David Burke

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. pmc Threshold behaviour of human axons explored using subthreshold perturbations to membrane potential
    David Burke
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    J Physiol 587:491-504. 2009
  2. ncbi request reprint Unit identification, sampling bias and technical issues in microneurographic recordings from muscle spindle afferents
    D Burke
    Prince of Wales Medical Research Institute, Randwick, NSW, Australia
    J Neurosci Methods 74:137-44. 1997
  3. ncbi request reprint Quantitative description of the voltage dependence of axonal excitability in human cutaneous afferents
    D Burke
    Department of Neurology, Prince of Wales Hospital and Prince of Wales Medical Research Institute, Randwick, Sydney, Australia
    Brain 121:1975-83. 1998
  4. ncbi request reprint The effects of a volatile anaesthetic on the excitability of human corticospinal axons
    D Burke
    Departments of Clinical Neurophysiology, Anaesthesia and Intensive Care, and Orthopaedics, Prince of Wales Hospital, Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Brain 123:992-1000. 2000
  5. ncbi request reprint Strength-duration properties and their voltage dependence as measures of a threshold conductance at the node of Ranvier of single motor axons
    I Mogyoros
    Department of Neurology, Prince of Wales Hospital and Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Muscle Nerve 23:1719-26. 2000
  6. ncbi request reprint Excitability of human axons
    D Burke
    Department of Neurology, Prince of Wales Hospital and Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney, N S W, Australia
    Clin Neurophysiol 112:1575-85. 2001
  7. ncbi request reprint Effects of activity on axonal excitability: implications for motor control studies
    David Burke
    Spinal Injuries Research Centre, Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Adv Exp Med Biol 508:33-7. 2002
  8. pmc Excitability of human muscle afferents studied using threshold tracking of the H reflex
    Cindy S Y Lin
    Prince of Wales Medical Research Institute, University of New South Wales, and College of Health Sciences, University of Sydney, Sydney, Australia
    J Physiol 545:661-9. 2002
  9. ncbi request reprint Inflections in threshold electrotonus to depolarizing currents in sensory axons
    David Burke
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, University of Sydney, Sydney, NSW 2006, Australia
    Muscle Nerve 36:849-52. 2007
  10. pmc Properties of low-threshold motor axons in the human median nerve
    Louise Trevillion
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    J Physiol 588:2503-15. 2010

Detail Information

Publications63

  1. pmc Threshold behaviour of human axons explored using subthreshold perturbations to membrane potential
    David Burke
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    J Physiol 587:491-504. 2009
    ..By extrapolation, we suggest that, when human axons discharge, nodal slow K+ currents will be activated sufficiently early to contribute to the early changes in excitability following the action potential...
  2. ncbi request reprint Unit identification, sampling bias and technical issues in microneurographic recordings from muscle spindle afferents
    D Burke
    Prince of Wales Medical Research Institute, Randwick, NSW, Australia
    J Neurosci Methods 74:137-44. 1997
    ....
  3. ncbi request reprint Quantitative description of the voltage dependence of axonal excitability in human cutaneous afferents
    D Burke
    Department of Neurology, Prince of Wales Hospital and Prince of Wales Medical Research Institute, Randwick, Sydney, Australia
    Brain 121:1975-83. 1998
    ....
  4. ncbi request reprint The effects of a volatile anaesthetic on the excitability of human corticospinal axons
    D Burke
    Departments of Clinical Neurophysiology, Anaesthesia and Intensive Care, and Orthopaedics, Prince of Wales Hospital, Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Brain 123:992-1000. 2000
    ..It is suggested that the increase in threshold produced by sevoflurane is due to depression of Na(+) currents at the nodes of Ranvier of corticospinal axons...
  5. ncbi request reprint Strength-duration properties and their voltage dependence as measures of a threshold conductance at the node of Ranvier of single motor axons
    I Mogyoros
    Department of Neurology, Prince of Wales Hospital and Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Muscle Nerve 23:1719-26. 2000
    ..There is a reciprocal relationship between tau(SD) and rheobase for single motor units at different membrane potentials, and this relationship may allow changes in tau(SD) due to depolarization and demyelination to be differentiated...
