Research Topics
| Alan CassSummaryAffiliation: University of Sydney Country: Australia Publications
| Collaborators
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Detail Information
Publications
The cost-effectiveness of sentinel node biopsy in patients with intermediate thickness primary cutaneous melanomaR L Morton
Sydney Melanoma Unit, Discipline of Surgery, The University of Sydney, Sydney, NSW, Australia
Ann Surg Oncol 16:929-40. 2009..The aim of this study was to determine the cost-effectiveness of wide excision (WEX) + sentinel node biopsy (SNB) compared with WEX only in patients with primary melanomas >/=1 mm in thickness...- Patient views about treatment of stage 5 CKD: a qualitative analysis of semistructured interviewsRachael L Morton
School of Public Health, University of Sydney, Sydney, Australia
Am J Kidney Dis 55:431-40. 2010.... - The cost-effectiveness of induction immunosuppression in kidney transplantationRachael L Morton
School of Public Health, The University of Sydney, Sydney, NSW, Australia
Nephrol Dial Transplant 24:2258-69. 2009..This study evaluated the cost-effectiveness of antibody induction comparing interleukin-2 receptor antagonists (IL2Ra) to standard therapy with no induction or induction with polyclonal antibodies... 
The views of patients and carers in treatment decision making for chronic kidney disease: systematic review and thematic synthesis of qualitative studiesR L Morton
Sydney School of Public Health, University of Sydney, Sydney, NSW 2006, Australia
BMJ 340:c112. 2010..To synthesise the views of patients and carers in decision making regarding treatment for chronic kidney disease, and to determine which factors influence those decisions...- Lowering blood pressure reduces renal events in type 2 diabetesBastiaan E De Galan
George Institute for International Health, University of Sydney, Sydney, NSW, Australia
J Am Soc Nephrol 20:883-92. 2009..We could not identify a BP threshold below which renal benefit is lost... 
Efficacy and safety of routine blood pressure lowering in older patients with diabetes: results from the ADVANCE trialToshiharu Ninomiya
The George Institute for International Health, University of Sydney, New South Wales, Australia
J Hypertens 28:1141-9. 2010....- Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trialSophia Zoungas
The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Diabetes Care 32:2068-74. 2009..To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes... - Cardiovascular risk management in chronic kidney disease in general practice (the AusHEART study)Mona Razavian
The George Institute for Global Health, Sydney, Australia
Nephrol Dial Transplant 27:1396-402. 2012..The objectives of this study were to assess the prevalence, general practitioner (GP) awareness and extent of current evidence-practice gaps in the management of CKD in Australian primary care... - Aspirin is beneficial in hypertensive patients with chronic kidney disease: a post-hoc subgroup analysis of a randomized controlled trialMeg J Jardine
The George Institute for Global Health, Sydney, Australia Concord Repatriation General Hospital, Sydney, Australia
J Am Coll Cardiol 56:956-65. 2010..The purpose of this study was to determine the benefit and risk associated with antiplatelet therapy in the chronic kidney disease (CKD) population... - Factors that influence the decision to be an organ donor: a systematic review of the qualitative literatureMichelle J Irving
School of Public Health, The University of Sydney, Sydney, Australia
Nephrol Dial Transplant 27:2526-33. 2012..We conducted a systematic review of qualitative studies that explored community attitudes towards living and deceased solid organ donation to inform strategies to improve organ donation rates... - Cost-effectiveness of screening and optimal management for diabetes, hypertension, and chronic kidney disease: a modeled analysisKirsten Howard
School of Public Health, University of Sydney, and The Royal Prince Alfred Hospital, Sydney, NSW, Australia
Value Health 13:196-208. 2010..We therefore sought to estimate the costs and health outcomes of alternative strategies to prevent end-stage kidney disease, compared with usual care... - Disparities between prescribing of secondary prevention therapies for stroke and coronary artery disease in general practiceEmma Heeley
The George Institute for Global Health, Royal Prince Alfred Hospital and University of Sydney, Sydney, NSW, Australia
Int J Stroke 7:649-54. 2012..Extensive evidence exists regarding the effectiveness of secondary prevention measures in patients with cardiovascular disease... - Prediction of kidney-related outcomes in patients with type 2 diabetesMeg J Jardine
George Institute For Global Health, Sydney, Australia
Am J Kidney Dis 60:770-8. 2012..Tools are needed to predict which individuals with diabetes will develop kidney disease and its complications... - Patient preferences for the allocation of deceased donor kidneys for transplantation: a mixed methods studyAllison Tong
Sydney School of Public Health, The University of Sydney, Sydney, NSW 2006, Australia
BMC Nephrol 13:18. 2012..Deceased donor kidneys are a scarce health resource, yet patient preferences for organ allocation are largely unknown. The aim of this study was to determine patient preferences for how kidneys should be allocated for transplantation... - Nephrologists' perspectives on waitlisting and allocation of deceased donor kidneys for transplantAllison Tong
Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW, Australia
Am J Kidney Dis 58:704-16. 2011..This study aims to elicit nephrologists' perspectives on waitlisting patients for kidney transplant and the allocation of deceased kidneys... - If you can't comply with dialysis, how do you expect me to trust you with transplantation? Australian nephrologists' views on indigenous Australians' 'non-compliance' and their suitability for kidney transplantationKate Anderson
The George Institute for Global Health, Sydney, Australia
Int J Equity Health 11:21. 2012.... - Alcohol consumption and 5-year onset of chronic kidney disease: the AusDiab studySarah L White
The George Institute for International Health, Sydney, Australia
Nephrol Dial Transplant 24:2464-72. 2009..Excessive alcohol consumption is a risk factor for hypertension and stroke; however, evidence for an association with chronic kidney disease is conflicting... - Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney diseaseHiddo J Lambers Heerspink
The George Institute for International Health, University of Sydney, Missenden Road, Camperdown, Sydney, NSW 2050, Australia
Eur Heart J 31:2888-96. 2010..In these analyses of the ADVANCE trial, we assessed the effects of a fixed combination of perindopril-indapamide on renal and cardiovascular outcomes in patients with type 2 diabetes according to baseline CKD stage... - The risk of cancer in people with diabetes and chronic kidney diseaseGermaine Wong
Centre for Kidney Research and Kids Research Institute, The Children s Hospital at Westmead, Sydney, Australia
Nephrol Dial Transplant 27:3337-44. 2012.... - Gender disparities in the assessment and management of cardiovascular risk in primary care: the AusHEART studyFiona Turnbull
The George Institute for Global Health, University of Sydney, New South Wales, Australia
Eur J Cardiovasc Prev Rehabil 18:498-503. 2011.... - The relationship between proteinuria and coronary risk: a systematic review and meta-analysisVlado Perkovic
The George Institute for International Health, Sydney, New South Wales, Australia
PLoS Med 5:e207. 2008..We therefore undertook a systematic review of published cohort studies aiming to provide a reliable estimate of the strength of association between proteinuria and coronary heart disease... - Decision-making about suitability for kidney transplantation: Results of a national survey of Australian nephrologistsAlan Cass
The George Institute for International Health, Central Clinical School, University of Sydney, and Statewide Renal Services, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
Nephrology (Carlton) 12:299-304. 2007..Given the reduced access to transplantation for Indigenous Australians, the role of patient's ethnicity was of particular interest... - Physical inactivity and chronic kidney disease in Australian adults: the AusDiab studySarah L White
The George Institute for International Health, PO Box M201, Missenden Rd, Camperdown, NSW 2050, Australia Central Clinical School, Faculty of Medicine, University of Sydney, Australia
Nutr Metab Cardiovasc Dis 21:104-12. 2011..We examined the association between leisure-time physical activity and risk of chronic kidney disease in a prospective, population-based cohort of Australians aged ≥ 25 years (AusDiab)... - Community attitudes to deceased organ donation: a focus group studyMichelle J Irving
School of Public Health, The University of Sydney, Sydney, NSW, Australia
Transplantation 93:1064-9. 2012..Despite broad community support for organ donation, there is a chronic shortage of donor organs for transplantation. This study elicited community attitudes on deceased organ donation and the current Australian organ donation system... - Intensities of renal replacement therapy in acute kidney injury: a systematic review and meta-analysisMin Jun
The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
Clin J Am Soc Nephrol 5:956-63. 2010..A systematic review and meta-analysis was undertaken to assess the effect of different intensities of RRT on all-cause mortality and renal recovery in AKI patients... - "All they said was my kidneys were dead": Indigenous Australian patients' understanding of their chronic kidney diseaseKate Anderson
The George Institute for International Health, Sydney, NSW
Med J Aust 189:499-503. 2008..To explore the understanding of both Indigenous and non-Indigenous Australians with end-stage kidney disease (ESKD) about the cause of their disease, and how this understanding could affect patients' engagement with their treatment... - Gaps in cardiovascular disease risk management in Australian general practiceRuth J Webster
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Med J Aust 191:324-9. 2009..To evaluate the management of cardiovascular disease (CVD) risk in Australian general practice... - Effects of fibrates in kidney disease: a systematic review and meta-analysisMin Jun
George Institute For Global Health, The University of Sydney, Sydney, New South Wales, Australia
J Am Coll Cardiol 60:2061-71. 2012..The purpose of this systematic review and meta-analysis was to determine the efficacy and safety of fibrate therapy in the chronic kidney disease (CKD) population... - Community Preferences for the Allocation & Donation of Organs--the PAraDOx StudyKirsten Howard
School of Public Health, University of Sydney, NSW, 2006, Australia
