Mandvi Bharadwaj

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. doi request reprint Detection and characterisation of alloreactive T cells
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Vic, Australia
    Methods Mol Biol 882:309-37. 2012
  2. doi request reprint TCD8 response in diverse outcomes of recurrent exposure to hepatitis C virus
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia
    Immunol Cell Biol 87:464-72. 2009
  3. doi request reprint Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Annu Rev Pharmacol Toxicol 52:401-31. 2012
  4. doi request reprint Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
    Diana Chessman
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Immunity 28:822-32. 2008
  5. doi request reprint Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
    Patricia T Illing
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    Nature 486:554-8. 2012
  6. doi request reprint Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response
    Duangtawan Thammanichanond
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    Clin Immunol 128:329-39. 2008
  7. doi request reprint High incidence of hepatitis C virus reinfection in a cohort of injecting drug users
    Campbell Kynoch Aitken
    Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
    Hepatology 48:1746-52. 2008
  8. ncbi request reprint Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: a preventative vaccine strategy
    Joseph Torresi
    Department of Medicine RMH WH, University of Melbourne, Centre for Medical Research, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia
    Curr Drug Targets 5:41-56. 2004
  9. doi request reprint Nucleoprotein of influenza A virus is a major target of immunodominant CD8+ T-cell responses
    Emma Grant
    Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Melbourne, Victoria, Australia
    Immunol Cell Biol 91:184-94. 2013
  10. pmc Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor
    Rangsima Reantragoon
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    J Exp Med 209:761-74. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint Detection and characterisation of alloreactive T cells
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Vic, Australia
    Methods Mol Biol 882:309-37. 2012
    ....
  2. doi request reprint TCD8 response in diverse outcomes of recurrent exposure to hepatitis C virus
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia
    Immunol Cell Biol 87:464-72. 2009
    ....
  3. doi request reprint Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex
    Mandvi Bharadwaj
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Annu Rev Pharmacol Toxicol 52:401-31. 2012
    ..Recent findings have begun to unearth the mechanistic basis for these HLA associations, and here we review recent advances in the field of HLA-associated drug hypersensitivities...
  4. doi request reprint Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
    Diana Chessman
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    Immunity 28:822-32. 2008
    ....
  5. doi request reprint Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
    Patricia T Illing
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    Nature 486:554-8. 2012
    ....
  6. doi request reprint Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response
    Duangtawan Thammanichanond
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    Clin Immunol 128:329-39. 2008
    ..These findings provide an effective approach for the expansion of HCV-specific CTLs from PBMCs of HCV-infected patients and have potential for immunotherapeutic/vaccine development...
  7. doi request reprint High incidence of hepatitis C virus reinfection in a cohort of injecting drug users
    Campbell Kynoch Aitken
    Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia
    Hepatology 48:1746-52. 2008
    ..This result has important implications for the future development of an HCV vaccine...
  8. ncbi request reprint Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: a preventative vaccine strategy
    Joseph Torresi
    Department of Medicine RMH WH, University of Melbourne, Centre for Medical Research, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia
    Curr Drug Targets 5:41-56. 2004
    ..The problems are further compounded by difficulties in growing the virus in vitro and the lack of a suitable and economical animal model...
  9. doi request reprint Nucleoprotein of influenza A virus is a major target of immunodominant CD8+ T-cell responses
    Emma Grant
    Department of Microbiology and Immunology, University of Melbourne, Royal Parade, Melbourne, Victoria, Australia
    Immunol Cell Biol 91:184-94. 2013
    ....
  10. pmc Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor
    Rangsima Reantragoon
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    J Exp Med 209:761-74. 2012
    ..This candidate docking mode contrasts with that of the NKT TCR-CD1d-antigen interaction, in which both the α and β chain of the NKT TCR is required for ligation above the F'-pocket of CD1d...
  11. pmc A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
    Lars Kjer-Nielsen
    Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria 3010, Australia
    J Exp Med 203:661-73. 2006
    ..The findings define a structural basis for the selection of the semi-invariant alphabeta TCR and the unique antigen specificity of NKT cells...
  12. pmc High rates of hepatitis C virus reinfection and spontaneous clearance of reinfection in people who inject drugs: a prospective cohort study
    Rachel Sacks-Davis
    Centre for Population Health, Burnet Institute, Melbourne, Victoria, Australia Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia Centre for Excellence into Injecting Drug Use, Burnet Institute, Melbourne, Victoria, Australia
    PLoS ONE 8:e80216. 2013
    ..Public health campaigns about the risks of hepatitis C reinfection are required. ..
  13. pmc Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
    Danielle Zernich
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia
    J Exp Med 200:13-24. 2004
    ..These findings unveil a new layer of MHC polymorphism that affects the generic pathway of Ag loading, revealing an unsuspected evolutionary trade-off in selection for optimal HLA class I loading versus effective pathogen evasion...