  6. ncbi request reprint Excitability of human axons
    D Burke
    Department of Neurology, Prince of Wales Hospital and Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney, N S W, Australia
    Clin Neurophysiol 112:1575-85. 2001
    ..Each of these measurements depends on membrane potential and on other biophysical properties of the axons. Together they can provide new information about the pathophysiology underlying abnormalities in excitability in neuropathy...
  7. ncbi request reprint Effects of activity on axonal excitability: implications for motor control studies
    David Burke
    Spinal Injuries Research Centre, Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Adv Exp Med Biol 508:33-7. 2002
    ..These data need to be considered when interpreting human reflex studies...
  8. pmc Excitability of human muscle afferents studied using threshold tracking of the H reflex
    Cindy S Y Lin
    Prince of Wales Medical Research Institute, University of New South Wales, and College of Health Sciences, University of Sydney, Sydney, Australia
    J Physiol 545:661-9. 2002
    ..Finally, the difference in latent addition suggests that the longer tau(SD) of the soleus H reflex may indeed be due to greater activity of a persistent Na(+) conductance on Ia afferents than on soleus alpha motor axons...
  9. ncbi request reprint Inflections in threshold electrotonus to depolarizing currents in sensory axons
    David Burke
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, University of Sydney, Sydney, NSW 2006, Australia
    Muscle Nerve 36:849-52. 2007
    ..When large, the notch can distort subsequent phases of threshold electrotonus and could complicate quantitative measurements and modeling studies...
  10. pmc Properties of low-threshold motor axons in the human median nerve
    Louise Trevillion
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    J Physiol 588:2503-15. 2010
    ..We suggest that the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel(s) expressed on human motor axons may be active at rest and contribute to resting membrane potential...
  11. doi request reprint Different mechanisms underlying changes in excitability of peripheral nerve sensory and motor axons in multiple sclerosis
    Karl Ng
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, NSW, Australia
    Muscle Nerve 47:53-60. 2013
    ..Motor excitability studies have suggested upregulation of slow K+ currents, probably secondary to altered motoneuron properties resulting from the central lesion. This study concentrates on sensory axons...
  12. doi request reprint Pathophysiology of HNPP explored using axonal excitability
    Stacey K Jankelowitz
    Department of Neurology, Institute of Clinical Neuroscience, Royal Prince Alfred Hospital, and University of Sydney, Level 2, Medical Foundation Building, 92 Parramatta Road, Camperdown, Sydney, NSW 2050, Australia
    J Neurol Neurosurg Psychiatry 84:806-12. 2013
    ..Hereditary liability to pressure palsies (HNPP) is an autosomal dominant disorder of myelination resulting in susceptibility to pressure palsies from compression or stretching of peripheral nerves...
  13. pmc Responses of human sensory and motor axons to the release of ischaemia and to hyperpolarizing currents
    Cindy S Y Lin
    Prince of Wales Medical Research Institute, University of New South Wales, Australia
    J Physiol 541:1025-39. 2002
    ....
  14. ncbi request reprint Postactivation depression of the soleus H reflex measured using threshold tracking
    Penelope A McNulty
    Institute of Clinical Neurosciences, The University of Sydney, Royal Prince Alfred Hospital, Sydney, Australia
    J Neurophysiol 100:3275-84. 2008
    ..Using threshold tracking, HD was maximal at lower frequencies than previously emphasized, probably because HD is greater the larger the test H reflex. This would reinforce the greater sensitivity of small motoneurons to reflex inputs...
  15. doi request reprint Axonal excitability in the forearm: normal data and differences along the median nerve
    S K Jankelowitz
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and University of Sydney, Medical Foundation Building K 25, Sydney, NSW 2006, Australia
    Clin Neurophysiol 120:167-73. 2009
    ..The differences in measures of excitability due to different sites of stimulation or a different test muscle group was also determined...
  16. ncbi request reprint Motoneuron excitability and the F wave
    M Geraldine Espiritu
    Department of Clinical Neurophysiology, Prince of Wales Hospital, and Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
    Muscle Nerve 27:720-7. 2003
    ..The findings also suggest that F waves provide a flawed measure of the excitability of the motoneuron pool...
  17. ncbi request reprint Abnormalities of axonal excitability are not generalized in early multifocal motor neuropathy
    Cecilia Cappelen-Smith
    Department of Clinical Neurophysiology, Prince of Wales Hospital and Prince of Wales Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney, New South Wales 2031, Australia
    Muscle Nerve 26:769-76. 2002
    ..Again no differences were detected. This study provides no evidence for a generalized subclinical abnormality in MMN, at least when disease duration is less than 6 years...
