Research Topics
| Gursharan K DograSummaryAffiliation: University of Western Australia Country: Australia Publications
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Detail Information
Publications
Statin therapy improves brachial artery endothelial function in nephrotic syndromeGursharan K Dogra
Department of Medicine and Western Australian Heart Research Institute, University of Western Australia, Australia
Kidney Int 62:550-7. 2002..Patients with nephrotic syndrome have impaired endothelial function probably related to dyslipidemia. This study evaluated the effects of statin therapy on dyslipidemia and endothelial function in patients with nephrotic syndrome...
Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: a randomized controlled studyGursharan K Dogra
Department of Medicine, University of Western Australia, Perth, Western Australia
J Am Soc Nephrol 13:2133-9. 2002..Before this technique is adopted, these preliminary observations warrant replication in future studies that will examine the efficacy and safety of lower doses of gentamicin or alternative agents with a reduced potential for toxicity...
Insulin resistance, dyslipidaemia, inflammation and endothelial function in nephrotic syndromeGursharan K Dogra
Department of Medicine and Western Australian Heart Research Institute, University of Western Australia, Perth, Western Australia, Australia
Nephrol Dial Transplant 17:2220-5. 2002..In this study our aim was to assess the potential roles of insulin resistance, plasma non-esterified fatty acids (NEFAs) and inflammation in endothelial dysfunction in NS patients...
Statin therapy improves brachial artery vasodilator function in patients with Type 1 diabetes and microalbuminuriaG K Dogra
School of Medicine and Pharmacology, Royal Perth Hospital Unit, Western Australian Heart Research Institute, University of Western Australia, Perth, Western Australia
Diabet Med 22:239-42. 2005..We therefore examined the effects of atorvastatin on brachial artery endothelial dysfunction in these patients...
Rosiglitazone does not improve vascular function in subjects with chronic kidney diseaseDoris T Chan
School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia, Perth, Australia
Nephrol Dial Transplant 26:3543-9. 2011..This study examines the effect of RSG on vascular function in patients with CKD...
Plasma apolipoprotein C-III metabolism in patients with chronic kidney diseaseEsther M M Ooi
Metabolic Research Centre, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
J Lipid Res 52:794-800. 2011..05 for all). Altered plasma apoC-III metabolism is a feature of dyslipidemia in moderate CKD. Modification of apoC-III catabolism may be an important therapeutic target for reducing cardiovascular disease risk in moderate CKD...
Dyslipidaemia and cardiorenal disease: mechanisms, therapeutic opportunities and clinical trialsDoris T Chan
Metabolic Research Centre, School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia 6000, Australia
Atherosclerosis 196:823-34. 2008..Because of increased risk of toxicity, particularly myopathy, statins and other lipid-regulating agents should be used cautiously in CKD and renal transplant recipients...
Vascular function of the peripheral circulation in patients with nephrosisG F Watts
Department of Medicine and Western Australian Heart Research Institute, University of Western Australia, Australia
Kidney Int 60:182-9. 2001..Endothelial dysfunction, an early phase of atherogenesis that manifests as impaired flow-mediated dilation (FMD) of the peripheral circulation, may link these associations...
Chronic kidney disease delays VLDL-apoB-100 particle catabolism: potential role of apolipoprotein C-IIIDoris T Chan
School of Medicine Pharmacology, Royal Perth Hospital Unit, University of Western Australia, WA, Australia
J Lipid Res 50:2524-31. 2009..Altered apoC-III metabolism may contribute to dyslipidemia in CKD, and this requires further investigation...
Compared with younger peritoneal dialysis patients, elderly patients have similar peritonitis-free survival and lower risk of technique failure, but higher risk of peritonitis-related mortalityWai H Lim
Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, SA, Australia
Perit Dial Int 31:663-71. 2011..The reluctance of elderly ESKD patients to consider PD may be related to a perception that PD is associated with greater rates of complications. In the present study, we compared outcomes between younger and older PD patients...
