Terence C Chua

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. doi Impact of the peritoneal surface disease severity score on survival in patients with colorectal cancer peritoneal carcinomatosis undergoing complete cytoreduction and hyperthermic intraperitoneal chemotherapy
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, Australia
    Ann Surg Oncol 17:1330-6. 2010
  2. doi Colorectal liver metastases with extrahepatic disease--a new criteria for oncologic resection?
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital and St George Clinical School, University of New South Wales, Kogarah, Sydney, NSW, 2217, Australia
    J Gastrointest Cancer 43:502-4. 2012
  3. pmc Intraperitoneal chemotherapy in ovarian cancer: a review of tolerance and efficacy
    Daniel L Chan
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, and the St George Clinical School, University of New South Wales, St George Hospital, Kogarah, NSW, Australia
    Cancer Manag Res 4:413-22. 2012
  4. doi Iterative cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent peritoneal metastases
    Terence C Chua
    UNSW Department of Surgery St George Clinical School, University of New South Wales, Sydney, Australia
    J Surg Oncol 108:81-8. 2013
  5. doi Peritoneal mesothelioma: current status and future directions
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, NSW 2217, Australia
    Surg Oncol Clin N Am 21:635-43. 2012
  6. doi Resectable colorectal liver metastases: optimal sequencing of chemotherapy
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, St George Hospital, University of New South Wales, Kogarah, NSW, 2217, Sydney, Australia
    J Gastrointest Cancer 43:496-8. 2012
  7. doi Surgical management of melanoma lung metastasis: an analysis of survival outcomes in 292 consecutive patients
    Terence C Chua
    Melanoma Institute Australia, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 19:1774-81. 2012
  8. doi Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Terence C Chua
    University of New South Wales, St George Hospital, Sydney, Australia
    J Clin Oncol 30:2449-56. 2012
  9. doi Viewing metastatic colorectal cancer as a curable chronic disease
    Terence C Chua
    UNSW Department of Surgery, Cancer Care Centre, St George Hospital, Kogarah, Sydney, Australia
    Am J Clin Oncol 35:77-80. 2012
  10. pmc Evaluation of best supportive care and systemic chemotherapy as treatment stratified according to the retrospective peritoneal surface disease severity score (PSDSS) for peritoneal carcinomatosis of colorectal origin
    Joerg O W Pelz
    Department of General, Visceral, and Paediatric Surgery, University of Wuerzburg, Germany
    BMC Cancer 10:689. 2010

Detail Information

Publications89

  1. doi Impact of the peritoneal surface disease severity score on survival in patients with colorectal cancer peritoneal carcinomatosis undergoing complete cytoreduction and hyperthermic intraperitoneal chemotherapy
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, Australia
    Ann Surg Oncol 17:1330-6. 2010
    ..This study determines the impact on survival of the PSDS in a cohort of patients undergoing complete cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for CRPC...
  2. doi Colorectal liver metastases with extrahepatic disease--a new criteria for oncologic resection?
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital and St George Clinical School, University of New South Wales, Kogarah, Sydney, NSW, 2217, Australia
    J Gastrointest Cancer 43:502-4. 2012
    ..Emerging data suggest that in the current era of modern systemic therapies, resection of colorectal liver metastases with concomitant extrahepatic disease may be a curative option in selected patients...
  3. pmc Intraperitoneal chemotherapy in ovarian cancer: a review of tolerance and efficacy
    Daniel L Chan
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, and the St George Clinical School, University of New South Wales, St George Hospital, Kogarah, NSW, Australia
    Cancer Manag Res 4:413-22. 2012
    ....
  4. doi Iterative cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent peritoneal metastases
    Terence C Chua
    UNSW Department of Surgery St George Clinical School, University of New South Wales, Sydney, Australia
    J Surg Oncol 108:81-8. 2013
    ..This study examines the outcomes of iterative CRS (iCRS) HIPEC for treatment of recurrent peritoneal metastases...
  5. doi Peritoneal mesothelioma: current status and future directions
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, NSW 2217, Australia
    Surg Oncol Clin N Am 21:635-43. 2012
    ..This new staging system may form the basis of selecting patients for radical surgery and improve survival outcomes...
  6. doi Resectable colorectal liver metastases: optimal sequencing of chemotherapy
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, St George Hospital, University of New South Wales, Kogarah, NSW, 2217, Sydney, Australia
    J Gastrointest Cancer 43:496-8. 2012
    ..With the increasing availability of highly effective chemotherapy, surgery may be further advanced by the improved tumor response and better long-term outcomes associated with its use in the perioperative setting...
