I J Cook

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi request reprint Relationships between spatial patterns of colonic pressure and individual movements of content
    I J Cook
    Department of Medicine, Royal Adelaide Hospital, University of Adelaide, Adelaide 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 278:G329-41. 2000
  2. ncbi request reprint Diagnosis and management of cricopharyngeal achalasia and other upper esophageal sphincter opening disorders
    I J Cook
    Department of Gastroenterology, University of New South Wales, St George Hospital, Kogarah, Australia
    Curr Gastroenterol Rep 2:191-5. 2000
  3. pmc The impact of laxative use upon symptoms in patients with proven slow transit constipation
    Phil G Dinning
    Department of Human Physiology, School of Medicine, Flinders University, Adelaide, SA 5042, Australia
    BMC Gastroenterol 11:121. 2011
  4. doi request reprint Diagnostic evaluation of dysphagia
    Ian J Cook
    Gastroenterology Department, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia
    Nat Clin Pract Gastroenterol Hepatol 5:393-403. 2008
  5. doi request reprint Oropharyngeal dysphagia
    Ian J Cook
    Department of Gastroenterology, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia
    Gastroenterol Clin North Am 38:411-31. 2009
  6. ncbi request reprint Chronic constipation: overview and challenges
    I J Cook
    University of New South Wales, Department of Gastroenterology, St George Hospital, Sydney, NSW, Australia
    Neurogastroenterol Motil 21:1-8. 2009
  7. ncbi request reprint Bowel preparation affects the amplitude and spatiotemporal organization of colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 22:633-e176. 2010
  8. doi request reprint Upregulation of the esophago-UES relaxation response: a possible pathophysiological mechanism in suspected reflux laryngitis
    M M Szczesniak
    University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 22:381-6, e89. 2010
  9. doi request reprint Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation
    P G Dinning
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 22:e340-9. 2010
  10. ncbi request reprint Intraluminal impedance detects failure of pharyngeal bolus clearance during swallowing: a validation study in adults with dysphagia
    M M Szczesniak
    Department of Gastroenterology, University of NSW and St George Hospital, Sydney, NSW, Australia
    Neurogastroenterol Motil 21:244-52. 2009

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Relationships between spatial patterns of colonic pressure and individual movements of content
    I J Cook
    Department of Medicine, Royal Adelaide Hospital, University of Adelaide, Adelaide 5000, Australia
    Am J Physiol Gastrointest Liver Physiol 278:G329-41. 2000
    ..The effectiveness of transport by a propagating sequence is influenced by its site of origin, amplitude, and velocity...
  2. ncbi request reprint Diagnosis and management of cricopharyngeal achalasia and other upper esophageal sphincter opening disorders
    I J Cook
    Department of Gastroenterology, University of New South Wales, St George Hospital, Kogarah, Australia
    Curr Gastroenterol Rep 2:191-5. 2000
    ..Medical and surgical options for improving pharyngeal clearance and minimizing aspiration are also discussed, as is the use of percutaneous esophageal gastrostomy feeding tubes...
  3. pmc The impact of laxative use upon symptoms in patients with proven slow transit constipation
    Phil G Dinning
    Department of Human Physiology, School of Medicine, Flinders University, Adelaide, SA 5042, Australia
    BMC Gastroenterol 11:121. 2011
    ..For many constipated patients laxative usage is ubiquitous and long standing. Our aim was to determine the impact of laxative use upon the stereotypic constipation descriptors...
  4. doi request reprint Diagnostic evaluation of dysphagia
    Ian J Cook
    Gastroenterology Department, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia
    Nat Clin Pract Gastroenterol Hepatol 5:393-403. 2008
    ..Stroke is the most common cause of pharyngeal dysphagia. A videoradiographic swallow study is vital in such cases to determine the extent and timing of aspiration and the severity and mechanics of dysfunction as a prelude to therapy...
  5. doi request reprint Oropharyngeal dysphagia
    Ian J Cook
    Department of Gastroenterology, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia
    Gastroenterol Clin North Am 38:411-31. 2009
    ..Such conditions include Parkinson disease, myositis, myasthenia, and thyrotoxicosis. Management is best delivered by a multidisciplinary team involving physician, speech pathologist, nutritionist and, at times, a surgeon...
