Shane Darke

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint Circumstances and toxicology of sudden or unnatural deaths involving alprazolam
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia Electronic address
    Drug Alcohol Depend 138:61-6. 2014
  2. doi request reprint Toxicology, circumstances and pathology of deaths from acute alcohol toxicity
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia New South Wales Forensic and Analytical Science Service, Sydney West Local Health District, NSW, Australia Electronic address
    J Forensic Leg Med 20:1122-5. 2013
  3. ncbi request reprint Childhood physical abuse, non-suicidal self-harm and attempted suicide amongst regular injecting drug users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia Electronic address
    Drug Alcohol Depend 133:420-6. 2013
  4. doi request reprint Characteristics, circumstances and toxicology of sudden or unnatural deaths involving very high-range alcohol concentrations
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Randwick, NSW 2052, Australia
    Addiction 108:1411-7. 2013
  5. doi request reprint Pathways to heroin dependence: time to re-appraise self-medication
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Addiction 108:659-67. 2013
  6. ncbi request reprint Age-related patterns of drug use initiation among polydrug using regular psychostimulant users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:784-9. 2012
  7. ncbi request reprint Toxicology and characteristics of deaths involving zolpidem in New South Wales, Australia 2001-2010
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Sydney, Australia
    J Forensic Sci 57:1259-62. 2012
  8. doi request reprint Comparative patterns of cognitive performance amongst opioid maintenance patients, abstinent opioid users and non-opioid users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia
    Drug Alcohol Depend 126:309-15. 2012
  9. doi request reprint Self-harm and attempted suicide among therapeutic community admissions
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:523-8. 2012
  10. doi request reprint Retention, early dropout and treatment completion among therapeutic community admissions
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:64-71. 2012

Detail Information

Publications92

  1. ncbi request reprint Circumstances and toxicology of sudden or unnatural deaths involving alprazolam
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia Electronic address
    Drug Alcohol Depend 138:61-6. 2014
    ..This paper reported on alprazolam positive cases of sudden or unnatural deaths presenting to the New South Wales Department of Forensic Medicine (DOFM), 1/1/1997-31/12/2012...
  2. doi request reprint Toxicology, circumstances and pathology of deaths from acute alcohol toxicity
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia New South Wales Forensic and Analytical Science Service, Sydney West Local Health District, NSW, Australia Electronic address
    J Forensic Leg Med 20:1122-5. 2013
    ..Cardiac disease was noted in 75.9% of cases and hepatic disease in 91.6%. The only alcohol-related organic brain syndrome pathology identified at autopsy was vermal cerebellar degeneration. ..
  3. ncbi request reprint Childhood physical abuse, non-suicidal self-harm and attempted suicide amongst regular injecting drug users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia Electronic address
    Drug Alcohol Depend 133:420-6. 2013
    ..Childhood physical abuse (CPA), non-suicidal self-harm and attempted suicide are all highly prevalent amongst injecting drug users (IDU). This paper reported on the association of CPA with self-harm and attempted suicide...
  4. doi request reprint Characteristics, circumstances and toxicology of sudden or unnatural deaths involving very high-range alcohol concentrations
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Randwick, NSW 2052, Australia
    Addiction 108:1411-7. 2013
    ..To characterize sudden or unnatural deaths with very high-range blood alcohol concentrations (BACs) presenting to the Department of Forensic Medicine (DOFM) in Sydney between 1 January 1997 and 31 December 2011...
  5. doi request reprint Pathways to heroin dependence: time to re-appraise self-medication
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Addiction 108:659-67. 2013
    ..In contrast, the postulate of drug specificity appears less supported by the polydrug use patterns typical of heroin users, and does not appear to be a necessary corollary of the model...
  6. ncbi request reprint Age-related patterns of drug use initiation among polydrug using regular psychostimulant users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:784-9. 2012
    ..To determine age-related patterns of drug use initiation, drug sequencing and treatment entry among regular psychostimulant users...
  7. ncbi request reprint Toxicology and characteristics of deaths involving zolpidem in New South Wales, Australia 2001-2010
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Sydney, Australia
    J Forensic Sci 57:1259-62. 2012
    ..2%), benzodiazepines (35.2%), opioids (26.4%), and alcohol (39.6%). In summary, zolpidem was a factor contributing to death in a large proportion of cases, predominately involving drug toxicity and suicide...
