Marie A Bogoyevitch

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia
    Biochim Biophys Acta 1804:463-75. 2010
  2. ncbi request reprint Inhibitors of c-Jun N-terminal kinases: JuNK no more?
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia
    Biochim Biophys Acta 1784:76-93. 2008
  3. ncbi request reprint Changes in the transcriptional profile of cardiac myocytes following green fluorescent protein expression
    Bahareh Badrian
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular, and Chemical Sciences, University of Western Australia, Perth, Western Australia, Australia
    DNA Cell Biol 26:727-36. 2007
  4. ncbi request reprint A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Australia
    Drug Discov Today 12:622-33. 2007
  5. pmc C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
    Jodi Meyerowitz
    Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
    Mol Neurodegener 6:57. 2011
  6. ncbi request reprint Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1
    Renae K Barr
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, Western Australia
    J Biol Chem 279:43178-89. 2004
  7. ncbi request reprint Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    Biochem Biophys Res Commun 319:130-7. 2004
  8. ncbi request reprint The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK
    Renae K Barr
    Department of Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, WA 6009, Australia
    J Biol Chem 279:36327-38. 2004
  9. doi request reprint Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide
    Kevin R W Ngoei
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    Biochem J 434:399-413. 2011
  10. ncbi request reprint Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, University of Western Australia, Western Australia 6009, Australia
    Biochim Biophys Acta 1744:68-75. 2005

Collaborators

Detail Information

Publications44

  1. doi request reprint c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia
    Biochim Biophys Acta 1804:463-75. 2010
    ..These latest advances highlight the many challenges now faced, particularly in the directed targeting of the JNK isoforms in specific tissues...
  2. ncbi request reprint Inhibitors of c-Jun N-terminal kinases: JuNK no more?
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia
    Biochim Biophys Acta 1784:76-93. 2008
    ..We conclude by raising a number of questions that should be considered in the quest for JNK-specific inhibitors...
  3. ncbi request reprint Changes in the transcriptional profile of cardiac myocytes following green fluorescent protein expression
    Bahareh Badrian
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular, and Chemical Sciences, University of Western Australia, Perth, Western Australia, Australia
    DNA Cell Biol 26:727-36. 2007
    ..Our analysis thus indicates the broader consequences of GFP expression in altering gene expression profiles in cardiac cells. Care should therefore be taken when using GFP expression as a control in gene expression studies...
  4. ncbi request reprint A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Australia
    Drug Discov Today 12:622-33. 2007
    ..These inhibitors promise exciting therapeutic opportunities by exploiting new mechanisms of action and may thus allow greater specificity in protein kinase inhibition with fewer off-target side effects...
  5. pmc C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress
    Jodi Meyerowitz
    Department of Pathology, The University of Melbourne, Victoria, 3010, Australia
    Mol Neurodegener 6:57. 2011
    ..abstract:..
  6. ncbi request reprint Reverse two-hybrid screening identifies residues of JNK required for interaction with the kinase interaction motif of JNK-interacting protein-1
    Renae K Barr
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, Western Australia
    J Biol Chem 279:43178-89. 2004
    ..Therefore, the results of our unbiased reverse two-hybrid screening approach have identified residues of JNK responsible for binding JIP-1-based peptides as well as MKK4 or MKK7...
  7. ncbi request reprint Phosphorylation of the mitochondrial protein Sab by stress-activated protein kinase 3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    Biochem Biophys Res Commun 319:130-7. 2004
    ..Our results suggest that SAPK3 and JNK may share a common target at the mitochondria and provide new insights into the substrate recognition by SAPK3...
  8. ncbi request reprint The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK
    Renae K Barr
    Department of Biochemistry and Molecular Biology, University of Western Australia, Crawley, Perth, WA 6009, Australia
    J Biol Chem 279:36327-38. 2004
    ..TI-JIP is therefore a unique KIM-based inhibitor of JNK activity...
  9. doi request reprint Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide
    Kevin R W Ngoei
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    Biochem J 434:399-413. 2011
    ....