  6. ncbi request reprint Chronic constipation: overview and challenges
    I J Cook
    University of New South Wales, Department of Gastroenterology, St George Hospital, Sydney, NSW, Australia
    Neurogastroenterol Motil 21:1-8. 2009
    ..The purpose of this supplement is to address critically the reasons for the current lack of understanding and to propose avenues of future research to address these deficiencies...
  7. ncbi request reprint Bowel preparation affects the amplitude and spatiotemporal organization of colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 22:633-e176. 2010
    ..There has been little systematic evaluation of the effects of bowel cleansing upon colonic propagating pressure wave sequences...
  8. doi request reprint Upregulation of the esophago-UES relaxation response: a possible pathophysiological mechanism in suspected reflux laryngitis
    M M Szczesniak
    University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 22:381-6, e89. 2010
    ..The aim was to determine whether the esophago-UES relaxation reflex induced by rapid esophageal distension is upregulated in patients with posterior laryngitis...
  9. doi request reprint Pancolonic spatiotemporal mapping reveals regional deficiencies in, and disorganization of colonic propagating pressure waves in severe constipation
    P G Dinning
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 22:e340-9. 2010
    ..Utilizing the technique of spatiotemporal mapping, we aimed to demonstrate 'manometric signatures' that may serve as biomarkers of the disorder...
  10. ncbi request reprint Intraluminal impedance detects failure of pharyngeal bolus clearance during swallowing: a validation study in adults with dysphagia
    M M Szczesniak
    Department of Gastroenterology, University of NSW and St George Hospital, Sydney, NSW, Australia
    Neurogastroenterol Motil 21:244-52. 2009
    ..62 in the proximal oesophagus. With the adoption of appropriate criteria, pharyngeal impedance measurement can accurately detect bolus passage and failed or impaired clearance during swallowing in patients with dysphagia...
  11. ncbi request reprint Prolonged multi-point recording of colonic manometry in the unprepared human colon: providing insight into potentially relevant pressure wave parameters
    P A Bampton
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, Australia
    Am J Gastroenterol 96:1838-48. 2001
    ..The study demonstrates differences between high amplitude propagating sequences and propagating sequence parameters that may have functional significance; and also, that the rectal motor complex is a ubiquitous pan colonic motor pattern...
  12. ncbi request reprint Twenty-four hour spatiotemporal mapping of colonic propagating sequences provides pathophysiological insight into constipation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1017-21. 2008
    ..Such graphical representation readily permits appreciation and identification of aberrant patterns in severe constipation and may be an important clinical and research tool in the assessment of colonic motor disorders...
  13. doi request reprint Spatio-temporal analysis reveals aberrant linkage among sequential propagating pressure wave sequences in patients with symptomatically defined obstructed defecation
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 21:945-e75. 2009
    ..Regional linkage may be important for normal colonic transit and loss of linkage might have pathophysiological relevance to and provide a useful biomarker of severe constipation...
  14. doi request reprint Evidence for oesophageal visceral hypersensitivity and aberrant symptom referral in patients with globus
    C L Chen
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, New South Wales, Australia
    Neurogastroenterol Motil 21:1142-e96. 2009
    ..The aberrant referral of oesophageal sensations in response to both mechanical and electrical stimulation supports the hypothesis that referral of symptoms to the neck might be a central phenomenon...
  15. doi request reprint Determinants of postprandial flow across the human ileocaecal junction: a combined manometric and scintigraphic study
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:1119-26. 2008
    ..We conclude that ileal PSs are highly propulsive and are the major determinant of episodic caecal filling and that caecal filling may be a major stimulus for caecal propagating sequences...
  16. ncbi request reprint Identification of impaired oesophageal bolus transit and clearance by secondary peristalsis in patients with non-obstructive dysphagia
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Kogarah, NSW, Australia
    Neurogastroenterol Motil 20:980-8. 2008
    ..Multichannel intraluminal impedance identifies functional defects of oesophageal bolus clearance by secondary peristalsis in NOD patients and such defects are characterized by a longer oesophageal dwell and a prolonged clearance time...