  8. doi request reprint Comparative patterns of cognitive performance amongst opioid maintenance patients, abstinent opioid users and non-opioid users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia
    Drug Alcohol Depend 126:309-15. 2012
    ..To compare the cognitive performances of maintenance patients (MAIN), abstinent ex-users (ABST) and healthy non-heroin using controls (CON)...
  9. doi request reprint Self-harm and attempted suicide among therapeutic community admissions
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:523-8. 2012
    ..The study aimed to determine the histories of self-harm and attempted suicide among therapeutic community entrants by primary presenting substance problem, and to determine predictors of these behaviours...
  10. doi request reprint Retention, early dropout and treatment completion among therapeutic community admissions
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 31:64-71. 2012
    ..The study aimed to ascertain the association between baseline client characteristics, drug use and psychopathology on length of stay, treatment completion and early separation in drug free therapeutic communities...
  11. doi request reprint Toxicology and circumstances of death of homicide victims in New South Wales, Australia 1996-2005
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    J Forensic Sci 53:447-51. 2008
    ..Psychoactive substances appear to substantially increase the risk of homicide, although there are important differences between drug classes in the circumstances of such incidents...
  12. doi request reprint From the can to the coffin: deaths among recently released prisoners
    Shane Darke
    Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 103:256-7. 2008
  13. ncbi request reprint Comparative toxicology of fatal heroin overdose cases and morphine positive homicide victims
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Addiction 102:1793-7. 2007
    ..To compare the blood toxicology of heroin overdose cases and morphine positive homicide victims...
  14. ncbi request reprint Borderline personality disorder and persistently elevated levels of risk in 36-month outcomes for the treatment of heroin dependence
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 102:1140-6. 2007
    ..Aims: To determine the effects of borderline personality disorder (BPD) on 36-month outcomes for the treatment of heroin dependence...
  15. ncbi request reprint The Australian Treatment Outcome Study (ATOS): what have we learnt about treatment for heroin dependence?
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
    Drug Alcohol Rev 26:49-54. 2007
    ..It is argued that treatment for heroin dependence is money well spent, and leads to clear and sustained benefits to both heroin users and society...
  16. ncbi request reprint Patterns of sustained heroin abstinence amongst long-term, dependent heroin users: 36 months findings from the Australian Treatment Outcome Study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, 2052, Australia
    Addict Behav 32:1897-906. 2007
    ..To determine patterns of past month, 12 month and sustained 36 month heroin abstinence...
  17. doi request reprint Attempted suicide, self-harm, and violent victimization among regular illicit drug users
    Shane Darke
    National and Alcohol Research Centre, University of New South Wales, Australia
    Suicide Life Threat Behav 40:587-96. 2010
    ..0yrs) was significantly younger than that of nonsuicidal self-harm and initial suicide attempt. Screening for all forms of violence appears warranted when determining suicide risk for this population...
  18. ncbi request reprint Patterns and correlates of attempted suicide by heroin users over a 3-year period: findings from the Australian treatment outcome study
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 87:146-52. 2007
    ..Given the strong predictive value of suicidal ideation and previous attempts, regular brief screening would appear warranted to identify those at greatest risk...
  19. ncbi request reprint Reductions in heroin use are not associated with increases in other drug use: 2-year findings from the Australian Treatment Outcome Study
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Depend 84:201-5. 2006
    ..To determine whether reductions in frequency of heroin use were associated with reductions in the use of other drugs over a 24-month period...
  20. ncbi request reprint Non-fatal heroin overdose, treatment exposure and client characteristics: findings from the Australian treatment outcome study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 24:425-32. 2005
    ..62). Other independent predictors of overdose over follow-up were more extensive polydrug use (OR 1.40), and having overdosed in the year preceding the study (OR 7.87)...
  21. doi request reprint Truth is not always found in the laboratory
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Addiction 103:1066-7; discussion 1067-8. 2008
  22. ncbi request reprint Patterns of major depression and drug-related problems amongst heroin users across 36 months
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia
    Psychiatry Res 166:7-14. 2009
    ..It was concluded that, with the exception of depression, the prognosis of depressed heroin users is not worse than that of non-depressed users...
  23. ncbi request reprint Toxicology and circumstances of completed suicide by means other than overdose
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    J Forensic Sci 54:490-4. 2009
    ..Pharmaceuticals were more common where a previous attempt was noted. Licit and illicit substances are strongly associated with suicide, even when the method does not involve drug overdose...
