Y V Bobryshev

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. ncbi Expression of heat shock protein-70 by dendritic cells in the arterial intima and its potential significance in atherogenesis
    Yuri V Bobryshev
    Surgical Professorial Unit, University of New South Wales, St Vincent s Hospital, Sydney, Australia
    J Vasc Surg 35:368-75. 2002
  2. ncbi Pluronic block copolymers inhibit low density lipoprotein self-association
    Alexandra A Melnichenko
    Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia
    Lipids 47:995-1000. 2012
  3. pmc Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease
    Igor A Sobenin
    Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Russian Ministry of Health and Social Care, Moscow, Russian Federation
    PLoS ONE 7:e46573. 2012
  4. pmc Association of mitochondrial genetic variation with carotid atherosclerosis
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, Moscow, Russia
    PLoS ONE 8:e68070. 2013
  5. pmc Mitochondrial mutations are associated with atherosclerotic lesions in the human aorta
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, 121552 Moscow, Russia
    Clin Dev Immunol 2012:832464. 2012
  6. pmc Mitochondrial dysfunction and mitochondrial DNA mutations in atherosclerotic complications in diabetes
    Dimitry A Chistiakov
    Dimitry A Chistiakov, Igor A Sobenin, Department of Medical Nanobiotechnology, Pirogov Russian State Medical University, 117997 Moscow, Russia
    World J Cardiol 4:148-56. 2012
  7. doi Correlation between lipid deposition, immune-inflammatory cell content and MHC class II expression in diffuse intimal thickening of the human aorta
    Yuri V Bobryshev
    Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Moscow, Russia
    Atherosclerosis 219:171-83. 2011
  8. pmc Lipid regulators during atherogenesis: expression of LXR, PPAR, and SREBP mRNA in the human aorta
    Tatyana A Shchelkunova
    Biological Faculty, Lomonosov Moscow State University, Moscow, Russia
    PLoS ONE 8:e63374. 2013
  9. doi Changes of mitochondria in atherosclerosis: possible determinant in the pathogenesis of the disease
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, 121552 Moscow, Russia
    Atherosclerosis 227:283-8. 2013
  10. doi Changes of lysosomes in the earliest stages of the development of atherosclerosis
    Yuri V Bobryshev
    Faculty of Medicine, School of Medical Sciences, University of New South Wales, Kensington, NSW, Australia
    J Cell Mol Med 17:626-35. 2013

Collaborators

Detail Information

Publications62

  1. ncbi Expression of heat shock protein-70 by dendritic cells in the arterial intima and its potential significance in atherogenesis
    Yuri V Bobryshev
    Surgical Professorial Unit, University of New South Wales, St Vincent s Hospital, Sydney, Australia
    J Vasc Surg 35:368-75. 2002
    ..Dendritic cells are the key cells in the initiation and regulation of immune responses. This study examined whether HSP70 is overexpressed by dendritic cells in atherosclerotic lesions...
  2. ncbi Pluronic block copolymers inhibit low density lipoprotein self-association
    Alexandra A Melnichenko
    Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia
    Lipids 47:995-1000. 2012
    ..The possibility of modulating the aggregation of LDL by various Pluronic copolymers can be regarded as a prerequisite in the creation of new types of anti-atherosclerotic drugs...
  3. pmc Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease
    Igor A Sobenin
    Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Russian Ministry of Health and Social Care, Moscow, Russian Federation
    PLoS ONE 7:e46573. 2012
    ....
  4. pmc Association of mitochondrial genetic variation with carotid atherosclerosis
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, Moscow, Russia
    PLoS ONE 8:e68070. 2013
    ..001) associated with both the severity of carotid atherosclerosis and the presence of CHD. These findings indicate that somatic mitochondrial mutations have a role in the development of atherosclerosis. ..
