Peter R Ebeling

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint Osteoporosis in men
    Peter R Ebeling
    Department of Endocrinology, Australian Institute of Musculoskeletal Science, North West Academic Centre, University of Melbourne, Western Health, Victoria, Australia
    Curr Opin Rheumatol 25:542-52. 2013
  2. pmc Efficacy and safety of vertebroplasty for treatment of painful osteoporotic vertebral fractures: a randomised controlled trial [ACTRN012605000079640]
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, 183 Wattletree Rd, Malvern Victoria, Australia
    BMC Musculoskelet Disord 9:156. 2008
  3. pmc What is the clinical and ethical importance of incidental abnormalities found by knee MRI?
    Rebecca Grainger
    Department of Medicine, Wellington School of Medicine, University of Otago, 23A Mein St, Newtown, Wellington South 6021, New Zealand
    Arthritis Res Ther 10:R18. 2008
  4. ncbi request reprint Routine screening for vitamin D deficiency in early pregnancy: past its due date?
    Peter R Ebeling
    Med J Aust 194:332-3. 2011
  5. doi request reprint Approach to the patient with transplantation-related bone loss
    Peter R Ebeling
    Department of Medicine Royal Melbourne Hospital Western Hospital and Endocrinology, The University of Melbourne, Western Hospital, Gordon Street, Footscray 3011, Victoria, Australia
    J Clin Endocrinol Metab 94:1483-90. 2009
  6. ncbi request reprint Transplantation osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    Curr Osteoporos Rep 5:29-37. 2007
  7. ncbi request reprint Idiopathic or hypogonadal osteoporosis in men: current and future treatment options
    Peter R Ebeling
    Department of Diabetes and Endocrinology, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Victoria 3050, Australia
    Treat Endocrinol 3:381-91. 2004
  8. doi request reprint Androgens and osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, The University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    Curr Opin Endocrinol Diabetes Obes 17:284-92. 2010
  9. doi request reprint Clinical practice. Osteoporosis in men
    Peter R Ebeling
    Department of Medicine, Royal Melbourne Hospital Western Hospital, and University of Melbourne, Western Hospital, Melbourne, Victoria, Australia
    N Engl J Med 358:1474-82. 2008
  10. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013

Detail Information

Publications48

  1. doi request reprint Osteoporosis in men
    Peter R Ebeling
    Department of Endocrinology, Australian Institute of Musculoskeletal Science, North West Academic Centre, University of Melbourne, Western Health, Victoria, Australia
    Curr Opin Rheumatol 25:542-52. 2013
    ..Timely diagnosis and treatment of osteoporosis in men are therefore critical. Secondary causes for osteoporosis are common and need to be excluded. Absolute fracture risk assessment guides selection of men for anti-osteoporotic therapy...
  2. pmc Efficacy and safety of vertebroplasty for treatment of painful osteoporotic vertebral fractures: a randomised controlled trial [ACTRN012605000079640]
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, 183 Wattletree Rd, Malvern Victoria, Australia
    BMC Musculoskelet Disord 9:156. 2008
    ....
  3. pmc What is the clinical and ethical importance of incidental abnormalities found by knee MRI?
    Rebecca Grainger
    Department of Medicine, Wellington School of Medicine, University of Otago, 23A Mein St, Newtown, Wellington South 6021, New Zealand
    Arthritis Res Ther 10:R18. 2008
    ..The prevalence of incidental, potentially clinically significant abnormalities identified by MRI and their clinical significance in a population undergoing knee MRI in research studies are unknown...
  4. ncbi request reprint Routine screening for vitamin D deficiency in early pregnancy: past its due date?
    Peter R Ebeling
    Med J Aust 194:332-3. 2011
  5. doi request reprint Approach to the patient with transplantation-related bone loss
    Peter R Ebeling
    Department of Medicine Royal Melbourne Hospital Western Hospital and Endocrinology, The University of Melbourne, Western Hospital, Gordon Street, Footscray 3011, Victoria, Australia
    J Clin Endocrinol Metab 94:1483-90. 2009
    ..Active vitamin D metabolites may have additional benefits in reducing hyperparathyroidism, particularly after kidney transplantation...
