Jared M Campbell
Affiliation: University of Adelaide
Campbell J, Lane M, Vassiliev I, Nottle M. Use of insulin to increase epiblast cell number: towards a new approach for improving ESC isolation from human embryos. Biomed Res Int. 2013;2013:150901 pubmed publisher
..These findings suggest that culture with insulin may provide a strategy to improve the efficiency with which hESCs are derived from embryos donated at the cleavage stage. ..
Campbell J, Lane M, Owens J, Bakos H. Paternal obesity negatively affects male fertility and assisted reproduction outcomes: a systematic review and meta-analysis. Reprod Biomed Online. 2015;31:593-604 pubmed publisher
..Furthermore, it may be informative to incorporate DNA fragmentation analysis and MMP assessment into semen testing, especially for obese men whose results suggest they should have normal fertility. ..
Campbell J, Bateman E, Stephenson M, Bowen J, Keefe D, Peters M. Methotrexate-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses. Cancer Chemother Pharmacol. 2016;78:27-39 pubmed publisher
Campbell J, Nottle M, Vassiliev I, Mitchell M, Lane M. Insulin increases epiblast cell number of in vitro cultured mouse embryos via the PI3K/GSK3/p53 pathway. Stem Cells Dev. 2012;21:2430-41 pubmed publisher
..Furthermore, we suggest that the inclusion of insulin in culture media could be used as a strategy for increasing the efficiency with which the ESC lines can be derived from cultured embryos...
Campbell J, O Callaghan M, Raymond E, Vincent A, Beckmann K, Roder D, et al
. Tools for Predicting Clinical and Patient-reported Outcomes in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy: A Systematic Review of Prognostic Accuracy and Validity. Clin Genitourin Cancer. 2017;15:629-634.e8 pubmed publisher
..A strong need exists for primary studies that derive and validate tools for the prediction of PROMs in patients undergoing ADT under any circumstance because these are currently absent from the literature. ..
Campbell J, Raymond E, O Callaghan M, Vincent A, Beckmann K, Roder D, et al
. Optimum Tools for Predicting Clinical Outcomes in Prostate Cancer Patients Undergoing Radical Prostatectomy: A Systematic Review of Prognostic Accuracy and Validity. Clin Genitourin Cancer. 2017;15:e827-e834 pubmed publisher
..Use of these tools should help clinicians deliver accurate, evidence-based counseling to patients undergoing prostatectomy. ..
Campbell J, Adanichkin N, Kurmis R, Munn Z. Intensive insulin therapy, insulin sensitisers and insulin secretagogues for burns: A systematic review of effectiveness and safety. Burns. 2017;: pubmed publisher
..These findings support recommendations that moderate insulin administration (130-150mg/dL) is the prudent approach in burn patients. The evidence is relatively sparse and further research is warranted...