Research Topics
Genomes and GenesSpecies | A DevineSummaryAffiliation: University of Western Australia Country: Australia Publications
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Detail Information
Publications
Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly womenAmanda Devine
Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Australia
Am J Clin Nutr 75:283-8. 2002..The relative importance of vitamin D metabolites in the regulation of gut calcium absorption has not been well studied in elderly women living in an environment with abundant sunlight...- Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal womenA Devine
Department of Medicine, University of Western Australia, Sir Charles Gairdner Hospital, Nedlands, Australia
Am J Clin Nutr 68:200-6. 1998..These results suggest that low zinc intake is associated with low IGF-I concentrations in healthy postmenopausal women and that the effects of zinc may be independent of protein intake... - Physical activity and calcium consumption are important determinants of lower limb bone mass in older womenAmanda Devine
School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia
J Bone Miner Res 19:1634-9. 2004..1% higher hip BMD than those who did not, supporting the concept that lifestyle factors play an important role in the maintenance of lower extremity bone mass in older women... - Prediction of incident osteoporotic fractures in elderly women using the free estradiol indexA Devine
School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, University of Western Australia, 4th Floor G Block, 6009, Nedlands, Western Australia, Australia
Osteoporos Int 16:216-21. 2005..These data confirm the importance of postmenopausal estrogen concentration in the pathogenesis of osteoporosis in elderly women... - Protein consumption is an important predictor of lower limb bone mass in elderly womenAmanda Devine
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Am J Clin Nutr 81:1423-8. 2005..The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes... - Klotho gene polymorphisms are associated with osteocalcin levels but not bone density of aged postmenopausal womenB H Mullin
Dept of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Western Australia, Australia
Calcif Tissue Int 77:145-51. 2005.... - Bone structural effects of variation in the TNFRSF1B gene encoding the tumor necrosis factor receptor 2B H Mullin
Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, 6009
Osteoporos Int 19:961-8. 2008..We analysed the TNFRSF1B gene from this region, which encodes the TNF receptor 2, in two large population-based cohorts. Our results suggest that variation in TNFRSF1B is associated with BMD... - A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulnessR L Prince
School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Australia
Bone 41:33-8. 2007..The data suggest that the estrogen effect on reducing spine fracture is at least in part due to an effect on bone structure and its measurement does not significantly improve fracture prediction... - Calcium-sensing receptor gene polymorphism A986S does not predict serum calcium level, bone mineral density, calcaneal ultrasound indices, or fracture rate in a large cohort of elderly womenJ Bollerslev
School of Medicine and Pharmacology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
Calcif Tissue Int 74:12-7. 2004..It is questioned whether the polymorphism has any clinical significance for postmenopausal osteoporosis... - LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian womenJ Bollerslev
School of Medicine and Pharmacology, University of Western Australia, Nedlands
Bone 36:599-606. 2005..67 [1.02-2.78], P = 0.045), indicating factors other than bone mass are of importance for bone strength. In conclusion, genetic variation in LRP5 seems to be of importance for regulation of bone mass and osteoporotic fractures... - Association of an aromatase TTTA repeat polymorphism with circulating estrogen, bone structure, and biochemistry in older womenI M Dick
School of Medicine and Pharmacology, Univ of Western Australia, 4th Floor G Block, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia
Am J Physiol Endocrinol Metab 288:E989-95. 2005.... - The clinical utility of measured kyphosis as a predictor of the presence of vertebral deformitiesR L Prince
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
Osteoporos Int 18:621-7. 2007.... - The effects of homocysteine and MTHFR genotype on hip bone loss and fracture risk in elderly womenK Zhu
School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia
Osteoporos Int 20:1183-91. 2009..In our 5-year cohort study with 1,213 women aged 70-85 years, high homocysteine is associated with greater hip bone loss but not fracture risk. The effect of MTHFR genotype on bone density and fracture is weak... - Bone mass effects of a BMP4 gene polymorphism in postmenopausal womenL Ramesh Babu
