B Fazekas de St Groth

Summary

Affiliation: University of Sydney
Country: Australia

Publications

  1. pmc Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    Nabila Seddiki
    Centenary Institute of Cancer Medicine and Cell Biology, Faculty of Medicine, University of Sydney, Newtown, NSW 2042, Australia
    J Exp Med 203:1693-700. 2006
  2. ncbi request reprint The role of T cells in the regulation of B cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Int Rev Immunol 15:73-99. 1997
  3. ncbi request reprint Experimental models linking dendritic cell lineage, phenotype and function
    Barbara Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Immunol Cell Biol 80:469-76. 2002
  4. ncbi request reprint DCs and peripheral T cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag No 6, Newtown, NSW, 2042, Australia
    Semin Immunol 13:311-22. 2001
  5. ncbi request reprint T cell activation: in vivo veritas
    Barbara Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW 2042, Australia
    Immunol Cell Biol 82:260-8. 2004
  6. ncbi request reprint Carboxyfluorescein diacetate succinimidyl ester and the virgin lymphocyte: a marriage made in heaven
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia
    Immunol Cell Biol 77:530-8. 1999
  7. ncbi request reprint The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Immunol Today 19:448-54. 1998
  8. ncbi request reprint Nature versus nurture: contributions of developmental programming and the microenvironment to B cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia
    Immunol Cell Biol 76:369-72. 1998
  9. ncbi request reprint Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model
    B N Lambrecht
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Sydney, Australia
    J Immunol 164:2937-46. 2000
  10. pmc The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model
    L Girgis
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Sydney, New South Wales 2042, Australia
    J Exp Med 189:265-78. 1999

