H Brodaty

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. doi request reprint Influence of population versus convenience sampling on sample characteristics in studies of cognitive aging
    Henry Brodaty
    Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Electronic address
    Ann Epidemiol 24:63-71. 2014
  2. doi request reprint Mild cognitive impairment in a community sample: the Sydney Memory and Ageing Study
    Henry Brodaty
    Primary Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, New South Wales, Australia
    Alzheimers Dement 9:310-317.e1. 2013
  3. doi request reprint Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia
    Henry Brodaty
    Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia
    Am J Psychiatry 169:946-53. 2012
  4. doi request reprint Neuropsychiatric symptoms in older people with and without cognitive impairment
    Henry Brodaty
    Primary Dementia Collaborative Research Centre, School of Psychiatry, Faculty of Medicine, University of New South Wales, NSW, Australia
    J Alzheimers Dis 31:411-20. 2012
  5. doi request reprint Nonpharmacological management of apathy in dementia: a systematic review
    Henry Brodaty
    Dementia Collaborative Research Centre, Faculty of Medicine, School of Psychiatry, University of New South Wales HB, Randwick, New South Wales, Australia
    Am J Geriatr Psychiatry 20:549-64. 2012
  6. pmc Ageing in general practice (AGP) trial: a cluster randomised trial to examine the effectiveness of peer education on GP diagnostic assessment and management of dementia
    Constance D Pond
    School of Medicine and Population Health, University of Newcastle, Newcastle, Australia 2308
    BMC Fam Pract 13:12. 2012
  7. doi request reprint Dementia time to death: a systematic literature review on survival time and years of life lost in people with dementia
    Henry Brodaty
    Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia
    Int Psychogeriatr 24:1034-45. 2012
  8. pmc Psychometric performance of an assessment scale for strain in nursing care: the M-NCAS
    Leah Kleinman
    MEDTAP International, Inc, 2601 4th Ave, Seattle, WA 98121, USA
    Health Qual Life Outcomes 2:62. 2004
  9. pmc Who pays and who benefits? How different models of shared responsibilities between formal and informal carers influence projections of costs of dementia management
    Victor Vickland
    Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia
    BMC Public Health 11:793. 2011
  10. pmc A systematic review of different models of home and community care services for older persons
    Lee Fay Low
    Dementia Collaborative Research Centre, School of Psychiatry, Faculty of Medicine, AGSM Building, University of NSW, Sydney NSW 2052 Australia
    BMC Health Serv Res 11:93. 2011

Detail Information

Publications131 found, 100 shown here

  1. doi request reprint Influence of population versus convenience sampling on sample characteristics in studies of cognitive aging
    Henry Brodaty
    Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia Electronic address
    Ann Epidemiol 24:63-71. 2014
    ....
  2. doi request reprint Mild cognitive impairment in a community sample: the Sydney Memory and Ageing Study
    Henry Brodaty
    Primary Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, New South Wales, Australia
    Alzheimers Dement 9:310-317.e1. 2013
    ..Mild cognitive impairment (MCI) is associated with an increased dementia risk. This study reports incidence of MCI subtypes, rates of progression to dementia, and stability of MCI classification...
  3. doi request reprint Meta-analysis of nonpharmacological interventions for neuropsychiatric symptoms of dementia
    Henry Brodaty
    Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia
    Am J Psychiatry 169:946-53. 2012
    ..The authors reviewed the effectiveness of community-based nonpharmacological interventions delivered through family caregivers...
  4. doi request reprint Neuropsychiatric symptoms in older people with and without cognitive impairment
    Henry Brodaty
    Primary Dementia Collaborative Research Centre, School of Psychiatry, Faculty of Medicine, University of New South Wales, NSW, Australia
    J Alzheimers Dis 31:411-20. 2012
    ..Overall rates of NPS at baseline were not associated with MCI, dementia, or cognitive decline over two years. Additional follow-up is needed to further examine this association over a longer time course...
  5. doi request reprint Nonpharmacological management of apathy in dementia: a systematic review
    Henry Brodaty
    Dementia Collaborative Research Centre, Faculty of Medicine, School of Psychiatry, University of New South Wales HB, Randwick, New South Wales, Australia
    Am J Geriatr Psychiatry 20:549-64. 2012
    ..This review indicates that therapeutic activities, particularly those provided individually, have the best available evidence for effectiveness in dementia. Recommendations are provided for quality research...
  6. pmc Ageing in general practice (AGP) trial: a cluster randomised trial to examine the effectiveness of peer education on GP diagnostic assessment and management of dementia
    Constance D Pond
    School of Medicine and Population Health, University of Newcastle, Newcastle, Australia 2308
    BMC Fam Pract 13:12. 2012
    ..This trial examines the effectiveness of a peer led dementia educational intervention for GPs...
