A Fornito

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint Schizophrenia, neuroimaging and connectomics
    Alex Fornito
    Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Neuroimage 62:2296-314. 2012
  2. pmc Competitive and cooperative dynamics of large-scale brain functional networks supporting recollection
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria 3053, Australia
    Proc Natl Acad Sci U S A 109:12788-93. 2012
  3. ncbi request reprint In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 116:467-72. 2007
  4. doi request reprint Reconciling neuroimaging and neuropathological findings in schizophrenia and bipolar disorder
    Alex Fornito
    Faculty of Medicine, Dentistry and Health Science, Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne, Parkville, Victoria, Australia
    Curr Opin Psychiatry 22:312-9. 2009
  5. doi request reprint Genetic influences on cost-efficient organization of human cortical functional networks
    Alex Fornito
    Brain Mapping Unit, Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 31:3261-70. 2011
  6. ncbi request reprint Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Hum Brain Mapp 29:478-89. 2008
  7. ncbi request reprint Variability of the paracingulate sulcus and morphometry of the medial frontal cortex: associations with cortical thickness, surface area, volume, and sulcal depth
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Hum Brain Mapp 29:222-36. 2008
  8. doi request reprint Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, School of Behavioural Science, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South, VIC 3053, Australia
    Br J Psychiatry 194:426-33. 2009
  9. pmc Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Schizophr Bull 35:973-93. 2009
  10. doi request reprint Mapping grey matter reductions in schizophrenia: an anatomical likelihood estimation analysis of voxel-based morphometry studies
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 108:104-13. 2009

Detail Information

Publications41

  1. doi request reprint Schizophrenia, neuroimaging and connectomics
    Alex Fornito
    Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, Australia
    Neuroimage 62:2296-314. 2012
    ....
  2. pmc Competitive and cooperative dynamics of large-scale brain functional networks supporting recollection
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria 3053, Australia
    Proc Natl Acad Sci U S A 109:12788-93. 2012
    ..Our findings highlight the dynamic, context-dependent nature of large-scale brain dynamics and shed light on their contribution to individual differences in behavior...
  3. ncbi request reprint In vivo evidence for early neurodevelopmental anomaly of the anterior cingulate cortex in bipolar disorder
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 116:467-72. 2007
    ..We investigated the evidence for early neurodevelopmental anomalies in the ACC and adjacent paracingulate cortex (PaC) of BD patients by studying cortical folding patterns of the region...
  4. doi request reprint Reconciling neuroimaging and neuropathological findings in schizophrenia and bipolar disorder
    Alex Fornito
    Faculty of Medicine, Dentistry and Health Science, Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne, Parkville, Victoria, Australia
    Curr Opin Psychiatry 22:312-9. 2009
    ..In this study, we overview recent sMRI findings in schizophrenia and bipolar disorder and consider how they relate to neuropathological data...
  5. doi request reprint Genetic influences on cost-efficient organization of human cortical functional networks
    Alex Fornito
    Brain Mapping Unit, Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 31:3261-70. 2011
    ....
  6. ncbi request reprint Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Hum Brain Mapp 29:478-89. 2008
    ....
  7. ncbi request reprint Variability of the paracingulate sulcus and morphometry of the medial frontal cortex: associations with cortical thickness, surface area, volume, and sulcal depth
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Hum Brain Mapp 29:222-36. 2008
    ....
  8. doi request reprint Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, School of Behavioural Science, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South, VIC 3053, Australia
    Br J Psychiatry 194:426-33. 2009
    ....
  9. pmc Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Schizophr Bull 35:973-93. 2009
    ..We discuss the potential mechanisms that might facilitate integration of these findings and consider strategies for future research...
  10. doi request reprint Mapping grey matter reductions in schizophrenia: an anatomical likelihood estimation analysis of voxel-based morphometry studies
    A Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
    Schizophr Res 108:104-13. 2009
    ....
  11. doi request reprint Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individuals
    Alex Fornito
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, Victoria, Australia
    Biol Psychiatry 64:758-65. 2008
    ..In this study, we characterized prepsychotic ACC abnormalities in a sample of individuals at ultra-high-risk (UHR) for psychosis...
  12. doi request reprint Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorder
    Alex Fornito
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 162:123-32. 2008
    ..These findings suggest that bipolar disorder is associated with more pronounced changes in the PaC, and that reliance on volumetric measures alone may obscure more subtle differences...
  13. ncbi request reprint Characterizing anterior cingulate activation in chronic schizophrenia: a group and single-subject fMRI study
    B J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
    Acta Psychiatr Scand 116:271-9. 2007
    ..In this study, we sought to further evaluate the notion of dAC hypofunction in chronic schizophrenia patients using a cognitive task specifically designed to activate this region, enabling both group and single-subject level analyses...
