Affiliation: University of New South Wales
Fath T, Fischer R, Dehmelt L, Halpain S, Fowler V. Tropomodulins are negative regulators of neurite outgrowth. Eur J Cell Biol. 2011;90:291-300 pubmed publisher
Nguyen H, Ruhoff A, Fath T, Jones N. Hypoxic postconditioning enhances functional recovery following endothelin-1 induced middle cerebral artery occlusion in conscious rats. Exp Neurol. 2018;: pubmed publisher
..Our data suggest that HPC-induced neuroprotection was mediated by enhanced astrocyte function, which may have contributed to functional recovery after stroke. ..
Brettle M, Suchowerska A, Chua S, Ittner L, Fath T. Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons. Neurosci Lett. 2015;609:223-8 pubmed publisher
Brettle M, Patel S, Fath T. Tropomyosins in the healthy and diseased nervous system. Brain Res Bull. 2016;126:311-323 pubmed publisher
Fath T, Agnes Chan Y, Vrhovski B, Clarke H, Curthoys N, Hook J, et al
. New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. Eur J Cell Biol. 2010;89:489-98 pubmed publisher
..Although functional redundancy does not exist between tropomyosin genes, these results suggest that significant redundancy exists between products from the same gene. ..
Fröhlich D, Suchowerska A, Spencer Z, von Jonquieres G, Klugmann C, Bongers A, et al
. In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiol Dis. 2017;97:24-35 pubmed publisher
..In summary, our data is an important contribution to a better understanding of DARS function and HBSL pathology. ..
Gray K, Kostyukova A, Fath T. Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function. Mol Cell Neurosci. 2017;84:48-57 pubmed publisher
..To facilitate future research regarding their joint role in actin regulation in the nervous system, we will comprehensively discuss Tpm and Tmod and their known functions within molecular systems that influence neuronal development. ..