  7. doi request reprint Dementia time to death: a systematic literature review on survival time and years of life lost in people with dementia
    Henry Brodaty
    Dementia Collaborative Research Centre, University of New South Wales, Sydney, NSW, Australia
    Int Psychogeriatr 24:1034-45. 2012
    ..As well as years of survival, it is useful to consider years of life lost after a diagnosis of dementia...
  8. pmc Psychometric performance of an assessment scale for strain in nursing care: the M-NCAS
    Leah Kleinman
    MEDTAP International, Inc, 2601 4th Ave, Seattle, WA 98121, USA
    Health Qual Life Outcomes 2:62. 2004
    ..Nurses rate items in terms of extent to which the behavior or characteristic is present ("attitude" domain), and extent to which it is a burden ("strain" domain)...
  9. pmc Who pays and who benefits? How different models of shared responsibilities between formal and informal carers influence projections of costs of dementia management
    Victor Vickland
    Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia
    BMC Public Health 11:793. 2011
    ..This study aimed to determine more accurately the future costs of dementia management by taking these factors into consideration...
  10. pmc A systematic review of different models of home and community care services for older persons
    Lee Fay Low
    Dementia Collaborative Research Centre, School of Psychiatry, Faculty of Medicine, AGSM Building, University of NSW, Sydney NSW 2052 Australia
    BMC Health Serv Res 11:93. 2011
    ..The aim of this review is to evaluate the outcomes of case managed, integrated or consumer directed home and community care services for older persons, including those with dementia...
  11. pmc Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial
    Nicola J Gates
    School of Psychiatry, University of New South Wales, and Neuropsychiatric Institute, Prince of Wales Hospital, Randwick NSW 2031, Australia
    BMC Geriatr 11:19. 2011
    ....
  12. ncbi request reprint Age and gender in the phenomenology of depression
    Henry Brodaty
    Academic Dept for Old Age Psychiatry, Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, Sydney, Australia
    Am J Geriatr Psychiatry 13:589-96. 2005
    ..Authors investigated the effects of current age, age at onset, and gender on the phenomenology of depression...
  13. ncbi request reprint Galantamine prolonged-release formulation in the treatment of mild to moderate Alzheimer's disease
    Henry Brodaty
    University of New South Wales, Sydney, Australia
    Dement Geriatr Cogn Disord 20:120-32. 2005
    ....
  14. ncbi request reprint Why caregivers of people with dementia and memory loss don't use services
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Australia
    Int J Geriatr Psychiatry 20:537-46. 2005
    ..To develop a typography of the characteristics of caregivers of community dwelling people with dementia or memory loss who do not use services and empirically investigate the reasons for service non-use...
  15. pmc The effects of counseling spouse caregivers of people with Alzheimer disease taking donepezil and of country of residence on rates of admission to nursing homes and mortality
    Henry Brodaty
    Primary Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, Australia
    Am J Geriatr Psychiatry 17:734-43. 2009
    ..Does psychosocial intervention for caregivers whose spouses with Alzheimer disease (AD) are taking donepezil delay nursing home (NH) placement or death of patients?..
  16. ncbi request reprint Vulnerability to post-traumatic stress disorder and psychological morbidity in aged holocaust survivors
    Henry Brodaty
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, NSW 2031, Australia
    Int J Geriatr Psychiatry 19:968-79. 2004
    ....
  17. ncbi request reprint Characteristics of the GPCOG, a screening tool for cognitive impairment
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Australia
    Int J Geriatr Psychiatry 19:870-4. 2004
    ..Early dementia diagnosis is aided by the use of brief screening tests; scores can be biased by patient and informant characteristics such as age, gender and education...
  18. ncbi request reprint Nursing home staff attitudes towards residents with dementia: strain and satisfaction with work
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Randwick, New South Wales 2031, Australia
    J Adv Nurs 44:583-90. 2003
    ..Workload is highly predictive of the experience of burden and job pressure, while these outcomes vary according to whether staff work full- or part-time...
  19. ncbi request reprint Meta-analysis of psychosocial interventions for caregivers of people with dementia
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Am Geriatr Soc 51:657-64. 2003
    ..To review published reports of interventions for caregivers (CGs) of persons with dementia, excluding respite care, and provide recommendations to clinicians...
  20. ncbi request reprint Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke - the Sydney Stroke Study
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Randwick, Australia
    Psychol Med 35:1707-16. 2005
    ..The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined...
  21. ncbi request reprint Risperidone for psychosis of Alzheimer's disease and mixed dementia: results of a double-blind, placebo-controlled trial
    Henry Brodaty
    Academic Department of Psychogeriatrics, School of Psychiatry, University of New South Wales, Sydney, Australia
    Int J Geriatr Psychiatry 20:1153-7. 2005
    ....