  14. doi request reprint A disturbed sense of self in the psychosis prodrome: linking phenomenology and neurobiology
    B Nelson
    Orygen Youth Health Research Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Neurosci Biobehav Rev 33:807-17. 2009
    ..Further empirical work examining the relationship between neurobiological and phenomenological variables may be of value in identifying risk markers for psychosis onset...
  15. ncbi request reprint A combined spectroscopic and functional MRI investigation of the dorsal anterior cingulate region in opiate addiction
    M Yucel
    ORYGEN Research Centre, Melbourne, Vic, Australia
    Mol Psychiatry 12:611, 691-702. 2007
    ....
  16. doi request reprint Major psychoses with mixed psychotic and mood symptoms: are mixed psychoses associated with different neurobiological markers?
    E Bora
    Department of Psychiatry, Melbourne Neuropsychiatry Centre, and Melbourne Health, ORYGEN Research Centre, The University of Melbourne, Melbourne, Vic, Australia
    Acta Psychiatr Scand 118:172-87. 2008
    ..As controversies mainly arise in mixed psychoses that occupy the intermediate zone between schizophrenia and BD, investigating neurobiological markers of mixed psychoses may be relevant to understanding the nature of psychotic disorders...
  17. doi request reprint Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studies
    Valentina Lorenzetti
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, Australia
    J Affect Disord 117:1-17. 2009
    ..While there is evidence to suggest that major depressive disorder (MDD) is associated with structural brain abnormalities, the precise nature of these abnormalities remains unclear...
  18. ncbi request reprint Anterior cingulate activation in antipsychotic-naïve first-episode schizophrenia
    M Yucel
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Carlton South, VIC 3053, Australia
    Acta Psychiatr Scand 115:155-8. 2007
    ..Anterior cingulate (ACC) hypo-activity is commonly observed in chronically ill schizophrenia patients. However, it is unclear whether this is secondary to persistent illness and/or medication...
  19. pmc White-matter abnormalities in adolescents with long-term inhalant and cannabis use: a diffusion magnetic resonance imaging study
    Murat Yucel
    Orygen Youth Health Research Centre, 35 Poplar Rd, Parkville, Victoria 3052, Australia
    J Psychiatry Neurosci 35:409-12. 2010
    ....
  20. doi request reprint Whole-brain anatomical networks: does the choice of nodes matter?
    Andrew Zalesky
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Neuroimage 50:970-83. 2010
    ..9 vs. sigma(4000)=53.6+/-2.2). These findings indicate that any comparison of network parameters across studies must be made with reference to the spatial scale of the nodal parcellation...
  21. doi request reprint A DTI-derived measure of cortico-cortical connectivity
    Andrew Zalesky
    Melbourne Neuropsychiatry Centre, University ofMelbourne, 3053 Carlton South, Australia
    IEEE Trans Med Imaging 28:1023-36. 2009
    ..Finally, we present connectivity maps of some notoriously difficult to track longitudinal and contralateral fasciculi...
  22. doi request reprint Network-based statistic: identifying differences in brain networks
    Andrew Zalesky
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
    Neuroimage 53:1197-207. 2010
    ....
  23. doi request reprint Anterior cingulate volume in adolescents with first-presentation borderline personality disorder
    Sarah Whittle
    ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
    Psychiatry Res 172:155-60. 2009
    ..Longitudinal studies are needed to examine the nature of this abnormality over the course of the disorder...
  24. doi request reprint Regional brain abnormalities associated with long-term heavy cannabis use
    Murat Yucel
    MAPS, ORYGEN Research Centre, 35 Poplar Rd, Melbourne, Victoria, Australia
    Arch Gen Psychiatry 65:694-701. 2008
    ..Cannabis is the most widely used illicit drug in the developed world. Despite this, there is a paucity of research examining its long-term effect on the human brain...
  25. pmc Progressive changes in the development toward schizophrenia: studies in subjects at increased symptomatic risk
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Australia
    Schizophr Bull 34:322-9. 2008
    ..Active changes during transition to illness may present the potential to intervene and ameliorate these changes with potential benefit clinically...
  26. doi request reprint Abnormal white matter microstructure in schizophrenia: a voxelwise analysis of axial and radial diffusivity
    Marc L Seal
    Melbourne Neuropsychiatry Centre, The University of Melbourne, Victoria, Australia
    Schizophr Res 101:106-10. 2008
    ..This finding suggests that the loss of white matter integrity in schizophrenia is the result of demyelination and/or changes to the axonal cytoskeleton rather than gross axonal damage...
  27. pmc Modulation of brain resting-state networks by sad mood induction
    Ben J Harrison
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
    PLoS ONE 3:e1794. 2008
    ..While these 'resting-state networks' may be relatively enduring phenomena, other evidence suggest that dynamic changes in their functional connectivity may also emerge depending on the brain state of subjects during scanning...