  10. ncbi request reprint Outer membrane protein 25-a mitochondrial anchor and inhibitor of stress-activated protein kinase-3
    Naomi W Court
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, University of Western Australia, Western Australia 6009, Australia
    Biochim Biophys Acta 1744:68-75. 2005
    ..This is a new mechanism for the regulation of SAPK3 and suggests that its intracellular activity should not be solely assessed by its phosphorylation status...
  11. ncbi request reprint Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c-jun N-terminal kinase
    Peter G Arthur
    School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia, Australia
    J Neurochem 102:65-76. 2007
    ..The potent neuroprotective properties of JNK peptide inhibitors likely reflects their abilities to prevent cell death by necrosis as well as apoptosis...
  12. ncbi request reprint Activation of mitogen-activated protein kinase pathways by the granulocyte colony-stimulating factor receptor: mechanisms and functional consequences
    Tulene S Kendrick
    Western Australian Institute for Medical Research, Perth, Australia
    Front Biosci 12:591-607. 2007
    ..In addition, the activation of individual MAPK pathways appears to contribute to distinct biological outcomes. Thus, MAPK activation may be an important mediator of the actions of G-CSF...
  13. pmc WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression
    Marie A Bogoyevitch
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia
    J Cell Sci 125:5096-109. 2012
    ..Our study provides the first functional characterization of WDR62 and has revealed requirements for JNK/WDR62 signaling in mitotic spindle regulation that may be involved in coordinating neurogenesis...
  14. ncbi request reprint Contrasting actions of prolonged mitogen-activated protein kinase activation on cell survival
    Bahareh Badrian
    Biochemistry and Molecular Biology, University of Western Australia UWA, and Lions Eye Institute, Crawley, WA 6009, Australia
    Biochem Biophys Res Commun 345:843-50. 2006
    ..Pre-incubation with U0126 inhibited menadione-induced death. Our results are the first to show that MEK-ERK signalling can act to increase or decrease cell survival, the outcome depending on the form of stress stimulus encountered...
  15. pmc Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes
    Ivan H W Ng
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Victoria 3010, Australia
    Biochem J 447:125-36. 2012
    ..These results highlight STAT3β as a significant transcriptional regulator in its own right, with additional actions to cross-regulate STAT3α phosphorylation and nuclear retention after cytokine stimulation...
  16. ncbi request reprint Gene expression profiling reveals complex changes following MEK-EE expression in cardiac myocytes
    Bahareh Badrian
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Int J Biochem Cell Biol 39:349-65. 2007
    ..Our results reveal the complexity of transcriptional changes that follow the activation of the ERK signalling pathway in these cells and suggest that activation of this MAPK pathway impinges on diverse cellular functions...
  17. pmc c-Jun N-terminal kinase phosphorylation of stathmin confers protection against cellular stress
    Dominic C H Ng
    Department of Biochemistry, Bio21 Institute, University of Melbourne, Parkville, 3010 Victoria, Australia
    J Biol Chem 285:29001-13. 2010
    ..Our findings show that JNK targeting of STMN represents a novel stress-activated cytoprotective mechanism involving microtubule network changes...
  18. doi request reprint Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds
    Kevin R W Ngoei
    Department of Biochemistry and Molecular Biology, University of Melbourne, Victoria, Australia
    Biochim Biophys Acta 1834:1077-88. 2013
    ....
  19. pmc Opposing actions of extracellular signal-regulated kinase (ERK) and signal transducer and activator of transcription 3 (STAT3) in regulating microtubule stabilization during cardiac hypertrophy
    Dominic C H Ng
    Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Victoria 3010, Australia
    J Biol Chem 286:1576-87. 2011
    ..Taken together, our results highlight the opposing actions of STAT3 and ERK pathways in the regulation of MT changes associated with cardiac myocyte hypertrophy...
  20. ncbi request reprint Necrotic death without mitochondrial dysfunction-delayed death of cardiac myocytes following oxidative stress
    Tammy M Casey
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Biochim Biophys Acta 1773:342-51. 2007
    ..Our results suggest that this delayed form necrosis may also comprise an ordered series of events involving pathways amenable to therapeutic modulation...