BMC Public Health 11:386. 2011..Reasons for the chronic shortage of deceased organ donations are unclear; there appears to be no lack of 'in principle' public support for organ donation... - Proteinuria and stroke: a meta-analysis of cohort studiesToshiharu Ninomiya
The George Institute for International Health, The University of Sydney, Sydney, Australia
Am J Kidney Dis 53:417-25. 2009..We undertook a meta-analysis of published cohort studies to provide a reliable estimate of the strength of association between proteinuria and risk of stroke... - Effect of lowering blood pressure on cardiovascular events and mortality in patients on dialysis: a systematic review and meta-analysis of randomised controlled trialsHiddo J Lambers Heerspink
George Institute for International Health, University of Sydney, Sydney, Australia
Lancet 373:1009-15. 2009..We did a systematic review and meta-analysis to assess the effect of blood pressure lowering in patients on dialysis... - Systematic review: sodium bicarbonate treatment regimens for the prevention of contrast-induced nephropathySophia Zoungas
University of Sydney, Sydney, Australia
Ann Intern Med 151:631-8. 2009..Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN)... - Cyclosporine withdrawal improves long-term graft survival in renal transplantationMartin Gallagher
Renal Division, The George Institute for International Health, Camperdown, NSW, Australia
Transplantation 87:1877-83. 2009..Cyclosporine has been central to immunosuppressive regimens throughout this period but its effect on long-term transplant outcomes remains unclear... - Rationing scarce organs for transplantation: healthcare provider perspectives on wait-listing and organ allocationAllison Tong
Sydney School of Public Health, The University of Sydney, Sydney, NSW, Australia Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW, Australia
Clin Transplant 27:60-71. 2013..Ongoing engagement with stakeholders is needed to enhance transparency, a reasonable balance between efficiency and equity, and avoid discrimination against specific populations... - The use of psychosocial criteria in Australian patient selection guidelines for kidney transplantationKate Anderson
The George Institute, University of Sydney, Sydney, NSW, Australia
Soc Sci Med 64:2107-14. 2007..The priority given to such criteria in transplant guidelines requires attention and debate... - Community preferences for the allocation of solid organs for transplantation: a systematic reviewAllison Tong
Centre for Kidney Research, The Children s Hospital at Westmead, Sydney, NSW 2145, Australia
Transplantation 89:796-805. 2010..This systematic review aimed to ascertain community preferences for organ allocation and the principles underpinning these preferences... - Socioeconomic disadvantage and kidney disease in the United States, Australia, and ThailandSarah L White
George Institute, Sydney, NSW, Australia
Am J Public Health 98:1306-13. 2008..We sought to determine whether an elevated burden of chronic kidney disease is found among disadvantaged groups living in the United States, Australia, and Thailand... - Intensive glucose control improves kidney outcomes in patients with type 2 diabetesVlado Perkovic
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia
Kidney Int 83:517-23. 2013..Thus, improved glucose control will improve major kidney outcomes in patients with type 2 diabetes... - Hydroxyethyl starch or saline for fluid resuscitation in intensive careJohn A Myburgh
Division of Critical Care and Trauma, George Institute For Global Health, Sydney, NSW, Australia
N Engl J Med 367:1901-11. 2012..The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported... - New tools for an old trade: a socio-technical appraisal of how electronic decision support is used by primary care practitionersDavid Peiris
The George Institute for Global Health, Sydney, New South Wales, Australia
Sociol Health Illn 33:1002-18. 2011..While EDS tools show promise in improving health practitioner performance, the socio-technical dimensions of their implementation warrant careful consideration... - Socioeconomic disparities in stroke rates and outcome: pooled analysis of stroke incidence studies in Australia and New ZealandEmma L Heeley
The George Institute for Global Health, Sydney, NSW
Med J Aust 195:10-4. 2011..To assess the influence of area-level socioeconomic status (SES) on incidence and case-fatality rates for stroke... - Intensive glycemic control and renal outcomeMin Jun
Renal and Metabolic Division, The George Institute for Global Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia
Contrib Nephrol 170:196-208. 2011..Until further data are available, an individualized approach to glucose management is recommended in people with reduced glomerular filtration rate... - Is low birth weight an antecedent of CKD in later life? A systematic review of observational studiesSarah L White
The George Institute, Faculty of Medicine, University of Sydney, Sydney, Australia
Am J Kidney Dis 54:248-61. 2009..There has been considerable interest in the hypothesis that low birth weight may be a marker of impaired nephrogenesis and that this is causally related to chronic kidney disease (CKD)... - How can we achieve global equity in provision of renal replacement therapy?Sarah L White
The George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Sydney, NSW, Australia
