Marie A Bogoyevitch

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Identification of the critical features of a small peptide inhibitor of JNK activity
    Renae K Barr
    Department of Biochemistry, University of Western Australia, Crawley 6009, Australia
    J Biol Chem 277:10987-97. 2002
  2. ncbi request reprint Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system
    M A Bogoyevitch
    Department of Biochemistry, University of Western Australia, Nedlands, Australia
    Cardiovasc Res 45:826-42. 2000
  3. ncbi request reprint Therapeutic promise of JNK ATP-noncompetitive inhibitors
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Trends Mol Med 11:232-9. 2005
  4. ncbi request reprint The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia, Australia
    Bioessays 28:923-34. 2006
  5. ncbi request reprint Counting on mitogen-activated protein kinases--ERKs 3, 4, 5, 6, 7 and 8
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Cell Signal 16:1345-54. 2004
  6. ncbi request reprint An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Australia
    Cardiovasc Res 63:208-16. 2004
  7. pmc Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Microbiol Mol Biol Rev 70:1061-95. 2006
  8. ncbi request reprint Peptide inhibitors of protein kinases-discovery, characterisation and use
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Biochim Biophys Acta 1754:79-99. 2005
  9. ncbi request reprint Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Biochim Biophys Acta 1697:89-101. 2004
  10. ncbi request reprint Taking the cell by stealth or storm? Protein transduction domains (PTDs) as versatile vectors for delivery
    Marie A Bogoyevitch
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley 6009, Australia
    DNA Cell Biol 21:879-94. 2002

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Identification of the critical features of a small peptide inhibitor of JNK activity
    Renae K Barr
    Department of Biochemistry, University of Western Australia, Crawley 6009, Australia
    J Biol Chem 277:10987-97. 2002
    ..These studies thus define a small peptide inhibitor sequence of JNKs based on the JIP proteins...
  2. ncbi request reprint Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system
    M A Bogoyevitch
    Department of Biochemistry, University of Western Australia, Nedlands, Australia
    Cardiovasc Res 45:826-42. 2000
    ..This review focuses on the recent progress made in the understanding of the regulation and function of MAPKs in the cardiovascular system, with particular emphasis being placed on the events in the cardiac ventricular myocyte...
  3. ncbi request reprint Therapeutic promise of JNK ATP-noncompetitive inhibitors
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Trends Mol Med 11:232-9. 2005
    ....
  4. ncbi request reprint The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia, Australia
    Bioessays 28:923-34. 2006
    ..These results emphasise the differences in the roles played by JNK isoforms in vivo and suggest that the design of JNK inhibitors for subsequent therapeutic uses may benefit from selective inhibition of individual JNK isoforms...
  5. ncbi request reprint Counting on mitogen-activated protein kinases--ERKs 3, 4, 5, 6, 7 and 8
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Cell Signal 16:1345-54. 2004
    ..It is clear from these studies that these additional ERKs show similarities to ERK1 and ERK2, but with some interesting differences that challenge the paradigm of the archetypical ERK1/2 MAPK pathway...
  6. ncbi request reprint An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Australia
    Cardiovasc Res 63:208-16. 2004
    ..These beneficial effects of Epo should stimulate further research into the actions of Epo...
  7. pmc Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Microbiol Mol Biol Rev 70:1061-95. 2006
    ..Further characterization of the substrates of JNK should provide clearer explanations of the intracellular actions of the JNKs and may allow new avenues for targeting the JNK pathways with therapeutic agents downstream of JNK itself...
  8. ncbi request reprint Peptide inhibitors of protein kinases-discovery, characterisation and use
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Biochim Biophys Acta 1754:79-99. 2005
    ..These approaches are therefore providing exciting new opportunities in the development of ATP non-competitive inhibitors of protein kinases...
  9. ncbi request reprint Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Biochim Biophys Acta 1697:89-101. 2004
    ..Alternative peptide-based inhibitors of JNKs are now also in development. The possible identification of allosteric modifiers rather than direct ATP competitors could lead to inhibitors of unprecedented specificity and efficacy...
  10. ncbi request reprint Taking the cell by stealth or storm? Protein transduction domains (PTDs) as versatile vectors for delivery
    Marie A Bogoyevitch
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley 6009, Australia
    DNA Cell Biol 21:879-94. 2002
    ..Recent examples of the range of potential applications are also discussed...
  11. ncbi request reprint Intact mitochondrial electron transport function is essential for signalling by hydrogen peroxide in cardiac myocytes
    M A Bogoyevitch
    Department of Biochemistry, University of Western Australia, Nedlands, Western Australia, 6907, Australia
    J Mol Cell Cardiol 32:1469-80. 2000
    ..These studies suggest a novel mechanism of regulation of the ERK MAPK pathway and oxidative stress signalling by hydrogen peroxide...
  12. ncbi request reprint Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1
    Renae K Barr
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, Western Australia
    J Biol Chem 279:43178-89. 2004
    ..Therefore, the results of our unbiased reverse two-hybrid screening approach have identified residues of JNK responsible for binding JIP-1-based peptides as well as MKK4 or MKK7...