  5. pmc Mitochondrial mutations are associated with atherosclerotic lesions in the human aorta
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, 121552 Moscow, Russia
    Clin Dev Immunol 2012:832464. 2012
    ..These mutations were A1555G, C3256T, T3336C, G13513A, and G15059A. Thus, it was demonstrated that at least five mitochondrial mutations occurring in MT-RNR1, MT-TL1, MT-ND2, MT-ND5, and MT-CYB genes are associated with atherosclerosis...
  6. pmc Mitochondrial dysfunction and mitochondrial DNA mutations in atherosclerotic complications in diabetes
    Dimitry A Chistiakov
    Dimitry A Chistiakov, Igor A Sobenin, Department of Medical Nanobiotechnology, Pirogov Russian State Medical University, 117997 Moscow, Russia
    World J Cardiol 4:148-56. 2012
    ....
  7. doi Correlation between lipid deposition, immune-inflammatory cell content and MHC class II expression in diffuse intimal thickening of the human aorta
    Yuri V Bobryshev
    Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Moscow, Russia
    Atherosclerosis 219:171-83. 2011
    ....
  8. pmc Lipid regulators during atherogenesis: expression of LXR, PPAR, and SREBP mRNA in the human aorta
    Tatyana A Shchelkunova
    Biological Faculty, Lomonosov Moscow State University, Moscow, Russia
    PLoS ONE 8:e63374. 2013
    ..We speculate that the observed changes in mRNAs expression and coupling reflect shifts in lipid ligands availability and cellular composition in the course of atherosclerosis progression...
  9. doi Changes of mitochondria in atherosclerosis: possible determinant in the pathogenesis of the disease
    Igor A Sobenin
    Russian Cardiology Research and Production Complex, 121552 Moscow, Russia
    Atherosclerosis 227:283-8. 2013
    ..The mitochondrial mutations observed in our study should encourage further exploration of the concept that mitochondrial DNA heteroplasmy might be used as a biomarker of atherogenesis...
  10. doi Changes of lysosomes in the earliest stages of the development of atherosclerosis
    Yuri V Bobryshev
    Faculty of Medicine, School of Medical Sciences, University of New South Wales, Kensington, NSW, Australia
    J Cell Mol Med 17:626-35. 2013
    ..The study reinforces a view that changes occurring in lysosomes play a role in atherogenesis from the very earlier stages of the disease...
  11. ncbi Anti-atherosclerotic therapy based on botanicals
    Alexander N Orekhov
    Institute for Atherosclerosis Research of Skolkovo Innovative Center, Moscow, Russia
    Recent Pat Cardiovasc Drug Discov 8:56-66. 2013
    ....
  12. ncbi Knowledge of colorectal cancer screening among young Malaysians
    Redhwan Ahmed Al-Naggar
    Population Health and Preventive Medicine Department, Faculty of Medicine, UITM, Malaysia
    Asian Pac J Cancer Prev 14:1969-74. 2013
    ..The present study results indicate that education campaigns about colorectal cancer should be promoted...
  13. ncbi Prevalence of cigarette smoking and associated factors among secondary school teachers in Malaysia
    Redhwan A Al-Naggar
    Community Medicine Department, International Medical School, Management and Science University, Shah Alam, Malaysia
    Asian Pac J Cancer Prev 13:5539-43. 2012
    ..The smoking prevalence in Malaysia is high, especially among men and adolescents. This study aimed to determine the prevalence and associated factors towards cigarette smoking among school teachers in Malaysia...
  14. ncbi Practice and barriers of mammography among Malaysian women in the general population
    Redhwan A Al-Naggar
    Community Medicine Department, International Medical School, Management and Science University, Kuala Lumpur, Malaysia
    Asian Pac J Cancer Prev 13:3595-600. 2012
    ..The objective of this study was to determine the practice and barriers of mammography and associated factors among Malaysian women in the general population...
  15. doi Increased shedding of microvesicles from intimal smooth muscle cells in athero-prone areas of the human aorta: implications for understanding of the predisease stage
    Yuri V Bobryshev
    Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Moscow, Russia
    Pathobiology 80:24-31. 2013
    ..This study evaluated whether a change in the content of matrix microvesicles might occur at the preatherosclerotic stage...