  24. doi request reprint Rates and correlates of mortality amongst heroin users: findings from the Australian Treatment Outcome Study (ATOS), 2001-2009
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    Drug Alcohol Depend 115:190-5. 2011
    ..Mortality rates were lower than those seen outside Australasia. Screening for overdose by those treating heroin users would be appropriate, and may contribute to reductions in overall mortality...
  25. doi request reprint Cardiovascular disease risk factors and symptoms among regular psychostimulant users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    Drug Alcohol Rev 29:371-7. 2010
    ..The aim of this study is to determine the prevalence of risk factors and possible symptoms of cardiovascular disease among regular psychostimulant users...
  26. doi request reprint Benzodiazepine use among heroin users: baseline use, current use and clinical outcome
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 29:250-5. 2010
    ..Benzodiazepine use is associated with elevated levels of harm. The current study aimed to ascertain the long-term nature of the relationship between benzodiazepine use and clinical profile among heroin users...
  27. doi request reprint The toxicology of homicide offenders and victims: A review
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Drug Alcohol Rev 29:202-15. 2010
    ..The toxicology of homicide offenders and victims, and homicide as a cause of death among psychoactive substance users...
  28. ncbi request reprint Comparative toxicology of intentional and accidental heroin overdose
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    J Forensic Sci 55:1015-8. 2010
    ..05), and the presence of cocaine (p < 0.05). The current data are consistent with the view that suicide forms a small, but distinct, category of heroin overdose cases, rather than overdose being a parasuicidal phenomenon per se...
  29. doi request reprint A reduction in blood morphine concentrations amongst heroin overdose fatalities associated with a sustained reduction in street heroin purity
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Forensic Sci Int 198:118-20. 2010
    ..07). In determining toxic and lethal morphine concentrations, the fact that the toxicology of overdose is responsive to changes in the opioid street market needs to be borne in mind...
  30. doi request reprint Comparative rates of violent crime among regular methamphetamine and opioid users: offending and victimization
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 105:916-9. 2010
    ..To determine the comparative levels of violent offending and victimization among regular methamphetamine and heroin users...
  31. doi request reprint The comparative toxicology and major organ pathology of fatal methadone and heroin toxicity cases
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    Drug Alcohol Depend 106:1-6. 2010
    ....
  32. doi request reprint The ageing heroin user: career length, clinical profile and outcomes across 36 months
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 28:243-9. 2009
    ..The study examined the relationships between length of career (LOC), clinical presentation and outcomes across 36 months among a cohort of 615 heroin users...
  33. doi request reprint Drugs and violent death: comparative toxicology of homicide and non-substance toxicity suicide victims
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Addiction 104:1000-5. 2009
    ..To determine the comparative toxicology of death by homicide and suicide by means other than substance toxicity...
  34. pmc Patterns of nonfatal heroin overdose over a 3-year period: findings from the Australian treatment outcome study
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    J Urban Health 84:283-91. 2007
    ..While overdose rates declined after extensive treatment, substantial proportions continued to overdose in each year, and this was strongly associated with overdose history...
  35. pmc Attempted suicide among injecting and noninjecting cocaine users in Sydney, Australia
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, New South Wales, Australia
    J Urban Health 81:505-15. 2004
    ..Those treating cocaine users for drug dependence need to be aware of the salience of suicide as a problem, among injectors in particular...
  36. ncbi request reprint Non-injecting routes of administration among entrants to three treatment modalities for heroin dependence
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 23:177-83. 2004
    ..While this group is younger, and has substantially reduced risk of overdose and blood borne virus transmission, the physical and psychological health of non-injectors mirrors that of injectors...
  37. ncbi request reprint Cocaine-related fatalities in New South Wales, Australia 1993-2002
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 77:107-14. 2005
    ..To ascertain the demographic characteristics, circumstances of death, toxicological results, and major autopsy findings of cocaine-related fatalities...
  38. ncbi request reprint Borderline personality disorder, antisocial personality disorder and risk-taking among heroin users: findings from the Australian Treatment Outcome Study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, P O Box 1, New South Wales 2052, Australia
    Drug Alcohol Depend 74:77-83. 2004
    ..To determine the relationship between borderline personality disorder (BPD), antisocial personality disorder (ASPD) and harm among current heroin users...
