Gavin R Flematti

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint A compound from smoke that promotes seed germination
    Gavin R Flematti
    School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Science 305:977. 2004
  2. ncbi request reprint Preparation of 2H-furo[2,3-c]pyran-2-one derivatives and evaluation of their germination-promoting activity
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 55:2189-94. 2007
  3. doi request reprint Exploring the molecular mechanism of karrikins and strigolactones
    Adrian Scaffidi
    School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia
    Bioorg Med Chem Lett 22:3743-6. 2012
  4. pmc Karrikins enhance light responses during germination and seedling development in Arabidopsis thaliana
    David C Nelson
    Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Proc Natl Acad Sci U S A 107:7095-100. 2010
  5. ncbi request reprint Carlactone-independent seedling morphogenesis in Arabidopsis
    Adrian Scaffidi
    School of Chemistry and Biochemistry, The University of Western Australia, Crawley, 6009, WA, Australia
    Plant J 76:1-9. 2013
  6. doi request reprint Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis
    Mark T Waters
    ARC Centre of Excellence for Plant Energy Biology, The University of Western Australia, Crawley, WA 6009, Australia
    Development 139:1285-95. 2012
  7. pmc F-box protein MAX2 has dual roles in karrikin and strigolactone signaling in Arabidopsis thaliana
    David C Nelson
    Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Proc Natl Acad Sci U S A 108:8897-902. 2011
  8. doi request reprint Production of the seed germination stimulant karrikinolide from combustion of simple carbohydrates
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 59:1195-8. 2011
  9. doi request reprint Structure-activity relationship of karrikin germination stimulants
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 58:8612-7. 2010
  10. doi request reprint Karrikin and cyanohydrin smoke signals provide clues to new endogenous plant signaling compounds
    Gavin R Flematti
    School of Chemistry and Biochemistry, University of Western Australia, Crawley 6009, Western Australia, Australia
    Mol Plant 6:29-37. 2013