  16. doi Structural alterations of the mucosa stroma in the Barrett's esophagus metaplasia-dysplasia-adenocarcinoma sequence
    Yuri V Bobryshev
    St Vincent s Centre for Applied Medical Research and Department of Surgery, St Vincent s Hospital Sydney, University of New South Wales, Sydney, Australia
    J Gastroenterol Hepatol 27:1498-504. 2012
    ..The present study examined the structural characteristics and alterations of the extracellular matrix of the mucosa stroma in the Barrett's esophagus metaplasia-dysplasia-adenocarcinoma sequence...
  17. doi Widespread distribution of HLA-DR-expressing cells in macroscopically undiseased intima of the human aorta: a possible role in surveillance and maintenance of vascular homeostasis
    Yuri V Bobryshev
    Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Moscow, Russia
    Immunobiology 217:558-68. 2012
    ..We speculate that a widespread distribution of HLA-DR-expressing cells in the intima of normal human aorta might play a role in the surveillance and maintenance of vascular homeostasis...
  18. doi Musashi-1 expression in atherosclerotic arteries and its relevance to the origin of arterial smooth muscle cells: histopathological findings and speculations
    Yuri V Bobryshev
    Faculty of Medicine, University of New South Wales, Kensington, NSW 2052, Australia
    Atherosclerosis 215:355-65. 2011
    ....
  19. doi Expression of C1q complement component in Barrett's esophagus and esophageal adenocarcinoma
    Yuri V Bobryshev
    Faculty of Medicine, University of New South Wales, Kensington, NSW 2052, Australia
    J Gastrointest Surg 14:1207-13. 2010
    ..The present study investigated whether C1q is expressed in Barrett's esophagus and esophageal adenocarcinoma and, if so, whether its expression is associated with dendritic cells...
  20. ncbi Chlamydia pneumoniae in foci of "early" calcification of the tunica media in arteriosclerotic arteries: an incidental presence?
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, Sydney, New South Wales, Australia
    Am J Physiol Heart Circ Physiol 290:H1510-9. 2006
    ..The findings offer a new hypothesis of arterial calcification: they suggest that C. pneumoniae infection of medial SMCs may be associated with the pathophysiological events of arteriosclerotic calcification of the tunica media...
  21. doi Dendritic cells and their role in atherogenesis
    Yuri V Bobryshev
    Faculty of Medicine, SOMS, University of New South Wales, Kensington, NSW, Australia
    Lab Invest 90:970-84. 2010
    ....
  22. doi Dendritic cell-associated immune inflammation of cardiac mucosa: a possible factor in the formation of Barrett's esophagus
    Yuri V Bobryshev
    Department of Surgery and Centre for Immunology, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    J Gastrointest Surg 13:442-50. 2009
    ..The present study was undertaken to examine the presence and distribution of immune-inflammatory cells in cardiac mucosa, specifically focusing on dendritic cells because of their importance as regulators of immune reactions...
  23. ncbi Are calcifying matrix vesicles in atherosclerotic lesions of cellular origin?
    Yuri V Bobryshev
    School of Medical Sciences, Faculty of Medicine, University of New South Wales, Kensington, NSW, 2052, Australia
    Basic Res Cardiol 102:133-43. 2007
    ....
  24. doi Spatial distribution of osteoblast-specific transcription factor Cbfa1 and bone formation in atherosclerotic arteries
    Yuri V Bobryshev
    Faculty of Medicine, University of New South Wales, Kensington, NSW 2052, Australia
    Cell Tissue Res 333:225-35. 2008
    ..This study has also revealed that Cbfa1-expressing cells contain alpha-smooth muscle actin and myofilaments, indicating their relationship with arterial smooth muscle cells...
  25. doi Matrix vesicles in the fibrous cap of atherosclerotic plaque: possible contribution to plaque rupture
    Y V Bobryshev
    Faculty of Medicine, University of New South Wales, Kensington NSW, Australia
    J Cell Mol Med 12:2073-82. 2008
    ..705+/-0.436 versus 5.322+/-0494; P= 0.0474). The findings reinforce a view that the texture of the extracellular matrix in the thinning fibrous cap of atherosclerotic plaque is altered and this might contribute to plaque destabilization...