  22. doi request reprint Patients in Australian Memory Clinics: baseline characteristics and predictors of decline at six months
    Henry Brodaty
    Dementia Collaborative Research Centre, School of Psychiatry, University of NSW, Sydney, Australia
    Int Psychogeriatr 23:1086-96. 2011
    ..The Prospective Research In MEmory clinics (PRIME) is a three-year non-prescriptive, observational study identifying and measuring relationships among predictor and outcome variables...
  23. doi request reprint Dementia services in Australia
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Sydney, NSW, Australia
    Int J Geriatr Psychiatry 25:887-995. 2010
    ..To describe dementia services in Australia...
  24. doi request reprint Do people become more apathetic as they grow older? A longitudinal study in healthy individuals
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 22:426-36. 2010
    ..The aim of this study was to determine levels, rates and progression of apathy in healthy older persons and to investigate factors associated with its progression...
  25. pmc Family caregivers of people with dementia
    Henry Brodaty
    Primary Dementia Collaborative Research Centre and School of Psychiatry, University of New South Wales, Sydney, Australia
    Dialogues Clin Neurosci 11:217-28. 2009
    ..Comprehensive management of the patient with dementia includes building a partnership between health professionals and family caregivers, referral to Alzheimer's Associations, and psychosocial interventions where indicated...
  26. ncbi request reprint Rates of depression at 3 and 15 months poststroke and their relationship with cognitive decline: the Sydney Stroke Study
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Randwick, NSW, Australia
    Am J Geriatr Psychiatry 15:477-86. 2007
    ..To investigate the frequency and correlates of depression at 3 and 15 months after stroke...
  27. ncbi request reprint Meaning and measurement of caregiver outcomes
    Henry Brodaty
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, and Primary Dementia Collaborative Research Centre and School of Psychiatry, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 19:363-81. 2007
    ..Measurement of caregiver outcomes should be targeted to likely outcome, and key mediating variables should be measured too. A list of potential instruments and recommendations is provided...
  28. ncbi request reprint A naturalistic study of galantamine for Alzheimer's disease
    Henry Brodaty
    Academic Department for Old Age Psychiatry, School of Psychiatry, University of New South Wales and Prince of Wales Hospital, Randwick, NSW, Australia
    CNS Drugs 20:935-43. 2006
    ..To collect descriptive data on the treatment of Alzheimer's disease with galantamine under naturalistic conditions...
  29. ncbi request reprint What is the best dementia screening instrument for general practitioners to use?
    Henry Brodaty
    Academic Department for Old Age Psychiatry, Euroa Centre, Prince of Wales Hospital, Randwick, Australia
    Am J Geriatr Psychiatry 14:391-400. 2006
    ..The objective of this study was to review existing dementia screening tools with a view to informing and recommending suitable instruments to general practitioners (GPs) based on their performance and practicability for general practice...
  30. ncbi request reprint A randomized placebo-controlled trial of risperidone for the treatment of aggression, agitation, and psychosis of dementia
    Henry Brodaty
    Academic Department for Old Age Psychiatry, School of Psychiatry, University of New South Wales, Sydney, Australia
    J Clin Psychiatry 64:134-43. 2003
    ..This randomized, double-blind, placebo-controlled trial examined the efficacy and safety of risperidone in the treatment of aggression, agitation, and psychosis in elderly nursing-home patients with dementia...
  31. ncbi request reprint Behavioural and psychological symptoms of dementia: a seven-tiered model of service delivery
    Henry Brodaty
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Avoca Street, Randwick, NSW 2031, Australia
    Med J Aust 178:231-4. 2003
    ..Lower-level interventions may prevent the need for the more intensive interventions needed when disturbance becomes more severe...
  32. ncbi request reprint Depression, diagnostic sub-type and death: a 25 year follow-up study
    H Brodaty
    Academic Department of Psychogeriatrics, Prince Henry Hospital, University of New South Wales, Sydney, Australia
    J Affect Disord 46:233-42. 1997
    ....
  33. ncbi request reprint A prospective follow-up study of ECT outcome in older depressed patients
    H Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Affect Disord 60:101-11. 2000
    ..This study examined the relationship between age and outcome of electroconvulsive therapy (ECT)...
  34. ncbi request reprint Perceptions of outcome from electroconvulsive therapy by depressed patients and psychiatrists
    Henry Brodaty
    School of Psychiatry, University of New South Wales, and Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia
    Aust N Z J Psychiatry 37:196-9. 2003
    ....
  35. ncbi request reprint Who cares for the carer? The often forgotten patient
    Henry Brodaty
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, School of Psychiatry, University of New South Wales
    Aust Fam Physician 31:833-6. 2002
    ..Dementia not only affects the patient but also those nearest the patient most notably the carer. It is known that caring for a patient with dementia can adversely affect one's psychological, physical, social and financial health...