  18. ncbi request reprint Acute tetrodotoxin-induced neurotoxicity after ingestion of puffer fish
    Matthew C Kiernan
    Prince of Wales Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney NSW 2031, Australia
    Ann Neurol 57:339-48. 2005
    ..It demonstrates the ability of noninvasive nerve excitability studies to detect Na(+) channel blockade in vivo and also the utility of mathematical modeling to aid interpretation of altered excitability properties in disease...
  19. pmc The voltage dependence of I(h) in human myelinated axons
    James Howells
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    J Physiol 590:1625-40. 2012
    ....
  20. ncbi request reprint Activity-dependent hyperpolarization and impulse conduction in motor axons in patients with carpal tunnel syndrome
    Cecilia Cappelen-Smith
    Prince of Wales Medical Research Institute, University of New South Wales and Department of Clinical Neurophysiology, Prince of Wales Hospital, Sydney, Australia
    Brain 126:1001-8. 2003
    ..These studies support the view that demyelination may not be a critical factor in the slowing of impulse conduction in mild to moderate carpal tunnel syndrome...
  21. pmc Excitability and the safety margin in human axons during hyperthermia
    James Howells
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and the University of Sydney, Sydney, Australia
    J Physiol 591:3063-80. 2013
    ..The further hyperpolarization of the activation of Ih would limit its ability to counter the hyperpolarization produced by activity, thereby allowing conduction block to occur during hyperthermia...
  22. pmc Differences in activity-dependent hyperpolarization in human sensory and motor axons
    Matthew C Kiernan
    Prince of Wales Medical Research Institute, University of New South Wales and Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, Australia
    J Physiol 558:341-9. 2004
    ....
  23. ncbi request reprint Mutation in the Na+ channel subunit SCN1B produces paradoxical changes in peripheral nerve excitability
    Matthew C Kiernan
    Prince of Wales Medical Research Institute, Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
    Brain 128:1841-6. 2005
    ....
  24. pmc Outwardly rectifying deflections in threshold electrotonus due to K+ conductances
    Louise Trevillion
    University of Sydney, Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia
    J Physiol 580:685-96. 2007
    ..This may also explain the notch in demyelinating diseases...
  25. doi request reprint Up-regulation of slow K(+) channels in peripheral motor axons: a transcriptional channelopathy in multiple sclerosis
    Karl Ng
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and the University of Sydney, Sydney, NSW, Australia
    Brain 131:3062-71. 2008
    ..This study thus provides evidence for plasticity in motoneuronal properties at a molecular level, the first such evidence for intact human subjects...
  26. ncbi request reprint Effects of voluntary activity on the excitability of motor axons in the peroneal nerve
    Satoshi Kuwabara
    Prince of Wales Medical Research Institute, University of New South Wales, Barker Street, Randwick, Sydney, NSW 2031, Australia
    Muscle Nerve 25:176-84. 2002
    ..Third, TA is probably not optimal for testing for activity-dependent conduction block...
  27. pmc In vivo loss of slow potassium channel activity in individuals with benign familial neonatal epilepsy in remission
    Susan E Tomlinson
    Department of Neurology, Royal Prince Alfred Hospital, University of Sydney, NSW, Australia
    Brain 135:3144-52. 2012
    ..We conclude that subclinical dysfunction of K(v)7.2 in peripheral axons can be reliably detected non-invasively in adulthood. Related alterations in neuronal excitability may contribute to epilepsy associated with KCNQ2 mutations...
  28. doi request reprint Pathophysiology of spasticity in stroke
    David Burke
    Department of Neurology, Royal Prince Alfred Hospital and University of Sydney, Australia
    Neurology 80:S20-6. 2013
    ..Managing a patient with impairment after a stroke requires therapy tailored to that particular patient because the mechanisms contributing to the disability experienced by one patient may differ from those affecting another...
  29. pmc Excitability changes in human peripheral nerve axons in a paradigm mimicking paired-pulse transcranial magnetic stimulation
    Jane H L Chan
    Prince of Wales Medical Research Institute, University of New South Wales and College of Health Sciences, University of Sydney, Sydney, Australia
    J Physiol 542:951-61. 2002
    ..This study supports the view that changes in excitability of the stimulated axons should be considered before synaptic mechanisms are invoked in the interpretation of findings from paired-pulse TMS studies...