  7. doi Surgical management of melanoma lung metastasis: an analysis of survival outcomes in 292 consecutive patients
    Terence C Chua
    Melanoma Institute Australia, Royal Prince Alfred Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 19:1774-81. 2012
    ..This study sought to identify the clinicopathologic and predictors of outcome after surgical management of MLM in a large series of melanoma patients from a single institution...
  8. doi Early- and long-term outcome data of patients with pseudomyxoma peritonei from appendiceal origin treated by a strategy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
    Terence C Chua
    University of New South Wales, St George Hospital, Sydney, Australia
    J Clin Oncol 30:2449-56. 2012
    ..The purpose of our study was to evaluate outcome and long-term survival after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) consolidated through an international registry study...
  9. doi Viewing metastatic colorectal cancer as a curable chronic disease
    Terence C Chua
    UNSW Department of Surgery, Cancer Care Centre, St George Hospital, Kogarah, Sydney, Australia
    Am J Clin Oncol 35:77-80. 2012
    ....
  10. pmc Evaluation of best supportive care and systemic chemotherapy as treatment stratified according to the retrospective peritoneal surface disease severity score (PSDSS) for peritoneal carcinomatosis of colorectal origin
    Joerg O W Pelz
    Department of General, Visceral, and Paediatric Surgery, University of Wuerzburg, Germany
    BMC Cancer 10:689. 2010
    ..We evaluate the long-term survival of patients with peritoneal carcinomatosis (PC) treated with systemic chemotherapy regimens, and the impact of the of the retrospective peritoneal disease severity score (PSDSS) on outcomes...
  11. doi Influence of modern systemic therapies as adjunct to cytoreduction and perioperative intraperitoneal chemotherapy for patients with colorectal peritoneal carcinomatosis: a multicenter study
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, University of New South Wales, St George Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 18:1560-7. 2011
    ....
  12. doi Preoperative chemoradiation followed by surgical resection for resectable pancreatic cancer: a review of current results
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, University of New South Wales, Department of Surgery, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    Surg Oncol 20:e161-8. 2011
    ..There has been an interest in the interdisciplinary and multimodality approach that combines chemotherapy and radiation therapy as a preoperative treatment for patients with resectable pancreatic cancer...
  13. ncbi Surgical metastasectomy in AJCC stage IV M1c melanoma patients with gastrointestinal and liver metastases
    Terence C Chua
    Department of Surgery, St George Hospital, Sydney, Australia
    Ann Acad Med Singapore 39:634-9. 2010
    ..Given that systemic treatments in metastatic melanoma to date remains inadequate, we evaluated the efficacy of surgical metastasectomy on survival outcomes...
  14. doi Radiofrequency ablation of concomitant and recurrent pulmonary metastases after surgery for colorectal liver metastases
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 19:75-81. 2012
    ..To evaluate our experience of radiofrequency ablation (RFA) of pulmonary metastases in patients with resected colorectal liver metastases who had concomitant or recurrent pulmonary metastases...
  15. doi Trends in surgical oncology research in Australia during the period 1998-2009--a bibliometric review
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Kogarah, NSW 2217, Australia
    J Surg Oncol 104:216-9. 2011
    ..To evaluate the distribution and scope of surgical research in Australia relating to malignant diseases in the field of surgery...
  16. doi Intraoperative hyperthermic intraperitoneal chemotherapy after cytoreductive surgery in ovarian cancer peritoneal carcinomatosis: systematic review of current results
    Terence C Chua
    Department of Surgery, St George Hospital, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    J Cancer Res Clin Oncol 135:1637-45. 2009
    ..We collectively review studies in the literature that report the efficacy of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for ovarian cancer peritoneal carcinomatosis...
  17. doi Critical analysis of 33 patients with peritoneal carcinomatosis secondary to colorectal and appendiceal signet ring cell carcinoma
    Terence C Chua
    UNSW Department of Surgery, St George Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 16:2765-70. 2009
    ..The majority of patients develop peritoneal carcinomatosis (PC) early in the disease. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) may potentially improve survival...
  18. doi Surgical therapies in metastatic colorectal cancer with a potential for cure
    Terence C Chua
    Department of Surgery, St George Hospital, Sydney, Australia
    Am J Clin Oncol 34:326-31. 2011
    ..Emerging evidence suggests that in selected patients, these procedures are safe and may be beneficial in contributing to long-term survival...
