Michele D Binder

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi TAM receptor signalling and demyelination
    Michele D Binder
    Florey Neuroscience Institutes and Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:277-87. 2009
  2. ncbi Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination
    Michele D Binder
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 6:e17727. 2011
  3. ncbi Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination
    Michele D Binder
    Howard Florey Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    J Neurosci 28:5195-206. 2008
  4. ncbi Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair
    Mark P Marriott
    Howard Florey Institute, The University of Melbourne, Victoria, Australia
    Glia 56:686-98. 2008
  5. ncbi Oligodendrocyte positioning in cerebral cortex is independent of projection neuron layering
    Seong Seng Tan
    Florey Neurosciences Institute and Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia
    Glia 57:1024-30. 2009
  6. ncbi Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
  7. ncbi Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility
    Gerry Z M Ma
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 6:e16964. 2011
  8. ncbi Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice
    Rachel A Hill
    Behavioral Neuroscience Laboratory, Mental Health Research Institute, Parkville, Victoria, Australia 3052
    Hippocampus 21:434-45. 2011

Collaborators

Detail Information

Publications8

  1. ncbi TAM receptor signalling and demyelination
    Michele D Binder
    Florey Neuroscience Institutes and Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:277-87. 2009
    ..A current challenge in this field is to expand our understanding of TAM receptor signalling from rodent models of central demyelination to human disease...
  2. ncbi Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination
    Michele D Binder
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 6:e17727. 2011
    ..These findings establish Gas6 as an important regulator of both CNS demyelination and remyelination...
  3. ncbi Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination
    Michele D Binder
    Howard Florey Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    J Neurosci 28:5195-206. 2008
    ..Therefore, TAM receptor activation and regulation can independently influence both oligodendrocyte survival and the microglial response after CNS damage...
  4. ncbi Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair
    Mark P Marriott
    Howard Florey Institute, The University of Melbourne, Victoria, Australia
    Glia 56:686-98. 2008
    ..Thus endogenous LIF receptor signaling is not only protective of oligodendrocytes but can also enhance remyelination, and exogenous LIF has therapeutic potential in limiting the consequences of oligodendrocyte damage...
  5. ncbi Oligodendrocyte positioning in cerebral cortex is independent of projection neuron layering
    Seong Seng Tan
    Florey Neurosciences Institute and Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia
    Glia 57:1024-30. 2009
    ..We conclude that oligodendrocyte positioning is not linked to the layer positions of V/VI projection neurons...
  6. ncbi Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
    ....
  7. ncbi Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility
    Gerry Z M Ma
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 6:e16964. 2011
    ..All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility...
  8. ncbi Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice
    Rachel A Hill
    Behavioral Neuroscience Laboratory, Mental Health Research Institute, Parkville, Victoria, Australia 3052
    Hippocampus 21:434-45. 2011
    ..05). In conclusion, loss of 5-HT(2C) receptor expression leads to a marked and selective increase in levels of the mature form of BDNF in the hippocampus. Despite this marked increase, 5-HT(2C) KO show only subtle behavioral changes...