  6. ncbi request reprint Transplantation osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    Curr Osteoporos Rep 5:29-37. 2007
    ..Large, multicenter treatment trials with oral or parenteral bisphosphonates and calcitriol are recommended...
  7. ncbi request reprint Idiopathic or hypogonadal osteoporosis in men: current and future treatment options
    Peter R Ebeling
    Department of Diabetes and Endocrinology, The University of Melbourne, The Royal Melbourne Hospital, Parkville, Victoria 3050, Australia
    Treat Endocrinol 3:381-91. 2004
    ..In the future, selective androgen receptor modulating drugs may be useful in the prevention and treatment of osteoporosis, and in increasing lean body mass in men, without having adverse effects on prostate and breast tissue...
  8. doi request reprint Androgens and osteoporosis
    Peter R Ebeling
    Department of Medicine RMH WH, The University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    Curr Opin Endocrinol Diabetes Obes 17:284-92. 2010
    ..Osteoporosis in men is an important public health problem. An improved understanding of the role of androgens in the pathophysiology of bone loss will lead to new treatments...
  9. doi request reprint Clinical practice. Osteoporosis in men
    Peter R Ebeling
    Department of Medicine, Royal Melbourne Hospital Western Hospital, and University of Melbourne, Western Hospital, Melbourne, Victoria, Australia
    N Engl J Med 358:1474-82. 2008
  10. doi request reprint Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, Melbourne, Australia
    Am J Kidney Dis 62:58-66. 2013
    ..Low serum 25-hydroxyvitamin D (25[OH]D) levels have been associated with chronic kidney disease in cross-sectional studies. However, this association has not been studied prospectively in a large general population-based cohort...
  11. pmc 25-Hydroxyvitamin D levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study
    Matthew J Damasiewicz
    Department of Nephrology, Monash Medical Centre, 246 Clayton Road, Clayton, 3168, Victoria, Australia
    BMC Nephrol 13:55. 2012
    ..We explored the relationship between 25(OH)D levels and prevalent chronic kidney disease (CKD), albuminuria and impaired GFR, in a national, population-based cohort of Australian adults (AusDiab Study)...
  12. doi request reprint Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population-based study
    Robin M Daly
    Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    Clin Endocrinol (Oxf) 77:26-35. 2012
    ..This study evaluated the vitamin D status of Australian adults aged ≥25 years and risk factors associated with vitamin D deficiency in this population. Design and..
  13. doi request reprint Frequent walking, but not total physical activity, is associated with increased fracture incidence: a 5-year follow-up of an Australian population-based prospective study (AusDiab)
    Riku Nikander
    Department of Medicine, NorthWest Academic Centre, University of Melbourne, Western Hospital, Melbourne, Australia
    J Bone Miner Res 26:1638-47. 2011
    ..In conclusion, older adults who adhered to the current PA guidelines were not protected against fragility fractures, but more frequent walking was associated with an increased fracture risk...
  14. ncbi request reprint The relative effect of endogenous estradiol and androgens on menopausal bone loss: a longitudinal study
    Janet R Guthrie
    Office for Gender and Health, Department of Psychiatry, University of Melbourne, Royal Melbourne Hospital, Charles Connibere Building, Melbourne, Victoria, Australia
    Osteoporos Int 15:881-6. 2004
    ..The aim of this study was to assess the relative strength of the association of endogenous estradiol and androgens with bone loss at the lumbar spine and femoral neck during the menopausal transition...
  15. doi request reprint Effects of a targeted multimodal exercise program incorporating high-speed power training on falls and fracture risk factors in older adults: a community-based randomized controlled trial
    Jenny Gianoudis
    NorthWest Academic Centre, University of Melbourne, Western Health, Melbourne, Australia Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Deakin University, Melbourne, Australia
    J Bone Miner Res 29:182-91. 2014
    ..Although this did not translate into a reduction in the rate of falls, further large-scale trials are needed to evaluate the efficacy of this multimodal approach on reducing falls and fracture...
  16. ncbi request reprint Vitamin D and health in adults in Australia and New Zealand: a position statement
    Caryl A Nowson
    Centre for Physical Activity and Nutrition Research, Deakin University, Melbourne, Vic
    Med J Aust 196:686-7. 2012
    ..People in high-risk groups may require higher doses. There is good evidence that vitamin D plus calcium supplementation effectively reduces fractures and falls in older men and women...
