M J Eadie

Summary

Affiliation: University of Queensland
Country: Australia

Publications

  1. ncbi request reprint Antiepileptic drugs as human teratogens
    Mervyn J Eadie
    University of Queensland, and Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia 4029, Australia
    Expert Opin Drug Saf 7:195-209. 2008
  2. doi request reprint Shortcomings in the current treatment of epilepsy
    Mervyn J Eadie
    Faculty of Health Sciences, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, QLD 4027, Australia
    Expert Rev Neurother 12:1419-27. 2012
  3. doi request reprint Sir Charles Locock and potassium bromide
    M J Eadie
    Faculty of Health Sciences, University of Queensland, Royal Brisbane and Women s Hospital, Australia
    J R Coll Physicians Edinb 42:274-9. 2012
  4. doi request reprint William Gowers: the never completed third edition of the 'Bible of Neurology'
    Mervyn J Eadie
    Faculty of Health Sciences, University of Queensland, Brisbane 4027, Australia
    Brain 135:3178-88. 2012
  5. ncbi request reprint Absinthe, epileptic seizures and Valentin Magnan
    M J Eadie
    University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 39:73-8. 2009
  6. ncbi request reprint The neurological legacy of John Russell Reynolds (1828-1896)
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Herston, 4029, Queensland, Australia
    J Clin Neurosci 14:309-16. 2007
  7. doi request reprint Experimental epileptology before 1900
    Mervyn J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    Epilepsia 50:377-386. 2009
  8. doi request reprint Samuel Wilks (1824-1911): neurologist and generalist of the Mid-Victorian Era
    Mervyn J Eadie
    Department of Medicine, Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    J Med Biogr 16:215-20. 2008
  9. ncbi request reprint Marshall Hall, the reflex arc and epilepsy
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 38:167-71. 2008
  10. ncbi request reprint The epileptology of John Thompson Dickson (1841-1874)
    Mervyn Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    Epilepsia 48:23-30. 2007