  26. ncbi Intracellular localization of oxidized low-density lipoproteins in atherosclerotic plaque cells revealed by electron microscopy combined with laser capture microdissection
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, Sydney, Darlinghurst, NSW 2010, Australia
    J Histochem Cytochem 53:793-7. 2005
    ....
  27. doi Amalgamation of Chlamydia pneumoniae inclusions with lipid droplets in foam cells in human atherosclerotic plaque
    Yuri V Bobryshev
    Faculty of Medicine, University of New South Wales, Kensington, NSW, Australia
    Virchows Arch 453:69-77. 2008
    ..pneumoniae-infected foam cells contained a large number of oxidized low-density lipoproteins. The observations provide support to the hypothesis that C. pneumoniae could affect foam cell formation in human atherosclerosis...
  28. ncbi Monocyte recruitment and foam cell formation in atherosclerosis
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, 234 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Micron 37:208-22. 2006
    ..This review highlights some aspects of monocyte recruitment and foam cell formation in atherosclerosis...
  29. ncbi Dendritic cells in atherosclerosis: current status of the problem and clinical relevance
    Yuri V Bobryshev
    Surgical Professorial Unit, Level 5, DeLacy Building, St Vincent s Hospital Sydney, University of New South Wales, Darlinghurst, New South Wales 2010, Australia
    Eur Heart J 26:1700-4. 2005
    ..Dyslipidaemia systemically alters DC function and recent findings suggest that DCs play a role in plaque destabilization. This review summarizes the current status of the problem...
  30. ncbi Transdifferentiation of smooth muscle cells into chondrocytes in atherosclerotic arteries in situ: implications for diffuse intimal calcification
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital Sydney, University of New South Wales, Darlinghurst, NSW 2010, Australia
    J Pathol 205:641-50. 2005
    ..Similar processes were found to occur in atherosclerotic-like lesions in apo-E-deficient mice. These observations suggest that transdifferentiation of smooth muscle cells into chondrocytes contributes to atherosclerotic calcification...
  31. ncbi CD40 co-stimulatory molecule expression by dendritic cells in primary atherosclerotic lesions in carotid arteries and in stenotic saphenous vein coronary artery grafts
    J Ozmen
    Surgical Professorial Unit, St. Vincent's Hospital, University of, New South Wales, Australia
    Cardiovasc Surg 9:329-33. 2001
    ..The expression of CD40 molecule on the dendritic cells may be important in regulating T cell responses within atherosclerotic plaques and stenotic vein grafts...
  32. ncbi Immunohistochemical and ultrastructural evidence that dendritic cells infiltrate stenotic aortocoronary saphenous vein bypass grafts
    S M Cherian
    Surgical Professorial Unit, St Vincent's Hospital, University of New South Wales, Victoria Street, Level 17 O'Brien Building, Darlinhurst, NSW 2010, Australia
    Cardiovasc Surg 9:194-200. 2001
    ..Dendritic cells may be responsible for antigen presentation and modulation of immune reactions in accelerated graft atherosclerosis through their interaction with T-lymphocytes...
  33. ncbi S100A8 and S100A9 in human arterial wall. Implications for atherogenesis
    Michelle M McCormick
    School of Medical Sciences, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    J Biol Chem 280:41521-9. 2005
    ..S100A8 and S100A9 in atherosclerotic plaque and calcifying matrix vesicles may significantly influence redox- and Ca2+-dependent processes during atherogenesis and its chronic complications, particularly dystrophic calcification...
  34. ncbi Colonisation of prosthetic grafts by immunocompetent cells in a sheep model
    Y V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, University of New South Wales, Sydney, NSW 2010, Australia
    Cardiovasc Surg 9:166-76. 2001
    ..These observations demonstrate that immunocompetent cells colonise the synthetic matrix of grafts and accumulate in the perigraft tissue, but inflammatory responses vary in different graft types...