  17. doi request reprint Secondary causes of low bone mass in patients with breast cancer: a need for greater vigilance
    G Bruce Mann
    Royal Women s Hospital, Parkville, Victoria, 3052, Australia
    J Clin Oncol 27:3605-10. 2009
    ..An observational study to assess the prevalence of secondary causes of low bone density in patients with breast cancer...
  18. pmc Osteo-cise: strong bones for life: protocol for a community-based randomised controlled trial of a multi-modal exercise and osteoporosis education program for older adults at risk of falls and fractures
    Jenny Gianoudis
    NorthWest Academic Centre, Department of Medicine, University of Melbourne, Western Health, Melbourne, Australia
    BMC Musculoskelet Disord 13:78. 2012
    ..Thus, there is a need to develop evidence-based, safe and acceptable prevention strategies at the population level that target multiple risk factors for fragility fractures to reduce the health and economic burden of the condition...
  19. ncbi request reprint Decreased spinal and femoral neck volumetric bone mineral density (BMD) in men with primary osteoporosis and their first-degree male relatives: familial effect on BMD in men
    Bircan Erbas
    Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, University of Melbourne, Parkville, Australia
    Clin Endocrinol (Oxf) 66:78-84. 2007
    ..The purpose of this study was to examine differences in bone volume and volumetric bone mineral density (vBMD) in men with primary osteoporosis and their first-degree male relatives (FDMR)...
  20. doi request reprint Is high dose vitamin D harmful?
    Kerrie M Sanders
    Department of Medicine, Western Health, NorthWest Academic Centre, University of Melbourne, PO Box 294, St Albans, Vic, 3021, Australia
    Calcif Tissue Int 92:191-206. 2013
    ..The current dilemma of defining vitamin D insufficiency and identifying safe and efficacious repletion regimens needs to be resolved...
  21. doi request reprint Lack of sustained response to teriparatide in a patient with adult hypophosphatasia
    Claudia Gagnon
    Department of Medicine, University of Melbourne, Western Hospital, Footscray Vic 3011, Australia
    J Clin Endocrinol Metab 95:1007-12. 2010
    ..In contrast to the two previously reported cases, biochemical response to teriparatide was unsustained, suggesting that response may be variable depending on the TNSALP gene mutation...
  22. doi request reprint Social determinants of bone densitometry uptake for osteoporosis risk in patients aged 50yr and older: a systematic review
    Sharon L Brennan
    Department of Medicine, NorthWest Academic Centre, The University of Melbourne, Sunshine Hospital, St Albans, Victoria, Australia
    J Clin Densitom 15:165-75. 2012
    ....
  23. ncbi request reprint When continuity of care breaks down: a systems failure in identification of osteoporosis risk in older patients treated for minimal trauma fractures
    Anne Maree Kelly
    Joseph Epstein Centre for Emergency Medicine Research, Western Health, Melbourne, Vic
    Med J Aust 188:389-91. 2008
    ..Our aim was to determine the proportion of patients who underwent bone density testing for osteoporosis of those with a minimal trauma wrist fracture treated in the emergency department (ED)...
  24. ncbi request reprint Efficacy and safety of oral continuous low-dose versus short-term high-dose vitamin D: a prospective randomised trial conducted in a clinical setting
    Kathryn L Hackman
    Department of Medicine, University of Melbourne, Melbourne, Vic, Australia
    Med J Aust 192:686-9. 2010
    ..The primary end points were the change in serum 25-hydroxyvitamin D (25(OH)D) concentrations at 3 months and the development of hypercalcaemia and hypercalciuria...
  25. doi request reprint A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine
    John R Sheedy
    Department of Medicine, Royal Melbourne and Western Hospitals, University of Melbourne, Footscray, Victoria 3011, Australia
    Anal Biochem 398:263-5. 2010
    ..The efficacy of this protocol was tested using a bovine serum albumin/metabolite mix and human serum samples. This sample preparation method can be readily applied to any protein-containing biofluid for (1)H NMR studies...
