P G Dinning

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. doi request reprint Bowel preparation affects the amplitude and spatiotemporal organization of colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 22:633-e176. 2010
  2. doi request reprint Spatio-temporal analysis reveals aberrant linkage among sequential propagating pressure wave sequences in patients with symptomatically defined obstructed defecation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 21:945-e75. 2009
  3. doi request reprint Technical advances in monitoring human motility patterns
    P G Dinning
    University of New South Wales, Department of Gastroenterology, St George Hospital, Sydney, Australia
    Neurogastroenterol Motil 22:366-80. 2010
  4. doi request reprint Determinants of postprandial flow across the human ileocaecal junction: a combined manometric and scintigraphic study
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1119-26. 2008
  5. doi request reprint Twenty-four hour spatiotemporal mapping of colonic propagating sequences provides pathophysiological insight into constipation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1017-21. 2008
  6. doi request reprint Proximal colonic propagating pressure waves sequences and their relationship with movements of content in the proximal human colon
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia
    Neurogastroenterol Motil 20:512-20. 2008
  7. doi request reprint Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation
    P G Dinning
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 22:e340-9. 2010
  8. ncbi request reprint Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defecation frequency in patients with slow-transit constipation
    P G Dinning
    Department of Medicine, University of New South Wales, Sydney, Australia
    Colorectal Dis 9:123-32. 2007
  9. doi request reprint Temporal relationships between wall motion, intraluminal pressure, and flow in the isolated rabbit small intestine
    P G Dinning
    St George Clinical School, University of New South Wales, Australia
    Am J Physiol Gastrointest Liver Physiol 300:G577-85. 2011
  10. doi request reprint Colonic dysmotility in constipation
    Philip G Dinning
    Department of Gastroenterology, University of New South Wales, St George Hospital, Gray St, Kogarah, NSW 2217, Sydney, Australia
    Best Pract Res Clin Gastroenterol 25:89-101. 2011