  21. ncbi request reprint Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Biochim Biophys Acta 1697:89-101. 2004
    ..Alternative peptide-based inhibitors of JNKs are now also in development. The possible identification of allosteric modifiers rather than direct ATP competitors could lead to inhibitors of unprecedented specificity and efficacy...
  22. ncbi request reprint Activation of signal transducer and activator of transcription (STAT) pathways in failing human hearts
    Dominic C H Ng
    Cell Signalling Laboratory, Biochemistry and Molecular Biology in the School of Biomedical and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Cardiovasc Res 57:333-46. 2003
    ....
  23. ncbi request reprint Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor
    Tulene S Kendrick
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Biol Chem 279:326-40. 2004
    ..Our results suggest that direct binding of Shc by the GCSF-R is not essential for JNK activation...
  24. ncbi request reprint Peptide inhibitors of protein kinases-discovery, characterisation and use
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Biochim Biophys Acta 1754:79-99. 2005
    ..These approaches are therefore providing exciting new opportunities in the development of ATP non-competitive inhibitors of protein kinases...
  25. doi request reprint c-Jun N-terminal kinase/c-Jun inhibits fibroblast proliferation by negatively regulating the levels of stathmin/oncoprotein 18
    Yvonne Y C Yeap
    Department of Biochemistry and Molecular Biology, Bio21 Institute, University of Melbourne, Vic, Australia
    Biochem J 430:345-54. 2010
    ....
  26. doi request reprint Tracking protein aggregation and mislocalization in cells with flow cytometry
    Yasmin M Ramdzan
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria, Australia
    Nat Methods 9:467-70. 2012
    ..Combining PulSA with tetracysteine-based oligomer sensors in a cell model of Huntington's disease enabled further separation of cells enriched with monomers, oligomers and inclusion bodies...
  27. doi request reprint Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia
    Cecilia M Prele
    School of Anatomy and Human Biology, University of Western Australia, Crawley, Perth 6009, Australia
    Cardiovasc Pathol 21:17-27. 2012
    ..The aim of the present study was to assess the structural and ex vivo functional impacts of long-term cardiomyocyte-specific insulin-like growth factor-1 overexpression in hearts of transgenic αMHC-IGF-1 Ea mice...
  28. doi request reprint Changes in oxygen tension affect cardiac mitochondrial respiration rate via changes in the rate of mitochondrial hydrogen peroxide production
    Carla A Di Maria
    School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Australia
    J Mol Cell Cardiol 47:49-56. 2009
    ..These findings indicate that oxygen-dependent decreases in the rate of mitochondrial hydrogen peroxide production can decrease cardiac mitochondrial respiration...
  29. ncbi request reprint Taking the cell by stealth or storm? Protein transduction domains (PTDs) as versatile vectors for delivery
    Marie A Bogoyevitch
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley 6009, Australia
    DNA Cell Biol 21:879-94. 2002
    ..Recent examples of the range of potential applications are also discussed...
  30. ncbi request reprint Histone H4 histidine kinase displays the expression pattern of a liver oncodevelopmental marker
    Eiling Tan
    Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Carcinogenesis 25:2083-8. 2004
    ....
  31. ncbi request reprint Counting on mitogen-activated protein kinases--ERKs 3, 4, 5, 6, 7 and 8
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, WA 6009, Australia
    Cell Signal 16:1345-54. 2004
    ..It is clear from these studies that these additional ERKs show similarities to ERK1 and ERK2, but with some interesting differences that challenge the paradigm of the archetypical ERK1/2 MAPK pathway...
  32. ncbi request reprint Therapeutic promise of JNK ATP-noncompetitive inhibitors
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Trends Mol Med 11:232-9. 2005
    ....
  33. doi request reprint A novel retro-inverso peptide is a preferential JNK substrate-competitive inhibitor
    Kevin R W Ngoei
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    Int J Biochem Cell Biol 45:1939-50. 2013
    ..Thus, D-PYC98-TAT is a novel cell-permeable JNK inhibitor...
