Research Topics
Species | Christine F CarsonSummaryAffiliation: University of Western Australia Country: Australia Publications
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Detail Information
Publications
Safety, efficacy and provenance of tea tree (Melaleuca alternifolia) oilC F Carson
Department of Microbiology, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands WA 6009, Australia
Contact Dermatitis 45:65-7. 2001..The identity, sources and composition of tea tree (Melaleuca alternifolia) oil are discussed, and earlier errors in the literature indicated. Reports of both therapeutic and allergenic effects are reviewed...- Use of deception to achieve double-blinding in a clinical trial of Melaleuca alternifolia (tea tree) oil for the treatment of recurrent herpes labialisChristine F Carson
Microbiology and Immunology Discipline, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, Australia
Contemp Clin Trials 29:9-12. 2008..Among the volunteers that were not treated, the P-value was 0.083. This study showed that the ethical use of deception may provide effective blinding in challenging circumstances... 
Mechanism of action of Melaleuca alternifolia (tea tree) oil on Staphylococcus aureus determined by time-kill, lysis, leakage, and salt tolerance assays and electron microscopyChristine F Carson
Department of Microbiology, The University of Western Australia, Crawley
Antimicrob Agents Chemother 46:1914-20. 2002....- Effects of Melaleuca alternifolia (tea tree) essential oil and the major monoterpene component terpinen-4-ol on the development of single- and multistep antibiotic resistance and antimicrobial susceptibilityKatherine A Hammer
Discipline of Microbiology and Immunology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, Western Australia 6009, Australia
Antimicrob Agents Chemother 56:909-15. 2012..Overall, these data indicate that tea tree oil and terpinen-4-ol have little impact on the development of antimicrobial resistance and susceptibility... 
Frequencies of resistance to Melaleuca alternifolia (tea tree) oil and rifampicin in Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalisKatherine A Hammer
Discipline of Microbiology and Immunology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA, Australia
Int J Antimicrob Agents 32:170-3. 2008..aureus mutator strains, which had slightly higher frequencies. These data suggest that Gram-positive organisms such as Staphylococcus and Enterococcus spp. have very low frequencies of resistance to tea tree oil...- Role of the MexAB-OprM efflux pump of Pseudomonas aeruginosa in tolerance to tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and alpha-terpineolChelsea J Papadopoulos
Discipline of Microbiology and Immunology M502, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia
Appl Environ Microbiol 74:1932-5. 2008..These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols... - Susceptibility of pseudomonads to Melaleuca alternifolia (tea tree) oil and componentsChelsea J Papadopoulos
Microbiology and Immunology Discipline, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia 35 Stirling Highway, Crawley, Western Australia 6009, Australia
J Antimicrob Chemother 58:449-51. 2006.... - Tolerance of Pseudomonas aeruginosa to Melaleuca alternifolia (tea tree) oil is associated with the outer membrane and energy-dependent cellular processesChelsea J Longbottom
Microbiology Discipline M502, School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009
J Antimicrob Chemother 54:386-92. 2004..The mechanism(s) by which Pseudomonas aeruginosa NCTC 10662 maintains a decreased susceptibility to tea tree oil and components was investigated... - Antimicrobial and anti-inflammatory activity of five Taxandria fragrans oils in vitroKatherine A Hammer
Discipline of Microbiology and Immunology, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, WA, Australia
Microbiol Immunol 52:522-30. 2008..In conclusion, T. fragrans oil showed both antimicrobial and anti-inflammatory activity in vitro, however, the clinical relevance of this remains to be determined... - Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-olS J Greay
Discipline of Microbiology and Immunology M502, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
Cancer Chemother Pharmacol 65:877-88. 2010..To examine the in vitro anticancer activity of Melaleuca alternifolia (tea tree) oil (TTO), and its major active terpene component, terpinen-4-ol, against two aggressive murine tumour cell lines, AE17 mesothelioma and B16 melanoma... - Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal propertiesC F Carson
Microbiology and Immunology (M502, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009, Australia
Clin Microbiol Rev 19:50-62. 2006..Specific mechanisms of antimicrobial and anti-inflammatory action are reviewed, and the toxicity of the oil is briefly discussed... - A review of the toxicity of Melaleuca alternifolia (tea tree) oilK A Hammer
Microbiology and Immunology M502, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Hwy, Crawley, WA 6009, Australia
Food Chem Toxicol 44:616-25. 2006..The limited ecotoxicity data available indicate that TTO is toxic to some insect species but more studies are required... - Effectiveness of hand-cleansing formulations containing tea tree oil assessed ex vivo on human skin and in vivo with volunteers using European standard EN 1499S Messager
Discipline of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
