Michele D Binder

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint TAM receptor signalling and demyelination
    Michele D Binder
    Florey Neuroscience Institutes and Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:277-87. 2009
  2. pmc Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination
    Michele D Binder
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 6:e17727. 2011
  3. pmc Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination
    Michele D Binder
    Howard Florey Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    J Neurosci 28:5195-206. 2008
  4. doi request reprint Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain
    Rachel A Hill
    Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia
    Biochim Biophys Acta 1842:2126-35. 2014
  5. doi request reprint Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor
    Melissa M Gresle
    Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Australia Department of Medicine, University of Melbourne, Australia
    Glia 63:1005-20. 2015
  6. doi request reprint Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair
    Mark P Marriott
    Howard Florey Institute, The University of Melbourne, Victoria, Australia
    Glia 56:686-98. 2008
  7. doi request reprint Oligodendrocyte positioning in cerebral cortex is independent of projection neuron layering
    Seong Seng Tan
    Florey Neurosciences Institute and Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia
    Glia 57:1024-30. 2009
  8. doi request reprint Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
  9. doi request reprint Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling
    Rachel A Hill
    Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia
    Hippocampus 24:1197-211. 2014
  10. pmc Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility
    Gerry Z M Ma
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 6:e16964. 2011

Collaborators

Detail Information

Publications11

  1. doi request reprint TAM receptor signalling and demyelination
    Michele D Binder
    Florey Neuroscience Institutes and Centre for Neuroscience, The University of Melbourne, Parkville, Vic, Australia
    Neurosignals 17:277-87. 2009
    ..A current challenge in this field is to expand our understanding of TAM receptor signalling from rodent models of central demyelination to human disease...
  2. pmc Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination
    Michele D Binder
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 6:e17727. 2011
    ..These findings establish Gas6 as an important regulator of both CNS demyelination and remyelination...
  3. pmc Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination
    Michele D Binder
    Howard Florey Institute, University of Melbourne, Parkville, Victoria 3010, Australia
    J Neurosci 28:5195-206. 2008
    ..Therefore, TAM receptor activation and regulation can independently influence both oligodendrocyte survival and the microglial response after CNS damage...
  4. doi request reprint Long-term effects of combined neonatal and adolescent stress on brain-derived neurotrophic factor and dopamine receptor expression in the rat forebrain
    Rachel A Hill
    Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia
    Biochim Biophys Acta 1842:2126-35. 2014
    ..These results elucidate the long-term effects of 'two hit' developmental stress on behaviour. ..
  5. doi request reprint Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor
    Melissa M Gresle
    Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Australia Department of Medicine, University of Melbourne, Australia
    Glia 63:1005-20. 2015
    ..These findings suggest a potential role for the use of galanin agonists in the treatment of human demyelinating diseases. GLIA 2015;63:1005-1020. ..
  6. doi request reprint Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair
    Mark P Marriott
    Howard Florey Institute, The University of Melbourne, Victoria, Australia
    Glia 56:686-98. 2008
    ..Thus endogenous LIF receptor signaling is not only protective of oligodendrocytes but can also enhance remyelination, and exogenous LIF has therapeutic potential in limiting the consequences of oligodendrocyte damage...
  7. doi request reprint Oligodendrocyte positioning in cerebral cortex is independent of projection neuron layering
    Seong Seng Tan
    Florey Neurosciences Institute and Centre for Neuroscience, The University of Melbourne, Parkville, Victoria, Australia
    Glia 57:1024-30. 2009
    ..We conclude that oligodendrocyte positioning is not linked to the layer positions of V/VI projection neurons...
  8. doi request reprint Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS
    Tobias D Merson
    Florey Neuroscience Institutes, Centre for Neuroscience, University of Melbourne, Parkville, Vic, 3010, Australia
    Neuromolecular Med 12:99-132. 2010
    ....
  9. doi request reprint Sex-specific disruptions in spatial memory and anhedonia in a "two hit" rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling
    Rachel A Hill
    Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia
    Hippocampus 24:1197-211. 2014
    ..Alterations to BDNF signaling may mediate the sex-specific effects of developmental stress on anhedonic behaviors...
  10. pmc Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility
    Gerry Z M Ma
    Multiple Sclerosis Division, Florey Neuroscience Institutes, University of Melbourne, Melbourne, Victoria, Australia
    PLoS ONE 6:e16964. 2011
    ..All 12 replicated SNPs were in strong linkage disequilibrium with each other. In combination, these data suggest the MERTK gene is a novel risk gene for MS susceptibility...
  11. doi request reprint Brain-derived neurotrophic factor expression is increased in the hippocampus of 5-HT(2C) receptor knockout mice
    Rachel A Hill
    Behavioral Neuroscience Laboratory, Mental Health Research Institute, Parkville, Victoria, Australia 3052
    Hippocampus 21:434-45. 2011
    ..05). In conclusion, loss of 5-HT(2C) receptor expression leads to a marked and selective increase in levels of the mature form of BDNF in the hippocampus. Despite this marked increase, 5-HT(2C) KO show only subtle behavioral changes...