U A Bommer

Summary

Affiliation: University of Wollongong
Country: Australia

Publications

  1. doi request reprint Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway
    Ulrich Axel Bommer
    Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong 2522 NSW, Australia Graduate School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong 2522 NSW, Australia Electronic address
    Cell Signal 27:1557-68. 2015
  2. doi request reprint Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses
    U A Bommer
    Division of Basic Medical Sciences, St George s, University of London, London, UK
    Oncogene 29:763-73. 2010
  3. ncbi request reprint The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle
    Y Gachet
    Divisions of Biochemistry and Immunology, St George s Hospital Medical School, London, UK
    J Cell Sci 112:1257-71. 1999
  4. ncbi request reprint Translational control: the cancer connection
    M J Clemens
    Department of Biochemistry, St George s Hospital Medical School, London, UK
    Int J Biochem Cell Biol 31:1-23. 1999

Collaborators

Detail Information

Publications4

  1. doi request reprint Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway
    Ulrich Axel Bommer
    Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong 2522 NSW, Australia Graduate School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong 2522 NSW, Australia Electronic address
    Cell Signal 27:1557-68. 2015
    ..This explains why TCTP levels are frequently increased in cancers, since mTORC1 signalling is hyperactive in ~80% of tumours. ..
  2. doi request reprint Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses
    U A Bommer
    Division of Basic Medical Sciences, St George s, University of London, London, UK
    Oncogene 29:763-73. 2010
    ..Our results imply that cellular TCTP levels influence sensitivity to apoptosis and that PKR may exert its proapoptotic effects at least in part through downregulation of TCTP via eIF2alpha phosphorylation...
  3. ncbi request reprint The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle
    Y Gachet
    Divisions of Biochemistry and Immunology, St George s Hospital Medical School, London, UK
    J Cell Sci 112:1257-71. 1999
    ..4) Overexpression of P23 results in cell growth retardation and in alterations of cell morphology. Moreover, elevation of P23 levels leads to microtubule rearrangements and to an increase in microtubule mass and stability...
  4. ncbi request reprint Translational control: the cancer connection
    M J Clemens
    Department of Biochemistry, St George s Hospital Medical School, London, UK
    Int J Biochem Cell Biol 31:1-23. 1999
    ..The purpose of this article is to give an overview of the field and to indicate where we may expect developments to occur in the next few years...