Mark A T Blaskovich
Affiliation: University of Queensland
Kavanagh A, Ramu S, Gong Y, Cooper M, Blaskovich M. Effects of Microplate Type and Broth Additives on Microdilution MIC Susceptibility Assays. Antimicrob Agents Chemother. 2019;63: pubmed publisher
..Microtiter plate types and any additives should be specified when reporting broth dilution MIC values, as results can vary dramatically for some classes of antibiotics. ..
Gallardo Godoy A, Hansford K, Muldoon C, Becker B, Elliott A, Huang J, et al
. Structure-Function Studies of Polymyxin B Lipononapeptides. Molecules. 2019;24: pubmed publisher
..The strategy may aid in the design of next generation polymyxins. ..
Phetsang W, Blaskovich M, Butler M, Huang J, Zuegg J, Mamidyala S, et al
. An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants. Bioorg Med Chem. 2014;22:4490-8 pubmed publisher
..The fluorescent probes were successfully used to image Gram-positive bacteria using confocal microscopy. ..
Blaskovich M, Hansford K, Gong Y, Butler M, Muldoon C, Huang J, et al
. Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nat Commun. 2018;9:22 pubmed publisher
Blaskovich M, Butler M, Cooper M. Polishing the tarnished silver bullet: the quest for new antibiotics. Essays Biochem. 2017;61:103-114 pubmed publisher
..The question remains as to how to achieve this goal. This review will examine the different strategies being applied to discover new antibiotics. ..
Becker B, Butler M, Hansford K, Gallardo Godoy A, Elliott A, Huang J, et al
. Synthesis of octapeptin C4 and biological profiling against NDM-1 and polymyxin-resistant bacteria. Bioorg Med Chem Lett. 2017;27:2407-2409 pubmed publisher
..The linear analogue of octapeptin C4 was also prepared, which showed reduced activity. ..