  17. doi request reprint Proximal colonic propagating pressure waves sequences and their relationship with movements of content in the proximal human colon
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia
    Neurogastroenterol Motil 20:512-20. 2008
    ..We conclude that proximal colonic PSs are highly propulsive and are a major determinant of proximal colonic flow...
  18. doi request reprint Optimal criteria for detecting bolus passage across the pharyngo-oesophageal segment during the normal swallow using intraluminal impedance recording
    M M Szczesniak
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 20:440-7. 2008
    ..Pharyngeal impedance provides an accurate, non-radiological indicator of bolus transit through the pharynx...
  19. ncbi request reprint Sacral nerve stimulation induces pan-colonic propagating pressure waves and increases defecation frequency in patients with slow-transit constipation
    P G Dinning
    Department of Medicine, University of New South Wales, Sydney, Australia
    Colorectal Dis 9:123-32. 2007
    ..The effects of SNS on colonic propagating sequences in constipation are unknown. Our aims were to evaluate the effect of SNS on colonic pressure patterns and evaluate its therapeutic potential in severe constipation...
  20. ncbi request reprint Validation of a semi-automated scintigraphic technique for detecting episodic, real-time colonic flow
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, New South Wales, Australia
    Neurogastroenterol Motil 18:547-55. 2006
    ....
  21. ncbi request reprint Space-time pressure structure of pharyngo-esophageal segment during swallowing
    R B Williams
    Department of Gastroenterology, St. George Hospital and University of New South Wales, Sydney, Australia
    Am J Physiol Gastrointest Liver Physiol 281:G1290-300. 2001
    ..Intrabolus pressure variations are highly dependent on position within the PE segment and time...
  22. ncbi request reprint Esophageal pneumatic dilation for postfundoplication dysphagia: safety, efficacy, and predictors of outcome
    J M Hui
    Departments of Gastroenterology, and Upper GI Surgery, The St George Hospital, University of New South Wales, Sydney, Australia
    Am J Gastroenterol 97:2986-91. 2002
    ..The aim of this study is to evaluate the clinical outcomes and the predictors of success for esophageal pneumatic dilations in patients with dysphagia after fundoplication...
  23. doi request reprint Low-resolution colonic manometry leads to a gross misinterpretation of the frequency and polarity of propagating sequences: Initial results from fiber-optic high-resolution manometry studies
    P G Dinning
    Departments of Gastroenterology and Surgery, Flinders Medical Centre, Flinders University, South Australia, Australia School of Medicine, University of New South Wales, New South Wales, Australia
    Neurogastroenterol Motil 25:e640-9. 2013
    ..High-resolution manometry catheters are now being used to record colonic motility. The aim of this study was to determine the influence of pressure sensor spacing on our ability to identify colonic propagating sequences (PS)...
  24. doi request reprint Modulation of esophageal afferent pathways by 5-HT3 receptor inhibition
    M M Szczesniak
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Neurogastroenterol Motil 25:383-8, e293. 2013
    ....
  25. doi request reprint Proximal versus distal oesophageal motility as assessed by combined impedance and manometry
    C L Chen
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Dig Liver Dis 41:104-9. 2009
    ..We investigated whether oesophageal motor function differs between the proximal and distal oesophagus...
  26. pmc Biomechanics, diagnosis, and treatment outcome in inflammatory myopathy presenting as oropharyngeal dysphagia
    R B Williams
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Gut 52:471-8. 2003
    ....
  27. doi request reprint Pancolonic motor response to subsensory and suprasensory sacral nerve stimulation in patients with slow-transit constipation
    P G Dinning
    Department of Human Physiology, Flinders University, Bedford Park, South Australia
    Br J Surg 99:1002-10. 2012
    ..This study evaluated the colonic motor response to subsensory and suprasensory SNS in patients with slow-transit constipation...