J Hosp Infect 59:220-8. 2005..TTO in Tween 80 and in formulations met the European in-vivo method requirements... - In vitro susceptibility of Malassezia furfur to the essential oil of Melaleuca alternifoliaK A Hammer
Department of Microbiology, University of Western Australia, Nedlands
J Med Vet Mycol 35:375-7. 1997..The minimum inhibitory concentration for 90% of isolates was 0.25% by agar dilution and 0.12% by broth dilution. These data indicate that tea tree oil may be useful in the treatment of skin conditions involving M. furfur... - Melaleuca alternifolia (tea tree) oil inhibits germ tube formation by Candida albicansK A Hammer
Department of Microbiology, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands
Med Mycol 38:355-62. 2000..25% differed significantly from control cells at later time points (P < 0.01). GTF by C. albicans is affected by the presence of, or pre-exposure to, sub-inhibitory concentrations of TTO. This may have therapeutic implications... - Antifungal effects of Melaleuca alternifolia (tea tree) oil and its components on Candida albicans, Candida glabrata and Saccharomyces cerevisiaeK A Hammer
Microbiology Discipline, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Hwy, Crawley
J Antimicrob Chemother 53:1081-5. 2004..The aim of this study was to investigate the mechanism of action of tea tree oil and its components against Candida albicans, Candida glabrata and Saccharomyces cerevisiae... - Susceptibility of oral bacteria to Melaleuca alternifolia (tea tree) oil in vitroK A Hammer
Discipline of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, Crawley, Western Australia, Australia
Oral Microbiol Immunol 18:389-92. 2003..These studies indicate that a range of oral bacteria are susceptible to tea tree oil, suggesting that tea tree oil may be of use in oral healthcare products and in the maintenance of oral hygiene... - Antifungal activity of the components of Melaleuca alternifolia (tea tree) oilK A Hammer
Discipline of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, Crawley, WA, Australia
J Appl Microbiol 95:853-60. 2003..To investigate the in vitro antifungal activity of the components of Melaleuca alternifolia (tea tree) oil... - Influence of organic matter, cations and surfactants on the antimicrobial activity of Melaleuca alternifolia (tea tree) oil in vitroK A Hammer
Department of Microbiology, University of Western Australia, Nedlands, Western Australia
J Appl Microbiol 86:446-52. 1999..In conclusion, organic matter and surfactants compromise the antimicrobial activity of tea tree oil, although these effects vary between organisms... - In vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes and other filamentous fungiK A Hammer
Department of Microbiology, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia
J Antimicrob Chemother 50:195-9. 2002..These data demonstrate that tea tree oil has both inhibitory and fungicidal activity... - Antimicrobial activity of essential oils and other plant extractsK A Hammer
Department of Microbiology, The University of Western Australia, Nedlands, Western Australia
J Appl Microbiol 86:985-90. 1999..03% (v/v) thyme oil against C. albicans and E. coli and 0.008% (v/v) vetiver oil against Staph. aureus. These results support the notion that plant essential oils and extracts may have a role as pharmaceuticals and preservatives... - Prevalence of delayed hypersensitivity to the European standard series in a self-selected populationJ E Greig
Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Australia
Australas J Dermatol 41:86-9. 2000.... - In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca alternifolia (tea tree) oil against Malassezia speciesK A Hammer
Department of Microbiology, The University of Western Australia, Nedlands, Australia
Antimicrob Agents Chemother 44:467-9. 2000..M. furfur was the least susceptible species. M. sympodialis, M. slooffiae, M. globosa, and M. obtusa showed similar susceptibilities to the four agents... - Candida albicans adhesion to human epithelial cells and polystyrene and formation of biofilm is reduced by sub-inhibitory Melaleuca alternifolia (tea tree) essential oilAurelia N Sudjana
Discipline of Microbiology and Immunology M502, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, Crawley, Western Australia, Australia
Med Mycol 50:863-70. 2012..These data demonstrate that sub-inhibitory TTO reduces the adhesion of C. albicans to both human cells and polystyrene, inhibits biofilm formation and decreases cell surface hydrophobicity... - Inhibition of established subcutaneous murine tumour growth with topical Melaleuca alternifolia (tea tree) oilSara J Greay
Discipline of Microbiology and Immunology M502, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
Cancer Chemother Pharmacol 66:1095-102. 2010..Here, we show for the first time that topical Melaleuca alternifolia (tea tree) oil (TTO), abundant in terpenes, has in vivo antitumour activity... - Assessment of the antibacterial activity of tea tree oil using the European EN 1276 and EN 12054 standard suspension testsS Messager
Discipline of Microbiology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
J Hosp Infect 59:113-25. 2005..The formulations used in this study are now being tested using a novel ex vivo method as well as the in vivo European standard handwashing method EN 1499... - Non-antibiotic therapies for infectious diseasesChristine F Carson
Department of Microbiology, The University of Western Australia, Crawley, Western Australia
Commun Dis Intell 27:S143-6. 2003..Many infections may prove amenable to safe and effective treatment with non-antibiotics...