  26. doi request reprint Effect of vitamin D supplementation on antibiotic use: a randomized controlled trial
    Bich Tran
    Population Health Department, Queensland Institute of Medical Research, Brisbane, Queensland, Australia BT, DCW, PMW, and REN the Centre for Research Excellence in Sun and Health, Queensland University of Technology, Kelvin Grove, Queensland, Australia BT, MGK, DCW, and REN the School of Population Health, University of Queensland, Brisbane, Queensland, Australia JCvdP the Sydney School of Public Health BKA and the National Health and Medical Research Council of Australia Clinical Trials Centre, Sydney Medical School VG, University of Sydney, Camperdown, New South Wales, Australia Northwest Academic Centre, University of Melbourne, and Western Health, Melbourne, Victoria, Australia PRE the School of Population Health, University of Melbourne, Parkville, Victoria, Australia DRE the AusSun Research Laboratory, Queensland University of Technology, Kelvin Grove, Queensland, Australia MGK and the Menzies Research Institute Tasmania, Hobart, Tasmania, Australia AV
    Am J Clin Nutr 99:156-61. 2014
    ..Observational data suggested that supplementation with vitamin D could reduce risk of infection, but trial data are inconsistent...
  27. ncbi request reprint Suburban clustering of vitamin D deficiency in Melbourne, Australia
    Bircan Erbas
    Centre for Molecular Environmental Genetic Analytic Epidemiology, School of Population Health, University of Melbourne, Carlton, Victoria, Australia
    Asia Pac J Clin Nutr 17:63-7. 2008
    ..Vitamin D status of women with differ-ing age and ethnic distributions residing in other suburbs is unknown...
  28. doi request reprint Investigating the predictive ability of gait speed and quadriceps strength for incident falls in community-dwelling older women at high risk of fracture
    David Scott
    NorthWest Academic Centre, The University of Melbourne, Western Health, St Albans, Victoria, Australia Electronic address
    Arch Gerontol Geriatr 58:308-13. 2014
    ..Quadriceps strength tests may be an acceptable alternative to gait speed for geriatric assessments of falls risk. ..
  29. pmc Is excess calcium harmful to health?
    Robin M Daly
    Department of Medicine, The University of Melbourne, Western Hospital, Melbourne 3011, Australia
    Nutrients 2:505-22. 2010
    ....
  30. pmc Serum 25-hydroxyvitamin D, calcium intake, and risk of type 2 diabetes after 5 years: results from a national, population-based prospective study (the Australian Diabetes, Obesity and Lifestyle study)
    Claudia Gagnon
    Department of Medicine, NorthWest Academic Centre, The University of Melbourne, Western Hospital, Melbourne, Australia
    Diabetes Care 34:1133-8. 2011
    ..To examine whether serum 25-hydroxyvitamin D (25OHD) and dietary calcium predict incident type 2 diabetes and insulin sensitivity...
  31. doi request reprint A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures
    Rachelle Buchbinder
    Monash Department of Clinical Epidemiology, Cabrini Hospital, and Monash University, Malvern, Vic, Australia
    N Engl J Med 361:557-68. 2009
    ..Vertebroplasty has become a common treatment for painful osteoporotic vertebral fractures, but there is limited evidence to support its use...
  32. pmc Osteoporosis in men: its pathophysiology and the role of teriparatide in its treatment
    Claudia Gagnon
    Department of Medicine, The University of Melbourne, Western Hospital, Cnr Eleanor and Marion Streets, Footscray, VIC 3011, Australia
    Clin Interv Aging 3:635-45. 2008
    ..Furthermore, the evidence supporting the efficacy of teriparatide treatment in men with osteoporosis is reviewed and its current role in the management of osteoporosis in men is discussed...
  33. doi request reprint Vitamin d deficiency and its role in muscle-bone interactions in the elderly
    Kerrie M Sanders
    NorthWest Academic Centre, The University of Melbourne, St Albans, Victoria, Australia, 3021
    Curr Osteoporos Rep 12:74-81. 2014
    ....
  34. ncbi request reprint Central abdominal fat and endogenous hormones during the menopausal transition
    Janet R Guthrie
    Office for Gender and Health, Royal Melbourne Hospital, Victoria, Australia
    Fertil Steril 79:1335-40. 2003
    ..To investigate the effect of endogenous hormone levels on central abdominal fat during the menopausal transition in a population-based cohort of Australian-born women...