  19. doi Determining the association between preoperative computed tomography findings and postoperative outcomes after cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei
    Terence C Chua
    UNSW Department of Surgery, St George Hospital, Kogarah, Sydney, NSW, Australia
    Ann Surg Oncol 18:1582-9. 2011
    ..This study evaluates the accuracy of computed tomography (CT) scoring of the peritoneal cancer index (PCI) and examines its association with surgical morbidity and outcomes in pseudomyxoma peritonei...
  20. ncbi Successful right hepatectomy after four treatments of yttrium-90 microspheres (SIR-Spheres) and concomitant FOLFOX as bridging therapy to resection of colorectal liver metastases
    Terence C Chua
    University of New South Wales, Department of Surgery, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    Anticancer Res 30:3005-7. 2010
    ..This case demonstrates the feasibility and potential use of this management strategy to expand the role of successful therapies that will bridge the road towards curative liver resection...
  21. doi Extended pancreaticoduodenectomy with vascular resection for pancreatic cancer: a systematic review
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    J Gastrointest Surg 14:1442-52. 2010
    ....
  22. doi Upfront compared to delayed cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei is associated with considerably lower perioperative morbidity and recurrence rate
    Terence C Chua
    UNSW Department of Surgery, Cancer Care Centre, St George Hospital, Kogarah, Sydney, Australia
    Ann Surg 253:769-73. 2011
    ..We seek to evaluate the outcomes of patients treated upfront with CRS PIC compared to patients undergoing delayed CRS PIC as salvage or treatment for recurrences after initial debulking surgery...
  23. doi Evolution of locoregional treatment for peritoneal carcinomatosis: single-center experience of 308 procedures of cytoreductive surgery and perioperative intraperitoneal chemotherapy
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, Australia
    Am J Surg 201:149-56. 2011
    ....
  24. doi Morbidity and mortality outcomes of cytoreductive surgery and perioperative intraperitoneal chemotherapy at a single tertiary institution: towards a new perspective of this treatment
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, Australia
    Ann Surg 251:101-6. 2010
    ..The aim of this study was to report the perioperative outcomes of CRS and PIC from a single institution to review factors that are associated with a poor perioperative outcome...
  25. doi Two decades of experience with hepatic cryotherapy for advanced colorectal metastases
    Keh M Ng
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Ann Surg Oncol 19:1276-83. 2012
    ..Ablative therapies may extend this. This study reports a single institution's long-term experience with hepatic cryotherapy for advanced CLM...
  26. doi Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma: multi-institutional experience
    Tristan D Yan
    Department of Surgery, St George Hospital, and Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
    J Clin Oncol 27:6237-42. 2009
    ..This multi-institutional registry study evaluated cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for diffuse malignant peritoneal mesothelioma (DMPM)...
  27. doi Secondary cytoreduction and perioperative intraperitoneal chemotherapy after initial debulking of pseudomyxoma peritonei: a study of timing and the impact of malignant dedifferentiation
    Terence C Chua
    Department of Surgery, University of New South Wales, Kogarah, Sydney, Australia
    J Am Coll Surg 211:526-35. 2010
    ..This study investigates its role as a secondary definitive treatment procedure after earlier primary treatments...
  28. doi Palliative effects of an incomplete cytoreduction combined with perioperative intraperitoneal chemotherapy
    Terence C Chua
    Department of Surgery, St George Hospital, University of New South Wales, Kogarah, Australia
    Am J Clin Oncol 33:568-71. 2010
    ..The outcome of an incomplete cytoreduction followed by administering perioperative intraperitoneal chemotherapy on whether it prolongs survival or palliates symptoms is yet to be established...
  29. doi Improved outcomes after aggressive surgical resection of hilar cholangiocarcinoma: a critical analysis of recurrence and survival
    Akshat Saxena
    Department of Surgery, Hepatobiliary and Surgical Oncology Unit, University of New South Wales, St George Hospital, Level 3 Pitney Building, Short St, Kogarah, New South Wales 2217, Sydney, Australia
    Am J Surg 202:310-20. 2011
    ..Hilar cholangiocarcinoma (HC) is invariably fatal without surgical intervention. The primary aim of the current study was to report overall survival and recurrence-free survival outcomes after surgical resection of HC...
  30. doi Significance of lymph node metastasis in patients with colorectal cancer peritoneal carcinomatosis
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, Australia
    World J Surg 33:1488-94. 2009
    ..Lymphatic metastasis reflects a systemic spread of cancer and its implication on patients who undergo cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC) for carcinomatosis needs to be studied...