Collaborators

Detail Information

Publications25

  1. ncbi request reprint A compound from smoke that promotes seed germination
    Gavin R Flematti
    School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Science 305:977. 2004
    ..Here we show that 1 promotes germination of a number of plant species at a level similar to that observed with plant-derived smoke water...
  2. ncbi request reprint Preparation of 2H-furo[2,3-c]pyran-2-one derivatives and evaluation of their germination-promoting activity
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 55:2189-94. 2007
    ..The results show that the methyl substituent at C-3 in 1 is important for germination-promoting activity while substitution at C-7 reduces activity. In contrast, bioactivity is mostly retained with analogues substituted at C-4 or C-5...
  3. doi request reprint Exploring the molecular mechanism of karrikins and strigolactones
    Adrian Scaffidi
    School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA 6009, Australia
    Bioorg Med Chem Lett 22:3743-6. 2012
    ..Through structure-activity studies with karrikins, we now propose an alternative mechanism for karrikin and strigolactone mode of action that involves hydrolysis of the butenolide ring...
  4. pmc Karrikins enhance light responses during germination and seedling development in Arabidopsis thaliana
    David C Nelson
    Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Proc Natl Acad Sci U S A 107:7095-100. 2010
    ..These results reveal a role for karrikins in priming light responses in the emerging seedling, and suggest that the influence of karrikins on postfire ecology may not be limited to germination recruitment...
  5. ncbi request reprint Carlactone-independent seedling morphogenesis in Arabidopsis
    Adrian Scaffidi
    School of Chemistry and Biochemistry, The University of Western Australia, Crawley, 6009, WA, Australia
    Plant J 76:1-9. 2013
    ..While the commonly employed synthetic strigolactone GR24 acts non-specifically through both D14 and KAI2, carlactone is a specific effector of strigolactone signalling that acts through MAX1 and D14. ..
  6. doi request reprint Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis
    Mark T Waters
    ARC Centre of Excellence for Plant Energy Biology, The University of Western Australia, Crawley, WA 6009, Australia
    Development 139:1285-95. 2012
    ..Our results support the existence of an endogenous, butenolide-based signalling mechanism that is distinct from the strigolactone pathway, providing a molecular basis for the adaptive response of plants to smoke...
  7. pmc F-box protein MAX2 has dual roles in karrikin and strigolactone signaling in Arabidopsis thaliana
    David C Nelson
    Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Proc Natl Acad Sci U S A 108:8897-902. 2011
    ..These results suggest that a MAX2-dependent signal transduction mechanism was adapted to mediate responses to two chemical cues with distinct roles in plant ecology and development...
  8. doi request reprint Production of the seed germination stimulant karrikinolide from combustion of simple carbohydrates
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 59:1195-8. 2011
    ..The addition of l-glycine appears to be beneficial in reducing the inhibitory effect of smoke extracts and provides a greater concentration range for effective germination-promoting activity...
  9. doi request reprint Structure-activity relationship of karrikin germination stimulants
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 58:8612-7. 2010
    ..The results demonstrate that modification at the C5 position is preferred over modification at the C3, C4, or C7 positions for retaining the highest bioactivity...
  10. doi request reprint Karrikin and cyanohydrin smoke signals provide clues to new endogenous plant signaling compounds
    Gavin R Flematti
    School of Chemistry and Biochemistry, University of Western Australia, Crawley 6009, Western Australia, Australia
    Mol Plant 6:29-37. 2013
    ..Cyanohydrins occur widely in plants and have a role in defense against other organisms, but an additional role in endogenous cyanide signaling should also now be considered...
  11. doi request reprint Solar irradiation of the seed germination stimulant karrikinolide produces two novel head-to-head cage dimers
    Adrian Scaffidi
    School of Chemistry and Biochemistry, The University of Western Australia, 35 Stirling Highway, Crawley, 6009 WA, Australia
    Org Biomol Chem 10:4069-73. 2012
    ..We now report that solar irradiation of karrikinolide yields two novel head-to-head cage photodimers with the formation, stability and bioactivity of both presented herein...
  12. doi request reprint Burning vegetation produces cyanohydrins that liberate cyanide and stimulate seed germination
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, Western Australia 6009, Australia
    Nat Commun 2:360. 2011
    ..We propose that glyceronitrile serves as an ecological store for cyanide and is an important cue for stimulating seed germination and landscape regeneration after fires...
  13. ncbi request reprint The origins and mechanisms of karrikin signalling
    Mark T Waters
    Australian Research Council Centre of Excellence in Plant Energy Biology, University of Western Australia, Crawley, WA 6009, Australia
    Curr Opin Plant Biol 16:667-73. 2013
    ..The usual function of KAI2 is unclear, but we hypothesise that the similarity between karrikins and the endogenous ligand for KAI2 made adaptation of some plants to karrikins possible. ..
  14. pmc Karrikins force a rethink of strigolactone mode of action
    Mark T Waters
    Centre of Excellence in Plant Energy Biology, The University of Western Australia, Crawley, WA Australia
    Plant Signal Behav 7:969-72. 2012
    ..The inference is that nucleophilic attack on SL and KAR by α/β-hydrolases is required for their bioactivity, but the hydrolysis products are not...
  15. pmc The structure of the karrikin-insensitive protein (KAI2) in Arabidopsis thaliana
    Rohan Bythell-Douglas
    School of Chemistry and Biochemistry, The University of Western Australia, Crawley, WA, Australia
    PLoS ONE 8:e54758. 2013
    ..The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling...
  16. pmc Prior hydration of Brassica tournefortii seeds reduces the stimulatory effect of karrikinolide on germination and increases seed sensitivity to abscisic acid
    Rowena L Long
    Western Australian Herbicide Resistance Initiative, School of Plant Biology, The University of Western Australia, 35 Stirling Highway, Crawley 6009, Western Australia, Australia
    Ann Bot 105:1063-70. 2010
    ....
  17. doi request reprint Mycotoxins produced by Fusarium spp. associated with Fusarium head blight of wheat in Western Australia
    Diana C Tan
    School of Plant Biology, Faculty of Natural and Agricultural Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    Mycotoxin Res 28:89-96. 2012
    ..This study highlights the need for monitoring not just for the presence of the specific Fusarium spp. present in any affected grain but also for their potential mycotoxin and other toxic secondary metabolites...
  18. doi request reprint Identification of alkyl substituted 2H-furo[2,3-c]pyran-2-ones as germination stimulants present in smoke
    Gavin R Flematti
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    J Agric Food Chem 57:9475-80. 2009
    ..The analogue, 3,5-dimethyl-2H-furo[2,3-c]pyran-2-one (3), was identified at levels that indicate that it is a contributor to the overall germination-promoting activity of crude smoke extracts...
  19. doi request reprint Toxigenicity of enniatins from Western Australian Fusarium species to brine shrimp (Artemia franciscana)
    Diana C Tan
    School of Plant Biology, Faculty of Natural and Agricultural Sciences, The University of Western Australia, Crawley, Western Australia 6009, Australia
    Toxicon 57:817-25. 2011
    ....
  20. pmc Karrikins discovered in smoke trigger Arabidopsis seed germination by a mechanism requiring gibberellic acid synthesis and light
    David C Nelson
    Plant Energy Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    Plant Physiol 149:863-73. 2009
    ..The observed requirements for light and GA biosynthesis provide the first insights into the karrikin mode of action...
  21. doi request reprint Mycotoxins produced by Fusarium species associated with annual legume pastures and 'sheep feed refusal disorders' in Western Australia
    Diana C Tan
    School of Plant Biology, Faculty of Natural and Agricultural Sciences, The University of Western Australia, Crawley, WA, 6009, Australia
    Mycotoxin Res 27:123-35. 2011
    ..of the incidence of F. brachygibbosum and F. venenatum in Australia and of F. tricinctum in Western Australia; and of mycotoxin production by Fusarium species from Western Australia...
  22. doi request reprint Ethynylbenzenoid metabolites of Antrodia camphorata: synthesis and inhibition of TNF expression
    Marco Buccini
    School of Chemistry and Biochemistry, The University of Western Australia, Perth, WA, Australia
    Org Biomol Chem 12:1100-13. 2014
    ..Antrocamphin A (2) inhibits Tumour Necrosis Factor (TNF) reporter gene expression, but its development as an anti-inflammatory agent may be limited by cytotoxicity...
  23. doi request reprint Mechanism of the dehydrogenase reaction of DmpFG and analysis of inter-subunit channeling efficiency and thermodynamic parameters in the overall reaction
    Natalie E Smith
    School of Chemistry and Biochemistry, University of Western Australia, Crawley, WA 6009, Australia
    Int J Biochem Cell Biol 45:1878-85. 2013
    ..This supports the concept of allosteric structural communication between the two enzymes to coordinate their activities...
  24. doi request reprint Stable triazolylphosphonate analogues of phosphohistidine
    Shin Mukai
    School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA 6009, Australia
    Amino Acids 43:857-74. 2012
    ..Herein, the design and concise synthesis of stable triazolylphosphonate analogues of N1- and N3-phosphohistidine, and derivatives suitable for bioconjugation, are described...
  25. pmc Symbiodinium genotypic and environmental controls on lipids in reef building corals
    Timothy F Cooper
    Australian Institute of Marine Science, UWA Oceans Institute, Crawley, Western Australia, Australia
    PLoS ONE 6:e20434. 2011
    ....