  35. ncbi Identification of dendritic cells in ePTFE grafts explanted from humans
    S J Inder
    Surgical Professorial Unit, St Vincent s Hospital, NSW 2010, Sydney, Australia
    Cardiovasc Surg 8:265-73. 2000
    ..Based on these observations, we speculate that dendritic cells may be involved in the immuno-inflammatory responses following the implantation of synthetic vascular prostheses through their interaction with T-lymphocytes...
  36. ncbi Expression of vascular endothelial growth factor in aortocoronary saphenous vein bypass grafts
    Y V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, University of New South Wales, NSW 2010, Darlinghurst, Australia
    Cardiovasc Surg 9:492-8. 2001
    ....
  37. ncbi Phenotype determination of anti-GM3 positive cells in atherosclerotic lesions of the human aorta. Hypothetical role of ganglioside GM3 in foam cell formation
    Y V Bobryshev
    Surgical Professional Unit, St. Vincent's Hospital, University of New South Wales, Sydney, Australia
    Biochim Biophys Acta 1535:87-99. 2001
    ..We speculate that extracellularly localised GM3 might affect the differentiation and modification of intimal cells in atherosclerotic lesions...
  38. ncbi Evidence that dendritic cells infiltrate atherosclerotic lesions in apolipoprotein E-deficient mice
    Y V Bobryshev
    Surgical Professorial Unit, University of New South Wales, St Vincent s Hospital, Sydney, Australia
    Histol Histopathol 16:801-8. 2001
    ..Finding dendritic cells infiltrating atherosclerotic lesions in apoE-deficient mice offers the possibility of investigating the migratory routes of dendritic cells and their involvement in T-cell activation...
  39. doi Dendritic cells in Barrett's esophagus and esophageal adenocarcinoma
    Yuri V Bobryshev
    Department of Surgery and Centre for Immunology, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    J Gastrointest Surg 13:44-53. 2009
    ..A comprehensive literature search failed to find any report of the presence of dendritic cells in Barrett's intestinal metaplasia and esophageal adenocarcinoma and this prompted our study...
  40. ncbi Ultrastructural identification of cells with dendritic cell appearance in atherosclerotic aorta of apolipoprotein E deficient mice
    Y V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, Darlinghurst, NSW, Australia
    J Submicrosc Cytol Pathol 31:527-31. 1999
    ..The present observations suggest that dendritic cells are involved in apoE deficient mouse atherosclerosis. ApoE deficient mice might be a useful model for investigating functions of dendritic cells in atherogenesis...
  41. ncbi Identification of dendritic cells in aortic atherosclerotic lesions in rats with diet-induced hypercholesterolaemia
    J Ozmen
    Surgical Professorial Unit, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    Histol Histopathol 17:223-37. 2002
    ..The presence of DCs in this model of experimental atherogenesis could provide a new approach to investigating the function of DCs and may help clarify the immune-inflammatory mechanisms underlying atherosclerosis...
  42. doi Expression of the putative stem cell marker Musashi-1 in Barrett's esophagus and esophageal adenocarcinoma
    Y V Bobryshev
    St Vincent s Centre for Applied Medical Research and Department of Surgery, St Vincent s Hospital, University of New South Wales, 438 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Dis Esophagus 23:580-9. 2010
    ..We speculate that immune inflammation occurring in Barrett's esophagus alters the mucosal microenvironment in a manner which is favorable to the activation of dormant stem cells...
  43. ncbi Subset of cells immunopositive for neurokinin-1 receptor identified as arterial interstitial cells of Cajal in human large arteries
    Yuri V Bobryshev
    Surgical Professorial Unit Level 5, St Vincent s Hospital, DeLacy Building, Darlinghurst, NSW, 2010, Australia
    Cell Tissue Res 321:45-55. 2005
    ..The functional significance of the arterial interstitial cells of Cajal and their possible involvement in atherosclerosis and other vascular diseases need clarification...
