Richard W Francis
Affiliation: University of Western Australia
- Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3Marie S Rye
Telethon Institute for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia
BMC Med Genet 15:18. 2014..Linkage studies provide evidence for multiple putative OM susceptibility loci. This study attempts to replicate these linkages in a Western Australian (WA) population, and to identify the etiological gene(s) in a replicated region...
- FusionFinder: a software tool to identify expressed gene fusion candidates from RNA-Seq dataRichard W Francis
Division of Bioinformatics and Biostatistics, Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Australia
PLoS ONE 7:e39987. 2012..FusionFinder is made freely available for non-commercial use and can be downloaded from the project website (http://bioinformatics.childhealthresearch.org.au/software/fusionfinder/)...
- First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetesDenise Anderson
Telethon Kids Institute, The University of Western Australia, Subiaco, Western Australia, 6008, Australia
PLoS ONE 10:e0119333. 2015..49x10-4) for BMI and IGF2BP2 Pimputed_1000G = 2.55x10-6) for T2D. Our results may provide novel functional leads in understanding disease pathogenesis in this Australian Aboriginal population. ..
- Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemiaAmy L Samuels
Division of Children s Leukaemia and Cancer Research, Telethon Institute for Child Health Research, Perth, Western Australia
BMC Genomics 11:256. 2010..However, for this model to be effective for studying engraftment and therapy responses at the whole genome level, careful molecular characterisation is essential...