  30. ncbi request reprint Conduction block during and after ischaemia in chronic inflammatory demyelinating polyneuropathy
    Cecilia Cappelen-Smith
    Prince of Wales Medical Research Institute, University of New South Wales and Department of Clinical Neurophysiology, The Prince of Wales Hospital, Sydney, NSW, Australia
    Brain 125:1850-8. 2002
    ....
  31. doi request reprint The stability of M(max) and H (max) amplitude over time
    Penelope A McNulty
    Neuroscience Research Australia, University of New South Wales, Barker Street, Randwick, Sydney, NSW 2031, Australia
    Exp Brain Res 218:601-7. 2012
    ..On average, there was no change in the H(max)/M(max) ratio over time. While both M(max) and H(max) may change in response to many factors, these results suggest that, typically, time is not one of them...
  32. ncbi request reprint Conduction block in demyelinated axons precipitated by normally innocuous physiological processes
    David Burke
    Office of Research and Development, College of Health Sciences, University of Sydney, Sydney, NSW 2006, Australia
    Suppl Clin Neurophysiol 57:191-4. 2004
  33. ncbi request reprint Axonal excitability in viral polyneuropathy and nucleoside neuropathy in HIV patients
    Karl Ng
    Royal North Shore Hospital, University of Sydney, Sydney, Australia
    J Neurol Neurosurg Psychiatry 82:978-80. 2011
    ..Confirmation of these findings may allow neurophysiological distinction between these entities...
  34. doi request reprint Axonal hyperpolarization in inclusion-body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD)
    Kishore R Kumar
    Department of Neurology and Clinical Neurophysiology and Kolling Institute of Medical Research, Royal North Shore Hospital, and University of Sydney, NSW, Australia
    Muscle Nerve 44:191-6. 2011
    ..Patients with this disorder may have neuropathic or myopathic features...
  35. ncbi request reprint Changes in measures of motor axon excitability with age
    S K Jankelowitz
    Institute of Clinical Neurosciences, University of Sydney and Royal Prince Alfred Hospital, Sydney, Australia
    Clin Neurophysiol 118:1397-404. 2007
    ..Protocols have been validated for sensory and motor axons, but there are limited data on the changes in the excitability of motor axons with age. This study aimed to determine such changes from the third to the eighth decades...
  36. pmc Self-sustained motor activity triggered by interlimb reflexes in chronic spinal cord injury, evidence of functional ascending propriospinal pathways
    Penelope A McNulty
    Neuroscience Research Australia and University of New South Wales, Sydney, Australia
    PLoS ONE 8:e72725. 2013
    ..They emphasize the potential for pathways below the level of injury to generate movement, and the role of self-sustained reflex activity in the sequelae of spinal cord injury. ..
  37. doi request reprint Activity-dependent conduction failure: molecular insights
    Susanna B Park
    Prince of Wales Clinical School, University of New South Wales, Sydney, Australia
    J Peripher Nerv Syst 16:159-68. 2011
    ....
  38. doi request reprint Do the motor manifestations of Parkinson disease alter motor axon excitability?
    Stacey K Jankelowitz
    Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia
    Muscle Nerve 45:43-7. 2012
    ..Given the motor neuron changes in the presence of rigidity and tremor in Parkinson disease, we examine whether there are also changes in motor axon excitability...
  39. pmc Sodium channel function and the excitability of human cutaneous afferents during ischaemia
    Cindy S Y Lin
    Prince of Wales Medical Research Institute, University of New South Wales and Department of Neurology, The Prince of Wales Hospital, Sydney, Australia
    J Physiol 538:435-46. 2002
    ..Without these processes, the ischaemic change in threshold would be much greater than that actually recorded, probably sufficient to produce prominent ectopic impulse activity...
  40. ncbi request reprint Augmentation of the contraction force of human thenar muscles by and during brief discharge trains
    James Howells
    Institute of Clinical Neurosciences, University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW 2006, Australia
    Muscle Nerve 33:384-92. 2006
    ..Discharge rates of 15-20 HZ appear to be optimal for force generation by APB during steady contractions...