  36. ncbi request reprint Schizophrenia with onset after age 50 years. I: Phenomenology and risk factors
    H Brodaty
    School of Psychiatry, University of New South Wales, Sydney
    Br J Psychiatry 175:410-5. 1999
    ..Schizophrenia occurring for the first time in late life may be a distinct entity or part of a continuum...
  37. ncbi request reprint Psychosis, depression and behavioural disturbances in Sydney nursing home residents: prevalence and predictors
    H Brodaty
    School of Psychiatry, University of New South Wales, Australia
    Int J Geriatr Psychiatry 16:504-12. 2001
    ..There is wide variation in the rates of behavioural and psychological symptoms of dementia (BPSD) reported in nursing homes...
  38. ncbi request reprint Early and late onset depression in old age: different aetiologies, same phenomenology
    H Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Affect Disord 66:225-36. 2001
    ..We aimed to compare aetiological factors, phenomenology and cognitive function in older patients with depression by age of onset...
  39. ncbi request reprint The GPCOG: a new screening test for dementia designed for general practice
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Am Geriatr Soc 50:530-4. 2002
    ..To design and test a brief, efficient dementia-screening instrument for use by general practitioners (GPs)...
  40. ncbi request reprint Familial idiopathic basal ganglia calcification (Fahr's disease) without neurological, cognitive and psychiatric symptoms is not linked to the IBGC1 locus on chromosome 14q
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Hum Genet 110:8-14. 2002
    ..We have identified a form of IBGC in which calcification is inherited independently of neurological, cognitive and psychiatric symptoms. This may represent a second locus for this disorder...
  41. doi request reprint The world of dementia beyond 2020
    Henry Brodaty
    Dementia Collaborative Research Centre, School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia
    J Am Geriatr Soc 59:923-7. 2011
    ..This article provides an overview of current achievements and potentials of basic and clinical research that might affect the development of dementia prevalence and care within the near future...
  42. ncbi request reprint Psychological morbidity in caregivers is associated with depression in patients with dementia
    H Brodaty
    Academic Department of Psychogeriatrics, Prince Henry Hospital, School of Psychiatry, University of New South Wales, Sydney, Australia
    Alzheimer Dis Assoc Disord 12:62-70. 1998
    ..This new finding of a link between patient depression and caregiver psychological morbidity has implications for more focused treatment programs for both caregivers and patients...
  43. ncbi request reprint Clinical determinants of dementia and mild cognitive impairment following ischaemic stroke: the Sydney Stroke Study
    P S Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Dement Geriatr Cogn Disord 21:275-83. 2006
    ..Dementia following stroke is common but its determinants are still incompletely understood...
  44. ncbi request reprint Use of psychotropics in Sydney nursing homes: associations with depression, psychosis, and behavioral disturbances
    B Draper
    Schools of Psychiatry and Community Medicine, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 13:107-20. 2001
    ....
  45. doi request reprint The relationship of current depressive symptoms and past depression with cognitive impairment and instrumental activities of daily living in an elderly population: the Sydney Memory and Ageing Study
    S Reppermund
    Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Randwick Campus, Building R1f, UNSW, NSW 2052, Sydney, Australia
    J Psychiatr Res 45:1600-7. 2011
    ..These results support the view that current and past depressive episodes are associated with poorer cognitive performance but not with functional abilities...
  46. doi request reprint Levels and rates of depression among Chinese people living in Chinese ethno-specific and mainstream residential care in Sydney
    Ivanna Goh
    Primary Dementia Collaborative Research Centre and School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 22:237-45. 2010
    ..Australia has a growing aging migrant population and rates of depression in NHs are high, but the prevalence of depression in culturally and linguistically diverse residents has received little attention in the research literature...
  47. ncbi request reprint 1H MRS in stroke patients with and without cognitive impairment
    A J Ross
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Neurobiol Aging 26:873-82. 2005
    ..Moreover, cortical regions not obviously infarcted may have dysfunctional neurons, the pathophysiological basis for which needs further study...
  48. doi request reprint Prevalence and characteristics of depression in mild cognitive impairment: the Sydney Memory and Ageing Study
    Z Shahnawaz
    Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia
    Acta Psychiatr Scand 127:394-402. 2013
    ..Depression might be a risk factor for dementia. However, little is known about the prevalence of depressive symptoms in mild cognitive impairment (MCI) and whether mood or motivation-related symptoms are predominant...
  49. ncbi request reprint A 25-year longitudinal, comparison study of the outcome of depression
    H Brodaty
    School of Psychiatry, University of New South Wales, Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia
    Psychol Med 31:1347-59. 2001
    ..CONCLUSION: Even after 25 years, severe depressive disorders appear to have poor long-term outcomes. Patients with chronic outcomes over 15 years can improve when followed over longer periods...
