Research Topics
| M E FabianiSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
In vivo inhibition of angiotensin receptors in the rat kidney by candesartan cilexetil: a comparison with losartanM E Fabiani
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, Vic, Australia
Am J Hypertens 13:1005-13. 2000..Tissue blockade of Ang II receptors in target organs, such as the kidney, may contribute to the beneficial effects of Ang II receptor antagonists as antihypertensive agents...
Comparative in vivo effects of irbesartan and losartan on angiotensin II receptor binding in the rat kidney following oral administrationM E Fabiani
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, Victoria 3084, Australia
Clin Sci (Lond) 99:331-41. 2000..Inhibition of angiotensin II receptors in target tissues such as the kidney may represent an important action of AT(1) receptor antagonists, which may contribute to the beneficial effects of these agents in the clinical setting...
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasiaM E Fabiani
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg VIC 3084, Australia
J Endocrinol 171:97-108. 2001..These data provide direct evidence in support of a functional role for the local RAS in modulating sympathetic transmission in the prostate, which may have important implications for the pathophysiology of BPH...
Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2)27 rat: effect of angiotensin-converting enzyme inhibitionMaurice E Fabiani
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, VIC 3084, Australia
Int J Biochem Cell Biol 35:973-83. 2003..Moreover, AT(1) receptor protein and mRNA expression in the prostate may be inversely modulated...
Angiotensin AT(4) receptors in the normal human prostate and benign prostatic hyperplasiaD T Dinh
Department of Medicine and Clinical Pharmacology and Therapeutics Unit, Austin and Repatriation Medical Centre, University of Melbourne, Heidelberg VIC. 3084, Australia
Mol Cell Endocrinol 184:187-92. 2001..The observation that AT(4) receptors appear reduced in BPH suggests that the AT(4) receptor may undergo agonist-induced receptor internalisation, possibly due to increased local tissue levels of Ang IV in BPH...
Localization of angiotensin-converting enzyme in the human prostate: pathological expression in benign prostatic hyperplasiaL Nassis
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, VIC 3084, Australia
J Pathol 195:571-9. 2001..These data support the concept that hyperactivity of the local RAS in the prostate may be involved in the pathogenesis of BPH...
Angiotensin receptors: distribution, signalling and functionD T Dinh
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Austin Campus, Studley Road, Heidelberg, VIC 3084, Australia
Clin Sci (Lond) 100:481-92. 2001..In this review, we discuss recent advances in our understanding of Ang II receptors, in particular, their distribution, signalling and function...
Evidence for activation of the renin-angiotensin system in the human prostate: increased angiotensin II and reduced AT(1) receptor expression in benign prostatic hyperplasiaDiem T Dinh
Department of Medicine, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, VIC 3084, Australia
J Pathol 196:213-9. 2002..These data extend previous findings in support of the novel concept that overactivity of the renin-angiotensin system (RAS) may be involved in the pathophysiology of BPH...
Cromakalim inhibits transmitter acetylcholine release in rat trachea by an action on epithelial cells and a diffusible factorRoss Vlahos
CRC for Chronic Inflammatory Diseases, Departments of Medicine and Pharmacology, The University of Melbourne, 3010, Parkville, Vic, Australia
Naunyn Schmiedebergs Arch Pharmacol 368:256-61. 2003....