  41. doi request reprint The effects of alterations in conditioning stimulus intensity on short interval intracortical inhibition
    Steve Vucic
    Department of Neurology, Westmead Hospital and Western Clinical School, University of Sydney, Australia
    Brain Res 1273:39-47. 2009
    ..8%]. Facilitation was evident at 1 ms. The findings from the present study suggest that inhibitory circuits with different thresholds underlie the phases of SICI, with synaptic mechanisms also critical to the development of SICI at 1 ms...
  42. ncbi request reprint Fatigue in multiple sclerosis: mechanisms and management
    Steve Vucic
    Department of Neurology, Westmead Hospital and Western Clinical School, University of Sydney, Sydney, NSW, Australia
    Clin Neurophysiol 121:809-17. 2010
    ....
  43. pmc The properties of axons differ according to their function
    David Burke
    Institute of Clinical Neurosciences, University of Sydney and Royal Prince Alfred Hospital, Sydney, New South Wales 2006, Australia
    J Physiol 578:1-2. 2007
  44. ncbi request reprint Corticospinal volleys and compound muscle action potentials produced by repetitive transcranial stimulation during spinal surgery
    Kathleen Bartley
    Department of Clinical Neurophysiology, Prince of Wales and Sydney Children s Hospitals, Sydney, Australia
    Clin Neurophysiol 113:78-90. 2002
    ....
  45. ncbi request reprint Forces consistent with plateau-like behaviour of spinal neurons evoked in patients with spinal cord injuries
    P Nickolls
    Spinal Injuries Research Center, Prince of Wales Medical Research Institute and University of New South Wales, Australia
    Brain 127:660-70. 2004
    ..These contractions are consistent with the activation of plateau potentials in spinal neurons and, if so, plateau potentials may contribute to a patient's clinical manifestations...
  46. ncbi request reprint Axonal excitability in X-linked dominant Charcot Marie Tooth disease
    Christina Liang
    Department of Neurology and Clinical Neurophysiology, Royal North Shore Hospital, NSW, Australia The University of Sydney, NSW, Australia
    Clin Neurophysiol 125:1261-9. 2014
    ..We investigated peripheral nerve function in X-linked Charcot-Marie-Tooth disease type 1 (CMTX1), and considered the functional consequences of mutant connexin-32...
  47. ncbi request reprint Riluzole therapy for motor neurone disease: an early Australian experience (1996-2002)
    Margie C Zoing
    Multidisciplinary Motor Neurone Disease Service, Institute of Neurological Sciences, Prince of Wales Hospital, Sydney, New South Wales, Australia
    J Clin Neurosci 13:78-83. 2006
    ..Issues related to patient perceptions of efficacy highlight the need for patients and treating physicians to maintain realistic expectations of riluzole therapy...
  48. doi request reprint HCN Channels: Function and clinical implications
    David Burke
    Sydney, Australia
    Neurology 81:513-4. 2013
    ..In neuropathic pain, the situation is less certain because the action potentials of small nociceptive afferents can only be characterized with microneurography. ..
  49. ncbi request reprint Cytoplasmic body myopathy masquerading as motor neuron disease
    Arun V Krishnan
    Multidisciplinary Motor Neuron Disease Service, Institute of Neurological Sciences, Prince of Wales Hospital, High Street, Randwick, Sydney, NSW 2031, Australia
    Muscle Nerve 30:667-72. 2004
    ..The case highlights a further diagnostic possibility in the assessment of patients with "possible" motor neuron disease. The clinical features of CBM are briefly reviewed...
  50. doi request reprint Potentiating patient participation: the 'Homeward Bound' psychoeducation programme for depression in old age
    Sarah O' Dwyer
    St Vincent s Hospital Psychogeriatrics Mental Health Service, St Vincent s Hospital, Darlinghurst, NSW, Australia
    Australas Psychiatry 20:397-400. 2012
    ..Vincent's Hospital Psychogeriatrics Mental Health Service (SVHMHS) 'Homeward Bound' psychoeducation programme using an education-workbook for older adults with depression and their carers...
  51. ncbi request reprint Clinical neurophysiology of the episodic ataxias: insights into ion channel dysfunction in vivo
    Susan E Tomlinson
    Institute of Clinical Neurosciences, Royal Prince Alfred Hospital and University of Sydney, Sydney, Australia
    Clin Neurophysiol 120:1768-76. 2009
    ..The clinical, genetic and electrophysiological features of EA1 and EA2 are outlined, and a protocol for the assessment of these patients is proposed...