  13. ncbi request reprint Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    Biochem Biophys Res Commun 319:130-7. 2004
    ..Our results suggest that SAPK3 and JNK may share a common target at the mitochondria and provide new insights into the substrate recognition by SAPK3...
  14. ncbi request reprint The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK
    Renae K Barr
    Department of Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, WA 6009, Australia
    J Biol Chem 279:36327-38. 2004
    ..TI-JIP is therefore a unique KIM-based inhibitor of JNK activity...
  15. ncbi request reprint Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, University of Western Australia, Western Australia 6009, Australia
    Biochim Biophys Acta 1744:68-75. 2005
    ..This is a new mechanism for the regulation of SAPK3 and suggests that its intracellular activity should not be solely assessed by its phosphorylation status...
  16. ncbi request reprint Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase
    Peter G Arthur
    School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia, Australia
    J Neurochem 102:65-76. 2007
    ..The potent neuroprotective properties of JNK peptide inhibitors likely reflects their abilities to prevent cell death by necrosis as well as apoptosis...
  17. ncbi request reprint Necrotic death without mitochondrial dysfunction-delayed death of cardiac myocytes following oxidative stress
    Tammy M Casey
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Biochim Biophys Acta 1773:342-51. 2007
    ..Our results suggest that this delayed form necrosis may also comprise an ordered series of events involving pathways amenable to therapeutic modulation...
  18. ncbi request reprint Contrasting actions of prolonged mitogen-activated protein kinase activation on cell survival
    Bahareh Badrian
    Biochemistry and Molecular Biology, University of Western Australia UWA, and Lions Eye Institute, Crawley, WA 6009, Australia
    Biochem Biophys Res Commun 345:843-50. 2006
    ..Pre-incubation with U0126 inhibited menadione-induced death. Our results are the first to show that MEK-ERK signalling can act to increase or decrease cell survival, the outcome depending on the form of stress stimulus encountered...
  19. pmc c-Jun N-terminal kinase phosphorylation of stathmin confers protection against cellular stress
    Dominic C H Ng
    Department of Biochemistry, Bio21 Institute, University of Melbourne, Parkville, 3010 Victoria, Australia
    J Biol Chem 285:29001-13. 2010
    ..Our findings show that JNK targeting of STMN represents a novel stress-activated cytoprotective mechanism involving microtubule network changes...
  20. ncbi request reprint Gene expression profiling reveals complex changes following MEK-EE expression in cardiac myocytes
    Bahareh Badrian
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Int J Biochem Cell Biol 39:349-65. 2007
    ..Our results reveal the complexity of transcriptional changes that follow the activation of the ERK signalling pathway in these cells and suggest that activation of this MAPK pathway impinges on diverse cellular functions...
  21. ncbi request reprint Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts
    Dominic C H Ng
    Cell Signalling Laboratory, Biochemistry and Molecular Biology in the School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Cardiovasc Res 57:333-46. 2003
    ....
  22. ncbi request reprint A role for the extracellular signal-regulated kinase and p38 mitogen-activated protein kinases in interleukin-1 beta-stimulated delayed signal tranducer and activator of transcription 3 activation, atrial natriuretic factor expression, and cardiac myocyte
    D C Ng
    Department of Biochemistry, University of Western Australia, Crawley 6009, Australia
    J Biol Chem 276:29490-8. 2001
    ..Thus, the role of MAPKs in the hypertrophic response can be dictated at least partly by the nature of the hypertrophic agent employed...
  23. ncbi request reprint A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Australia
    Drug Discov Today 12:622-33. 2007
    ..These inhibitors promise exciting therapeutic opportunities by exploiting new mechanisms of action and may thus allow greater specificity in protein kinase inhibition with fewer off-target side effects...
  24. ncbi request reprint Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor
    Tulene S Kendrick
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Biol Chem 279:326-40. 2004
    ..Our results suggest that direct binding of Shc by the GCSF-R is not essential for JNK activation...
  25. doi request reprint Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia
    Cecilia M Prele
    School of Anatomy and Human Biology, University of Western Australia, Crawley, Perth 6009, Australia
    Cardiovasc Pathol 21:17-27. 2012
    ..The aim of the present study was to assess the structural and ex vivo functional impacts of long-term cardiomyocyte-specific insulin-like growth factor-1 overexpression in hearts of transgenic αMHC-IGF-1 Ea mice...
  26. doi request reprint Changes in oxygen tension affect cardiac mitochondrial respiration rate via changes in the rate of mitochondrial hydrogen peroxide production
    Carla A Di Maria
    School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Australia
    J Mol Cell Cardiol 47:49-56. 2009
    ..These findings indicate that oxygen-dependent decreases in the rate of mitochondrial hydrogen peroxide production can decrease cardiac mitochondrial respiration...