Detail Information

Publications46

  1. ncbi request reprint Antiepileptic drugs as human teratogens
    Mervyn J Eadie
    University of Queensland, and Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia 4029, Australia
    Expert Opin Drug Saf 7:195-209. 2008
    ..There is still uncertainty concerning the risk of fetal malformation associated with the intake of various individual antiepileptic drugs in pregnant women...
  2. doi request reprint Shortcomings in the current treatment of epilepsy
    Mervyn J Eadie
    Faculty of Health Sciences, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, QLD 4027, Australia
    Expert Rev Neurother 12:1419-27. 2012
    ....
  3. doi request reprint Sir Charles Locock and potassium bromide
    M J Eadie
    Faculty of Health Sciences, University of Queensland, Royal Brisbane and Women s Hospital, Australia
    J R Coll Physicians Edinb 42:274-9. 2012
    ..The drug might not have come into more widespread use as a result, had not Samuel Wilks provided good, independent evidence for the drug's antiepileptic efficacy in 1861...
  4. doi request reprint William Gowers: the never completed third edition of the 'Bible of Neurology'
    Mervyn J Eadie
    Faculty of Health Sciences, University of Queensland, Brisbane 4027, Australia
    Brain 135:3178-88. 2012
    ....
  5. ncbi request reprint Absinthe, epileptic seizures and Valentin Magnan
    M J Eadie
    University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 39:73-8. 2009
    ..Whether that component, presumably thujone, was present at convulsant concentrations in some of the available absinthes of Magnan's time cannot now be known...
  6. ncbi request reprint The neurological legacy of John Russell Reynolds (1828-1896)
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Herston, 4029, Queensland, Australia
    J Clin Neurosci 14:309-16. 2007
    ....
  7. doi request reprint Experimental epileptology before 1900
    Mervyn J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    Epilepsia 50:377-386. 2009
    ..Nevertheless, the pre-1900 investigations not only laid the foundations for the 20th Century expansion of experimental studies on epileptogenesis but also advanced the understanding of epileptic seizure production...
  8. doi request reprint Samuel Wilks (1824-1911): neurologist and generalist of the Mid-Victorian Era
    Mervyn J Eadie
    Department of Medicine, Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    J Med Biogr 16:215-20. 2008
    ..He provided possibly the first account of alcoholic peripheral neuritis and published an early account of probable myasthenia gravis...
  9. ncbi request reprint Marshall Hall, the reflex arc and epilepsy
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 38:167-71. 2008
    ..However, from 1870 onwards it was superseded by John Hughlings Jackson's accumulating evidence that epileptic seizures often arose in the cerebral cortex...
  10. ncbi request reprint The epileptology of John Thompson Dickson (1841-1874)
    Mervyn Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Brisbane, Australia
    Epilepsia 48:23-30. 2007
    ..To document John Thompson Dickson's interpretation of epileptogenesis, published between 1869 and 1874, and to compare it with John Hughlings Jackson's contemporaneous thought...
  11. doi request reprint The role of focal epilepsy in the development of jacksonian localization
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Australia
    J Hist Neurosci 18:262-82. 2009
    ....
  12. ncbi request reprint Hubert Airy, contemporary men of science and the migraine aura
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 39:263-7. 2009
    ..Subsequently, migraine with aura quickly became a well-recognised clinical entity in British medicine...
  13. doi request reprint The idea of epilepsy as a disease per se
    Mervyn J Eadie
    Central Clinical School University of Queensland, Royal Brisbane and Women s Hospital, Herston, Australia 4027
    J Hist Neurosci 19:209-20. 2010
    ..With increasing identification of structural brain pathology in what had been regarded as instances of idiopathic epilepsy, the latter view has increasingly prevailed...
  14. doi request reprint William Gowers' interpretation of epileptogenic mechanisms: 1880-1906
    Mervyn J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Herston, Queensland, Australia
    Epilepsia 52:1045-51. 2011
    ..He settled on the synaptic gap as its likely site. However, the inhibition mechanism that he proposed, namely, retraction of dendrites, was rather extraordinary in the light of subsequent knowledge...
  15. ncbi request reprint James Ross (1837-1892) and his forgotten neurology textbook of 1881
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Australia
    J R Coll Physicians Edinb 40:263-8. 2010
    ....
  16. doi request reprint Louis François Bravais and Jacksonian epilepsy
    Mervyn Eadie
    Central Clinical School, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Queensland 4027, Australia
    Epilepsia 51:1-6. 2010
