 8:129. 2011
    ..The aim of this study was to investigate whether personality traits could be used to match individuals to a compatible weight loss program that would maximize weight loss...
  25. ncbi request reprint The lipid-lowering effects of phytosterols and (n-3) polyunsaturated fatty acids are synergistic and complementary in hyperlipidemic men and women
    Michelle A Micallef
    Nutraceuticals Research Group, School of Biomedical Sciences, Faculty of Health, University of Newcastle, Callaghan, NSW 2308, Australia
    J Nutr 138:1086-90. 2008
    ..005), whereas phytosterol treatment alone had no effect. In conclusion, the combined supplementation with phytosterols and (n-3) LCPUFA has both synergistic and complementary lipid-lowering effects in hyperlipidemic men and women...
  26. doi request reprint Lycopene enrichment of cultured airway epithelial cells decreases the inflammation induced by rhinovirus infection and lipopolysaccharide
    Ahmad Saedisomeolia
    Nutraceuticals Research Group, School of Biomedical Sciences, University of Newcastle, NSW 2308, Australia
    J Nutr Biochem 20:577-85. 2009
    ..Lycopene also decreased the release of IL-6 and IP-10 following exposure to lipopolysaccharide. We conclude that lycopene has a potential role in suppressing rhinovirus induced airway inflammation...
  27. doi request reprint Antioxidant and anti-inflammatory effects of resveratrol in airway disease
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia
    Antioxid Redox Signal 13:1535-48. 2010
    ..Mechanisms of resveratrol action that may be relevant to respiratory disease are described. We conclude that resveratrol has potential as a therapeutic agent in respiratory disease, which should be further investigated...
  28. ncbi request reprint Vitamin E supplementation in the mitigation of carbon tetrachloride induced oxidative stress in rats
    Lesley K MacDonald-Wicks
    Nutrition and Dietetics, School of Health Science, Faculty of Health, University of Newcastle, 2308 Callaghan, NSW, Australia
    J Nutr Biochem 14:211-8. 2003
    ..The results of this study indicate that dl-alpha-tocopherol acetate supplementation was protective of lipid peroxidation when oxidative stress is induced by a pro-oxidant challenge such as CCl4...
  29. doi request reprint Prior supplementation with long chain omega-3 polyunsaturated fatty acids promotes weight loss in obese adults: a double-blinded randomised controlled trial
    Irene A Munro
    Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, 305CMedical Sciences Building, University Drive, Callaghan, NSW 2308, Australia
    Food Funct 4:650-8. 2013
    ..21% vs.-5.82%) and BMI (-7.43% vs.-5.91%) respectively (P < 0.05 for both). It would appear that supplementation with LCω-3PUFA had a time dependent effect on weight loss in females...
  30. doi request reprint Inhibition of platelet aggregation by omega-3 polyunsaturated fatty acids is gender specific-Redefining platelet response to fish oils
    Melinda Phang
    Nutraceuticals Research Group, School of Biomedical Sciences, 305C Medical Sciences Building, University of Newcastle, Callaghan, NSW 2308, Australia
    Prostaglandins Leukot Essent Fatty Acids 81:35-40. 2009
    ..EPA was equally effective in reducing platelet aggregation in both groups. These findings show that significant gender differences exist in platelet aggregation in response to various LCn-3 PUFA treatments...
  31. doi request reprint Long-chain omega-3 polyunsaturated fatty acids in the blood of children and adolescents with juvenile bipolar disorder
    Edward H Clayton
    NSW Department of Primary Industries, Wagga Wagga Agricultural Institute, Pine Gully Rd, Wagga Wagga, NSW, 2650, Australia
    Lipids 43:1031-8. 2008
    ..As RBC DHA was also negatively related to symptoms of depression, a randomised placebo-controlled study examining supplementation with LCn-3PUFA as an adjunct to standard pharmacotherapy appears warranted in this patient population...
  32. ncbi request reprint Incorporation of n-3 fatty acids into plasma and liver lipids of rats: importance of background dietary fat
    Lesley K MacDonald-Wicks
    Nutrition and Dietetics, University of Newcastle, New South Wales, Australia
    Lipids 39:545-51. 2004
    ....
  33. doi request reprint Validation of overweight children's fruit and vegetable intake using plasma carotenoids
    Tracy L Burrows
    School of Health Sciences, Faculty of Health, University of Newcastle, Newcastle, New South Wales, Australia
    Obesity (Silver Spring) 17:162-8. 2009
    ..The lower plasma carotenoid concentrations found in overweight and obese children requires further investigation...
  34. doi request reprint Oxidized vitamin E and glutathione as markers of clinical status in asthma
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, Level 3, Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1, Hunter Region Mail Centre, Newcastle, 2310 NSW, Australia
    Clin Nutr 27:579-86. 2008
    ....