  31. doi Critical assessment of risk factors for complications after cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei
    Akshat Saxena
    Department of Surgery, St George Hospital, University of New South Wales, Sydney, Australia
    Ann Surg Oncol 17:1291-301. 2010
    ..This study evaluates the clinical and treatment-related risk factors for perioperative morbidity and mortality in PMP patients who underwent CRS and PIC...
  32. ncbi Impact of tumor angiogenesis in peritoneal mesothelioma after radical cytoreduction and hyperthermic intraperitoneal chemotherapy
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, 2217, Australia
    Pathol Oncol Res 16:217-22. 2010
    ....
  33. ncbi The importance of gender in patients with peritoneal metastases of appendiceal origin treated by cytoreduction and intraperitoneal chemotherapy: an analysis of 257 consecutive patients from an Australian centre
    Lawson Ung
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Kogarah, Sydney, NSW, 2217, Australia
    J Cancer Res Clin Oncol 140:1037-45. 2014
    ..Our aim is to investigate the gender differences for metastatic epithelial neoplasms of the appendix treated by cytoreductive surgery (CS) and intraperitoneal chemotherapy (IPC)...
  34. doi Outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: the Australian experience
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, Australia
    J Surg Oncol 99:109-13. 2009
    ..This paper reports the outcomes of cytoreductive surgery (CRS) and Hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of this disease...
  35. ncbi Optimizing the surgical effort in patients with advanced neuroendocrine neoplasm hepatic metastases: a critical analysis of 40 patients treated by hepatic resection and cryoablation
    Akshat Saxena
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Kogarah, Sydney, Australia
    Am J Clin Oncol 35:439-45. 2012
    ..The present study critically evaluates the progression-free survival (PFS) and overall survival (OS) of patients with NENHM who underwent concomitant hepatic resection and cryoablation...
  36. doi Inflammatory markers in blood and serum tumor markers predict survival in patients with epithelial appendiceal neoplasms undergoing surgical cytoreduction and intraperitoneal chemotherapy
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Sydney, New South Wales, Australia
    Ann Surg 256:342-9. 2012
    ..The study examines the role inflammatory and tumor markers as biomarkers to preoperatively predict outcome in patients with epithelial appendiceal neoplasm undergoing cytoreduction and intraperitoneal chemotherapy...
  37. doi Liver-directed therapy for neuroendocrine neoplasm hepatic metastasis prolongs survival following progression after initial surgery
    Akshat Saxena
    UNSW Department of Surgery, St George Hospital, Kogarah, Sydney, New South Wales, Australia
    J Surg Oncol 105:342-50. 2012
    ..No previous study has addressed the outcomes after treatment of hepatic disease progression in patients who initially underwent surgical extirpation of NENHM. This was the principal aim of the current study...
  38. doi Postoperative pancreatic fistula after cytoreductive surgery and perioperative intraperitoneal chemotherapy: incidence, risk factors, management, and clinical sequelae
    Akshat Saxena
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, Australia
    Ann Surg Oncol 17:1302-10. 2010
    ..This study evaluates the morbidity of postoperative pancreatic fistula (PF) within the context of CRS and PIC...
  39. doi Radiofrequency ablation as an adjunct to systemic chemotherapy for colorectal pulmonary metastases
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, NSW, Sydney, Australia
    Cancer 116:2106-14. 2010
    ..Based on previously documented efficacy of this treatment, the authors retrospectively studied the prognostic factors for long-term survival...
  40. doi Systematic review of neoadjuvant transarterial chemoembolization for resectable hepatocellular carcinoma
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, Australia
    Liver Int 30:166-74. 2010
    ..However, it does not appear to improve DFS...
  41. ncbi Clinicopathologic and treatment-related factors influencing recurrence and survival after hepatic resection of intrahepatic cholangiocarcinoma: a 19-year experience from an established Australian hepatobiliary unit
    Akshat Saxena
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    J Gastrointest Surg 14:1128-38. 2010
    ..The secondary aim is to evaluate the impact of prognostic variables on outcomes...
  42. doi Evaluation of the cost-effectiveness of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (peritonectomy) at the St George Hospital peritoneal surface malignancy program
    Terence C Chua
    Department of Surgery, University of New South Wales, Sydney, NSW, Australia
    Ann Surg 251:323-9. 2010
    ..This report aims to measure and describe the survival outcomes and health care cost associated with CRS and HIPEC for peritoneal surface malignancies at a centralized tertiary institution in Australia...