  50. ncbi request reprint Schizophrenia with onset after age 50 years. 2: Neurological, neuropsychological and MRI investigation
    P Sachdev
    School of Psychiatry, University of New South Wales, Neuropsychiatric Institute, Prince of Wales Hospital, Sydney
    Br J Psychiatry 175:416-21. 1999
    ..Late-onset schizophrenia (LOS) may have a basis in age-related coarse brain disease, but empirical support for this is conflicting...
  51. ncbi request reprint Do extrapyramidal features in Alzheimer patients treated with acetylcholinesterase inhibitors predict disease progression?
    H Brodaty
    School of Psychiatry, University of New South Wales, Kensington, Australia
    Aging Ment Health 11:451-6. 2007
    ..However, EPS did not predict more rapid cognitive or functional decline of patients taking donepezil or response to donepezil. The presence of EPS was a risk factor both for institutionalisation and for death...
  52. ncbi request reprint Neuropsychological performance and dementia in depressed patients after 25-year follow-up: a controlled study
    H Brodaty
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, School of Psychiatry, University of New South Wales, Randwick, Australia
    Psychol Med 33:1263-75. 2003
    ..Some studies have found evidence for a higher incidence of subsequent cognitive impairment or dementia, while others have refuted this...
  53. ncbi request reprint Hippocampal size and dementia in stroke patients: the Sydney stroke study
    P S Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia Neuropsychiatric Institute, The Prince of Wales Hospital, Sydney, Australia
    J Neurol Sci 260:71-7. 2007
    ..Hippocampal atrophy is an early feature of Alzheimer's disease (AD) but it has also been reported in vascular dementia (VaD). It is uncertain whether hippocampal size can help differentiate the two disorders...
  54. ncbi request reprint The prevalence of "cognitive impairment no dementia" in community-dwelling elderly: a pilot study
    L F Low
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, New South Wales, Australia
    Aust N Z J Psychiatry 38:725-31. 2004
    ..To determine the prevalence of "cognitive impairment no dementia" (CIND) and "amnestic mild cognitive impairment" (aMCI) in a population sample of 70-79-year-olds and the risk factors for CIND...
  55. ncbi request reprint Prediction of cognitive decline after stroke using proton magnetic resonance spectroscopy
    Amy J Ross
    Neuropsychiatric Institute, Euroa Centre, Prince of Wales Hospital, Barker Street, Randwick, NSW, Australia
    J Neurol Sci 251:62-9. 2006
    ..In stroke/TIA patients, the (1)H-MRS measures were better predictors of cognitive decline than structural measures. (1)H-MRS may be useful in assessing early cognitive impairment after stroke/TIA and in normal ageing...
  56. doi request reprint Behavioral and psychological symptoms associated with dementia subtype and severity
    Claire Thompson
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia
    Int Psychogeriatr 22:300-5. 2010
    ....
  57. ncbi request reprint Effect of white matter hyperintensities on cortical cerebral blood volume using perfusion MRI
    Wei Wen
    Neuropsychiatric Institute, The Prince of Wales Hospital, Randwick, New South Wales 2031, Australia
    Neuroimage 21:1350-6. 2004
    ..In conclusion, T2-weighted WMHs are associated with reduced rCBV in the cerebral cortex, particularly in individuals with extensive hyperintensities...
  58. ncbi request reprint The relationship between self-destructive behaviour and nursing home environment
    L F Low
    Department of Old Age Psychiatry, Prince of Wales Hospital, Sydney, NSW, Australia
    Aging Ment Health 8:29-33. 2004
    ..The relationship between nursing home environment and self-destructive behaviours and the environment is complex and there needs to be an individualized approach to placement...
  59. ncbi request reprint The Prince Henry Hospital dementia caregivers' training programme
    H Brodaty
    Academic Department of Psychogeriatrics, Prince Henry Hospital, Sydney, Australia
    Int J Geriatr Psychiatry 12:183-92. 1997
    ..To describe the theory, elements and practice of a successful caregiver training programme; and report the 8-year outcome...
  60. ncbi request reprint "Side effects" of ECT are mainly depressive phenomena and are independent of age
    H Brodaty
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Affect Disord 66:237-45. 2001
    ..The aetiology of reported side effects of electroconvulsive therapy (ECT) is unclear. We examined the interaction of depression and age on adverse neuropsychological and putative side effects of ECT...
  61. doi request reprint A pilot study of differences in behavioral and psychological symptoms of dementia in nursing home residents in Sydney and Shanghai
    Helen Zong Ying Wu
    Primary Dementia Collaborative Research Centre, University of New South Wales, Coogee, Australia
    Int Psychogeriatr 21:476-84. 2009
    ....
  62. ncbi request reprint Randomized controlled trial of different models of care for nursing home residents with dementia complicated by depression or psychosis
    Henry Brodaty
    School of Psychiatry, University of New South Wales and the Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia
    J Clin Psychiatry 64:63-72. 2003
    ....