  27. ncbi request reprint Histone H4 histidine kinase displays the expression pattern of a liver oncodevelopmental marker
    Eiling Tan
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Carcinogenesis 25:2083-8. 2004
    ....
  28. ncbi request reprint Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3)
    Naomi W Court
    Department of Biochemistry, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Mol Cell Cardiol 34:413-26. 2002
    ..These differences between p38- alpha/ beta and SAPK3 probably reflect the specialized functions of SAPK3 and emphasize the need to evaluate SAPK3 upstream activators and downstream targets in the heart...
  29. doi request reprint Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle
    Miranda D Grounds
    School of Anatomy and Human Biology, The University of Western Australia, Crawley, Western Australia, Australia
    Clin Exp Pharmacol Physiol 35:846-51. 2008
    ....
  30. ncbi request reprint Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition
    Dominic C H Ng
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Western Australia, Australia
    Cell Motil Cytoskeleton 65:40-58. 2008
    ..Sarcomere formation in cardiac myocytes therefore, does not appear to require an intact MT network and thus we conclude that a functional MT array appears to be dispensable for myofibrillogenesis...
  31. ncbi request reprint Changes in the transcriptional profile of cardiac myocytes following green fluorescent protein expression
    Bahareh Badrian
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular, and Chemical Sciences, University of Western Australia, Perth, Western Australia, Australia
    DNA Cell Biol 26:727-36. 2007
    ..Our analysis thus indicates the broader consequences of GFP expression in altering gene expression profiles in cardiac cells. Care should therefore be taken when using GFP expression as a control in gene expression studies...
  32. pmc Mitochondrial ATP production is necessary for activation of the extracellular-signal-regulated kinases during ischaemia/reperfusion in rat myocyte-derived H9c2 cells
    L Abas
    Department of Biochemistry, University of Western Australia, Nedlands, W A 6907, Australia
    Biochem J 349:119-26. 2000
    ..Our results reveal the importance of cellular metabolism in ERK activation, and introduce ATP as a novel participant in the mechanisms underlying the ERK cascade...
  33. ncbi request reprint The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs)
    R K Barr
    Cell Signalling Laboratory, Department of Biochemistry, University of Western Australia, 35 Stirling Highway, WA 6009, Crawley, Australia
    Int J Biochem Cell Biol 33:1047-63. 2001
    ..Recent work has also highlighted their importance in programmed cell death. Thus, the JNK MAPKs may provide a critical target for regulation in both normal and diseased states...
  34. ncbi request reprint Proteomic analysis reveals different protein changes during endothelin-1- or leukemic inhibitory factor-induced hypertrophy of cardiomyocytes in vitro
    Tammy M Casey
    Department of Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Mol Cell Proteomics 4:651-61. 2005
    ..This is consistent with the differences in morphologies noted as well as the different signaling pathways utilized by these different stimuli...
  35. ncbi request reprint Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology
    Haslett R Grounds
    Biochemistry and Molecular Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Cell Biochem 95:529-42. 2005
    ..These results reveal a role for RhoA in the maintenance of normal myocyte morphology...
  36. ncbi request reprint The role of stem cells in skeletal and cardiac muscle repair
    Miranda D Grounds
    Department of Anatomy and Human Biology, The University of Western Australia, Crawley, Western Australia
    J Histochem Cytochem 50:589-610. 2002
    ..For heart muscle, experiments showing the participation of bone marrow-derived stem cells and endothelial cells in the repair of damaged cardiac muscle are encouraging...
  37. ncbi request reprint Activation of mitogen-activated protein kinase pathways by the granulocyte colony-stimulating factor receptor: mechanisms and functional consequences
    Tulene S Kendrick
    Western Australian Institute for Medical Research, Perth, Australia
    Front Biosci 12:591-607. 2007
    ..In addition, the activation of individual MAPK pathways appears to contribute to distinct biological outcomes. Thus, MAPK activation may be an important mediator of the actions of G-CSF...
  38. ncbi request reprint Inhibitors of c-Jun N-terminal kinases: JuNK no more?
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia
    Biochim Biophys Acta 1784:76-93. 2008
    ..We conclude by raising a number of questions that should be considered in the quest for JNK-specific inhibitors...
  39. pmc Reciprocal regulation of glutathione S-transferase spliceforms and the Drosophila c-Jun N-terminal kinase pathway components
    Rungrutai Udomsinprasert
    Institute of Molecular Biology and Genetics, Mahidol University, Salaya Campus, Nakorn Pathom 73170, Thailand
    Biochem J 383:483-90. 2004
    ..These results emphasize that different GST spliceforms possess different properties, both in their catalytic function and in their regulation of signalling through the JNK pathway...
  40. doi request reprint Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy
    Tatiana Tsoutsman
    Agnes Ginges Centre for Molecular Cardiology, Centenary Institute, Locked Bag 6, Newtown, NSW 2042, Australia
    Circulation 117:1820-31. 2008
    ..These observations suggest a relationship between the number of gene mutations and phenotype severity in FHC...