  28. ncbi request reprint Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder
    Murat Yucel
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria 3053, Australia
    Arch Gen Psychiatry 64:946-55. 2007
    ..However, the precise regions and the neural alterations associated with this abnormality remain unclear...
  29. ncbi request reprint State, trait and biochemical influences on human anterior cingulate function
    Murat Yucel
    Melbourne Neuropsychiatry Centre, Australia
    Neuroimage 34:1766-73. 2007
    ..They also highlight the importance of considering enduring personal characteristics when mapping human brain-behavior relationships...
  30. doi request reprint Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder
    Murat Yucel
    Melbourne Neuropsychiatry Centre, National Neuroscience Facility, Carlton South, Australia
    Aust N Z J Psychiatry 42:467-77. 2008
    ..The purpose of the present study was to investigate how ACC biochemistry in OCD varies as a function of gender, hemisphere, subregion, and symptomatology...
  31. doi request reprint The effects of gender on grey matter abnormalities in major psychoses: a comparative voxelwise meta-analysis of schizophrenia and bipolar disorder
    E Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
    Psychol Med 42:295-307. 2012
    ..This a limiting factor for comparing schizophrenia and bipolar disorder since male gender is associated with more severe neurodevelopmental abnormalities, negative symptoms and cognitive deficits in schizophrenia...
  32. ncbi request reprint Evidence for neuronal dysfunction in the anterior cingulate of patients with schizophrenia: a proton magnetic resonance spectroscopy study at 3 T
    Stephen J Wood
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Australia
    Schizophr Res 94:328-31. 2007
    ..Anterior cingulate involvement in schizophrenia is likely to be a result of neuronal loss or dysfunction...
  33. ncbi request reprint A tale of two cities: a neuroimaging investigation of Melbourne-Sydney rivalry comparing cortical thickness in healthy adults
    Dennis Velakoulis
    Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Vic, Australia
    Australas Psychiatry 15:67-71. 2007
    ..We sought to identify neurobiological correlates of Melbourne-Sydney rivalry through neuroimaging measures of a key brain region involved in cognitive and emotional regulation...
  34. doi request reprint Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder
    Emre Bora
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
    Biol Psychiatry 67:1097-105. 2010
    ..We conducted a meta-analysis of gray matter abnormalities in bipolar disorder (BD) using voxel-based morphometry studies to help clarify the structural abnormalities underpinning this condition...
  35. ncbi request reprint Morphology of the paracingulate sulcus and executive cognition in schizophrenia
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, National Neuroscience Facility, Levels 2 and 3, Alan Gilbert Building, 161 Barry St, Carlton South, Victoria 3053, Australia
    Schizophr Res 88:192-7. 2006
    ..This suggests that prior reports of impaired performance on such tasks in schizophrenia may be partly explained by the reduced frequency of a leftward PCS asymmetry in this population...
  36. ncbi request reprint The influence of sulcal variability on morphometry of the human anterior cingulate and paracingulate cortex
    Alex Fornito
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
    Neuroimage 33:843-54. 2006
    ....
  37. doi request reprint Neuroanatomical correlates of temperament in early adolescents
    Sarah Whittle
    Department of Psychiatry, University of Melbourne, Victoria 3052, Australia
    J Am Acad Child Adolesc Psychiatry 47:682-93. 2008
    ..In the present study, we examined the relation between four core temperament dimensions and anatomically defined regions of the limbic and prefrontal cortices...
  38. pmc Prefrontal and amygdala volumes are related to adolescents' affective behaviors during parent-adolescent interactions
    Sarah Whittle
    ORYGEN Research Centre, University of Melbourne, Parkville 3052, Victoria, Australia
    Proc Natl Acad Sci U S A 105:3652-7. 2008
    ..Particularly as adolescence marks a period of rapid brain maturation, our findings have implications for mental health outcomes that may be revealed later along the developmental trajectory...
  39. doi request reprint Variations in cortical folding patterns are related to individual differences in temperament
    Sarah Whittle
    ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
    Psychiatry Res 172:68-74. 2009
    ..These findings suggest that early neurodevelopmental processes contribute to individual differences in temperament. They also illustrate sexual dimorphisms in the neural underpinnings of temperament...
  40. doi request reprint Pituitary gland volume in currently depressed and remitted depressed patients
    Valentina Lorenzetti
    Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, VIC Australia
    Psychiatry Res 172:55-60. 2009
    ..In conclusion, PGV does not appear to be a marker of current or past MDD in adult patients...
  41. doi request reprint Generic aspects of complexity in brain imaging data and other biological systems
    Ed Bullmore
    Behavioural and Clinical Neurosciences Institute, University of Cambridge, Department of Psychiatry, Addenbrooke s, Hospital, Cambridge, UK
    Neuroimage 47:1125-34. 2009
    ..The aim is to provide a didactic, focussed and user-friendly introduction to the concepts of complexity science for neuroscientists and neuroimagers...