  39. ncbi request reprint Drug driving among injecting drug users in Sydney, Australia: prevalence, risk factors and risk perceptions
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 99:175-85. 2004
    ..To examine the prevalence of drug driving, the prevalence of drug-related motor vehicle accidents, risk perceptions of drug driving and factors associated with drug driving among injecting drug users (IDU)...
  40. ncbi request reprint Factors associated with 12 months continuous heroin abstinence: findings from the Australian Treatment Outcome Study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    J Subst Abuse Treat 28:255-63. 2005
    ..To determine the role of treatment and client characteristics associated with the achievement of continuous heroin abstinence...
  41. ncbi request reprint Health service utilization and benzodiazepine use among heroin users: findings from the Australian Treatment Outcome Study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 98:1129-35. 2003
    ..To determine levels of health service utilization among heroin users, the types of prescription drugs obtained by heroin users and the contribution of benzodiazepine use in health service utilization and prescribed drug use...
  42. ncbi request reprint The relationship of conduct disorder to attempted suicide and drug use history among methadone maintenance patients
    Shane Darke
    National Drug and Alcohol Research Center, University of New South Wales, Randwick, Australia
    Drug Alcohol Rev 22:21-5. 2003
    ..The current study indicates that a history of CD increases the risk of attempted suicide over and above the higher risks associated with injecting drug use per se...
  43. ncbi request reprint Cocaine use in New South Wales, Australia, 1996-2000: 5 year monitoring of trends in price, purity, availability and use from the illicit drug reporting system
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia
    Drug Alcohol Depend 67:81-8. 2002
    ..The regular and formal monitoring of illicit drug trends enabled substantial changes in the cocaine market in Sydney to be detected, and the information to be fed back to the health and law enforcement sectors...
  44. ncbi request reprint The impact of borderline personality disorder on 12-month outcomes for the treatment of heroin dependence
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 100:1121-30. 2005
    ..To determine the effects of borderline personality disorder (BPD) on 12-month treatment retention and outcomes for the treatment of heroin dependence...
  45. ncbi request reprint Twelve-month outcomes for heroin dependence treatments: does route of administration matter?
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 24:165-71. 2005
    ..It is concluded that, among those presenting for treatment, route of administration is not an indicator of likely outcome...
  46. ncbi request reprint The characteristics of heroin users entering treatment: findings from the Australian treatment outcome study (ATOS)
    Joanne Ross
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 24:411-8. 2005
    ..Striking similarities were noted between the non-treatment and treatment groups in length of heroin use career, drug use and treatment histories...
  47. ncbi request reprint Attempted suicide among entrants to three treatment modalities for heroin dependence in the Australian Treatment Outcome Study (ATOS): prevalence and risk factors
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 73:1-10. 2004
    ....
  48. ncbi request reprint Post-traumatic stress disorder among people with heroin dependence in the Australian treatment outcome study (ATOS): prevalence and correlates
    Katherine L Mills
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 77:243-9. 2005
    ..It is concluded that PTSD is highly prevalent among individuals with heroin dependence, presenting a significant challenge to treatment providers...
  49. ncbi request reprint One year outcomes for heroin dependence: findings from the Australian Treatment Outcome Study (ATOS)
    Maree Teesson
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Drug Alcohol Depend 83:174-80. 2006
    ..To determine 1 year outcomes for drug use, criminality, psychopathology and injection-related health problems in those entering treatment for heroin dependence in Australia...
  50. doi request reprint Methamphetamine-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology
    Sharlene Kaye
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 103:1353-60. 2008
    ..To examine the demographic characteristics, circumstances of death, toxicological results and major organ pathology of methamphetamine-related deaths in Australia...
  51. ncbi request reprint Young people with heroin dependence: findings from the Australian Treatment Outcome Study (ATOS)
    Katherine L Mills
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    J Subst Abuse Treat 27:67-73. 2004
    ..These findings suggest that there is a limited window of opportunity in which early interventions may be applied before young heroin users progress to problematic use...
  52. ncbi request reprint Reliability of self-reported trauma exposure among people with heroin dependence: a longitudinal investigation
    Katherine Mills
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    J Trauma Stress 20:313-23. 2007
    ..These findings suggest that dependent heroin users are moderately reliable in their reports of trauma exposure, and their reports of trauma exposure are as reliable as those of nonsubstance use disordered samples...