  28. doi request reprint Long-term outcome following pneumatic dilatation as initial therapy for idiopathic achalasia: an 18-year single-centre experience
    T R Elliott
    Department of Gastroenterology and Hepatology, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Aliment Pharmacol Ther 37:1210-9. 2013
    ..Relapse after treatment for idiopathic achalasia is common and long-term outcome data are limited...
  29. ncbi request reprint Removal of tonic nitrergic inhibition is a potent stimulus for human proximal colonic propagating sequences
    P G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, NSW 2217, Australia
    Neurogastroenterol Motil 18:37-44. 2006
    ..We conclude that blockade of NO synthesis has a stimulatory effect on the frequency of proximal colonic PS. This suggests removal of tonic nitrergic inhibition of the colon might be a physiological stimulus for propagating activity...
  30. ncbi request reprint Oropharyngeal scintigraphy: a reliable technique for the quantitative evaluation of oral-pharyngeal swallowing
    D W Shaw
    Department Medicine, Royal Adelaide Hospital, South Australia, Australia
    Dysphagia 19:36-42. 2004
    ..It may prove useful in assessment of dysphagia severity and longitudinal change...
  31. ncbi request reprint Predictors of outcome in an open label, therapeutic trial of high-dose omeprazole in laryngitis
    R B H Williams
    Department of Gastroenterology, St George Hospital, University of New South Wales, Sydney, Australia
    Am J Gastroenterol 99:777-85. 2004
    ..Gastroesophageal reflux is implicated in some cases of laryngitis. There are no established predictors of response to acid suppression therapy in suspected reflux laryngitis...
  32. ncbi request reprint The proximal colonic motor response to rectal mechanical and chemical stimulation
    P A Bampton
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia 2217
    Am J Physiol Gastrointest Liver Physiol 282:G443-9. 2002
    ..Rectal distension inhibits all colonic motor activity...
  33. ncbi request reprint Functional esophageal disorders
    Jean Paul Galmiche
    University of Nantes, Nantes, France
    Gastroenterology 130:1459-65. 2006
    ..Future research directions include further determination of fundamental mechanisms responsible for symptoms, development of novel management strategies, and definition of the most cost-effective diagnostic and treatment approaches...
  34. ncbi request reprint Biomechanics of failed deglutitive upper esophageal sphincter relaxation in neurogenic dysphagia
    Rohan B H Williams
    Department of Gastroenterology, The St George Hospital, The University of New South Wales, Sydney, New South Wales, 2217 Australia
    Am J Physiol Gastrointest Liver Physiol 283:G16-26. 2002
    ..In contrast, the stenotic UES displays a static loss of compliance, only apparent once the limit of sphincter expansion is reached...
  35. ncbi request reprint Impaired proximal colonic motor response to rectal mechanical and chemical stimulation in obstructed defecation
    Phil G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Sydney, Australia
    Dis Colon Rectum 48:1777-84. 2005
    ....
  36. ncbi request reprint Assessment of intraluminal impedance for the detection of pharyngeal bolus flow during swallowing in healthy adults
    Taher I Omari
    Department of Paediatrics, University of Adelaide, and Centre for Paediatric and Adolescent Gastroenterology, Women s and Children s Hospital, Adelaide, South Australia
    Am J Physiol Gastrointest Liver Physiol 290:G183-8. 2006
    ..Therefore, we conclude that intraluminal impedance measurement does not accurately reflect the bolus transit in the pharynx but does accurately reflect bolus transit across the UES and below...
  37. ncbi request reprint Abnormal predefecatory colonic motor patterns define constipation in obstructed defecation
    Philip G Dinning
    Department of Gastroenterology, The St George Hospital, University of New South Wales, Kogarah, New South Wales, Australia
    Gastroenterology 127:49-56. 2004
    ....
  38. ncbi request reprint Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow
    Anupam Pal
    Department of Mechanical Engineering, The Pennsylvania State Univ, Univ Park, PA 16802, USA
    Am J Physiol Gastrointest Liver Physiol 285:G1037-48. 2003
    ..Consequently, the location and magnitude of IBPG reflect the existence and location of abnormal constriction, and IBP and IBPG structure reflect decompensation of the pharyngeal swallow...