Detail Information

Publications24

  1. doi request reprint Bowel preparation affects the amplitude and spatiotemporal organization of colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 22:633-e176. 2010
    ..There has been little systematic evaluation of the effects of bowel cleansing upon colonic propagating pressure wave sequences...
  2. doi request reprint Spatio-temporal analysis reveals aberrant linkage among sequential propagating pressure wave sequences in patients with symptomatically defined obstructed defecation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 21:945-e75. 2009
    ..Regional linkage may be important for normal colonic transit and loss of linkage might have pathophysiological relevance to and provide a useful biomarker of severe constipation...
  3. doi request reprint Technical advances in monitoring human motility patterns
    P G Dinning
    University of New South Wales, Department of Gastroenterology, St George Hospital, Sydney, Australia
    Neurogastroenterol Motil 22:366-80. 2010
    ..This review highlights a range of these recent developments and examines their potential to help diagnose and guide treatment for motility disorders...
  4. doi request reprint Determinants of postprandial flow across the human ileocaecal junction: a combined manometric and scintigraphic study
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1119-26. 2008
    ..We conclude that ileal PSs are highly propulsive and are the major determinant of episodic caecal filling and that caecal filling may be a major stimulus for caecal propagating sequences...
  5. doi request reprint Twenty-four hour spatiotemporal mapping of colonic propagating sequences provides pathophysiological insight into constipation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1017-21. 2008
    ..Such graphical representation readily permits appreciation and identification of aberrant patterns in severe constipation and may be an important clinical and research tool in the assessment of colonic motor disorders...
  6. doi request reprint Proximal colonic propagating pressure waves sequences and their relationship with movements of content in the proximal human colon
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia
    Neurogastroenterol Motil 20:512-20. 2008
    ..We conclude that proximal colonic PSs are highly propulsive and are a major determinant of proximal colonic flow...
  7. doi request reprint Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation
    P G Dinning
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 22:e340-9. 2010
    ..Utilizing the technique of spatiotemporal mapping, we aimed to demonstrate 'manometric signatures' that may serve as biomarkers of the disorder...
  8. ncbi request reprint Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defecation frequency in patients with slow-transit constipation
    P G Dinning
    Department of Medicine, University of New South Wales, Sydney, Australia
    Colorectal Dis 9:123-32. 2007
    ..The effects of SNS on colonic propagating sequences in constipation are unknown. Our aims were to evaluate the effect of SNS on colonic pressure patterns and evaluate its therapeutic potential in severe constipation...
  9. doi request reprint Temporal relationships between wall motion, intraluminal pressure, and flow in the isolated rabbit small intestine
    P G Dinning
    St George Clinical School, University of New South Wales, Australia
    Am J Physiol Gastrointest Liver Physiol 300:G577-85. 2011
    ..Studies of wall motion in isolated preparations, combined with manometry, can assist in interpretation of pressure recordings in vivo...
  10. doi request reprint Colonic dysmotility in constipation
    Philip G Dinning
    Department of Gastroenterology, University of New South Wales, St George Hospital, Gray St, Kogarah, NSW 2217, Sydney, Australia
    Best Pract Res Clin Gastroenterol 25:89-101. 2011
    ..The scope of this review encompasses the latest findings that improve our understanding of the motility disorders associated with colonic dysfunction in both the paediatric and adult population suffering from constipation...
  11. pmc Factor analysis identifies subgroups of constipation
    Philip G Dinning
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    World J Gastroenterol 17:1468-74. 2011
    ..To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction...
  12. pmc Pathophysiology of colonic causes of chronic constipation
    P G Dinning
    Department of Medicine, University of New South Wales, St George Hospital, Sydney, Australia
    Neurogastroenterol Motil 21:20-30. 2009
    ..This review addresses current understanding derived from both human and animal studies, with particular reference made to methods of investigation...
  13. ncbi request reprint Prolonged multi-point recording of colonic manometry in the unprepared human colon: providing insight into potentially relevant pressure wave parameters
    P A Bampton
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, Australia
    Am J Gastroenterol 96:1838-48. 2001
    ..The study demonstrates differences between high amplitude propagating sequences and propagating sequence parameters that may have functional significance; and also, that the rectal motor complex is a ubiquitous pan colonic motor pattern...
  14. doi request reprint Intraluminal impedance detects failure of pharyngeal bolus clearance during swallowing: a validation study in adults with dysphagia
    M M Szczesniak
    Department of Gastroenterology, University of NSW and St George Hospital, Sydney, NSW, Australia
    Neurogastroenterol Motil 21:244-52. 2009
    ..62 in the proximal oesophagus. With the adoption of appropriate criteria, pharyngeal impedance measurement can accurately detect bolus passage and failed or impaired clearance during swallowing in patients with dysphagia...
  15. doi request reprint Low-resolution colonic manometry leads to a gross misinterpretation of the frequency and polarity of propagating sequences: Initial results from fiber-optic high-resolution manometry studies
    P G Dinning
    Departments of Gastroenterology and Surgery, Flinders Medical Centre, Flinders University, South Australia, Australia School of Medicine, University of New South Wales, New South Wales, Australia
    Neurogastroenterol Motil 25:e640-9. 2013
    ..High-resolution manometry catheters are now being used to record colonic motility. The aim of this study was to determine the influence of pressure sensor spacing on our ability to identify colonic propagating sequences (PS)...
  16. doi request reprint Classification of normal and abnormal colonic motility based on cross-correlations of pancolonic manometry data
    L Wiklendt
    St George Clinical School, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 25:e215-23. 2013
    ..Utilizing a cross-correlation technique, we have developed an automated analysis technique that can reliably differentiate the motor patterns of patients with slow transit constipation (STC) from those recorded in healthy controls...
  17. pmc The effect of luminal content and rate of occlusion on the interpretation of colonic manometry
    J W Arkwright
    CSIRO Materials Science and Engineering, Lindfield, NSW, Australia
    Neurogastroenterol Motil 25:e52-9. 2013
    ..This study tests the ability of manometry to record pressure signals in response to non-lumen-occluding changes in diameter, at different rates of wall movement and with content of different viscosities...
  18. doi request reprint The effect of sacral nerve stimulation on distal colonic motility in patients with faecal incontinence
    V Patton
    Department of Anorectal Physiology, St George Hospital, Sydney, Australia
    Br J Surg 100:959-68. 2013
    ..The aim of this study was to examine the effect of SNS on colonic propagating sequences (PSs) in patients with FI in whom urgency and incontinence was the predominant symptom...
  19. ncbi request reprint The proximal colonic motor response to rectal mechanical and chemical stimulation
    P A Bampton
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia 2217
    Am J Physiol Gastrointest Liver Physiol 282:G443-9. 2002
    ..Rectal distension inhibits all colonic motor activity...
  20. doi request reprint Pancolonic motor response to subsensory and suprasensory sacral nerve stimulation in patients with slow-transit constipation
    P G Dinning
    Department of Human Physiology, Flinders University, Bedford Park, South Australia
    Br J Surg 99:1002-10. 2012
    ..This study evaluated the colonic motor response to subsensory and suprasensory SNS in patients with slow-transit constipation...
  21. ncbi request reprint Validation of a semi-automated scintigraphic technique for detecting episodic, real-time colonic flow
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, New South Wales, Australia
    Neurogastroenterol Motil 18:547-55. 2006
    ....
  22. ncbi request reprint Removal of tonic nitrergic inhibition is a potent stimulus for human proximal colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 18:37-44. 2006
    ..We conclude that blockade of NO synthesis has a stimulatory effect on the frequency of proximal colonic PS. This suggests removal of tonic nitrergic inhibition of the colon might be a physiological stimulus for propagating activity...
  23. doi request reprint Optimal criteria for detecting bolus passage across the pharyngo-oesophageal segment during the normal swallow using intraluminal impedance recording
    M M Szczesniak
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:440-7. 2008
    ..Pharyngeal impedance provides an accurate, non-radiological indicator of bolus transit through the pharynx...
  24. doi request reprint High resolution colonic manometry--what have we learnt?--A review of the literature 2012
    P A Bampton
    Department of Gastroenterology, Flinders Medical Centre, Flinders University, Bedford Park, SA 5042, Australia
    Curr Gastroenterol Rep 15:328. 2013
    ..While this may suggest that no motor abnormalities exist in a proportion of such patients, the finding may also reflect technical constraints in our ability to detail colonic motility patterns...