  44. ncbi Expression of GM3 synthase in human atherosclerotic lesions
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital Sydney, University of New South Wales, Darlinghurst, NSW 2010, Australia
    Atherosclerosis 184:63-71. 2006
    ..The findings of the present study indicate that, at least partially, excessive amounts of GM3 in atherosclerotic lesions can be synthesized by macrophages and dendritic cells directly within the arterial wall...
  45. ncbi Expression of apoptosis-related proteins and structural features of cell death in explanted aortocoronary saphenous vein bypass grafts
    A Y Wang
    Surgical Professorial Unit, St Vincent's Hospital, Victoria Street, Darlinghurst, NSW 2010, Sydney, Australia
    Cardiovasc Surg 9:319-28. 2001
    ..An imbalance between DNA fragmentation and DNA synthesis may contribute to graft instability and failure...
  46. doi Peculiarities of cell composition and cell proliferation in different type atherosclerotic lesions in carotid and coronary arteries
    A N Orekhov
    Institute for Atherosclerosis Research, Russian Academy of Natural Sciences, Moscow, Russia
    Atherosclerosis 212:436-43. 2010
    ....
  47. ncbi Ultrastructural recognition of dendritic cells in the intimal lesions of aortas of chickens affected with Marek's disease
    Y V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, Darlinghurst, Australia
    J Submicrosc Cytol Pathol 31:179-85. 1999
    ..Our observations show that dendritic cells are present in the aortic lesions of Marek's disease and are presumably involved in related immune mechanisms...
  48. ncbi Induction of the transcriptional repressor Yin Yang-1 by vascular cell injury. Autocrine/paracrine role of endogenous fibroblast growth factor-2
    F S Santiago
    Center for Thrombosis and Vascular Research, The University of New South Wales, Sydney, New South Wales 2052, Australia
    J Biol Chem 276:41143-9. 2001
    ....
  49. ncbi Hallmarks of atherosclerotic lesion development with special reference to immune inflammatory mechanisms
    R S A Lord
    Surgical Professorial Unit, St Vincent s Hospital, University of New South Wales, Sydney, NSW, Australia
    Cardiovasc Surg 10:405-14. 2002
    ..Despite increasing acknowledgment that immune-inflammatory processes participate in atherogenesis, the immune mechanisms remain incompletely defined...
  50. ncbi c-Jun regulates vascular smooth muscle cell growth and neointima formation after arterial injury. Inhibition by a novel DNA enzyme targeting c-Jun
    Levon M Khachigian
    Centre for Thrombosis and Vascular Research, Department of Pathology, University of New South Wales, Sydney, New South Wales 2052, Australia
    J Biol Chem 277:22985-91. 2002
    ..These studies demonstrate the positive influence on neointima formation by c-Jun and the therapeutic potential of a DNAzyme controlling its expression...
  51. ncbi Detection of Chlamydophila pneumoniae in dendritic cells in atherosclerotic lesions
    Yuri V Bobryshev
    Surgical Professional Unit, St Vincent s Hospital, University of New South Wales, Sydney, Australia
    Atherosclerosis 173:185-95. 2004
    ..pneumoniae might infect DCs within the atherosclerotic intima but whether the presence of C. pneumoniae in DCs affects the intensity of immune reactions in atherosclerosis needs further clarification...
  52. pmc Peroxide-inducible Ets-1 mediates platelet-derived growth factor receptor-alpha gene transcription in vascular smooth muscle cells
    Michelle R Bonello
    Centre for Vascular Research, Department of Pathology, The University of New South Wales, Sydney, NSW 2052, Australia
    Am J Pathol 167:1149-59. 2005
    ..These studies identify a functional Ets motif in the PDGF-Ralpha promoter that plays a pivotal role in agonist-inducible PDGF-Ralpha transcription...
  53. ncbi Calcification of elastic fibers in human atherosclerotic plaque
    Yuri V Bobryshev
    Surgical Professorial Unit, Level 5, DeLacy Building, St Vincent s Hospital Sydney, University of New South Wales, Darlinghurst NSW 2010, Australia
    Atherosclerosis 180:293-303. 2005
    ..Type II calcification was widespread throughout the plaque matrix while type I calcification occurred only in the deep portions of plaques...