  63. doi request reprint Impairment in instrumental activities of daily living with high cognitive demand is an early marker of mild cognitive impairment: the Sydney Memory and Ageing Study
    S Reppermund
    Centre for Healthy Brain Ageing, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney, Australia
    Psychol Med 43:2437-45. 2013
    ....
  64. ncbi request reprint The neuropsychological profile of vascular cognitive impairment in stroke and TIA patients
    P S Sachdev
    Schools of Psychiatry and Medicine, University of New South Wales, Australia
    Neurology 62:912-9. 2004
    ..To characterize the neuropsychological profile of vascular cognitive impairment (VCI) and vascular dementia (VaD)...
  65. ncbi request reprint Children of a cohort of depressed patients 25 years later: psychopathology and relationships
    C Peisah
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia
    J Affect Disord 82:385-94. 2004
    ..It was hypothesised that children of patients hospitalised for depression 25 years ago would have more psychological morbidity and relationship difficulties than children of a surgical comparison group...
  66. ncbi request reprint Hippocampus and amygdala volumes in elderly schizophrenic patients as assessed by magnetic resonance imaging
    P Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychiatry Clin Neurosci 54:105-12. 2000
    ..This pilot analysis in LOS subjects argues against the condition being secondary to Alzheimer's disease...
  67. ncbi request reprint Longitudinal changes during aging using proton magnetic resonance spectroscopy
    Amy J Ross
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Gerontol A Biol Sci Med Sci 61:291-8. 2006
    ....
  68. ncbi request reprint Cognitive disinhibition and socioemotional functioning in Alzheimer's disease
    Scott Nash
    School of Psychology, University of New South Wales, Sydney 2052, Australia
    J Int Neuropsychol Soc 13:1060-4. 2007
    ..Controlling for general cognitive status, in the AD (but not the control) group, reduced cognitive inhibition was associated with lower levels of depression. The theoretical and practical implications of these results are discussed...
  69. doi request reprint Diffusion tensor imaging of the posterior cingulate is a useful biomarker of mild cognitive impairment
    Terence C Chua
    School of Psychiatry, University of New South Wales, NSW, Australia
    Am J Geriatr Psychiatry 17:602-13. 2009
    ..Biomarkers may help identify individuals at greatest risk of progressive decline. The authors examine a novel neuroimaging technique, diffusion tensor imaging (DTI) as a potential biomarker of MCI...
  70. doi request reprint The Falls Efficacy Scale International (FES-I). A comprehensive longitudinal validation study
    Kim Delbaere
    Falls and Balance Research Group, Prince of Wales Medical Research Institute, University of New South Wales, Randwick, Sydney, Australia
    Age Ageing 39:210-6. 2010
    ....
  71. doi request reprint Relationships between serum vitamin D levels, neuromuscular and neuropsychological function and falls in older men and women
    J C Menant
    Falls and Balance Research Group, Neuroscience Research Australia, University of New South Wales, Barker Street, Randwick, NSW 2031, Sydney, Australia
    Osteoporos Int 23:981-9. 2012
    ..In men, vitamin D insufficiency was associated with an increased risk of falling...
  72. ncbi request reprint Reliability and validity of ratings of signal hyperintensities on MRI by visual inspection and computerised measurement
    P Sachdev
    School of Psychiatry, University of New South Wales, Kensington, Sydney, Australia
    Psychiatry Res 92:103-15. 1999
    ..Visual ratings should therefore be considered adequate for most clinical and research purposes, but such ratings should be accompanied by adequate training and the provision of standard reference images...
  73. ncbi request reprint Progression of cognitive impairment in stroke patients
    P S Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Neurology 63:1618-23. 2004
    ..To examine the progression of neuropsychological deficits in stroke patients with and without cognitive impairment...
  74. ncbi request reprint Suicidal ideation and the 'wish to die' in dementia patients: the role of depression
    B Draper
    Academic Department of Psychogeriatrics, Prince Henry Hospital, University of New South Wales, Sydney, Australia
    Age Ageing 27:503-7. 1998
    ..To determine the prevalence of self-reported suicidal ideation and the 'wish to die' in dementia patients, their association with depressive symptoms and the type of dementia...
  75. ncbi request reprint Quantitative study of signal hyperintensities on T2-weighted magnetic resonance imaging in late-onset schizophrenia
    P Sachdev
    School of Psychiatry, University of New South Wales and the Neuropsychiatric Institute, Prince Henry and Prince of Wales Hospitals, Sydney, Australia
    Am J Psychiatry 156:1958-67. 1999
    ..The authors investigated the extent and distribution of signal hyperintensities on T2-weighted magnetic resonance imaging (MRI) of the brains of subjects with late-onset schizophrenia...