School of Medicine and Pharmacology, University of Western Australia, Nedlands, WA, Australia
Bone 36:555-61. 2005..We conclude that a polymorphism found in the BMP4 gene, affecting amino acid sequence, is associated with hip bone density in postmenopausal women, presumably via regulation of anabolic effects on the skeleton... - Effects of endogenous estrogen on renal calcium and phosphate handling in elderly womenI M Dick
School of Medicine and Pharmacology, Univ of Western Australia, 4th Floor G Block, Sir Charles Gairdner Hospital, Nedlands, WA, Australia 6009
Am J Physiol Endocrinol Metab 288:E430-5. 2005.... - The effects of high potassium consumption on bone mineral density in a prospective cohort study of elderly postmenopausal womenK Zhu
Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
Osteoporos Int 20:335-40. 2009.... - Adequacy and change in nutrient and food intakes with aging in a seven-year cohort study in elderly womenK Zhu
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
J Nutr Health Aging 14:723-9. 2010..The aims of this study were to investigate the changes in nutrient and dietary intakes that occurred with aging in a seven-year longitudinal study of elderly Australian women and to evaluate the adequacy of their dietary intakes... - The T869C TGF beta polymorphism is associated with fracture, bone mineral density, and calcaneal quantitative ultrasound in elderly womenI M Dick
Department of Medicine, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, WA, Australia
Bone 33:335-41. 2003..These findings are of potential clinical usefulness, as the TGF beta T869C genotype could be used, in conjunction with other genetic and clinical information, to determine an individual's risk of osteoporosis... - Randomized controlled trial of the effects of calcium with or without vitamin D on bone structure and bone-related chemistry in elderly women with vitamin D insufficiencyKun Zhu
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
J Bone Miner Res 23:1343-8. 2008..Vitamin D supplementation adds no extra short-term skeletal benefit to calcium citrate supplementation even in women with vitamin D insufficiency... - Apolipoprotein E4 is associated with reduced calcaneal quantitative ultrasound measurements and bone mineral density in elderly womenI M Dick
Department of Medicine, University of Western Australia, Perth, WA, Australia
Bone 31:497-502. 2002.... - Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly womenRichard L Prince
School of Medicine and Pharmacology, University of Western Australia, Australia
Arch Intern Med 166:869-75. 2006..We have examined whether calcium supplementation decreases clinical fracture risk in elderly women and its mechanism of action... - A randomized controlled trial of the effects of vitamin D on muscle strength and mobility in older women with vitamin D insufficiencyKun Zhu
School of Medicine and Pharmacology, University of Western Australia, Perth, Australia
J Am Geriatr Soc 58:2063-8. 2010..To evaluate the effects of vitamin D treatment on muscle strength and mobility in older women with vitamin D insufficiency... - Effects of ergocalciferol added to calcium on the risk of falls in elderly high-risk womenRichard L Prince
School of Medicine and Pharmacology, Univerity of Western Australia, Perth, Australia
Arch Intern Med 168:103-8. 2008..We evaluated the effect of ergocalciferol and calcium citrate supplementation compared with calcium alone on the risk of falls in older women at high risk of falling... - Chocolate consumption and bone density in older womenJonathan M Hodgson
Royal Perth Hospital Unit, the University of Western Australia School of Medicine and Pharmacology, Perth, Australia
Am J Clin Nutr 87:175-80. 2008..Nutrition is important for the development and maintenance of bone structure and for the prevention of osteoporosis and fracture. The relation of chocolate intake with bone has yet to be investigated... - Effects of calcium and vitamin D supplementation on hip bone mineral density and calcium-related analytes in elderly ambulatory Australian women: a five-year randomized controlled trialKun Zhu
School of Medicine and Pharmacology, University of Western Australia, Crawley, Australia
J Clin Endocrinol Metab 93:743-9. 2008..Effects of long-term calcium, with or without vitamin D, on hip bone mineral density (BMD) and bone turnover in sunny climates have not been reported... - Tea intake is inversely related to blood pressure in older womenJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, and the Western Australian Institute for Medical Research WAIMR, Western Australia, Australia
J Nutr 133:2883-6. 2003..The observed associations for both tea intake and 4-O-methylgallic acid are consistent with the hypothesis that long-term regular ingestion of tea may have a favorable effect on blood pressure in older women... - Drinking tea is associated with lower plasma total homocysteine in older womenJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, PO Box X2213, Perth, WA 6001, Australia