  54. ncbi Vascular-associated lymphoid tissue (VALT) involvement in aortic aneurysm
    Y V Bobryshev
    Surgical Professorial Unit, Level 17, O Brien Building, St Vincent s Hospital, University of New South Wales, Darlinghurst, NSW, 2010, Sydney, Australia
    Atherosclerosis 154:15-21. 2001
    ..The formation of lymphoid follicles and lymph node-like structures in the adventitia suggests that VALT might locally serve the entire complex of both cellular and humoral immune responses in the aneurysmal wall...
  55. ncbi Co-accumulation of dendritic cells and natural killer T cells within rupture-prone regions in human atherosclerotic plaques
    Yuri V Bobryshev
    Surgical Professorial Unit, St Vincent s Hospital, Sydney, Darlinghurst, NSW 2010 Australia
    J Histochem Cytochem 53:781-5. 2005
    ..We found that NKT cells do accumulate in rupture-prone shoulders of atherosclerotic plaques and observed direct contacts of dendritic cells with NKT cells in rupture-prone regions of plaque...
  56. doi Pleiotropic roles of S100A12 in coronary atherosclerotic plaque formation and rupture
    Jesse Goyette
    Centre for Infection and Inflammation Research, University of New South Wales, Sydney, Australia
    J Immunol 183:593-603. 2009
    ..S100A12 may represent a new marker of this disease and may protect advanced atherosclerotic lesions from rupture by inhibiting excessive MMP-2 and MMP-9 activities by sequestering Zn(2+)...
  57. ncbi Identification of natural killer cells in human atherosclerotic plaque
    Yuri V Bobryshev
    Atherosclerosis 180:423-7. 2005
  58. ncbi Dendritic cells in the arterial wall express C1q: potential significance in atherogenesis
    Weiping Cao
    National University Medical Institutes, National University of Singapore, Blk MD11, 02 01 10 Medical Drive, Singapore 117597, Singapore
    Cardiovasc Res 60:175-86. 2003
    ..Because DCs accumulating within atherosclerotic lesions might originate from monocytes that infiltrate the intima from very early stages of atherosclerosis, C1q expression was also examined in monocyte-derived DCs in vitro...
  59. pmc Human immunodeficiency virus impairs reverse cholesterol transport from macrophages
    Zahedi Mujawar
    The George Washington University, Washington, District of Columbia, USA
    PLoS Biol 4:e365. 2006
    ....
  60. ncbi Induction of apoptosis in vascular cells by plasminogen activator inhibitor-1 and high molecular weight kininogen correlates with their anti-adhesive properties
    Nadia Al-Fakhri
    Institute of Clinical Chemistry and Pathobiochemistry, Justus Liebig University, Gaffkystrasse 11, D 35392 Giessen, Germany
    Biol Chem 384:423-35. 2003
    ..Co-distribution of apoptosis with plasminogen activation system components in atherosclerosis exemplifies the significance of anti-adhesive mechanisms and apoptosis for tissue remodeling, such as in neointima development...
  61. ncbi Increased expression of disintegrin-metalloproteinases ADAM-15 and ADAM-9 following upregulation of integrins alpha5beta1 and alphavbeta3 in atherosclerosis
    Nadia Al-Fakhri
    Institute of Clinical Chemistry and Pathobiochemistry, Justus Liebig University, Giessen, Germany
    J Cell Biochem 89:808-23. 2003
    ....
  62. doi TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor
    Mary M Kavurma
    Division of Cardiovascular Medicine, University of Cambridge, Box 110, Addenbrooke s Hospital, Cambridge CB2 2QQ, United Kingdom
    J Biol Chem 283:7754-62. 2008
    ..Thus, TRAIL may play an important role in atherosclerosis by regulating IGF1R expression in VSMC in an NF-kappaB-dependent manner...