  76. ncbi request reprint The Sydney Holocaust study: posttraumatic stress disorder and other psychosocial morbidity in an aged community sample
    Charmaine Joffe
    School of Psychiatry, University of New South Wales, Sydney, Australia
    J Trauma Stress 16:39-47. 2003
    ..The more severe the trauma the greater the level of psychological morbidity. Despite normal social and daily functioning, psychological morbidity following massive trauma endures...
  77. doi request reprint The effects of age and sex on cortical sulci in the elderly
    Tao Liu
    School of Design, Communication and I T, The University of Newcastle, and Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, NSW, Australia
    Neuroimage 51:19-27. 2010
    ..This study establishes a reference for future studies of age-related brain changes and neurodegenerative diseases in the elderly...
  78. ncbi request reprint The differentiation of mild frontotemporal dementia from Alzheimer's disease and healthy aging by neuropsychological tests
    Alexandra J Walker
    Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia
    Int Psychogeriatr 17:57-68. 2005
    ..This study aimed to investigate neuropsychological function in FTD of mild severity and compare it to that of mild AD and healthy control participants...
  79. pmc Antihypertensives for combating dementia? A perspective on candidate molecular mechanisms and population-based prevention
    M Valenzuela
    Regenerative Neuroscience Group, Brain and Mind Research Institute, University of Sydney, Sydney, NSW, Australia
    Transl Psychiatry 2:e107. 2012
    ....
  80. ncbi request reprint An electroencephalographic investigation of late-onset schizophrenia
    P Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 11:421-9. 1999
    ..Our study does not suggest the presence of underlying dementia in schizophrenia of late onset...
  81. ncbi request reprint Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older
    Jean Hollis
    School of Psychology, University of Sydney, Sydney, Australia
    Am J Geriatr Psychiatry 15:932-41. 2007
    ..To establish the instantaneous relative risk (RR) of death associated with individual antipsychotic drugs, carbamazepine and sodium valproate for those 65 years and older...
  82. ncbi request reprint The neglect of somatoform disorders by old age psychiatry: some explanations and suggestions for future research
    Chanaka Wijeratne
    St George Hospital, NSW, Australia
    Int J Geriatr Psychiatry 18:812-9. 2003
    ..The somatoform disorders have long been ignored by old age psychiatry. The main aim of this paper is to identify and examine possible reasons for this neglect...
  83. ncbi request reprint Aggression in the elderly
    Henry Brodaty
    School of Psychiatry, University of New South Wales, Prince of Wales Hospital Sydney, Australia
    J Clin Psychiatry 64:36-43. 2003
    ..Management of aggression should include comprehensive assessment of medical, psychological, and environmental variables...
  84. ncbi request reprint Diagnosing dementia in primary care: the accuracy of informant reports
    Nicola M Kemp
    Academic Department for Old Age Psychiatry, Prince of Wales Hospital, Sydney, Australia
    Alzheimer Dis Assoc Disord 16:171-6. 2002
    ....
  85. ncbi request reprint Risk of death associated with antipsychotic drug dispensing in residential aged care facilities
    Jean Hollis
    School of Psychology, University of Sydney, Sydney, New South Wales, Australia
    Aust N Z J Psychiatry 41:751-8. 2007
    ..To establish the instantaneous relative risk (RR) associated with the dispensing of individual antipsychotic drugs, carbamazepine and valproate for those > or = 65 years who resided in an aged care facility...
  86. ncbi request reprint The establishment of a mood disorders unit
    H Brodaty
    Mood Disorders Unit, Prince Henry Hospital, Little Bay, NSW
    Aust N Z J Psychiatry 21:375-81. 1987
    ..It is argued that a specialised diagnosis-related facility is feasible within a general hospital psychiatry service with area health commitments...
  87. doi request reprint Functional alterations in brain activation and deactivation in mild cognitive impairment in response to a graded working memory challenge
    N A Kochan
    Brain and Ageing Research Program, School of Psychiatry, University of New South Wales, Sydney, NSW 2052, Australia
    Dement Geriatr Cogn Disord 30:553-68. 2010
    ..To investigate dynamic changes in functional brain activity in mild cognitive impairment (MCI) in response to a graded working memory (WM) challenge with increasing memory load...
  88. ncbi request reprint Relationship between plasma homocysteine levels and brain atrophy in healthy elderly individuals
    P S Sachdev
    School of Psychiatry, University of New South Wales, Australia
    Neurology 58:1539-41. 2002
    ..34) after controlling for age, folate, B12, creatinine, and white matter disease (OR = 2.3; CI, 1.03-5.09)...
  89. ncbi request reprint Types of nursing home residents with self-destructive behaviours: analysis of the Harmful Behaviours Scale
    Brian Draper
    Schools of Psychiatry and Public Health and Community Medicine, University of New South Wales, Australia
    Int J Geriatr Psychiatry 17:670-5. 2002
    ..To investigate the types of self-destructive behaviours identified by the Harmful Behaviours Scale (HBS) and the variables associated with them...