    ..Although Bravais had the priority, his work went largely unnoticed until Jackson's insights had made their impact on medical thinking...
  17. ncbi request reprint Rigor mortis and the epileptology of Charles Bland Radcliffe (1822-1889)
    M J Eadie
    Central Clinical School, University of Queensland, Royal Brisbane Hospital, Herston, Herston Road, Brisbane, 4027, Australia
    J Clin Neurosci 14:201-7. 2007
    ..As well, Radcliffe was one of the chief early advocates for potassium bromide, the first effective anticonvulsant...
  18. ncbi request reprint Effect of naproxen co-administration on valproate disposition
    R S Addison
    Centre for Studies in Drug Disposition, The University of Queensland, Clinical Sciences Building, Royal Brisbane Hospital, Queensland, Australia
    Biopharm Drug Dispos 21:235-42. 2000
    ....
  19. ncbi request reprint Plasma antiepileptic drug concentrations during pregnancy
    C M Lander
    Department of Neurology, Royal Brisbane Hospital, Herston, Australia
    Epilepsia 32:257-66. 1991
    ..This may have occurred because some patients were seen too late in their pregnancies for the policy to have been applied optimally...
  20. ncbi request reprint A pathology of the animal spirits -- the clinical neurology of Thomas Willis (1621-1675). Part II -- disorders of intrinsically abnormal animal spirits
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Australia
    J Clin Neurosci 10:146-57. 2003
    ....
  21. ncbi request reprint Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Australia
    Clin Pharmacokinet 21:27-41. 1991
    ....
  22. ncbi request reprint Anticonvulsant therapy in aged patients. Clinical pharmacokinetic considerations
    I Bernus
    Conjoint Endocrine Laboratory, Royal Brisbane Hospital, Queensland, Australia
    Drugs Aging 10:278-89. 1997
    ..Thus. the clearances of vigabatrin and gabapentin correlate with creatinine clearance. Such considerations may help guide anticonvulsant dosage in the elderly...
  23. ncbi request reprint The epileptology of William Aldren Turner
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Queensland, Australia
    J Clin Neurosci 13:9-13. 2006
    ....
  24. ncbi request reprint Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy
    Frank J Vajda
    Department of Medicine, The Australian Centre For Neuropharmacology, Raoul Wallenberg Centre, St Vincent s Hospital, Fitzroy, 3065 Melbourne, Vic, Australia
    J Clin Neurosci 11:854-8. 2004
    ..A prospective, observational, community-based cohort study...
  25. ncbi request reprint Steady-state dispositions of valproate and diflunisal alone and coadministered to healthy volunteers
    R S Addison
    Centre for Studies in Drug Disposition, The University of Queensland, Royal Brisbane Hospital, Australia
    Eur J Clin Pharmacol 56:715-21. 2000
    ....
  26. ncbi request reprint The effect of body size on the metabolic clearance of carbamazepine
    D M Reith
    Royal Children s Hospital, Herston Rd, Herston, Queensland, Australia
    Biopharm Drug Dispos 21:103-11. 2000
    ..To examine the profile of the known pathways of carbamazepine (CBZ) metabolism in a group of children and adolescents, and to test for associations with physical measurements, age and plasma hormonal levels...
  27. ncbi request reprint The pathogenesis of migraine - 17th to early 20th century understandings
    M J Eadie
    Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    J Clin Neurosci 12:383-8. 2005
    ..No hypothesis has yet proved capable of explaining all the features of migraine satisfactorily...
  28. ncbi request reprint The antiepileptic Materia Medica of Pediacus Dioscorides
    M J Eadie
    Department of Medicine, University of Queensland, Herston, Brisbane 4029, Australia
    J Clin Neurosci 11:697-701. 2004
    ..The stones, or one of them, were worn against the skin of the seizure sufferer. The use of the swallow stones for epilepsy was recommended as late as in the writings of Thomas Willis (1675)...
  29. ncbi request reprint Clinically significant drug interactions with agents specific for migraine attacks
    M J Eadie
    Department of Medicine, University of Queensland, Royal Brisbane Hospital, Australia
    CNS Drugs 15:105-18. 2001
    ..In contrast, new interactions involving the triptans are likely to be recognised as additional members of this family of drugs, with their different patterns of metabolism and pharmacokinetics, are marketed...
  30. ncbi request reprint Alfred Walter Campbell (1868-1937)
    M J Eadie
    University of Queensland Ladhope Chambers 131 Wickham Terrace Brisbane 400, Australia
    J Neurol 250:249-50. 2003
  31. ncbi request reprint The epileptology of Théodore Herpin (1799-1865)
    Mervyn J Eadie
    Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    Epilepsia 43:1256-61. 2002
    ....
  32. doi request reprint Utilization of anti-Parkinson drugs in Australia: 1995-2009
    Samantha A Hollingworth
    The University of Queensland, School of Population Health, Herston, Australia