  43. doi Hepatic resection with or without adjuvant iodine-131-lipiodol for hepatocellular carcinoma: a comparative analysis
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, St George Hospital, University of New South Wales, Kogarah, Sydney, NSW 2217, Australia
    Int J Clin Oncol 16:125-32. 2011
    ..This study evaluates the efficacy of adjuvant iodine-131-lipiodol after hepatic resection through the experience of a single-center hepatobiliary service of managing this disease...
  44. doi Anticancer effect of bromelain with and without cisplatin or 5-FU on malignant peritoneal mesothelioma cells
    Krishna Pillai
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, New South Wales, Australia
    Anticancer Drugs 25:150-60. 2014
    ..However, 5-FU with bromelain did not show any significant increase in cytotoxicity. Bromelain-induced cell death is by apoptosis and autophagy. Bromelain has the potential of being developed as a therapeutic agent in MPM. ..
  45. doi Hepatectomy and resection of concomitant extrahepatic disease for colorectal liver metastases--a systematic review
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, University of New South Wales, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    Eur J Cancer 48:1757-65. 2012
    ..The authors examine the clinical efficacy of this treatment approach through a systematic review of the published literature...
  46. doi Risk factors for massive blood transfusion in cytoreductive surgery: a multivariate analysis of 243 procedures
    Akshat Saxena
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, Australia
    Ann Surg Oncol 16:2195-203. 2009
    ..Our study is the first of its kind to evaluate the risk factors for intraoperative MABT in peritonectomy procedures...
  47. doi Surgical cytoreduction and survival in appendiceal cancer peritoneal carcinomatosis: an evaluation of 46 consecutive patients
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Sydney, NSW, Australia
    Ann Surg Oncol 18:1540-6. 2011
    ..The survival of patients with neoplasms of malignant character is protracted and this study was designed to evaluate the effectiveness of this surgical strategy on outcomes...
  48. doi Progression and survival results after radical hepatic metastasectomy of indolent advanced neuroendocrine neoplasms (NENs) supports an aggressive surgical approach
    Akshat Saxena
    Department of Surgery, St George Hospital, The University of New South Wales, Kogarah, Sydney, Australia
    Surgery 149:209-20. 2011
    ..As a secondary endpoint, the prognostic factors associated with progression-free survival and overall survival were evaluated...
  49. ncbi A formulation for in situ lysis of mucin secreted in pseudomyxoma peritonei
    Krishna Pillai
    UNSW Department of Surgery, St George Clinical School, Kogarah, NSW, Australia
    Int J Cancer 134:478-86. 2014
    ..0, when tested in a rat model implanted with 3 g of mucin intraperitoneally (IP). IP administration of the drug in a rat model of PMP was shown to result in mucin disintegration within 72 hr with no toxicity observed...
  50. doi Comparative analysis of perioperative intraperitoneal chemotherapy regimen in appendiceal and colorectal peritoneal carcinomatosis
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, St George Hospital, University of New South Wales, Level 3 Pitney Building, Gray Street, Kogarah, Sydney, NSW, 2217, Australia
    Int J Clin Oncol 18:439-46. 2013
    ..The relative survival benefits of each or both regimens are explored in this large series of patients undergoing cytoreduction at a single institution...
  51. doi Long-term survival in patients with pseudomyxoma peritonei treated with cytoreductive surgery and perioperative intraperitoneal chemotherapy: 10 years of experience from a single institution
    Terence C Chua
    Department of Surgery, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Ann Surg Oncol 16:1903-11. 2009
    ..This study reports the survival outcomes, clinicopathological prognostic factors, and a learning curve from a single institution's experience...
  52. doi Summary of current therapeutic options for peritoneal metastases from colorectal cancer
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, University of New South Wales, St George Hospital, Sydney, Australia
    J Surg Oncol 107:566-73. 2013
    ..Peritoneal metastases remain an under addressed problem for which this review serves to investigate the efficacy of systemic chemotherapy and radical surgical treatments in this disease entity...
  53. doi Therapeutic potential of surgery for metastatic colorectal cancer
    Terence C Chua
    UNSW Department of Surgery, Hepatobiliary and Surgical Oncology Unit, St George Hospital, Sydney, Australia
    Scand J Gastroenterol 47:258-68. 2012
    ..The purpose of this article is to provide a comprehensive review of the therapeutic advances in the surgical management of metastatic colorectal cancer...
  54. doi Thoracic cytoreductive surgery and intraoperative hyperthermic intrathoracic chemotherapy for pseudomyxoma peritonei
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW, Australia
    J Surg Oncol 99:292-5. 2009
    ..We review our experience with thoracic cytoreductive surgery (CRS) and intraoperative hyperthermic intrathoracic chemotherapy (HITHOC) for the treatment of pleural recurrence of PMP following previous intraabdominal surgery...