  53. ncbi request reprint The effect of baseline cocaine use on treatment outcomes for heroin dependence over 24 months: findings from the Australian Treatment Outcome Study
    Anna Williamson
    National Drug and Alcohol Research Centre, University of New South Wales, New South Wales 2052, Australia
    J Subst Abuse Treat 33:287-93. 2007
    ..The aim of this study was to determine the effects of baseline cocaine use on treatment outcomes for heroin dependence over a 24-month period...
  54. ncbi request reprint Outcomes after detoxification for heroin dependence: findings from the Australian Treatment Outcome Study (ATOS)
    Maree Teesson
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 25:241-7. 2006
    ..Psychopathology showed less change. Detoxification may, in some part, function as a gateway to further treatment and those entering DTX showed modest but significant improvements across drug use and crime at 3 months...
  55. ncbi request reprint Changes in the use of medical services and prescription drugs among heroin users over two years
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Drug Alcohol Rev 26:153-9. 2007
    ..While ATOS participants continued to be frequent users of health services, the cohort reported reduced levels of drug-seeking and risk commensurate with their reductions in drug use...
  56. ncbi request reprint The effect of persistence of cocaine use on 12-month outcomes for the treatment of heroin dependence
    Anna Williamson
    National Drug and Alcohol Research Centre, University of New South Wales, Randwick Campus, 22 32 King St, Randwick, NSW 2052, Australia
    Drug Alcohol Depend 81:293-300. 2006
    ..To determine the effects of cocaine use across the study period on outcomes of treatment for heroin dependence 12 months post-treatment entry...
  57. ncbi request reprint The impact of treatment on 3 years' outcome for heroin dependence: findings from the Australian Treatment Outcome Study (ATOS)
    Maree Teesson
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 103:80-8. 2008
    ..To examine the impact of treatment for heroin dependence on drug use, injection-related risk-taking, health problems, criminality and general physical and mental health over 3 years among heroin-dependent Australians...
  58. doi request reprint Changes and predictors of change in the physical health status of heroin users over 24 months
    Anna Williamson
    School of Public Health and Community Medicine, University of New South Wales, NSW, Australia
    Addiction 104:465-70. 2009
    ..i) To describe the course of physical health among the ATOS cohort over 24 months; and (ii) to examine the effects of treatment, drug use patterns and social and psychological factors on health status over 24 months...
  59. doi request reprint Methylenedioxymethamphetamine (MDMA)-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology
    Sharlene Kaye
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Drug Alcohol Depend 104:254-61. 2009
    ..To examine the demographic characteristics, circumstances, toxicology and major organ pathology of MDMA-related deaths in Australia...
  60. ncbi request reprint The association between cocaine use and short-term outcomes for the treatment of heroin dependence: findings from the Australian Treatment Outcome Study (ATOS)
    Anna Williamson
    National Drug and Alcohol Research Centre, University of NSW, Australia
    Drug Alcohol Rev 25:141-8. 2006
    ..It appears that cocaine use has a strong negative effect on treatment outcome over and above that caused by polydrug use generally...
  61. doi request reprint Toxicology and characteristics of fatal oxycodone toxicity cases in New South Wales, Australia 1999-2008
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    J Forensic Sci 56:690-3. 2011
    ..6%), other opioids (54.3%), antidepressants (41.4%), and alcohol (32.9%). Preexisting systemic disease was common: cardiovascular (64.2%), pulmonary (49.3%), hepatic (66.7%), and renal (43.9%)...
  62. pmc Investigating the co-occurrence of self-mutilation and suicide attempts among opioid-dependent individuals
    Elizabeth Maloney
    National Drug and Alcohol Research Centre, University of New South Wales 2052, Sydney, Australia
    Suicide Life Threat Behav 40:50-62. 2010
    ..Not only is self-mutilation a clinically significant problem, but when combined with a history of attempted suicide, the psychological dysfunction observed is markedly high...
  63. ncbi request reprint The injection of methadone and benzodiazepines among Sydney injecting drug users 1996-2000: 5-year monitoring of trends from the Illicit Drug Reporting System
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 21:27-32. 2002
    ..Given the substantial harms associated with these practices, continued monitoring of their prevalence is warranted...
  64. ncbi request reprint Attempted suicide among heroin users: 12-month outcomes from the Australian Treatment Outcome Study (ATOS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 78:177-86. 2005
    ....