  34. pmc p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival
    Mengjie Hu
    Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, VIC 3010, Australia
    Biochem J 453:381-91. 2013
    ....
  35. doi request reprint Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction
    Kate L Weeks
    Baker IDI Heart and Diabetes Institute, University of Melbourne, Victoria 8008, Australia
    Circ Heart Fail 5:523-34. 2012
    ..Here, we assess whether phosphoinositide 3-kinase (PI3K) p110α is essential for mediating exercise-induced cardioprotection, and if so, whether its activation independent of exercise can restore function of the failing heart...
  36. doi request reprint Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle
    Miranda D Grounds
    School of Anatomy and Human Biology, The University of Western Australia, Crawley, Western Australia, Australia
    Clin Exp Pharmacol Physiol 35:846-51. 2008
    ....
  37. ncbi request reprint An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Australia
    Cardiovasc Res 63:208-16. 2004
    ..These beneficial effects of Epo should stimulate further research into the actions of Epo...
  38. ncbi request reprint Identification of the critical features of a small peptide inhibitor of JNK activity
    Renae K Barr
    Department of Biochemistry, University of Western Australia, Crawley 6009, Australia
    J Biol Chem 277:10987-97. 2002
    ..These studies thus define a small peptide inhibitor sequence of JNKs based on the JIP proteins...
  39. ncbi request reprint Proteomic analysis reveals different protein changes during endothelin-1- or leukemic inhibitory factor-induced hypertrophy of cardiomyocytes in vitro
    Tammy M Casey
    Department of Biochemistry and Molecular Biology, School of Biomedical and Chemical Sciences, University of Western Australia, Crawley, Western Australia 6009, Australia
    Mol Cell Proteomics 4:651-61. 2005
    ..This is consistent with the differences in morphologies noted as well as the different signaling pathways utilized by these different stimuli...
  40. ncbi request reprint Myoseverin disrupts sarcomeric organization in myocytes: an effect independent of microtubule assembly inhibition
    Dominic C H Ng
    Biochemistry and Molecular Biology, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Western Australia, Australia
    Cell Motil Cytoskeleton 65:40-58. 2008
    ..Sarcomere formation in cardiac myocytes therefore, does not appear to require an intact MT network and thus we conclude that a functional MT array appears to be dispensable for myofibrillogenesis...
  41. ncbi request reprint Small G-protein Rho is involved in the maintenance of cardiac myocyte morphology
    Haslett R Grounds
    Biochemistry and Molecular Biology, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Cell Biochem 95:529-42. 2005
    ..These results reveal a role for RhoA in the maintenance of normal myocyte morphology...
  42. ncbi request reprint The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, Crawley, Western Australia, Australia
    Bioessays 28:923-34. 2006
    ..These results emphasise the differences in the roles played by JNK isoforms in vivo and suggest that the design of JNK inhibitors for subsequent therapeutic uses may benefit from selective inhibition of individual JNK isoforms...
  43. pmc Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases
    Marie A Bogoyevitch
    Cell Signalling Laboratory, Biochemistry and Molecular Biology M310, School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia
    Microbiol Mol Biol Rev 70:1061-95. 2006
    ..Further characterization of the substrates of JNK should provide clearer explanations of the intracellular actions of the JNKs and may allow new avenues for targeting the JNK pathways with therapeutic agents downstream of JNK itself...
  44. ncbi request reprint Cardiac expression and subcellular localization of the p38 mitogen-activated protein kinase member, stress-activated protein kinase-3 (SAPK3)
    Naomi W Court
    Department of Biochemistry, University of Western Australia, Crawley, Western Australia 6009, Australia
    J Mol Cell Cardiol 34:413-26. 2002
    ..These differences between p38- alpha/ beta and SAPK3 probably reflect the specialized functions of SAPK3 and emphasize the need to evaluate SAPK3 upstream activators and downstream targets in the heart...