  55. doi Salvage cytoreduction for chemorefractory ovarian cancer with peritoneal carcinomatosis: a last chance or futile efforts?
    Terence C Chua
    UNSW Department of Surgery, Cancer Care Centre, St George Hospital, Kogarah, Sydney, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 50:478-84. 2010
    ..The objective of this study was to evaluate if cytoreduction of peritoneal carcinomatosis in patients with chemorefractory recurrent ovarian cancer as salvage treatment confers any survival benefits...
  56. doi Hepatic resection for metastatic breast cancer: a systematic review
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Sydney, Australia
    Eur J Cancer 47:2282-90. 2011
    ..A systematic review was undertaken to define its safety, efficacy and to identify prognostic factors associated with survival...
  57. doi Clinicopathological determinants of survival after hepatic resection of hepatocellular carcinoma in 97 patients--experience from an Australian hepatobiliary unit
    Terence C Chua
    University of New South Wales Department of Surgery, St George Hospital, Level 3 Pitney Building, Gray Street, Kogarah, Sydney, 2217, NSW, Australia
    J Gastrointest Surg 14:1370-80. 2010
    ..Through evaluation of a center's experience with treatment of a disease, determinants unique to the treated patient cohort may be identified...
  58. doi Intra-arterial iodine-131-lipiodol for unresectable hepatocellular carcinoma
    Terence C Chua
    Department of Surgery, St George Hospital, Kogarah, University of New South Wales, Sydney, New South Wales, Australia
    Cancer 116:4069-77. 2010
    ..Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative setting is warranted...
  59. ncbi Risk factors and clinicopathological study of prognostic factors in the peritoneal mesothelioma
    Edward C G Tudor
    University of New South Wales, Department of Surgery, St George Hospital, Kogarah, Sydney, Australia
    Am Surg 76:400-5. 2010
    ..01). Risk factors identified to be prognostic for survival include the female gender, not smoking, not consuming alcohol, and an epithelioid tumor type. Treatment factor associated with an improved survival was a complete cytoreduction...
  60. doi Should the treatment of peritoneal carcinomatosis by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy still be regarded as a highly morbid procedure?: a systematic review of morbidity and mortality
    Terence C Chua
    Department of Surgery, St George Hospital, University of New South Wales, Sydney, Australia
    Ann Surg 249:900-7. 2009
    ..This consequentially resulted in a lack of randomized trials being conducted and translates into a lack of the most reliable form of scientific evidence in clinical research, hence limiting its general acceptance...
  61. doi Factors predicting response and survival after yttrium-90 radioembolization of unresectable neuroendocrine tumor liver metastases: a critical appraisal of 48 cases
    Akshat Saxena
    Department of Surgery, University of New South Wales, St George Hospital, Sydney, New South Wales, Australia
    Ann Surg 251:910-6. 2010
    ..As a secondary outcome, the impact of this treatment on serologic toxicity was assessed...
  62. doi Summary outcomes of two-stage resection for advanced colorectal liver metastases
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, University of New South Wales, Kogarah, Sydney, New South Wales, Australia
    J Surg Oncol 107:211-6. 2013
    ..Two-stage resection (TSR) allows selected patients to achieve complete resection when combined with chemotherapy and interventional radiological procedures...
  63. doi Early recurrence of pseudomyxoma peritonei following treatment failure of cytoreductive surgery and perioperative intraperitoneal chemotherapy is indicative of a poor survival outcome
    Terence C Chua
    UNSW Department of Surgery, Hepatobiliary and Surgical Oncology Unit, St George Hospital, Sydney, NSW, 2217, Australia
    Int J Colorectal Dis 27:381-9. 2012
    ..The aim of this study was to identify predictors of early recurrence to optimize outcomes...
  64. doi Radioembolization versus standard care of hepatic metastases: comparative retrospective cohort study of survival outcomes and adverse events in salvage patients
    Lourens Bester
    Department of Interventional Radiology, University of New South Wales, St Vincent s Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia
    J Vasc Interv Radiol 23:96-105. 2012
    ....
  65. doi Radioembolization and systemic chemotherapy improves response and survival for unresectable colorectal liver metastases
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, Department of Surgery, University of New South Wales, St George Hospital, Sydney, NSW, Australia
    J Cancer Res Clin Oncol 137:865-73. 2011
    ..To evaluate the role of radioembolization and systemic chemotherapy as a combined modality therapy for unresectable colorectal liver metastases...
