Philippe Boeuf

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc Relevant assay to study the adhesion of Plasmodium falciparum-infected erythrocytes to the placental epithelium
    Philippe Boeuf
    Department of Medicine RMH WH, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
    PLoS ONE 6:e21126. 2011
  2. pmc Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia
    Philippe S Boeuf
    Institut Pasteur, Unité d Immunologie Moléculaire des Parasites URA CNRS 2581, Paris, France
    Malar J 11:253. 2012
  3. pmc Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport
    Philippe Boeuf
    The University of Melbourne, Department of Medicine RMH, Parkville, Victoria, Australia
    PLoS Pathog 9:e1003153. 2013
  4. pmc Placental hypoxia during placental malaria
    Philippe Boeuf
    Department of Medicine, University of Melbourne, Parkville, Victoria, Australia
    J Infect Dis 197:757-65. 2008
  5. ncbi request reprint V beta profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
    Séverine Loizon
    Unité d Immunologie Moléculaire des Parasites, CNRS URA 2581, Departement de Parasitologie, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbes Infect 9:1252-9. 2007
  6. doi request reprint Monocytes and macrophages in malaria: protection or pathology?
    Caroline Lin Lin Chua
    The University of Melbourne, Department of Medicine Royal Melbourne Hospital, Parkville, Australia
    Trends Parasitol 29:26-34. 2013
  7. ncbi request reprint Insight into the pathogenesis of fetal growth restriction in placental malaria: decreased placental glucose transporter isoform 1 expression
    Upeksha P Chandrasiri
    Department of Medicine, University of Melbourne
    J Infect Dis 209:1663-7. 2014
  8. pmc Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulation
    Alexandra J Umbers
    Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville Victoria 3050, Australia
    J Infect Dis 203:561-9. 2011
  9. pmc Soluble CD163, a product of monocyte/macrophage activation, is inversely associated with haemoglobin levels in placental malaria
    Caroline Lin Lin Chua
    Department of Medicine Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 8:e64127. 2013
  10. pmc CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use
    Philippe Boeuf
    Unité d Immunologie Moléculaire des Parasites, URA CNRS 2581, Département de Parasitologie et de Médecine Moléculaire, Institut Pasteur, 28 rue du Dr, Roux, 75724 Paris Cedex 15, France
    BMC Immunol 6:5. 2005

Collaborators

Detail Information

Publications10

  1. pmc Relevant assay to study the adhesion of Plasmodium falciparum-infected erythrocytes to the placental epithelium
    Philippe Boeuf
    Department of Medicine RMH WH, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
    PLoS ONE 6:e21126. 2011
    ..This demonstrates the power of this assay to advance our understanding of epithelial adhesion of infected erythrocytes and in the design of intervention strategies...
  2. pmc Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia
    Philippe S Boeuf
    Institut Pasteur, Unité d Immunologie Moléculaire des Parasites URA CNRS 2581, Paris, France
    Malar J 11:253. 2012
    ..Monocytes and T cells are recognized as the main sources of TNF and IL-10 in vivo, but little is known about the activation status of those cells in SMA patients...
  3. pmc Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport
    Philippe Boeuf
    The University of Melbourne, Department of Medicine RMH, Parkville, Victoria, Australia
    PLoS Pathog 9:e1003153. 2013
    ..However, IV more profoundly compromises placental amino acid transport function, leading to FGR. Our study offers the first pathogenetic explanation for FGR in PM...
  4. pmc Placental hypoxia during placental malaria
    Philippe Boeuf
    Department of Medicine, University of Melbourne, Parkville, Victoria, Australia
    J Infect Dis 197:757-65. 2008
    ..We investigated whether parasite or monocyte infiltrates were associated with placental hypoxia, as a potential mechanism underlying malarial FGR...
  5. ncbi request reprint V beta profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
    Séverine Loizon
    Unité d Immunologie Moléculaire des Parasites, CNRS URA 2581, Departement de Parasitologie, Institut Pasteur, 25 rue du Dr Roux, 75724 Paris Cedex 15, France
    Microbes Infect 9:1252-9. 2007
    ..The significance of the reproducible increase of the CD4+V beta 21.3T cell subset deserves further investigations...
  6. doi request reprint Monocytes and macrophages in malaria: protection or pathology?
    Caroline Lin Lin Chua
    The University of Melbourne, Department of Medicine Royal Melbourne Hospital, Parkville, Australia
    Trends Parasitol 29:26-34. 2013
    ..Knowledge of the factors influencing the balance between protection and pathology can assist in the design of therapeutics aimed at modulating monocyte and macrophage functions to improve outcomes...
  7. ncbi request reprint Insight into the pathogenesis of fetal growth restriction in placental malaria: decreased placental glucose transporter isoform 1 expression
    Upeksha P Chandrasiri
    Department of Medicine, University of Melbourne
    J Infect Dis 209:1663-7. 2014
    ..43; P = .003) and positively with birth weight (r = 0.28; P = .06). These findings suggest that intervillositis, more than placental malaria per se, might cause fetal growth restriction, through impaired transplacental glucose transport. ..
  8. pmc Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulation
    Alexandra J Umbers
    Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Royal Parade, Parkville Victoria 3050, Australia
    J Infect Dis 203:561-9. 2011
    ..We sought to determine whether placental malaria and related inflammation were associated with disturbances in the insulin-like growth factor (IGF) axis, a major regulator of fetal growth...
  9. pmc Soluble CD163, a product of monocyte/macrophage activation, is inversely associated with haemoglobin levels in placental malaria
    Caroline Lin Lin Chua
    Department of Medicine Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 8:e64127. 2013
    ..259, p = 0.0001). These inverse relationships suggest a potential role for monocyte/macrophage activation in the pathogenesis of malaria in pregnancy, particularly in relation to malaria-associated anaemia...
  10. pmc CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use
    Philippe Boeuf
    Unité d Immunologie Moléculaire des Parasites, URA CNRS 2581, Département de Parasitologie et de Médecine Moléculaire, Institut Pasteur, 28 rue du Dr, Roux, 75724 Paris Cedex 15, France
    BMC Immunol 6:5. 2005
    ..The techniques currently used for "absolute quantification" of cytokine mRNA are based on a DNA standard curve and do not take into account the critical impact of RT efficiency...