  35. pmc Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner
    Tania J Fernandes
    NorthWest Academic Centre, Department of Medicine, The University of Melbourne, Victoria, Australia Barwon Biomedical Research, The Geelong Hospital, Geelong, Victoria, Australia
    PLoS ONE 8:e73266. 2013
    ..This supports the notion that eliciting gp130-dependent signals in human MSC would be a useful approach to increase bone formation. ..
  36. doi request reprint Oral health risk factors for bisphosphonate-associated jaw osteonecrosis
    Claudine Tsao
    Oral Health CRC and Melbourne Dental School, University of Melbourne, Melbourne, Australia
    J Oral Maxillofac Surg 71:1360-6. 2013
    ..To investigate the role of oral health, including periodontitis, as a risk factor for bisphosphonate-associated jaw osteonecrosis (ONJ)...
  37. doi request reprint An atypical subtrochanteric femoral fracture from pycnodysostosis: a lesson from nature
    Christopher J Yates
    Endocrinology Unit, University of Melbourne, Western Hospital, Footscray, Victoria, Australia
    J Bone Miner Res 26:1377-9. 2011
    ..Therefore, there should be vigilant monitoring for the development of long-term complications noted to occur in diseases of reduced osteoclast function, including pycnodysostosis, in patients receiving these novel antiresorptive agents...
  38. ncbi request reprint Relationship between bone markers and knee cartilage volume in healthy men
    Yuanyuan Wang
    Department of Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Australia
    J Rheumatol 32:2200-4. 2005
    ..To determine the relationship between biochemical bone markers and knee cartilage volume and cartilage loss over 2 years; and to investigate whether bone markers are useful to predict the cartilage loss in healthy men...
  39. ncbi request reprint The relationship between body composition and knee cartilage volume in healthy, middle-aged subjects
    Flavia M Cicuttini
    Monash University Medical School, Alfred Hospital, Prahran, Australia
    Arthritis Rheum 52:461-7. 2005
    ..This study examined the effect of measures of body composition on the longitudinal change in tibial cartilage volume...
  40. ncbi request reprint Defective osteoblast function may be responsible for bone loss from the proximal femur despite pamidronate therapy
    Peter R Ebeling
    J Clin Endocrinol Metab 90:4414-6. 2005
  41. ncbi request reprint Editorial: inhibin in bone--new tricks for an old dog
    Peter R Ebeling
    J Clin Endocrinol Metab 91:1669-70. 2006
  42. ncbi request reprint Megadose therapy for vitamin D deficiency
    Peter R Ebeling
    Med J Aust 183:4-5. 2005
  43. ncbi request reprint Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
    Sundeep Khosla
    J Bone Miner Res 22:1479-91. 2007
    ..This report summarizes the findings and recommendations of the task force...
  44. ncbi request reprint Positive effects of intravenous zoledronic acid on bone remodeling and structure: are different effects on osteoblast activity to other oral bisphosphonates responsible?
    Peter R Ebeling
    J Bone Miner Res 23:2-5. 2008
  45. doi request reprint Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment
    Sundeep Khosla
    J Oral Maxillofac Surg 66:1320-1; author reply 1321-2. 2008
  46. ncbi request reprint The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women
    Fabien S Dalais
    Department of Epidemiology and Preventive Medicine, Monash University, The Alfred Hospital, Prahran, Australia
    Clin Endocrinol (Oxf) 58:704-9. 2003
    ..To assess the effect of a dietary soy protein supplement containing isoflavones on lipids and indices of bone resorption in postmenopausal women...
  47. ncbi request reprint Preventing osteoporosis: outcomes of the Australian Fracture Prevention Summit
    Philip N Sambrook
    Med J Aust 176:S1-16. 2002
  48. doi request reprint Randomized controlled trial of the effects of calcium with or without vitamin D on bone structure and bone-related chemistry in elderly women with vitamin D insufficiency
    Kun Zhu
    School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
    J Bone Miner Res 23:1343-8. 2008
    ..Vitamin D supplementation adds no extra short-term skeletal benefit to calcium citrate supplementation even in women with vitamin D insufficiency...