  65. ncbi request reprint Hair morphine concentrations of fatal heroin overdose cases and living heroin users
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Austrlia
    Addiction 97:977-84. 2002
    ..To compare heroin and other opiate use of heroin overdose fatalities, current street heroin users and drug-free therapeutic community clients...
  66. pmc Are non-fatal opioid overdoses misclassified suicide attempts? Comparing the associated correlates
    Elizabeth Maloney
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia
    Addict Behav 34:723-9. 2009
    ..Additionally, if both behaviours are reported a thorough assessment of underlying comorbid problems should be initiated by treatment services...
  67. ncbi request reprint Depression among entrants to treatment for heroin dependence in the Australian Treatment Outcome Study (ATOS): prevalence, correlates and treatment seeking
    Maree Teesson
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Drug Alcohol Depend 78:309-15. 2005
    ..To determine the rate of current major depressive disorder (MDD) among entrants to treatment for heroin dependence in three treatment modalities and a non-treatment comparison group; and to ascertain factors associated with depression...
  68. ncbi request reprint The prevalence and correlates of gamma-hydroxybutyrate (GHB) overdose among Australian users
    Louisa Degenhardt
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSE 2052, Australia
    Addiction 98:199-204. 2003
    ..The aim of this study was to examine the correlates, context and risk perceptions regarding gamma-hydroxybutyrate (GHB) overdose among a sample of recreational GHB users in Australia...
  69. ncbi request reprint Non-fatal cocaine overdose among injecting and non-injecting cocaine users in Sydney, Australia
    Sharlene Kaye
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 99:1315-22. 2004
    ..To investigate the frequency of non-fatal cocaine overdose, and responses to overdoses, among injecting and non-injecting cocaine users...
  70. pmc Impulsivity and borderline personality as risk factors for suicide attempts among opioid-dependent individuals
    Elizabeth Maloney
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia
    Psychiatry Res 169:16-21. 2009
    ..This research also highlights the importance of assessing impulsivity, in both clinical settings and research, particularly among those with a history of suicidal behaviour...
  71. doi request reprint Major physical and psychological harms of methamphetamine use
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
    Drug Alcohol Rev 27:253-62. 2008
    ..The major physical and psychological health effects of methamphetamine use, and the factors associated with such harms...
  72. ncbi request reprint Decreased heroin availability in Sydney in early 2001
    Carolyn Day
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Addiction 98:93-5. 2003
    ..To examine the veracity of reports of a substantial decrease in the availability of heroin in Sydney in January 2001...
  73. ncbi request reprint Depression among heroin users: 12-Month outcomes from the Australian Treatment Outcome Study (ATOS)
    Alys Havard
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia
    J Subst Abuse Treat 30:355-62. 2006
    ..Although caution in interpreting these relationships is advised given the potential for confounding by client characteristics, the findings of this study illustrate the need to consider depression in the treatment of heroin dependence...
  74. ncbi request reprint Morbidity associated with non-fatal heroin overdose
    Matthew Warner-Smith
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Addiction 97:963-7. 2002
    ..To estimate the range and severity of heroin overdose related morbidity...
  75. ncbi request reprint Comparative cardiac pathology among deaths due to cocaine toxicity, opioid toxicity and non-drug-related causes
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 101:1771-7. 2006
    ..To compare cardiac and cerebrovascular pathology among deaths due to cocaine toxicity, deaths due to opioid toxicity and deaths from hanging that were toxicologically negative for cocaine/opioids...
  76. ncbi request reprint Heroin use in New South Wales, Australia, 1996-2000: 5 year monitoring of trends in price, purity, availability and use from the Illicit Drug Reporting System (IDRS)
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Addiction 97:179-86. 2002
    ..To document trends in the price, purity, availability and use of heroin in New South Wales detected by the Illicit Drug Reporting System (IDRS) between 1996 and 2000, and to demonstrate the utility of the IDRS in identifying such trends...
  77. ncbi request reprint Suicide among heroin users: rates, risk factors and methods
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 97:1383-94. 2002
    ..It is concluded that suicide is a major problem that treatment agencies face, and which requires targeted intervention if the rates of suicide among this group are to decline...