Bull World Health Organ 86:229-37. 2008..Prevention of end-stage kidney disease, ideally as part of an integrated approach to chronic vascular diseases, must also be a key objective... - Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysisMin Jun
The George Institute for International Health, University of Sydney, Sydney, Australia
Lancet 375:1875-84. 2010..Several clinical trials have reported inconsistent findings for the effect of fibrates on cardiovascular risk. We undertook a systematic review and meta-analysis to investigate the effects of fibrates on major clinical outcomes... - The cost-effectiveness of increasing kidney transplantation and home-based dialysisKirsten Howard
University of Sydney, Australia
Nephrology (Carlton) 14:123-32. 2009..We aimed to quantify these implications for increasing kidney transplantation and improving the rate of home-based dialysis... - Survival of elderly dialysis patients is predicted by both patient and practice characteristicsCeline Foote
Renal and Metabolic Division, The George Institute for Global Health, Sydney, Australia
Nephrol Dial Transplant 27:3581-7. 2012..Improved understanding of contemporary patient and practice factors influencing prognosis may assist decision making for individual patients and their care providers... - Cardiovascular risk perception and evidence--practice gaps in Australian general practice (the AusHEART study)Emma L Heeley
The George Institute for International Health, Sydney, NSW, Australia
Med J Aust 192:254-9. 2010..To examine the perception and management of cardiovascular disease (CVD) risk in Australian primary care... - Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetesToshiharu Ninomiya
George Institute for International Health, University of Sydney, Sydney, NSW, Australia
J Am Soc Nephrol 20:1813-21. 2009..In conclusion, high albuminuria and low eGFR are independent risk factors for cardiovascular and renal events among patients with type 2 diabetes... - "Looking back to my family": Indigenous Australian patients' experience of hemodialysisKate Anderson
The George Institute for Global Health, Sydney, NSW, Australia
BMC Nephrol 13:114. 2012..Understanding how the demands of dialysis impact on, and are impacted by, the lives of Indigenous patients may provide important insight into treatment pathways and decision-making... - Outcomes of extended-hours hemodialysis performed predominantly at homeMin Jun
George Institute For Global Health, The University of Sydney, Sydney, NSW, Australia
Am J Kidney Dis 61:247-53. 2013..We aimed to describe the outcomes associated with patients starting extended-hours hemodialysis and assess for risk factors for these outcomes... - Cardiovascular disease risk management for Aboriginal and Torres Strait Islander peoples in primary health care settings: findings from the Kanyini AuditDavid P Peiris
The George Institute for International Health, University of Sydney, Sydney, NSW, Australia
Med J Aust 191:304-9. 2009..To describe cardiovascular disease (CVD) risk management in Indigenous primary health care... - Blood pressure is a major risk factor for renal death: an analysis of 560 352 participants from the Asia-Pacific regionConall M O'Seaghdha
George Institute for International Health, Royal Prince Alfred Hospital, Missenden Road, Camperdown, Sydney, New South Wales 2050, Australia
Hypertension 54:509-15. 2009..10). The results were similar for cohorts in Asia and Australia. These results suggest that primary prevention strategies for renal disease should focus on individuals with elevated blood pressure, diabetes mellitus, and dyslipidemia... - Barriers to access by Indigenous Australians to kidney transplantation: the IMPAKT studyAlan Cass
The George Institute for International Health, Sydney, Australia
Nephrology (Carlton) 9:S144-6. 2004..It will systematically examine each of the steps a new dialysis patient must negotiate in order to receive a transplant. Each of these steps can become a barrier... - Building better systems of care for Aboriginal and Torres Strait Islander people: findings from the Kanyini health systems assessmentDavid Peiris
The George Institute for Global Health, University of Sydney, Sydney, Australia
BMC Health Serv Res 12:369. 2012..In this qualitative study we explored Aboriginal Medical Service (AMS) staff views on factors needed to improve chronic care systems and assessed their relevance to the new policy environment... - Limited knowledge of kidney disease in a survey of AusDiab study participantsSarah L White
Renal Division, The George Institute, Sydney, NSW, Australia
Med J Aust 188:204-8. 2008..To explore awareness of the causes of kidney disease and recollection of kidney function testing in a cohort of Australian adults... - The RENAL (Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy) study: statistical analysis planSimon Finfer
The George Institute for International Health, Sydney, NSW
Crit Care Resusc 11:58-66. 2009..The Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study is the largest interventional trial ever conducted in patients with acute renal failure... - Chronic kidney disease, cardiovascular events, and the effects of perindopril-based blood pressure lowering: data from the PROGRESS studyVlado Perkovic
George Institute for International Health, PO Box M201, Sydney, Australia, 2050
J Am Soc Nephrol 18:2766-72. 2007..In conclusion, kidney function should be considered when determining the need for blood pressure lowering therapy in patients with cerebrovascular disease...