- Campbell D. The kallikrein-kinin system in humans. Clin Exp Pharmacol Physiol. 2001;28:1060-5 pubmed..8. Measurement of individual bradykinin and kallidin peptides and their metabolites gives important information about the operation of the plasma and tissue KKS and their role in physiology and disease states. ..
- Campbell D. Towards understanding the kallikrein-kinin system: insights from measurement of kinin peptides. Braz J Med Biol Res. 2000;33:665-77 pubmed..Measurement of the levels of individual kinin peptides has given important information about the operation of the kallikrein-kinin system and its role in physiology and disease states. ..
- Campbell D, Alexiou T, Xiao H, Fuchs S, McKinley M, Corvol P, et al. Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice. Hypertension. 2004;43:854-9 pubmed..These studies demonstrate that ACE is the predominant pathway of angiotensin II formation in blood and tissues of mice and plays a major role in bradykinin (1-9) metabolism in blood and, to a lesser extent, in kidney and heart. ..
- Campbell D, Dixon B, Kladis A, Kemme M, Santamaria J. Activation of the kallikrein-kinin system by cardiopulmonary bypass in humans. Am J Physiol Regul Integr Comp Physiol. 2001;281:R1059-70 pubmed..Aprotinin administration prevented activation of the KKS. The changes in circulating kinin and kallikrein levels indicate activation of both the plasma and tissue KKS during activation of the contact system by CPB...