  66. doi Feasibility of ablation as an alternative to surgical metastasectomy in patients with unresectable sarcoma pulmonary metastases
    Jesslyn H Ding
    Department of Surgery, St George Hospital, University of New South Wales, Level 3 Pitney Building, Gray Street, Kogarah, NSW 2217, Sydney, Australia
    Interact Cardiovasc Thorac Surg 9:1051-3. 2009
    ..0 months with a range of 4.0-35.0 months. Three of four patients underwent the procedure uneventfully. RFA is a safe and minimally invasive intervention in non-surgical candidates with sarcoma pulmonary metastases...
  67. doi Predictors of cure after hepatic resection of colorectal liver metastases: an analysis of actual 5- and 10-year survivors
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital, Kogarah NSW 2217, Sydney, Australia
    J Surg Oncol 103:796-800. 2011
    ..Limited data exists on outcomes of patients beyond 5 years. Studying the rates of cure and predictive factors for cure are essential to define the true benefit of this therapy...
  68. ncbi Potential mucolytic agents for mucinous ascites from pseudomyxoma peritonei
    Krishna Pillai
    Department of Surgery Cancer Research Laboratories, University of New South Wales, Sydney, Australia
    Invest New Drugs 30:2080-6. 2012
    ..A variety of potential mucolytic agents are explored in this review providing evidence of basic biochemical evidence of its efficacy with potential translational application...
  69. doi Exploring the role of resection of extrahepatic metastases from hepatocellular carcinoma
    Terence C Chua
    Hepatobiliary and Surgical Oncology Unit, University of New South Wales UNSW, Department of Surgery, Short Street, St George Hospital, Kogarah, NSW 2217, Sydney, Australia
    Surg Oncol 21:95-101. 2012
    ..A registry study to pull the results of case reports and institutional experiences may be useful in cumulating evidence of this practice...
  70. doi Surgery for colorectal peritoneal carcinomatosis
    Terence C Chua
    UNSW Department of Surgery, Hepatobiliary and Surgical Oncology Unit, St George Hospital, Sydney, Australia
    Scand J Gastroenterol 47:277-85. 2012
    ..This review provides a summary of the developments in the understanding and treatment of peritoneal surface malignancy from colorectal cancer...
  71. doi Hepatic resection for transplantable hepatocellular carcinoma for patients within Milan and UCSF criteria
    Terence C Chua
    Department of Surgery, Hepatobiliary and Surgical Oncology Unit, University of New South Wales, St George Hospital, Kogarah, Sydney, Australia
    Am J Clin Oncol 35:141-5. 2012
    ..Hence, the second option of hepatic resection must be considered. The aim of this study is to report the results of hepatic resection in transplantable patients...
  72. doi Systematic review of randomized and nonrandomized trials of the clinical response and outcomes of neoadjuvant systemic chemotherapy for resectable colorectal liver metastases
    Terence C Chua
    Department of Surgery, St George Hospital, University of New South Wales, Kogarah, Sydney, Australia
    Ann Surg Oncol 17:492-501. 2010
    ..There is argument over the oncologic benefit of this practice in patients who would already be suitable for a curative hepatectomy...
  73. ncbi In vivo model of pseudomyxoma peritonei for novel candidate drug discovery
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, Sydney, NSW 2217, Australia
    Anticancer Res 29:4051-5. 2009
    ..Over 90 days, all rats developed PMP indicating that this in vivo animal model may become useful platform in a drug discovery program to allow drug efficacy testing against human PMP...
  74. doi Yttrium-90 radiotherapy for unresectable intrahepatic cholangiocarcinoma: a preliminary assessment of this novel treatment option
    Akshat Saxena
    Department of Surgery, St George Hospital, University of New South Wales, Sydney, NSW, Australia
    Ann Surg Oncol 17:484-91. 2010
    ..The objective of this study was to present data on the safety and efficacy of a novel treatment option, yttrium-90 ((90)Y) radioembolization for unresectable ICC...
  75. doi Cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, NSW, Sydney, Australia
    J Surg Oncol 100:139-43. 2009
    ..We review our experience with small bowel peritoneal carcinomatosis following treatment with cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC)...
  76. doi Differential expression of Ki-67 and sex steroid hormone receptors between genders in peritoneal mesothelioma
    Terence C Chua
    UNSW Department of Surgery, Cancer Research Laboratory, St George Hospital, Kogarah, Sydney, NSW 2217, Australia
    Pathol Oncol Res 15:671-8. 2009
    ..Once the exact functional effects of these receptors are understood, the use of established therapeutic options that are clinically available to target the sex steroid pathway may become a reality...