  35. doi request reprint Innate immune mechanisms linking non-esterified fatty acids and respiratory disease
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, Level 3, John Hunter Hospital, Hunter Medical Research Institute, Locked Bag 1, Hunter Region Mail Centre, Newcastle, 2310 NSW, Australia
    Prog Lipid Res 48:27-43. 2009
    ..Finally, the review will discuss how the recognition of NEFA as important inflammatory stimulants in respiratory disease, leads to the possibility that pathways involved in lipid metabolism may provide therapeutic targets...
  36. ncbi request reprint Elevated plasma levels of F2 alpha isoprostane in cystic fibrosis
    C E Collins
    Department of Dietetics, John Hunter Children s Hospital, Rankin Park, New South Wales, Australia
    Lipids 34:551-6. 1999
    ..003; vitamin E, P < 0.001; and beta-carotene, P < 0.01). This study confirms significantly elevated lipid peroxidation in CF using 8-iso-PGF2 alpha levels...
  37. pmc Feasibility of omega-3 fatty acid supplementation as an adjunct therapy for people with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial
    Ashley S Fulton
    Nutritional Physiology Research Centre, Sansom Institute for Health Research, School of Health Sciences, University of South Australia, City East Campus, Frome Road, Adelaide, South Australia 5000, Australia
    Trials 14:107. 2013
    ..The aim of this article is to discuss the feasibility of conducting a trial to evaluate fish oil supplementation as adjunct therapy in people with COPD...
  38. ncbi request reprint Circulating markers to assess nutritional therapy in cystic fibrosis
    Lisa G Wood
    Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, 2310, NSW, Australia
    Clin Chim Acta 353:13-29. 2005
    ..This article provides an overview of the biomarkers useful in the prediction of the efficacy of nutritional therapy on improvements in quality and quantity of life in CF...
  39. ncbi request reprint Oxidative stress in cystic fibrosis: dietary and metabolic factors
    L G Wood
    Discipline of Nutrition and Dietetics, University of Newcastle, Callaghan, New South Wales, Australia
    J Am Coll Nutr 20:157-65. 2001
    ..The immune response appears to be a key factor causing oxidative stress. Antioxidant intervention aimed at reducing oxidative stress in CF needs to be assessed...
  40. ncbi request reprint Macronutrient intakes and development of type 2 diabetes: a systematic review and meta-analysis of cohort studies
    Amani Alhazmi
    School of Health Sciences, University of Newcastle, New South Wales, Australia
    J Am Coll Nutr 31:243-58. 2012
    ..To synthesize the best available evidence on the association between macronutrient intake and type 2 diabetes risk...
  41. doi request reprint Weight loss and metabolic profiles in obese individuals using two different approaches
    Irene A Munro
    Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, The University of Newcastle, 305C Medical Sciences Building, Callaghan, NSW 2308, Australia
    Food Funct 2:611-6. 2011
    ..05) were noted in VLED compared to those for LED diet. Short-term, rapid weight loss produced the desired ≥5% weight loss suggested to substantially reduce metabolic abnormalities associated with obesity, and to reduce health risks...
  42. pmc Reproducibility and comparative validity of a food frequency questionnaire for Australian children and adolescents
    Jane F Watson
    School of Health Sciences, Faculty of Health, University of Newcastle, Newcastle NSW, Australia
    Int J Behav Nutr Phys Act 6:62. 2009
    ..abstract:..
  43. doi request reprint Stimulation of mitochondrial reactive oxygen species production by unesterified, unsaturated fatty acids in defective human spermatozoa
    Adam J Koppers
    Discipline of Biological Sciences and ARC Centre of Excellence in Biotechnology and Development, Faculty of Science and IT, University of Newcastle, Callaghan, NSW 2308, Australia
    Free Radic Biol Med 48:112-9. 2010
    ....
  44. ncbi request reprint Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients
    Lisa G Wood
    Discipline of Nutrition and Dietetics, The University of Newcastle, Callaghan, New South Wales, Australia
    Am J Clin Nutr 75:668-75. 2002
    ..Oxidative stress and depleted antioxidant defenses occur in stable cystic fibrosis patients. During acute infection, the balance between oxidants and antioxidants may be further disturbed...
  45. ncbi request reprint Tomato extract inhibits human platelet aggregation in vitro without increasing basal cAMP levels
    Sheryl A Lazarus
    Nutrition and Dietetics, University of Newcastle, Callaghan, NSW, Australia
    Int J Food Sci Nutr 55:249-56. 2004
    ..These results provide a potential mechanism by which tomatoes contribute to cardiovascular health...
  46. doi request reprint An inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individuals
    M A Micallef
    Nutraceuticals Research Group, School of Biomedical Sciences, The University of Newcastle, Callaghan, New South Wales, Australia
    Eur J Clin Nutr 63:1154-6. 2009
    ..05). This study provides evidence that in healthy individuals, plasma n-3 fatty acid concentration is inversely related to hs-CRP concentration, a surrogate marker of CVD risk...
  47. ncbi request reprint Tomato juice and platelet aggregation in type 2 diabetes
    Sheryl A Lazarus
    JAMA 292:805-6. 2004