Research Topics
| Philippe BoeufSummaryAffiliation: University of Melbourne Country: Australia Publications
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Detail Information
Publications
Relevant assay to study the adhesion of Plasmodium falciparum-infected erythrocytes to the placental epitheliumPhilippe Boeuf
Department of Medicine RMH WH, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
PLoS ONE 6:e21126. 2011..This demonstrates the power of this assay to advance our understanding of epithelial adhesion of infected erythrocytes and in the design of intervention strategies...
Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transportPhilippe Boeuf
The University of Melbourne, Department of Medicine RMH, Parkville, Victoria, Australia
PLoS Pathog 9:e1003153. 2013..However, IV more profoundly compromises placental amino acid transport function, leading to FGR. Our study offers the first pathogenetic explanation for FGR in PM...
Placental hypoxia during placental malariaPhilippe Boeuf
Department of Medicine, University of Melbourne, Parkville, Victoria, Australia
J Infect Dis 197:757-65. 2008..We investigated whether parasite or monocyte infiltrates were associated with placental hypoxia, as a potential mechanism underlying malarial FGR...
Monocytes and macrophages in malaria: protection or pathology?Caroline Lin Lin Chua
The University of Melbourne, Department of Medicine Royal Melbourne Hospital, Parkville, Australia
Trends Parasitol 29:26-34. 2013..Knowledge of the factors influencing the balance between protection and pathology can assist in the design of therapeutics aimed at modulating monocyte and macrophage functions to improve outcomes...
Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulationAlexandra J Umbers
Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville Victoria 3050, Australia
J Infect Dis 203:561-9. 2011..We sought to determine whether placental malaria and related inflammation were associated with disturbances in the insulin-like growth factor (IGF) axis, a major regulator of fetal growth...
CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical usePhilippe Boeuf
Unité d Immunologie Moléculaire des Parasites, URA CNRS 2581, Département de Parasitologie et de Médecine Moléculaire, Institut Pasteur, 28 rue du Dr, Roux, 75724 Paris Cedex 15, France
BMC Immunol 6:5. 2005..The techniques currently used for "absolute quantification" of cytokine mRNA are based on a DNA standard curve and do not take into account the critical impact of RT efficiency...