    Pharmacoepidemiol Drug Saf 20:450-6. 2011
    ..To examine trends in the prescribing of anti-Parkinsonian drugs (APD) in Australia from 1995 to 2009...
  33. ncbi request reprint Cortical epileptogenesis--Hughlings Jackson and his predecessors
    Mervyn J Eadie
    Department of Medicine Royal Brisbane Hospital, Central Clinical School, University of Queensland, Brisbane, Australia
    Epilepsia 48:2010-5. 2007
    ..To trace the concept that the cerebral cortex is the site of epileptogenesis before Hughlings Jackson published the idea in 1870 in the paper "A study of convulsions" which marks the beginning of modern epileptology...
  34. ncbi request reprint Could valerian have been the first anticonvulsant?
    Mervyn J Eadie
    Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    Epilepsia 45:1338-43. 2004
    ..To assess the available evidence for the belief that valerian, highly recommended in the past for treating epilepsy, possessed real anticonvulsant effectiveness...
  35. doi request reprint Antiepileptic drugs in Australia: 2002-2007
    Samantha A Hollingworth
    School of Population Health, University of Queensland, Herston, QLD 4006, Australia
    Pharmacoepidemiol Drug Saf 19:82-9. 2010
    ..We examined the trends in the prescribing of subsidised AEDs in the Australian population from 2002 to 2007...
  36. ncbi request reprint A pathology of the animal spirits -- the clinical neurology of Thomas Willis (1621-1675) part I -- background, and disorders of intrinsically normal animal spirits
    M J Eadie
    Department of Medicine, University of Queensland
    J Clin Neurosci 10:14-29. 2003
    ..The disorders he attributed to inherently abnormal animal spirits are considered in a second part of the paper...
  37. ncbi request reprint Convulsive ergotism: epidemics of the serotonin syndrome?
    Mervyn J Eadie
    Department of Medicine, University of Queensland, and the Royal Brisbane Hospital, Brisbane, Australia
    Lancet Neurol 2:429-34. 2003
    ..The serotonin syndrome may, therefore, have been a public-health problem long before it was recognised as a complication of modern psychopharmacology...
  38. ncbi request reprint Urinary excretion of valproate metabolites in children and adolescents
    D M Reith
    Royal Children s Hospital, Brisbane, Queensland 4029, Australia
    Biopharm Drug Dispos 21:327-30. 2000
    ..001 versus p<0.05). In conclusion, older children and adolescents, when compared with younger children, and those comedicated with LTG excrete a higher proportion of VPA dose as VPA-glucuronide...
  39. ncbi request reprint The single seizure. To treat or not to treat?
    M J Eadie
    Department of Clinical Neurology and Neuropharmacology, University of Queensland, Brisbane, Australia
    Drugs 54:651-6. 1997
    ..Unless a further seizure would hold little disadvantage, early treatment probably offers distinctly more benefit than hazard. No data are available to indicate the most appropriate duration of therapy after a single seizure...
  40. ncbi request reprint Ergot of rye-the first specific for migraine
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Australia
    J Clin Neurosci 11:4-7. 2004
    ....
  41. pmc Therapeutic drug monitoring--antiepileptic drugs
    M J Eadie
    Department of Medicine, University of Queensland, Brisbane, Australia
    Br J Clin Pharmacol 52:11S-20S. 2001
    ....
  42. ncbi request reprint Can anticonvulsant drug therapy "cure" epilepsy?
    M J Eadie
    Department of Medicine, University of Queensland, 131 Wickham Tce, Brisbane, Queensland 4000, Australia
    CNS Drugs 15:679-90. 2001
    ..Therefore it would appear premature to take the view that contemporary anticonvulsant drug therapy does no more than suppress epileptic seizures until epilepsy remits spontaneously, or fails to remit, with the passing of time...
  43. ncbi request reprint A.W. Campbell's Australian career: 1905-1937
    M J Eadie
    University of Medicine, University of Queensland, Brisbane, Australia
    J Clin Neurosci 8:514-9. 2001
    ..Campbell's circumstances in Sydney, his extremely reticent nature and the essentially negative outcome of his investigation probably explain his failure to make his study more widely known...
  44. ncbi request reprint Victor Horsley's contribution to Jacksonian epileptology
    Mervyn J Eadie
    Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia
    Epilepsia 46:1836-40. 2005
    ..To describe Victor Horsley's contribution to John Hughlings Jackson's understanding of the mechanisms involved in the generalization of convulsive epileptic seizures...
  45. ncbi request reprint Monitoring salivary lamotrigine concentrations
    Stephen A Malone
    Royal Children s Hospital, Brisbane, Queensland, Australia
    J Clin Neurosci 13:902-7. 2006
    ..This has significant implications for the elucidation of the pharmacokinetics of lamotrigine in the paediatric population...
  46. ncbi request reprint Withdrawal of methylphenobarbitone
    Mervyn J Eadie
    Med J Aust 178:44. 2003