  52. doi request reprint Early intervention for cognitive decline: is there a role for multiple medical or behavioural interventions?
    Sharon L Naismith
    Brain and Mind Research Institute, The George Institute for International Health, University of Sydney, Sydney, New South Wales, Australia
    Early Interv Psychiatry 3:19-27. 2009
    ..Evidence for the beneficial effects of providing relevant interventions is assessed...
  53. pmc Suppression of the H reflex in humans by disynaptic autogenetic inhibitory pathways activated by the test volley
    Véronique Marchand-Pauvert
    Reeducation, Neurophysiologie Clinique UPRES EA 2393, Hopital de la Salpetriere, 75651 Paris Cedex 13, France
    J Physiol 542:963-76. 2002
    ..It is concluded that the size of the H reflex is limited by disynaptic inhibition, and that changes in the excitability of this inhibitory pathway can produce prominent changes in the H reflex...
  54. ncbi request reprint Recent evidence for plateau potentials in human motoneurones
    David F Collins
    Faculty of Physical Education and Recreation, University of Alberta, Edmonton, Canada
    Adv Exp Med Biol 508:227-35. 2002
    ..The extent to which the nervous system uses this as a gain control mechanism to tailor motor output for a given task needs to be further explored...
  55. ncbi request reprint Axonal hyperpolarization associated with acute hypokalemia: multiple excitability measurements as indicators of the membrane potential of human axons
    Satoshi Kuwabara
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Muscle Nerve 26:283-7. 2002
    ..Multiple excitability measurements can be used as a tool to identify changes in membrane potential of human axons...
  56. ncbi request reprint Differences in membrane properties of axonal and demyelinating Guillain-Barré syndromes
    Satoshi Kuwabara
    Department of Neurology, Chiba University School of Medicine, Chiba, Japan
    Ann Neurol 52:180-7. 2002
    ..These results support the view that the predominantly distal targets of immune attack are different for AMAN and AIDP. Possible mechanisms for the reduced safety factor in AMAN are discussed...
  57. ncbi request reprint The refractory period of transmission is impaired in axonal Guillain-Barré syndrome
    Satoshi Kuwabara
    Department of Neurology, Chiba University School of Medicine, 1 8 1 Inohana, Chuo Ku, Chiba 260 8670, Japan
    Muscle Nerve 28:683-9. 2003
    ..In addition to axonal degeneration, the critically but reversibly reduced safety factor is important in the pathophysiology of AMAN, and consistent with the rapid resolution of distal conduction block often seen in AMAN patients...
  58. pmc Task-related changes in propriospinal excitation from hand muscles to human flexor carpi radialis motoneurones
    Caroline Iglesias
    INSERM, U731, Paris, F 75013 France
    J Physiol 582:1361-79. 2007
    ..The resulting more effective background excitation of propriospinal neurones by the peripheral input from hand muscles could contribute to stabilizing the wrist during grip...
  59. pmc Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects
    Stacey K Jankelowitz
    Medical Foundation Building K25, The University of Sydney, NSW 2006, Australia
    J Physiol 581:927-40. 2007
    ..In human subjects studies of motor axon properties may allow insight into processes affecting the motoneuron...
  60. ncbi request reprint Axonal excitability measured by tracking twitch contraction force
    Louise Trevillion
    Institute of Clinical Neurosciences, University of Sydney, NSW 2006, Australia
    Muscle Nerve 30:437-43. 2004
    ..Thus, tracking twitch contraction force is a potentially valuable alternative to tracking the CMAP, but is more complicated and the results need to be interpreted with caution...
  61. pmc After-effects of near-threshold stimulation in single human motor axons
    Hugh Bostock
    Sobell Department of Neurophysiology, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    J Physiol 564:931-40. 2005
    ....
  62. ncbi request reprint Symptoms of thoracic outlet syndrome in women with carpal tunnel syndrome
    David Burke
    Clin Neurophysiol 117:930-1. 2006
  63. ncbi request reprint Frequency-dependent conduction block in carpal tunnel syndrome
    David Burke
    Muscle Nerve 33:587-8. 2006