  77. doi Second-line treatment of first relapse recurrent ovarian cancer
    Terence C Chua
    UNSW Department of Surgery, Cancer Care Centre, St George Hospital, Kogarah, Sydney, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 50:465-71. 2010
    ....
  78. ncbi Hepatocellular carcinoma peritoneal metastases: report of three cases and collective review of the literature
    Jesslyn H Ding
    Department of Surgery, University of New South Wales, St George Hospital, Kogarah, NSW, Sydney, Australia
    Ann Acad Med Singapore 39:734-4. 2010
    ..Localised PM may now be adequately controlled and managed with cytoreductive surgery (CRS)...
  79. doi Outcomes of single-centre experience of hepatic resection and cryoablation of sarcoma liver metastases
    Terence C Chua
    Department of Surgery, University of New South Wales, St George Hospital, New South Wales, Sydney, Australia
    Am J Clin Oncol 34:317-20. 2011
    ..Surgery remains paramount in sarcoma management; however, there is inadequate literature reporting the role of hepatic surgery as treatment for sarcoma liver metastases...
  80. pmc Surgical biology for the clinician: peritoneal mesothelioma: current understanding and management
    Terence C Chua
    University of New South Wales, Department of Surgery, St George Hospital, Kogarah, New South Wales, Sydney, Australia
    Can J Surg 52:59-64. 2009
    ..We update on the current understanding of peritoneal mesothelioma from a clinical perspective in hope that greater clinician awareness will promote best practice management of this condition...
  81. doi Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review
    Terence C Chua
    Neuropsychiatric Institute, Euroa Centre, Prince of Wales Hospital, Randwick, NSW, Australia
    Curr Opin Neurol 21:83-92. 2008
    ..To provide a comprehensive review of diffusion tensor imaging in evaluating microstructural changes in the spectrum of cognitive decline from ageing to Alzheimer's disease, in particular focusing on mild cognitive impairment...
  82. ncbi Upfront compared to delayed cytoreductive surgery and perioperative intraperitoneal chemotherapy for pseudomyxoma peritonei is associated with considerably lower perioperative morbidity and recurrence rate
    Terence C Chua
    UNSW Department of Surgery Department of Medical Oncology, Cancer Care Centre, St George Hospital, Kogarah, Sydney, Australia
    Ann Surg 253:769-73. 2011
    ..We seek to evaluate the outcomes of patients treated upfront with CRS PIC compared to patients undergoing delayed CRS PIC as salvage or treatment for recurrences after initial debulking surgery...
  83. doi Diffuse malignant peritoneal mesothelioma--an update on treatment
    Peyman Mirarabshahii
    Cancer Research Laboratories, Department of Surgery, St George Hospital, Sydney, Australia
    Cancer Treat Rev 38:605-12. 2012
    ..This article describes how the prognosis of the disease has changed over the last decade...
  84. doi Hand-assisted laparoscopic partial nephrectomy: a controlled study of bipolar inline radiofrequency ablation device in Swine
    - Peng Yao
    University of New South Wales, St George Hospital, Sydney, New South Wales, Australia
    Surg Innov 17:57-62. 2010
    ..Bipolar inline radiofrequency ablation (ILRFA) is an effective way to control bleeding during parenchymal organ transection. This was investigated in a study of laparoscopic hand-assisted partial nephrectomy in swine...
  85. ncbi New treatments and outcomes in peritoneal carcinomatosis
    Terence C Chua
    Department of Surgery, University of New South Wales, Sydney, NSW
    Med J Aust 191:3-4. 2009
    ..Evidence-based therapies offer hope of prolonged survival for selected patients with this disease...
  86. ncbi Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment
    Terence C Chua
    School of Psychiatry, University of New South Wales, NSW, Australia
    Am J Geriatr Psychiatry 17:602-13. 2009
    ..Biomarkers may help identify individuals at greatest risk of progressive decline. The authors examine a novel neuroimaging technique, diffusion tensor imaging (DTI) as a potential biomarker of MCI...
  87. doi Outcomes of elderly patients undergoing cytoreductive surgery and perioperative intraperitoneal chemotherapy for colorectal cancer peritoneal carcinomatosis
    Yvonne L B Klaver
    Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands
    J Surg Oncol 105:113-8. 2012
    ..With technical maturity and improved perioperative care, we examined the outcomes of elderly patients undergoing CRS and PIC for colorectal PC...