Asia Pac J Clin Nutr 15:253-8. 2006..The observed lower tHcy in women with higher tea intake is consistent in direction and magnitude with previous epidemiological studies, but any mechanisms remain unclear... - Fear of falling in older women: a longitudinal study of incidence, persistence, and predictorsNicole Austin
School of Medicine and Pharmacology, Sir Charles Gairdner Hospital Unit, University of Western Australia, Perth, Western Australia, Australia
J Am Geriatr Soc 55:1598-603. 2007..To determine longitudinal predictors of incident and persistent fear of falling (FOF) in older women... - Association of back pain frequency with mortality, coronary heart events, mobility, and quality of life in elderly womenKun Zhu
Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
Spine (Phila Pa 1976) 32:2012-8. 2007..A 5-year observational cohort design using data from a randomized controlled trial of calcium intervention... - Phenolic acid metabolites as biomarkers for tea- and coffee-derived polyphenol exposure in human subjectsJonathan M Hodgson
University of Western Australia School of Medicine and Pharmacology, Royal Perth Hospital, Perth, Western Australia, Australia
Br J Nutr 91:301-6. 2004.... - Do sleep problems or urinary incontinence predict falls in elderly women?Joy S H Teo
School of Physiotherapy, Curtin University of Technology, Perth, Western Australia
Aust J Physiother 52:19-24. 2006..As urge incontinence and abnormal daytime sleepiness were independently associated with an increased falls risk, effective management of these problems may reduce the risk of falling in older women... - Recreational physical activity levels in healthy older women: the importance of fear of fallingDavid G Bruce
Department of Medicine, University of Western Australia, Perth, Australia
J Am Geriatr Soc 50:84-9. 2002..Fear of falling is an important psychological barrier that may need to be overcome in programs attempting to improve activity levels in older women... - A 5-year cohort study of the effects of high protein intake on lean mass and BMC in elderly postmenopausal womenXingqiong Meng
Curtin Health Innovation Research Institute and School of Public Health, Curtin University of Technology, Perth, Western Australia, Australia
J Bone Miner Res 24:1827-34. 2009..This study shows that high protein intake is associated with long-term beneficial effects on muscle mass and size and bone mass in elderly women. The protein effect on bone may be partly mediated by its effects on muscle... - Geometric indices of bone strength are associated with physical activity and dietary calcium intake in healthy older womenMichelle K Nurzenski
School of Physiotherapy, Curtin University of Technology, and Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Western Australia, Australia
J Bone Miner Res 22:416-24. 2007..4-4.4% higher femoral bone strength in axial compression and 1.7-5.2% in bending than those achieving low levels, indicating that lifestyle factors influence bone strength in the proximal femur... - Prevalence of lower extremity pain and its association with functionality and quality of life in elderly women in AustraliaJuan Chen
School of Medicine and Pharmacology, University of Western Australia, Perth, West Australia, Australia
J Rheumatol 30:2689-93. 2003..In view of the availability of effective interventions to reduce joint pain, more aggressive intervention in the most disabled is indicated... - Expression of the HFE hemochromatosis gene in a community-based population of elderly womenEnrico Rossi
Department of Clinical Biochemistry, PathCentre Western Australian Centre for Pathology and Medical Research, Nedlands, Western Australia, Australia
J Gastroenterol Hepatol 19:1150-4. 2004..Recent studies suggest that the clinical penetrance of associated hereditary hemochromatosis, defined as either the C282Y homozygote or compound heterozygote HFE genotype status, is much lower than previously thought... - Tea drinking is associated with benefits on bone density in older womenAmanda Devine
Nutrition Program, School of Exercise, Biomedical and Health Science, Edith Cowan University, 100 Joondalup Drive, Joondalup WA 6027 Australia
Am J Clin Nutr 86:1243-7. 2007..Impaired hip structure assessed by dual-energy X-ray absorptiometry (DXA) areal bone mineral density (aBMD) is an independent predictor for osteoporotic hip fracture. Some studies suggest that tea intake may protect against bone loss... - Gonadotropins and cognition in older womenMark A Rodrigues
Centre of Excellence for Alzheimer s Disease Research and Care, Hollywood Private Hospital, School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Australia
J Alzheimers Dis 13:267-74. 2008..Taken together, the findings have important implications for the development of possible preventive strategies for dementia...