  78. ncbi request reprint GHB use among Australians: characteristics, use patterns and associated harm
    Louisa Degenhardt
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW 2052, Australia
    Drug Alcohol Depend 67:89-94. 2002
    ..The high rate of problems reported by a group with limited use of this drug suggests that in a context of polydrug use, GHB use is associated with significant risks to users...
  79. ncbi request reprint Systemic disease among cases of fatal opioid toxicity
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
    Addiction 101:1299-305. 2006
    ..To determine levels of systemic disease among cases of death due to opioid toxicity...
  80. ncbi request reprint The monitoring of drug trends in Australia
    Fiona Shand
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 22:61-72. 2003
    ....
  81. ncbi request reprint A review of drug use and driving: epidemiology, impairment, risk factors and risk perceptions
    Erin Kelly
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Drug Alcohol Rev 23:319-44. 2004
    ..g. cannabis) seen as producing less impairment than others (e.g. alcohol). It is concluded that drug driving is a significant problem, both in terms of a general public health issue and as a specific concern for drug users...
  82. pmc Heroin overdose: research and evidence-based intervention
    Shane Darke
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    J Urban Health 80:189-200. 2003
    ..Responses by heroin users at overdoses are also examined. Potential interventions to reduce the rate of overdose and overdose-related morbidity are examined in light of the emerging data in this field...
  83. ncbi request reprint Methamphetamine and cardiovascular pathology: a review of the evidence
    Sharlene Kaye
    National Drug and Alcohol Research Centre, University of New South Wales, Australia
    Addiction 102:1204-11. 2007
    ..To examine the literature pertaining to the cardiovascular effects of methamphetamine and discuss the implications for methamphetamine users...
  84. ncbi request reprint The impact of post-traumatic stress disorder on treatment outcomes for heroin dependence
    Katherine L Mills
    National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia
    Addiction 102:447-54. 2007
    ..To examine the impact of post-traumatic stress disorder (PTSD) on 2-year treatment outcomes for heroin dependence...
  85. ncbi request reprint The costs and outcomes of treatment for opioid dependence associated with posttraumatic stress disorder
    Katherine L Mills
    National Drug and Alcohol Research Centre of the University of New South Wales, Randwick, N S W 2052, Australia
    Psychiatr Serv 56:940-5. 2005
    ..This study examined the costs and outcomes of treatment for opiate dependence associated with posttraumatic stress disorder (PTSD)...
  86. ncbi request reprint Injecting and non-injecting cocaine use in Sydney, Australia: physical and psychological morbidity
    Sharlene Kaye
    National Drug and Alcohol Research Centre University of New South Wales, Australia
    Drug Alcohol Rev 23:391-8. 2004
    ..Harm reduction initiatives should be targeted towards all cocaine users, not just those who seek treatment for dependence or present with acute medical complications...
  87. ncbi request reprint Suicidal behaviour and associated risk factors among opioid-dependent individuals: a case-control study
    Elizabeth Maloney
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Addiction 102:1933-41. 2007
    ..To examine suicidal behaviour and the associated risk factors among opioid-dependent cases and non-opioid-dependent controls...
  88. ncbi request reprint Prevalence and correlates of intravenous methadone syrup administration in Adelaide, Australia
    Rachel Humeniuk
    Drug and Alcohol Services Council, Parkside, South Australia, Australia
    Addiction 98:413-8. 2003
    ..The aims of this study were to determine the prevalence of methadone syrup injecting in Adelaide, South Australia and to characterize methadone injectors, including their heroin use and risk behaviours associated with heroin overdose...
  89. ncbi request reprint Heroin supply and health: new perspectives
    Shane Darke
    Addiction 99:275. 2004
  90. ncbi request reprint Adapting the Illicit Drug Reporting System (IDRS) to examine the feasibility of monitoring trends in the markets for 'party drugs'
    Libby Topp
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW 2052, Australia
    Drug Alcohol Depend 73:189-97. 2004
    ....
  91. ncbi request reprint The emergence of potent forms of methamphetamine in Sydney, Australia: a case study of the IDRS as a strategic early warning system
    Libby Topp
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia
    Drug Alcohol Rev 21:341-8. 2002
    ..Base and ice are more potent forms of methamphetamine than speed, and international experience, along with preliminary data obtained from the IDRS, suggest that their use is associated with harms in a number of domains...
  92. ncbi request reprint Polydrug use and overdose: overthrowing old myths
    Shane Darke
    Addiction 98:711. 2003