  90. ncbi request reprint Cognitive correlates of 1H MRS measures in the healthy elderly brain
    Amy J Ross
    School of Psychiatry, University of New South Wales, Sydney, NSW, Australia
    Brain Res Bull 66:9-16. 2005
    ..This research highlights the importance of the relationship between regional brain changes and cognitive function in the ageing brain, and suggests that MRS may be a sensitive marker of subclinical change in cognition...
  91. doi request reprint Will testing for apolipoprotein E assist in tailoring dementia risk reduction? A review
    Lee Fay Low
    Dementia Collaborative Research Centre Assessment and Better Care Outcomes, University of New South Wales, Kensington 2500, New South Wales, Australia
    Neurosci Biobehav Rev 34:408-37. 2010
    ..There was inconsistent or contradictory evidence for other environmental factors reviewed. There is insufficient evidence for the recommendation of ApoE testing to assist with tailoring risk reduction recommendations for dementia...
  92. doi request reprint Future research on dementia relating to culturally and linguistically diverse communities
    Lee Fay Low
    Dementia Collaborative Research Centre, University of New South Wales, Sydney, Australia
    Australas J Ageing 28:144-8. 2009
    ..The paper closes with some strategies to encourage CALD research. The material presented here will provide guidance for future research endeavours...
  93. doi request reprint Who does well after a stroke? The Sydney stroke study
    Adrienne Withall
    School of Psychiatry, University of New South Wales, Randwick, NSW, Australia
    Aging Ment Health 13:693-8. 2009
    ..We conclude that people can have good outcomes in the year after stroke except if they experience further cerebrovascular events and/or have risk factors for cerebrovascular disease. Brain reserve appears to be protective...
  94. doi request reprint The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years
    Perminder S Sachdev
    Brain and Ageing Research Program, School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Int Psychogeriatr 22:1248-64. 2010
    ....
  95. doi request reprint Prospective memory function in mild cognitive impairment and early dementia
    Claire Thompson
    School of Psychology, University of New South Wales, Sydney, NSW 2052, Australia
    J Int Neuropsychol Soc 16:318-25. 2010
    ..It is suggested that, while other cognitive deficits contribute to these difficulties, there is something unique to prospective remembering that may be additionally disrupted in these groups...
  96. doi request reprint The determinants and longitudinal course of post-stroke mild cognitive impairment
    Perminder S Sachdev
    School of Psychiatry and Brain and Ageing Program, University of New South Wales, Randwick, New South Wales
    J Int Neuropsychol Soc 15:915-23. 2009
    ..The major determinant of decline and categorical transition was impaired performance at baseline, suggesting that those with mild impairment post-stroke are more vulnerable to subsequent decline...
  97. ncbi request reprint Regional cerebral blood flow deficits in mild Alzheimer's disease using high resolution single photon emission computerized tomography
    Julian N Trollor
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Psychiatry Clin Neurosci 59:280-90. 2005
    ..Discriminant function analysis indicated that rCBF in the prefrontal polar regions achieved the best classification of cases. SPECT has utility in the diagnostic assessment of AD if standardized and semiquantitative techniques are used...
  98. ncbi request reprint A high-resolution single photon emission computed tomography study of verbal recognition memory in Alzheimer's disease
    Julian N Trollor
    School of Psychiatry, University of New South Wales, Randwick, Australia
    Dement Geriatr Cogn Disord 21:267-74. 2006
    ..In view of the recent technological advances and its ease of availability, we used single photon emission computed tomography (SPECT) to examine the performance of early Alzheimer's disease (AD) subjects on a verbal recognition memory task...
  99. doi request reprint A longitudinal study examining the independence of apathy and depression after stroke: the Sydney Stroke Study
    Adrienne Withall
    School of Psychiatry, University of New South Wales, Randwick, Australia
    Int Psychogeriatr 23:264-73. 2011
    ..This is the first study to investigate the relationship of apathy and depression longitudinally following stroke and to examine the association with dementia...
  100. ncbi request reprint Progression of white matter hyperintensities in elderly individuals over 3 years
    Perminder Sachdev
    School of Psychiatry, University of New South Wales, Sydney, Australia
    Neurology 68:214-22. 2007
    ..The aims of this study were to examine white matter hyperintensities (WMHs) in the brains of elderly individuals, the rate of progression, the anatomic regions most vulnerable, and the predictors of change...
  101. ncbi request reprint A tiered model of psychogeriatric service delivery: an evidence-based approach
    Brian Draper
    School of Psychiatry, University of NSW, Sydney, Australia
    Int J Geriatr Psychiatry 21:645-53. 2006
    ..Previous models of mental health care for older persons have not considered the full spectrum of mental disorders...