Collaborators

Detail Information

Publications24

  1. pmc Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    Nabila Seddiki
    Centenary Institute of Cancer Medicine and Cell Biology, Faculty of Medicine, University of Sydney, Newtown, NSW 2042, Australia
    J Exp Med 203:1693-700. 2006
    ....
  2. ncbi request reprint The role of T cells in the regulation of B cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Int Rev Immunol 15:73-99. 1997
    ....
  3. ncbi request reprint Experimental models linking dendritic cell lineage, phenotype and function
    Barbara Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Immunol Cell Biol 80:469-76. 2002
    ....
  4. ncbi request reprint DCs and peripheral T cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Locked Bag No 6, Newtown, NSW, 2042, Australia
    Semin Immunol 13:311-22. 2001
    ..The types and functional status of the DCs that present antigen in each case remain controversial. This review will summarize the indirect evidence that underlies some of the hypotheses that account for peripheral T cell tolerance...
  5. ncbi request reprint T cell activation: in vivo veritas
    Barbara Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW 2042, Australia
    Immunol Cell Biol 82:260-8. 2004
    ....
  6. ncbi request reprint Carboxyfluorescein diacetate succinimidyl ester and the virgin lymphocyte: a marriage made in heaven
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia
    Immunol Cell Biol 77:530-8. 1999
    ..Our data have allowed us to classify and understand immune responses in novel ways, suggesting many further avenues of enquiry and indicating previously unrecognized relationships between cell division and eventual cell fate...
  7. ncbi request reprint The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Immunol Today 19:448-54. 1998
    ..Here, Barbara Fazekas de St Groth discusses evolutionary aspects of the functional distinction between these two types of dendritic cells...
  8. ncbi request reprint Nature versus nurture: contributions of developmental programming and the microenvironment to B cell tolerance
    B Fazekas de St Groth
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, New South Wales, Australia
    Immunol Cell Biol 76:369-72. 1998
    ..If this postulate is accepted, induction of B cell self-tolerance in both the bone marrow and periphery follows the simple and elegant rules originally laid down by Bretscher and Cohn...
  9. ncbi request reprint Induction of rapid T cell activation, division, and recirculation by intratracheal injection of dendritic cells in a TCR transgenic model
    B N Lambrecht
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Sydney, Australia
    J Immunol 164:2937-46. 2000
    ..The response is initially localized in the mediastinal lymph nodes, but subsequently spreads systemically. This system should allow us to study the early events leading to sensitization to inhaled Ag...
  10. pmc The avidity spectrum of T cell receptor interactions accounts for T cell anergy in a double transgenic model
    L Girgis
    Centenary Institute of Cancer Medicine and Cell Biology, Newtown, Sydney, New South Wales 2042, Australia
    J Exp Med 189:265-78. 1999
    ....
  11. ncbi request reprint Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo
    Elena Shklovskaya
    Centenary Institute of Cancer Medicine and Cell Biology, Faculty of Medicine, University of Sydney, New South Wales, Australia
    J Immunol 181:418-30. 2008
    ..Thus, m-dDCs and m-LCs display distinct behavior in cutaneous lymph nodes while sharing the ability to interact specifically with T cells to control the immune response...
  12. ncbi request reprint Severely impaired clonal deletion of CD4+ T cells in low-dose irradiated mice: role of T cell antigen receptor and IL-7 receptor signals
    Elena Shklovskaya
    Centenary Institute of Cancer Medicine and Cell Biology, Faculty of Medicine, University of Sydney, Newtown, New South Wales 2042, Australia
    J Immunol 177:8320-30. 2006
    ..Failure of clonal deletion in irradiated hosts represents a novel mechanism limiting TCR diversity in a lymphopenic environment and may contribute to subsequent autoimmunity...
  13. pmc Experimental models to investigate the function of dendritic cell subsets: challenges and implications
    D G Hancock
    Centenary Institute of Cancer Medicine and Cell Biology and the Discipline of Dermatology, University of Sydney, Sydney, NSW, Australia
    Clin Exp Immunol 171:147-54. 2013
    ..In this paper we review the limitations associated with many of the current DC models and highlight some of the underlying difficulties involved in studying the function of murine DC subsets...
  14. ncbi request reprint Improved protection against disseminated tuberculosis by Mycobacterium bovis bacillus Calmette-Guerin secreting murine GM-CSF is associated with expansion and activation of APCs
    Anthony A Ryan
    Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, Camperdown, Australia
    J Immunol 179:8418-24. 2007
    ..tuberculosis infection in humans...
  15. ncbi request reprint Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue
    H Korner
    Centenary Institute of Cancer Medicine and Cell Biology, Sydney, Australia
    Eur J Immunol 27:2600-9. 1997
    ....
  16. doi request reprint Visualizing dendritic cell migration within the skin
    Ben Roediger
    The Centenary Institute for Cancer Medicine and Cell Biology, Newtown, NSW, Australia
    Histochem Cell Biol 130:1131-46. 2008
    ..In particular, we detail our current use of multi-photon excitation (MPE) microscopy of murine skin to dissect the migratory behavior of DCs in vivo...
  17. ncbi request reprint Prediction of high affinity class I-restricted multiple myeloma idiotype peptide epitopes
    Daniel M Y Szea
    Institute of Haematology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia
    Leuk Lymphoma 44:1557-68. 2003
    ....
  18. pmc Effects of DNA- and Mycobacterium bovis BCG-based delivery of the Flt3 ligand on protective immunity to Mycobacterium tuberculosis
    James A Triccas
    Microbial Pathogenesis and Immunity Group, Discipline of Infectious Diseases and Immunology, University of Sydney, Sydney, Australia
    Infect Immun 75:5368-75. 2007
    ..These results demonstrate the potential of in vivo targeting of DCs to improve antimycobacterial vaccine efficacy...
  19. ncbi request reprint Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8 T-cell activation by bone marrow-derived cells
    David G Bowen
    A W Morrow Gastroenterology and Liver Centre and Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia
    Gastroenterology 123:1252-64. 2002
    ..Mouse transgenic models were therefore developed to investigate whether bystander damage to non-antigen-bearing hepatocytes occurs in vivo...
  20. ncbi request reprint Clonal cytotoxic T cells in myeloma
    Daniel M Y Sze
    Institute of Haematology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Leuk Lymphoma 44:1667-74. 2003
    ..Finally, the specificities of these clinically important CD8+ T cell populations will be discussed in the context of immunotherapy...
  21. doi request reprint Accelerated age-dependent transition of human regulatory T cells to effector memory phenotype
    Brigitte Santner-Nanan
    Discipline of Paediatrics, Nepean Clinical School, University of Sydney, Penrith 2751, New South Wales, Australia
    Int Immunol 20:375-83. 2008
    ..However, number and function are remarkably stable throughout life...
  22. ncbi request reprint Clonal cytotoxic T cells are expanded in myeloma and reside in the CD8(+)CD57(+)CD28(-) compartment
    D M Sze
    Institute of Haematology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
    Blood 98:2817-27. 2001
    ....
  23. ncbi request reprint Balancing tolerance and immunity: the role of dendritic cell and T cell subsets
    Elena Shklovskaya
    Centenary Institute of Cancer Medicine and Cell Biology, University of Sydney, Australia
    Methods Mol Biol 380:25-46. 2007
    ..In this review, we summarize the current state of knowledge in the field, highlighting the areas where further investigation is likely to advance our understanding of this fundamental immunological interaction...
  24. pmc Special regulatory T-cell review: T-cell dependent suppression revisited
    Antony Basten
    Garvan Institute of Medical Research, Sydney, NSW, Australia
    Immunology 123:33-9. 2008
    ..Adapted from The Charge of the Light Brigade, Alfred, Lord Tennyson)..